Showing entry for Ras-related GTP-binding protein A


　 　 　 　 　 　 　 　 　 　 　 　
General Target Information
BXGT IdBXGT025523
Protein NameRas-related GTP-binding protein A
Uniport IdQ7L523
GeneRRAGA
Gene Id10670
DomainGtr1_RagA
Pfam PF04670  
OrganismHomo sapiens (Human)
Target protein  affiliated  biological  pathways
KEGG
Class Subclass KEGG Id Pathway Name
4. Cellular Processes 4.1 Transport and catabolism hsa04140 Autophagy - animal
3. Environmental Information Processing 3.2 Signal transduction hsa04150 mTOR signaling pathway
Gene Ontology
GO Type GO Id Gene Ontology
Biological Process GO:0006915 apoptotic process
Biological Process GO:0007050 cell cycle arrest
Biological Process GO:0008219 cell death
Biological Process GO:0034613 cellular protein localization
Biological Process GO:0034198 cellular response to amino acid starvation
Biological Process GO:0071230 cellular response to amino acid stimulus
Biological Process GO:0009267 cellular response to starvation
Biological Process GO:0019048 modulation by virus of host process
Biological Process GO:0010507 negative regulation of autophagy
Biological Process GO:1904263 positive regulation of TORC1 signaling
Biological Process GO:0032008 positive regulation of TOR signaling
Biological Process GO:0016567 protein ubiquitination
Biological Process GO:0010506 regulation of autophagy
Biological Process GO:0016241 regulation of macroautophagy
molecular function GO:0003924 GTPase activity
molecular function GO:0005525 GTP binding
molecular function GO:0051219 phosphoprotein binding
molecular function GO:0046982 protein heterodimerization activity
molecular function GO:0042803 protein homodimerization activity
molecular function GO:0031625 ubiquitin protein ligase binding
cellular component GO:0005737 cytoplasm
cellular component GO:0005829 cytosol
cellular component GO:0034448 EGO complex
cellular component GO:1990131 Gtr1-Gtr2 GTPase complex
cellular component GO:0005765 lysosomal membrane
cellular component GO:0005764 lysosome
cellular component GO:0005634 nucleus
Reactome
Pathway Id Pathway Name
R-HSA-1257604 PIP3 activates AKT signaling
R-HSA-162582 Signal Transduction
R-HSA-1632852 Macroautophagy
R-HSA-165159 MTOR signalling
R-HSA-166208 mTORC1-mediated signalling
R-HSA-212436 Generic Transcription Pathway
R-HSA-2262752 Cellular responses to stress
R-HSA-3700989 Transcriptional Regulation by TP53
R-HSA-380972 Energy dependent regulation of mTOR by LKB1-AMPK
R-HSA-392499 Metabolism of proteins
R-HSA-5628897 TP53 Regulates Metabolic Genes
R-HSA-597592 Post-translational protein modification
R-HSA-6807070 PTEN Regulation
R-HSA-73857 RNA Polymerase II Transcription
R-HSA-74160 Gene expression (Transcription)
R-HSA-8852135 Protein ubiquitination
R-HSA-8866654 E3 ubiquitin ligases ubiquitinate target proteins
R-HSA-8943724 Regulation of PTEN gene transcription
R-HSA-8953897 Cellular responses to external stimuli
R-HSA-9006925 Intracellular signaling by second messengers
R-HSA-9612973 Autophagy
R-HSA-9639288 Amino acids regulate mTORC1
Target protein-related  diseases
Disease
CUI Id BXGD Id Disease Name Disease Class
C0006826 BXGD000408 Malignant Neoplasms Neoplasms
C0011206 BXGD000703 Delirium Pathological Conditions, Signs and Symptoms; Nervous System Diseases; Mental Disorders; Behavior and Behavior Mechanisms
C0014457 BXGD000915 Eosinophilia Hemic and Lymphatic Diseases
C0027651 BXGD002009 Neoplasms Neoplasms
C0206141 BXGD004160 Idiopathic Hypereosinophilic Syndrome Hemic and Lymphatic Diseases
C0206142 BXGD004161 Eosinophilic leukemia Hemic and Lymphatic Diseases
C0263662 BXGD005339 Disseminated eosinophilic collagen disease Skin and Connective Tissue Diseases
C0346421 BXGD007827 Chronic eosinophilic leukemia Neoplasms; Hemic and Lymphatic Diseases
C0745091 BXGD010113 Hypereosinophilia Hemic and Lymphatic Diseases
C1306459 BXGD012361 Primary malignant neoplasm Neoplasms
C1306759 BXGD012374 Eosinophilic disorder Hemic and Lymphatic Diseases
C1540912 BXGD013349 Hypereosinophilic syndrome Hemic and Lymphatic Diseases
Target protein-related  compounds
Compounds
BXGC Id Compound Name Strcuture Molecular Weight
BXGC0002588 Magnesium 24.31
BXGC0026148 1,5-pentanediol 104.08
BXGC0048845 Guanosine Triphosphate 522.99
The  target protein-related  foods
Foods
BXGF Id Food Name Scientific Name Food Group Number of compound? Number of compound in food, higher numbers indicate the food are more associated with the protein