Showing entry for Dolichyl-diphosphooligosaccharide--protein glycosyltransferase subunit STT3A


　 　 　 　 　 　 　 　 　 　 　 　
General Target Information
BXGT IdBXGT025531
Protein NameDolichyl-diphosphooligosaccharide--protein glycosyltransferase subunit STT3A
Uniport IdP46977
GeneSTT3A
Gene Id3703
DomainSTT3
Pfam PF02516  
OrganismHomo sapiens (Human)
Target protein  affiliated  biological  pathways
KEGG
Class Subclass KEGG Id Pathway Name
1. Metabolism 1.7 Glycan biosynthesis and metabolism hsa00510 N-Glycan biosynthesis
1. Metabolism 1.0 Global and overview maps hsa01100 Metabolic pathways
2. Genetic Information Processing 2.3 Folding, sorting and degradation hsa04141 Protein processing in endoplasmic reticulum
Gene Ontology
GO Type GO Id Gene Ontology
Biological Process GO:0043686 co-translational protein modification
Biological Process GO:0043687 post-translational protein modification
Biological Process GO:0006487 protein N-linked glycosylation
Biological Process GO:0018279 protein N-linked glycosylation via asparagine
molecular function GO:0004579 dolichyl-diphosphooligosaccharide-protein glycotransferase activity
molecular function GO:0046872 metal ion binding
cellular component GO:0005789 endoplasmic reticulum membrane
cellular component GO:0016021 integral component of membrane
cellular component GO:0016020 membrane
cellular component GO:0008250 oligosaccharyltransferase complex
cellular component GO:0035000 oligosaccharyltransferase III complex
Reactome
Pathway Id Pathway Name
R-HSA-1643685 Disease
R-HSA-392499 Metabolism of proteins
R-HSA-446203 Asparagine N-linked glycosylation
R-HSA-5663205 Infectious disease
R-HSA-597592 Post-translational protein modification
R-HSA-9679506 SARS-CoV Infections
R-HSA-9694516 SARS-CoV-2 Infection
R-HSA-9694548 Maturation of spike protein
R-HSA-9694635 Translation of structural proteins
Target protein-related  diseases
Disease
CUI Id BXGD Id Disease Name Disease Class
C0003175 BXGD000187 Anthrax disease Infections
C0005586 BXGD000315 Bipolar Disorder Mental Disorders
C0007102 BXGD000425 Malignant tumor of colon Digestive System Diseases; Neoplasms
C0007114 BXGD000431 Malignant neoplasm of skin Neoplasms; Skin and Connective Tissue Diseases
C0007847 BXGD000492 Malignant tumor of cervix Neoplasms; Female Urogenital Diseases and Pregnancy Complications
C0008074 BXGD000519 Child Development Disorders, Pervasive Mental Disorders
C0010417 BXGD000670 Cryptorchidism Congenital, Hereditary, and Neonatal Diseases and Abnormalities; Male Urogenital Diseases; Endocrine System Diseases
C0014522 BXGD000922 Epidermodysplasia Verruciformis Infections; Skin and Connective Tissue Diseases
C0015544 BXGD001003 Failure to Thrive Pathological Conditions, Signs and Symptoms
C0017661 BXGD001139 IGA Glomerulonephritis Female Urogenital Diseases and Pregnancy Complications; Male Urogenital Diseases; Immune System Diseases
C0019348 BXGD001325 Herpes Simplex Infections Infections; Skin and Connective Tissue Diseases
C0025958 BXGD001882 Microcephaly Congenital, Hereditary, and Neonatal Diseases and Abnormalities; Musculoskeletal Diseases; Nervous System Diseases
C0036341 BXGD002600 Schizophrenia Mental Disorders
C0036572 BXGD002625 Seizures Pathological Conditions, Signs and Symptoms; Nervous System Diseases
C0041228 BXGD002900 African Trypanosomiasis Infections
C0206682 BXGD004237 Follicular thyroid carcinoma Neoplasms
C0206694 BXGD004245 Mucoepidermoid Carcinoma Neoplasms
C0232466 BXGD004543 Feeding difficulties
C0282577 BXGD006816 Congenital Disorders of Glycosylation Congenital, Hereditary, and Neonatal Diseases and Abnormalities; Nutritional and Metabolic Diseases
C0302592 BXGD006851 Cervix carcinoma Neoplasms; Female Urogenital Diseases and Pregnancy Complications
C0339789 BXGD007282 Congenital deafness Pathological Conditions, Signs and Symptoms; Congenital, Hereditary, and Neonatal Diseases and Abnormalities; Female Urogenital Diseases and Pregnancy Complications; Nervous System Diseases; Otorhinolaryngologic Diseases
C0403814 BXGD008313 Congenital bilateral aplasia of vas deferens Male Urogenital Diseases
C0424605 BXGD008535 Developmental delay (disorder) Mental Disorders
C0431659 BXGD008699 Hypoplasia of scrotum
C0553723 BXGD009416 Squamous cell carcinoma of skin Neoplasms; Skin and Connective Tissue Diseases
C0557874 BXGD009444 Global developmental delay
C0699790 BXGD009866 Colon Carcinoma Digestive System Diseases; Neoplasms
C0740279 BXGD009973 Cerebellar atrophy
C0751495 BXGD010473 Seizures, Focal Pathological Conditions, Signs and Symptoms; Nervous System Diseases
C1263846 BXGD011897 Attention deficit hyperactivity disorder Mental Disorders
C1269683 BXGD012001 Major Depressive Disorder Mental Disorders
C1387005 BXGD012953 Penis agenesis Male Urogenital Diseases
C1837458 BXGD014233 Impaired smooth pursuit
C1858120 BXGD015774 Generalized hypotonia Pathological Conditions, Signs and Symptoms; Nervous System Diseases
C3714756 BXGD019429 Intellectual Disability Pathological Conditions, Signs and Symptoms; Nervous System Diseases; Mental Disorders; Behavior and Behavior Mechanisms
C3810062 BXGD019635 Congenital disorder of glycosylation type 1w Congenital, Hereditary, and Neonatal Diseases and Abnormalities; Nutritional and Metabolic Diseases
C3854222 BXGD019826 Human immunodeficiency virus (HIV) II infection category B1
C4022946 BXGD021042 Abnormal glycosylation
C4048328 BXGD021903 cervical cancer Neoplasms; Female Urogenital Diseases and Pregnancy Complications
Target protein-related  compounds
Compounds
BXGC Id Compound Name Strcuture Molecular Weight
BXGC0002588 Magnesium 24.31
The  target protein-related  foods
Foods
BXGF Id Food Name Scientific Name Food Group Number of compound? Number of compound in food, higher numbers indicate the food are more associated with the protein