Showing entry for Dolichyl-diphosphooligosaccharide--protein glycosyltransferase subunit 1


　 　 　 　 　 　 　 　 　 　 　 　
General Target Information
BXGT IdBXGT025532
Protein NameDolichyl-diphosphooligosaccharide--protein glycosyltransferase subunit 1
Uniport IdP04843
GeneRPN1
Gene Id6184
DomainRibophorin_I
Pfam PF04597  
OrganismHomo sapiens (Human)
Target protein  affiliated  biological  pathways
KEGG
Class Subclass KEGG Id Pathway Name
1. Metabolism 1.7 Glycan biosynthesis and metabolism hsa00510 N-Glycan biosynthesis
1. Metabolism 1.0 Global and overview maps hsa01100 Metabolic pathways
2. Genetic Information Processing 2.3 Folding, sorting and degradation hsa04141 Protein processing in endoplasmic reticulum
Gene Ontology
GO Type GO Id Gene Ontology
Biological Process GO:0006464 cellular protein modification process
Biological Process GO:0006487 protein N-linked glycosylation
Biological Process GO:0018279 protein N-linked glycosylation via asparagine
molecular function GO:0003723 RNA binding
cellular component GO:0005829 cytosol
cellular component GO:0005783 endoplasmic reticulum
cellular component GO:0005789 endoplasmic reticulum membrane
cellular component GO:0016021 integral component of membrane
cellular component GO:0042470 melanosome
cellular component GO:0016020 membrane
cellular component GO:0008250 oligosaccharyltransferase complex
cellular component GO:0005791 rough endoplasmic reticulum
Reactome
Pathway Id Pathway Name
R-HSA-1643685 Disease
R-HSA-1799339 SRP-dependent cotranslational protein targeting to membrane
R-HSA-392499 Metabolism of proteins
R-HSA-392499 Metabolism of proteins
R-HSA-446203 Asparagine N-linked glycosylation
R-HSA-5663205 Infectious disease
R-HSA-597592 Post-translational protein modification
R-HSA-72766 Translation
R-HSA-9679506 SARS-CoV Infections
R-HSA-9694516 SARS-CoV-2 Infection
R-HSA-9694548 Maturation of spike protein
R-HSA-9694635 Translation of structural proteins
Target protein-related  diseases
Disease
CUI Id BXGD Id Disease Name Disease Class
C0006413 BXGD000397 Burkitt Lymphoma Neoplasms; Infections; Immune System Diseases; Hemic and Lymphatic Diseases
C0010054 BXGD000647 Coronary Arteriosclerosis Cardiovascular Diseases
C0010068 BXGD000648 Coronary heart disease Cardiovascular Diseases
C0022661 BXGD001572 Kidney Failure, Chronic Female Urogenital Diseases and Pregnancy Complications; Male Urogenital Diseases
C0023418 BXGD001642 leukemia Neoplasms
C0023467 BXGD001658 Leukemia, Myelocytic, Acute Neoplasms
C0023508 BXGD001675 White Blood Cell Count procedure
C0200637 BXGD004042 Monocyte count procedure
C0200638 BXGD004043 Eosinophil count procedure
C0200641 BXGD004044 Blood basophil count (lab test)
C0750880 BXGD010239 Monocyte count result
C1332977 BXGD012569 Childhood Leukemia Neoplasms
C1956346 BXGD016627 Coronary Artery Disease Cardiovascular Diseases
C2985280 BXGD018223 Blood Protein Measurement
Target protein-related  compounds
Compounds
BXGC Id Compound Name Strcuture Molecular Weight
BXGC0002588 Magnesium 24.31
The  target protein-related  foods
Foods
BXGF Id Food Name Scientific Name Food Group Number of compound? Number of compound in food, higher numbers indicate the food are more associated with the protein