Showing entry for Dolichyl-diphosphooligosaccharide--protein glycosyltransferase subunit STT3B


　 　 　 　 　 　 　 　 　 　 　 　
General Target Information
BXGT IdBXGT025533
Protein NameDolichyl-diphosphooligosaccharide--protein glycosyltransferase subunit STT3B
Uniport IdQ8TCJ2
GeneSTT3B
Gene Id201595
DomainSTT3
Pfam PF02516  
OrganismHomo sapiens (Human)
Target protein  affiliated  biological  pathways
KEGG
Class Subclass KEGG Id Pathway Name
1. Metabolism 1.7 Glycan biosynthesis and metabolism hsa00510 N-Glycan biosynthesis
1. Metabolism 1.0 Global and overview maps hsa01100 Metabolic pathways
2. Genetic Information Processing 2.3 Folding, sorting and degradation hsa04141 Protein processing in endoplasmic reticulum
Gene Ontology
GO Type GO Id Gene Ontology
Biological Process GO:0043686 co-translational protein modification
Biological Process GO:0006516 glycoprotein catabolic process
Biological Process GO:0043687 post-translational protein modification
Biological Process GO:0006487 protein N-linked glycosylation
Biological Process GO:0018279 protein N-linked glycosylation via asparagine
Biological Process GO:0006986 response to unfolded protein
Biological Process GO:0030433 ubiquitin-dependent ERAD pathway
molecular function GO:0004579 dolichyl-diphosphooligosaccharide-protein glycotransferase activity
molecular function GO:0046872 metal ion binding
cellular component GO:0005783 endoplasmic reticulum
cellular component GO:0016021 integral component of membrane
cellular component GO:0016020 membrane
cellular component GO:0008250 oligosaccharyltransferase complex
cellular component GO:0034998 oligosaccharyltransferase I complex
cellular component GO:0032991 protein-containing complex
Reactome
Pathway Id Pathway Name
Target protein-related  diseases
Disease
CUI Id BXGD Id Disease Name Disease Class
C0010417 BXGD000670 Cryptorchidism Congenital, Hereditary, and Neonatal Diseases and Abnormalities; Male Urogenital Diseases; Endocrine System Diseases
C0011311 BXGD000714 Dengue Fever Infections
C0015544 BXGD001003 Failure to Thrive Pathological Conditions, Signs and Symptoms
C0015934 BXGD001026 Fetal Growth Retardation Pathological Conditions, Signs and Symptoms; Congenital, Hereditary, and Neonatal Diseases and Abnormalities; Female Urogenital Diseases and Pregnancy Complications
C0025958 BXGD001882 Microcephaly Congenital, Hereditary, and Neonatal Diseases and Abnormalities; Musculoskeletal Diseases; Nervous System Diseases
C0029124 BXGD002113 Optic Atrophy Eye Diseases; Nervous System Diseases
C0036572 BXGD002625 Seizures Pathological Conditions, Signs and Symptoms; Nervous System Diseases
C0040034 BXGD002836 Thrombocytopenia Hemic and Lymphatic Diseases
C0041228 BXGD002900 African Trypanosomiasis Infections
C0232466 BXGD004543 Feeding difficulties
C0232744 BXGD004561 Decreased liver function
C0282577 BXGD006816 Congenital Disorders of Glycosylation Congenital, Hereditary, and Neonatal Diseases and Abnormalities; Nutritional and Metabolic Diseases
C0424605 BXGD008535 Developmental delay (disorder) Mental Disorders
C0431659 BXGD008699 Hypoplasia of scrotum
C0476273 BXGD008986 Respiratory distress Pathological Conditions, Signs and Symptoms; Respiratory Tract Diseases
C0557874 BXGD009444 Global developmental delay
C0740279 BXGD009973 Cerebellar atrophy
C1387005 BXGD012953 Penis agenesis Male Urogenital Diseases
C1843392 BXGD014582 Death in childhood
C1858120 BXGD015774 Generalized hypotonia Pathological Conditions, Signs and Symptoms; Nervous System Diseases
C2931007 BXGD017933 Congenital disorder of glycosylation type 1X Congenital, Hereditary, and Neonatal Diseases and Abnormalities; Nutritional and Metabolic Diseases; Hemic and Lymphatic Diseases
C3266262 BXGD018600 Multiple Chronic Conditions Pathological Conditions, Signs and Symptoms
C3714756 BXGD019429 Intellectual Disability Pathological Conditions, Signs and Symptoms; Nervous System Diseases; Mental Disorders; Behavior and Behavior Mechanisms
C4022946 BXGD021042 Abnormal glycosylation
Target protein-related  compounds
Compounds
BXGC Id Compound Name Strcuture Molecular Weight
BXGC0002588 Magnesium 24.31
The  target protein-related  foods
Foods
BXGF Id Food Name Scientific Name Food Group Number of compound? Number of compound in food, higher numbers indicate the food are more associated with the protein