protein

Showing entry for DNA repair protein complementing XP-G cells

General Target Information
BXGT Id	BXGT025675
Protein Name	DNA repair protein complementing XP-G cells
Uniport Id	P28715
Gene	ERCC5
Gene Id	2073
Domain	XPG_I; XPG_N
Pfam	PF00867 PF00752
Organism	Homo sapiens (Human)

Target protein affiliated biological pathways

KEGG

Class	Subclass	KEGG Id	Pathway Name
2. Genetic Information Processing	2.4 Replication and repair	hsa03420	Nucleotide excision repair

Gene Ontology

GO Type	GO Id	Gene Ontology
Biological Process	GO:0043066	negative regulation of apoptotic process
Biological Process	GO:0006289	nucleotide-excision repair
Biological Process	GO:0033683	nucleotide-excision repair, DNA incision
Biological Process	GO:0006295	nucleotide-excision repair, DNA incision, 3'-to lesion
Biological Process	GO:0006296	nucleotide-excision repair, DNA incision, 5'-to lesion
Biological Process	GO:0006294	nucleotide-excision repair, preincision complex assembly
Biological Process	GO:0006293	nucleotide-excision repair, preincision complex stabilization
Biological Process	GO:0009411	response to UV
Biological Process	GO:0010225	response to UV-C
Biological Process	GO:0006283	transcription-coupled nucleotide-excision repair
Biological Process	GO:0009650	UV protection
molecular function	GO:0000405	bubble DNA binding
molecular function	GO:0003690	double-stranded DNA binding
molecular function	GO:0004520	endodeoxyribonuclease activity
molecular function	GO:0046872	metal ion binding
molecular function	GO:0044877	protein-containing complex binding
molecular function	GO:0042803	protein homodimerization activity
molecular function	GO:0047485	protein N-terminus binding
molecular function	GO:0000993	RNA polymerase II complex binding
molecular function	GO:0003697	single-stranded DNA binding
cellular component	GO:0005654	nucleoplasm
cellular component	GO:0000109	nucleotide-excision repair complex
cellular component	GO:0005634	nucleus

Reactome

Pathway Id	Pathway Name
R-HSA-5696395	Formation of Incision Complex in GG-NER
R-HSA-5696398	Nucleotide Excision Repair
R-HSA-5696399	Global Genome Nucleotide Excision Repair (GG-NER)
R-HSA-5696400	Dual Incision in GG-NER
R-HSA-6781827	Transcription-Coupled Nucleotide Excision Repair (TC-NER)
R-HSA-6782135	Dual incision in TC-NER
R-HSA-73894	DNA Repair

Target protein-related diseases

Disease

CUI Id	BXGD Id	Disease Name	Disease Class
C0001418	BXGD000050	Adenocarcinoma	Neoplasms
C0002170	BXGD000105	Alopecia	Pathological Conditions, Signs and Symptoms; Skin and Connective Tissue Diseases
C0003850	BXGD000225	Arteriosclerosis	Cardiovascular Diseases
C0003862	BXGD000230	Arthralgia	Pathological Conditions, Signs and Symptoms; Musculoskeletal Diseases
C0003886	BXGD000238	Arthrogryposis	Congenital, Hereditary, and Neonatal Diseases and Abnormalities; Musculoskeletal Diseases
C0004134	BXGD000256	Ataxia	Pathological Conditions, Signs and Symptoms; Nervous System Diseases
C0005684	BXGD000319	Malignant neoplasm of urinary bladder	Neoplasms; Female Urogenital Diseases and Pregnancy Complications; Male Urogenital Diseases
C0005695	BXGD000323	Bladder Neoplasm	Neoplasms; Female Urogenital Diseases and Pregnancy Complications; Male Urogenital Diseases
C0005741	BXGD000328	Blepharitis	Eye Diseases
C0006118	BXGD000372	Brain Neoplasms	Neoplasms; Nervous System Diseases
C0006142	BXGD000374	Malignant neoplasm of breast	Neoplasms; Skin and Connective Tissue Diseases
C0006625	BXGD000401	Cachexia	Pathological Conditions, Signs and Symptoms
C0006826	BXGD000408	Malignant Neoplasms	Neoplasms
C0007103	BXGD000426	Malignant neoplasm of endometrium	Neoplasms; Female Urogenital Diseases and Pregnancy Complications
C0007107	BXGD000428	Malignant neoplasm of larynx	Neoplasms; Respiratory Tract Diseases; Otorhinolaryngologic Diseases
C0007114	BXGD000431	Malignant neoplasm of skin	Neoplasms; Skin and Connective Tissue Diseases
C0007115	BXGD000432	Malignant neoplasm of thyroid	Neoplasms; Endocrine System Diseases
C0007117	BXGD000433	Basal cell carcinoma	Neoplasms
C0007131	BXGD000441	Non-Small Cell Lung Carcinoma	Neoplasms; Respiratory Tract Diseases
C0007137	BXGD000445	Squamous cell carcinoma	Neoplasms
C0008626	BXGD000559	Congenital chromosomal disease	Congenital, Hereditary, and Neonatal Diseases and Abnormalities
C0009081	BXGD000581	Congenital clubfoot	Congenital, Hereditary, and Neonatal Diseases and Abnormalities; Musculoskeletal Diseases
C0009207	BXGD000593	Cockayne Syndrome	Congenital, Hereditary, and Neonatal Diseases and Abnormalities; Nutritional and Metabolic Diseases; Musculoskeletal Diseases; Nervous System Diseases
C0009402	BXGD000605	Colorectal Carcinoma	Digestive System Diseases; Neoplasms
C0009676	BXGD000619	Confusion	Pathological Conditions, Signs and Symptoms; Nervous System Diseases; Behavior and Behavior Mechanisms
C0010068	BXGD000648	Coronary heart disease	Cardiovascular Diseases
C0010417	BXGD000670	Cryptorchidism	Congenital, Hereditary, and Neonatal Diseases and Abnormalities; Male Urogenital Diseases; Endocrine System Diseases
C0012569	BXGD000777	Diplopia	Pathological Conditions, Signs and Symptoms; Eye Diseases; Nervous System Diseases
C0013336	BXGD000815	Dwarfism	Congenital, Hereditary, and Neonatal Diseases and Abnormalities; Musculoskeletal Diseases; Endocrine System Diseases
C0013362	BXGD000817	Dysarthria	Pathological Conditions, Signs and Symptoms; Nervous System Diseases
C0013592	BXGD000857	Ectropion	Eye Diseases
C0013604	BXGD000859	Edema	Pathological Conditions, Signs and Symptoms
C0014390	BXGD000913	Entropion	Eye Diseases
C0014859	BXGD000961	Esophageal Neoplasms	Digestive System Diseases; Neoplasms
C0015230	BXGD000969	Exanthema	Skin and Connective Tissue Diseases
C0015414	BXGD000989	Eye Neoplasms	Neoplasms; Eye Diseases
C0015544	BXGD001003	Failure to Thrive	Pathological Conditions, Signs and Symptoms
C0015625	BXGD001006	Fanconi Anemia	Congenital, Hereditary, and Neonatal Diseases and Abnormalities; Nutritional and Metabolic Diseases; Hemic and Lymphatic Diseases
C0015672	BXGD001011	Fatigue	Pathological Conditions, Signs and Symptoms
C0015934	BXGD001026	Fetal Growth Retardation	Pathological Conditions, Signs and Symptoms; Congenital, Hereditary, and Neonatal Diseases and Abnormalities; Female Urogenital Diseases and Pregnancy Complications
C0015967	BXGD001030	Fever	Pathological Conditions, Signs and Symptoms
C0016689	BXGD001073	Freckles	Skin and Connective Tissue Diseases
C0016842	BXGD001083	Congenital pectus excavatum	Congenital, Hereditary, and Neonatal Diseases and Abnormalities; Musculoskeletal Diseases
C0017154	BXGD001097	Gastritis, Atrophic	Digestive System Diseases
C0017638	BXGD001132	Glioma	Neoplasms
C0018553	BXGD001203	Hamartoma Syndrome, Multiple	Congenital, Hereditary, and Neonatal Diseases and Abnormalities; Neoplasms
C0018784	BXGD001220	Sensorineural Hearing Loss (disorder)	Pathological Conditions, Signs and Symptoms; Nervous System Diseases; Otorhinolaryngologic Diseases
C0020255	BXGD001369	Hydrocephalus	Nervous System Diseases
C0020619	BXGD001447	Hypogonadism	Endocrine System Diseases
C0022568	BXGD001552	Keratitis	Eye Diseases
C0023051	BXGD001602	Laryngeal Diseases	Respiratory Tract Diseases; Otorhinolaryngologic Diseases
C0023269	BXGD001627	leiomyosarcoma	Neoplasms
C0023418	BXGD001642	leukemia	Neoplasms
C0023467	BXGD001658	Leukemia, Myelocytic, Acute	Neoplasms
C0023530	BXGD001683	Leukopenia	Hemic and Lymphatic Diseases
C0024121	BXGD001735	Lung Neoplasms	Neoplasms; Respiratory Tract Diseases
C0024299	BXGD001758	Lymphoma	Neoplasms; Immune System Diseases; Hemic and Lymphatic Diseases
C0024305	BXGD001763	Lymphoma, Non-Hodgkin	Neoplasms; Immune System Diseases; Hemic and Lymphatic Diseases
C0024623	BXGD001791	Malignant neoplasm of stomach	Digestive System Diseases; Neoplasms
C0025202	BXGD001832	melanoma	Neoplasms
C0025286	BXGD001850	Meningioma	Neoplasms; Nervous System Diseases
C0025958	BXGD001882	Microcephaly	Congenital, Hereditary, and Neonatal Diseases and Abnormalities; Musculoskeletal Diseases; Nervous System Diseases
C0025990	BXGD001884	Micrognathism	Congenital, Hereditary, and Neonatal Diseases and Abnormalities; Musculoskeletal Diseases; Stomatognathic Diseases
C0026010	BXGD001886	Microphthalmos	Congenital, Hereditary, and Neonatal Diseases and Abnormalities; Eye Diseases
C0026769	BXGD001930	Multiple Sclerosis	Immune System Diseases; Nervous System Diseases
C0026826	BXGD001935	Muscle Hypertonia	Pathological Conditions, Signs and Symptoms; Nervous System Diseases
C0026827	BXGD001936	Muscle hypotonia	Pathological Conditions, Signs and Symptoms; Nervous System Diseases
C0026838	BXGD001938	Muscle Spasticity	Pathological Conditions, Signs and Symptoms; Musculoskeletal Diseases; Nervous System Diseases
C0027627	BXGD002006	Neoplasm Metastasis	Pathological Conditions, Signs and Symptoms; Neoplasms
C0027651	BXGD002009	Neoplasms	Neoplasms
C0027819	BXGD002043	Neuroblastoma	Neoplasms
C0027947	BXGD002061	Neutropenia	Hemic and Lymphatic Diseases
C0027962	BXGD002064	Melanocytic nevus	Neoplasms
C0028738	BXGD002081	Nystagmus	Eye Diseases; Nervous System Diseases
C0029124	BXGD002113	Optic Atrophy	Eye Diseases; Nervous System Diseases
C0029463	BXGD002160	Osteosarcoma	Neoplasms
C0030354	BXGD002214	Papilloma	Neoplasms
C0033578	BXGD002408	Prostatic Neoplasms	Neoplasms; Male Urogenital Diseases
C0033999	BXGD002448	Pterygium	Eye Diseases
C0035309	BXGD002530	Retinal Diseases	Eye Diseases
C0036341	BXGD002600	Schizophrenia	Mental Disorders
C0036572	BXGD002625	Seizures	Pathological Conditions, Signs and Symptoms; Nervous System Diseases
C0037772	BXGD002703	Spastic Paraplegia	Pathological Conditions, Signs and Symptoms; Nervous System Diseases
C0038379	BXGD002752	Strabismus	Eye Diseases; Nervous System Diseases
C0038454	BXGD002760	Cerebrovascular accident	Nervous System Diseases; Cardiovascular Diseases
C0039101	BXGD002790	synovial sarcoma	Neoplasms
C0039483	BXGD002813	Giant Cell Arteritis	Skin and Connective Tissue Diseases; Immune System Diseases; Nervous System Diseases; Cardiovascular Diseases
C0040136	BXGD002845	Thyroid Neoplasm	Neoplasms; Endocrine System Diseases
C0041834	BXGD002935	Erythema	Pathological Conditions, Signs and Symptoms; Skin and Connective Tissue Diseases
C0042109	BXGD002957	Urticaria	Skin and Connective Tissue Diseases; Immune System Diseases
C0043346	BXGD003043	Xeroderma Pigmentosum	Congenital, Hereditary, and Neonatal Diseases and Abnormalities; Neoplasms; Nutritional and Metabolic Diseases; Skin and Connective Tissue Diseases
C0079588	BXGD003084	Ichthyosis, X-Linked	Congenital, Hereditary, and Neonatal Diseases and Abnormalities; Nutritional and Metabolic Diseases; Skin and Connective Tissue Diseases
C0079731	BXGD003087	B-Cell Lymphomas	Neoplasms; Immune System Diseases; Hemic and Lymphatic Diseases
C0079744	BXGD003090	Diffuse Large B-Cell Lymphoma	Neoplasms; Immune System Diseases; Hemic and Lymphatic Diseases
C0079772	BXGD003099	T-Cell Lymphoma	Neoplasms; Immune System Diseases; Hemic and Lymphatic Diseases
C0085636	BXGD003218	Photophobia	Pathological Conditions, Signs and Symptoms; Eye Diseases; Nervous System Diseases
C0086543	BXGD003294	Cataract	Eye Diseases
C0149931	BXGD003388	Migraine Disorders	Nervous System Diseases
C0151514	BXGD003429	Atrophic condition of skin	Pathological Conditions, Signs and Symptoms; Skin and Connective Tissue Diseases
C0151611	BXGD003447	Electroencephalogram abnormal	Nervous System Diseases
C0151779	BXGD003473	Cutaneous Melanoma	Neoplasms; Skin and Connective Tissue Diseases
C0151908	BXGD003502	Dry skin	Skin and Connective Tissue Diseases
C0152018	BXGD003518	Esophageal carcinoma	Digestive System Diseases; Neoplasms
C0152025	BXGD003521	Polyneuropathy	Nervous System Diseases
C0152233	BXGD003565	Congenital ankyloblepharon	Congenital, Hereditary, and Neonatal Diseases and Abnormalities; Eye Diseases
C0162298	BXGD003933	Joint stiffness	Musculoskeletal Diseases
C0178874	BXGD004037	Tumor Progression	Pathological Conditions, Signs and Symptoms
C0206634	BXGD004199	Liposarcoma, Myxoid	Neoplasms
C0206677	BXGD004234	Adenomatous Polyps	Neoplasms
C0220722	BXGD004331	Cerebrooculofacioskeletal Syndrome 1	Congenital, Hereditary, and Neonatal Diseases and Abnormalities; Nutritional and Metabolic Diseases; Musculoskeletal Diseases; Nervous System Diseases
C0234133	BXGD004624	Extrapyramidal sign
C0235031	BXGD004714	Neurologic Symptoms	Pathological Conditions, Signs and Symptoms; Nervous System Diseases
C0235659	BXGD004763	Reduced fetal movement	Congenital, Hereditary, and Neonatal Diseases and Abnormalities; Female Urogenital Diseases and Pregnancy Complications
C0235974	BXGD004796	Pancreatic carcinoma	Digestive System Diseases; Neoplasms; Endocrine System Diseases
C0238463	BXGD004938	Papillary thyroid carcinoma	Neoplasms; Endocrine System Diseases
C0238621	BXGD004947	Aminoaciduria	Congenital, Hereditary, and Neonatal Diseases and Abnormalities; Nutritional and Metabolic Diseases
C0239105	BXGD004962	Conjunctival telangiectasis
C0239234	BXGD004974	Low set ears
C0240912	BXGD005062	Vertical Talus	Congenital, Hereditary, and Neonatal Diseases and Abnormalities; Musculoskeletal Diseases
C0241355	BXGD005092	Small testicle
C0242379	BXGD005157	Malignant neoplasm of lung	Neoplasms; Respiratory Tract Diseases
C0262444	BXGD005244	Abnormality of the dentition	Congenital, Hereditary, and Neonatal Diseases and Abnormalities; Stomatognathic Diseases
C0268135	BXGD005831	Xeroderma pigmentosum, group A	Congenital, Hereditary, and Neonatal Diseases and Abnormalities; Neoplasms; Nutritional and Metabolic Diseases; Skin and Connective Tissue Diseases
C0268138	BXGD005833	Xeroderma Pigmentosum, Complementation Group D	Congenital, Hereditary, and Neonatal Diseases and Abnormalities; Neoplasms; Nutritional and Metabolic Diseases; Skin and Connective Tissue Diseases
C0268141	BXGD005835	Xeroderma pigmentosum, group G	Congenital, Hereditary, and Neonatal Diseases and Abnormalities; Neoplasms; Nutritional and Metabolic Diseases; Skin and Connective Tissue Diseases
C0270685	BXGD006084	Cerebral calcification	Nutritional and Metabolic Diseases; Nervous System Diseases
C0270922	BXGD006134	Peripheral demyelinating neuropathy	Immune System Diseases; Nervous System Diseases
C0271160	BXGD006166	Cortical cataract	Eye Diseases
C0278689	BXGD006563	Recurrent ovarian cancer	Neoplasms; Female Urogenital Diseases and Pregnancy Complications; Endocrine System Diseases
C0278996	BXGD006621	Malignant Head and Neck Neoplasm	Neoplasms
C0279626	BXGD006657	Squamous cell carcinoma of esophagus	Digestive System Diseases; Neoplasms
C0280313	BXGD006737	Squamous cell carcinoma of oropharynx	Neoplasms; Stomatognathic Diseases; Otorhinolaryngologic Diseases
C0302592	BXGD006851	Cervix carcinoma	Neoplasms; Female Urogenital Diseases and Pregnancy Complications
C0333983	BXGD006975	Hyperplastic Polyp	Pathological Conditions, Signs and Symptoms
C0338656	BXGD007211	Impaired cognition	Mental Disorders
C0339182	BXGD007229	Ankyloblepharon	Congenital, Hereditary, and Neonatal Diseases and Abnormalities; Eye Diseases
C0346647	BXGD007832	Malignant neoplasm of pancreas	Digestive System Diseases; Neoplasms; Endocrine System Diseases
C0349506	BXGD007912	Photosensitivity of skin	Skin and Connective Tissue Diseases
C0349588	BXGD007933	Short stature
C0376358	BXGD007992	Malignant neoplasm of prostate	Neoplasms; Male Urogenital Diseases
C0392777	BXGD008068	Poikiloderma	Pathological Conditions, Signs and Symptoms
C0392784	BXGD008069	Dermatofibrosarcoma Protuberans	Neoplasms
C0409348	BXGD008384	Flexion contracture of proximal interphalangeal joint
C0423250	BXGD008476	Corneal stromal opacities	Eye Diseases
C0423757	BXGD008504	Thin skin
C0476089	BXGD008977	Endometrial Carcinoma	Neoplasms; Female Urogenital Diseases and Pregnancy Complications
C0520680	BXGD009102	Sleep Apnea, Central	Respiratory Tract Diseases; Nervous System Diseases
C0521525	BXGD009139	Short neck
C0541764	BXGD009259	Delayed bone age
C0546837	BXGD009343	Malignant neoplasm of esophagus	Digestive System Diseases; Neoplasms
C0549473	BXGD009384	Thyroid carcinoma	Neoplasms; Endocrine System Diseases
C0549523	BXGD009386	Oropharynx (excludes nasopharynx)
C0553723	BXGD009416	Squamous cell carcinoma of skin	Neoplasms; Skin and Connective Tissue Diseases
C0557874	BXGD009444	Global developmental delay
C0585442	BXGD009593	Osteosarcoma of bone	Neoplasms
C0595989	BXGD009632	Carcinoma of larynx	Neoplasms; Respiratory Tract Diseases; Otorhinolaryngologic Diseases
C0596263	BXGD009639	Carcinogenesis	Pathological Conditions, Signs and Symptoms; Neoplasms
C0600139	BXGD009695	Prostate carcinoma	Neoplasms; Male Urogenital Diseases
C0678222	BXGD009749	Breast Carcinoma	Neoplasms; Skin and Connective Tissue Diseases
C0684249	BXGD009790	Carcinoma of lung	Neoplasms; Respiratory Tract Diseases
C0686619	BXGD009835	Secondary malignant neoplasm of lymph node	Pathological Conditions, Signs and Symptoms; Neoplasms
C0699791	BXGD009867	Stomach Carcinoma	Digestive System Diseases; Neoplasms
C0699885	BXGD009869	Carcinoma of bladder	Neoplasms; Female Urogenital Diseases and Pregnancy Complications; Male Urogenital Diseases
C0700095	BXGD009875	Central neuroblastoma	Neoplasms; Nervous System Diseases
C0728829	BXGD009917	Congenital pes cavus	Congenital, Hereditary, and Neonatal Diseases and Abnormalities; Skin and Connective Tissue Diseases; Musculoskeletal Diseases
C0740279	BXGD009973	Cerebellar atrophy
C0751039	BXGD010302	Cockayne Syndrome, Type I	Congenital, Hereditary, and Neonatal Diseases and Abnormalities; Nutritional and Metabolic Diseases; Musculoskeletal Diseases; Nervous System Diseases
C0751688	BXGD010551	Malignant Squamous Cell Neoplasm	Neoplasms
C0870082	BXGD011309	Hyperkeratosis	Pathological Conditions, Signs and Symptoms; Skin and Connective Tissue Diseases
C0919267	BXGD011426	ovarian neoplasm	Neoplasms; Female Urogenital Diseases and Pregnancy Complications; Endocrine System Diseases
C1140680	BXGD011718	Malignant neoplasm of ovary	Neoplasms; Female Urogenital Diseases and Pregnancy Complications; Endocrine System Diseases
C1168401	BXGD011792	Squamous cell carcinoma of the head and neck	Neoplasms
C1261473	BXGD011855	Sarcoma	Neoplasms
C1301937	BXGD012300	Talipes	Congenital, Hereditary, and Neonatal Diseases and Abnormalities; Musculoskeletal Diseases
C1306459	BXGD012361	Primary malignant neoplasm	Neoplasms
C1306460	BXGD012362	Primary malignant neoplasm of lung	Neoplasms; Respiratory Tract Diseases
C1328440	BXGD012466	Abnormality of amino acid metabolism
C1332206	BXGD012504	Adult Lymphoma	Neoplasms; Immune System Diseases; Hemic and Lymphatic Diseases
C1332977	BXGD012569	Childhood Leukemia	Neoplasms
C1332979	BXGD012571	Childhood Lymphoma	Neoplasms; Immune System Diseases; Hemic and Lymphatic Diseases
C1332986	BXGD012574	Childhood Osteosarcoma	Neoplasms
C1333762	BXGD012639	Gastric Cardia Adenocarcinoma
C1336527	BXGD012847	Carcinoma of urinary bladder, superficial	Neoplasms; Female Urogenital Diseases and Pregnancy Complications; Male Urogenital Diseases
C1337013	BXGD012876	Differentiated Thyroid Gland Carcinoma
C1384666	BXGD012948	hearing impairment	Pathological Conditions, Signs and Symptoms; Nervous System Diseases; Otorhinolaryngologic Diseases
C1833561	BXGD013934	UV-Sensitive Syndrome	Skin and Connective Tissue Diseases
C1836735	BXGD014155	hypopigmented skin patch	Skin and Connective Tissue Diseases
C1836830	BXGD014165	Developmental regression	Mental Disorders
C1837397	BXGD014227	Severe global developmental delay
C1842581	BXGD014525	Abnormal corpus callosum morphology	Pathological Conditions, Signs and Symptoms
C1842774	BXGD014536	Hypermelanotic macule
C1846149	BXGD014786	Intellectual disability, progressive	Pathological Conditions, Signs and Symptoms; Nervous System Diseases; Mental Disorders; Behavior and Behavior Mechanisms
C1849367	BXGD015046	Nasal bridge wide
C1851443	BXGD015215	Cerebrooculofacioskeletal Syndrome 3	Congenital, Hereditary, and Neonatal Diseases and Abnormalities; Nutritional and Metabolic Diseases; Musculoskeletal Diseases; Nervous System Diseases
C1853246	BXGD015323	Eversion of lower lip
C1857656	BXGD015731	Prematurely aged appearance
C1857949	BXGD015758	Prominent metopic ridge
C1858430	BXGD015792	Death in infancy
C1859312	BXGD015873	CAMFAK syndrome	Pathological Conditions, Signs and Symptoms; Congenital, Hereditary, and Neonatal Diseases and Abnormalities; Eye Diseases; Musculoskeletal Diseases; Nervous System Diseases
C1861403	BXGD016045	Variable expressivity
C1862475	BXGD016132	Abnormality of retinal pigmentation
C1866934	BXGD016427	Reduced tendon reflexes	Pathological Conditions, Signs and Symptoms; Nervous System Diseases
C1868085	BXGD016486	Craniofacial hyperostosis
C1956346	BXGD016627	Coronary Artery Disease	Cardiovascular Diseases
C1962966	BXGD016678	Retinopathy, CTCAE
C1963094	BXGD016681	Dry Skin, CTCAE
C1963184	BXGD016688	Nystagmus, CTCAE 3.0
C1968561	BXGD016713	Xeroderma Pigmentosum, Type G-Cockayne Syndrome	Congenital, Hereditary, and Neonatal Diseases and Abnormalities; Neoplasms; Nutritional and Metabolic Diseases; Skin and Connective Tissue Diseases; Musculoskeletal Diseases; Nervous System Diseases
C1968564	BXGD016714	Defective DNA repair after ultraviolet radiation damage
C1968565	BXGD016715	Numerous pigmented freckles
C2239176	BXGD016965	Liver carcinoma	Digestive System Diseases; Neoplasms
C2674608	BXGD017250	Feeding difficulties in infancy
C2717836	BXGD017510	Steroid Sulfatase Deficiency Disease	Congenital, Hereditary, and Neonatal Diseases and Abnormalities; Nutritional and Metabolic Diseases; Skin and Connective Tissue Diseases
C2752147	BXGD017769	XERODERMA PIGMENTOSUM, COMPLEMENTATION GROUP C	Congenital, Hereditary, and Neonatal Diseases and Abnormalities; Neoplasms; Nutritional and Metabolic Diseases; Skin and Connective Tissue Diseases
C2919142	BXGD017867	Short Stature, CTCAE
C2931277	BXGD017995	Pena Shokeir syndrome Type 2	Congenital, Hereditary, and Neonatal Diseases and Abnormalities; Eye Diseases
C2939419	BXGD018178	Secondary Neoplasm	Pathological Conditions, Signs and Symptoms; Neoplasms
C3279222	BXGD018751	Aplasia/Hypoplasia of the cerebellum
C3469521	BXGD018910	FANCONI ANEMIA, COMPLEMENTATION GROUP A (disorder)	Congenital, Hereditary, and Neonatal Diseases and Abnormalities; Nutritional and Metabolic Diseases; Hemic and Lymphatic Diseases
C3665347	BXGD019279	Visual Impairment	Pathological Conditions, Signs and Symptoms; Eye Diseases; Nervous System Diseases
C3714756	BXGD019429	Intellectual Disability	Pathological Conditions, Signs and Symptoms; Nervous System Diseases; Mental Disorders; Behavior and Behavior Mechanisms
C3887461	BXGD019876	Head and Neck Carcinoma	Neoplasms
C4022018	BXGD020872	Telangiectasia of the skin	Cardiovascular Diseases
C4023616	BXGD021229	Abnormality of immune system physiology
C4023759	BXGD021259	Flat nasal alae
C4025252	BXGD021607	Abnormal nasal morphology
C4048328	BXGD021903	cervical cancer	Neoplasms; Female Urogenital Diseases and Pregnancy Complications
C4086165	BXGD022126	Childhood Neuroblastoma	Neoplasms
C4304411	BXGD022575	Xeroderma pigmentosum and Cockayne syndrome complex	Congenital, Hereditary, and Neonatal Diseases and Abnormalities; Neoplasms; Nutritional and Metabolic Diseases; Skin and Connective Tissue Diseases; Musculoskeletal Diseases; Nervous System Diseases
C4551583	BXGD023361	Cerebral cortical atrophy
C4551686	BXGD023391	Malignant neoplasm of soft tissue	Neoplasms
C4553743	BXGD023548	Spasticity, CTCAE
C4553962	BXGD023553	Hyperkeratosis, CTCAE
C4554036	BXGD023557	Nystagmus, CTCAE 5.0
C4721453	BXGD023744	Peripheral Nervous System Diseases	Nervous System Diseases
C4721610	BXGD023760	Carcinoma, Ovarian Epithelial	Neoplasms; Female Urogenital Diseases and Pregnancy Complications; Endocrine System Diseases
C4721806	BXGD023772	Carcinoma, Basal Cell	Neoplasms
C4722085	BXGD023788	Malignant neoplasm of colon and/or rectum

Target protein-related compounds

Compounds

BXGC Id	Compound Name	Strcuture	Molecular Weight
BXGC0000436	Glycerol		92.09

The target protein-related foods

Foods

BXGF Id	Food Name	Scientific Name	Food Group	Number of compound^{? Number of compound in food, higher numbers indicate the food are more associated with the protein}