Showing entry for Calcium-activated potassium channel subunit beta-4


　 　 　 　 　 　 　 　 　 　 　 　
General Target Information
BXGT IdBXGT025779
Protein NameCalcium-activated potassium channel subunit beta-4
Uniport IdQ86W47
GeneKCNMB4
Gene Id27345
DomainCaKB
Pfam PF03185  
OrganismHomo sapiens (Human)
Target protein  affiliated  biological  pathways
KEGG
Class Subclass KEGG Id Pathway Name
3. Environmental Information Processing 3.2 Signal transduction hsa04022 cGMP-PKG signaling pathway
5. Organismal Systems 5.3 Circulatory system hsa04270 Vascular smooth muscle contraction
5. Organismal Systems 5.2 Endocrine system hsa04911 Insulin secretion
Gene Ontology
GO Type GO Id Gene Ontology
Biological Process GO:0001508 action potential
Biological Process GO:0007268 chemical synaptic transmission
Biological Process GO:0005513 detection of calcium ion
Biological Process GO:0019228 neuronal action potential
Biological Process GO:0006813 potassium ion transport
Biological Process GO:0046928 regulation of neurotransmitter secretion
Biological Process GO:0019229 regulation of vasoconstriction
molecular function GO:0015269 calcium-activated potassium channel activity
molecular function GO:0015459 potassium channel regulator activity
cellular component GO:0005887 integral component of plasma membrane
cellular component GO:0005886 plasma membrane
cellular component GO:0045202 synapse
cellular component GO:0008076 voltage-gated potassium channel complex
Reactome
Pathway Id Pathway Name
R-HSA-109582 Hemostasis
R-HSA-112316 Neuronal System
R-HSA-1296052 Ca2+ activated K+ channels
R-HSA-1296071 Potassium Channels
R-HSA-392154 Nitric oxide stimulates guanylate cyclase
R-HSA-418346 Platelet homeostasis
R-HSA-418457 cGMP effects
Target protein-related  diseases
Disease
CUI Id BXGD Id Disease Name Disease Class
C0005890 BXGD000345 Body Height
C0014556 BXGD000932 Epilepsy, Temporal Lobe Nervous System Diseases
C0027651 BXGD002009 Neoplasms Neoplasms
C0029463 BXGD002160 Osteosarcoma Neoplasms
C0036572 BXGD002625 Seizures Pathological Conditions, Signs and Symptoms; Nervous System Diseases
C0585442 BXGD009593 Osteosarcoma of bone Neoplasms
C1332986 BXGD012574 Childhood Osteosarcoma Neoplasms
Target protein-related  compounds
Compounds
BXGC Id Compound Name Strcuture Molecular Weight
BXGC0038316 Cholesterol 386.35
The  target protein-related  foods
Foods
BXGF Id Food Name Scientific Name Food Group Number of compound? Number of compound in food, higher numbers indicate the food are more associated with the protein