Showing entry for NPC1-like intracellular cholesterol transporter 1


　 　 　 　 　 　 　 　 　 　 　 　
General Target Information
BXGT IdBXGT025780
Protein NameNPC1-like intracellular cholesterol transporter 1
Uniport IdQ6T3U3
GeneNpc1l1
Gene Id432367
DomainNPC1_N; Patched; Sterol-sensing
Pfam PF16414   PF02460   PF12349  
OrganismRattus norvegicus (Rat)
Target protein  affiliated  biological  pathways
KEGG
Class Subclass KEGG Id Pathway Name
Gene Ontology
GO Type GO Id Gene Ontology
Biological Process GO:0071501 cellular response to sterol depletion
Biological Process GO:0006695 cholesterol biosynthetic process
Biological Process GO:0042632 cholesterol homeostasis
Biological Process GO:0030301 cholesterol transport
Biological Process GO:0030299 intestinal cholesterol absorption
Biological Process GO:0042157 lipoprotein metabolic process
Biological Process GO:0042493 response to drug
Biological Process GO:0014850 response to muscle activity
molecular function GO:0008144 drug binding
molecular function GO:0005319 lipid transporter activity
molecular function GO:0031489 myosin V binding
molecular function GO:0017137 Rab GTPase binding
cellular component GO:0016324 apical plasma membrane
cellular component GO:0031526 brush border membrane
cellular component GO:0044214 spanning component of plasma membrane
Reactome
Pathway Id Pathway Name
Target protein-related  diseases
Disease
CUI Id BXGD Id Disease Name Disease Class
Target protein-related  compounds
Compounds
BXGC Id Compound Name Strcuture Molecular Weight
BXGC0038316 Cholesterol 386.35
The  target protein-related  foods
Foods
BXGF Id Food Name Scientific Name Food Group Number of compound? Number of compound in food, higher numbers indicate the food are more associated with the protein