Showing entry for Importin-5


　 　 　 　 　 　 　 　 　 　 　 　
General Target Information
BXGT IdBXGT025968
Protein NameImportin-5
Uniport IdO00410
GeneIPO5
Gene Id3843
DomainHEAT; Importin_rep_4; Importin_rep_6
Pfam PF02985   PF18808   PF18829  
OrganismHomo sapiens (Human)
Target protein  affiliated  biological  pathways
KEGG
Class Subclass KEGG Id Pathway Name
Gene Ontology
GO Type GO Id Gene Ontology
Biological Process GO:0071230 cellular response to amino acid stimulus
Biological Process GO:0045736 negative regulation of cyclin-dependent protein serine/threonine kinase activity
Biological Process GO:0006607 NLS-bearing protein import into nucleus
Biological Process GO:0042307 positive regulation of protein import into nucleus
Biological Process GO:0006606 protein import into nucleus
Biological Process GO:0006610 ribosomal protein import into nucleus
Biological Process GO:0016032 viral process
molecular function GO:0005095 GTPase inhibitor activity
molecular function GO:0061608 nuclear import signal receptor activity
molecular function GO:0008139 nuclear localization sequence binding
molecular function GO:0008536 Ran GTPase binding
molecular function GO:0003723 RNA binding
cellular component GO:0005737 cytoplasm
cellular component GO:0016020 membrane
cellular component GO:0005643 nuclear pore
cellular component GO:0005730 nucleolus
cellular component GO:0005634 nucleus
Reactome
Pathway Id Pathway Name
R-HSA-1643685 Disease
R-HSA-168255 Influenza Infection
R-HSA-168273 Influenza Viral RNA Transcription and Replication
R-HSA-192905 vRNP Assembly
R-HSA-5663205 Infectious disease
Target protein-related  diseases
Disease
CUI Id BXGD Id Disease Name Disease Class
C0009402 BXGD000605 Colorectal Carcinoma Digestive System Diseases; Neoplasms
C0021400 BXGD001504 Influenza Infections; Respiratory Tract Diseases
C0022578 BXGD001557 Keratoconus Eye Diseases
C0036341 BXGD002600 Schizophrenia Mental Disorders
C0152013 BXGD003516 Adenocarcinoma of lung (disorder) Neoplasms
C0178874 BXGD004037 Tumor Progression Pathological Conditions, Signs and Symptoms
C1704436 BXGD013564 Peripheral Arterial Diseases Cardiovascular Diseases
C2062441 BXGD016897 Influenza A
C4722085 BXGD023788 Malignant neoplasm of colon and/or rectum
Target protein-related  compounds
Compounds
BXGC Id Compound Name Strcuture Molecular Weight
BXGC0003705 Chloride 35.45
The  target protein-related  foods
Foods
BXGF Id Food Name Scientific Name Food Group Number of compound? Number of compound in food, higher numbers indicate the food are more associated with the protein