Showing entry for Protein DBF4 homolog A


　 　 　 　 　 　 　 　 　 　 　 　
General Target Information
BXGT IdBXGT025998
Protein NameProtein DBF4 homolog A
Uniport IdQ9UBU7
GeneDBF4
Gene Id10926
Domainzf-DBF
Pfam PF07535  
OrganismHomo sapiens (Human)
Target protein  affiliated  biological  pathways
KEGG
Class Subclass KEGG Id Pathway Name
4. Cellular Processes 4.2 Cell growth and death hsa04110 Cell cycle
Gene Ontology
GO Type GO Id Gene Ontology
Biological Process GO:0006260 DNA replication
Biological Process GO:0000082 G1/S transition of mitotic cell cycle
Biological Process GO:0010571 positive regulation of nuclear cell cycle DNA replication
Biological Process GO:1901987 regulation of cell cycle phase transition
molecular function GO:0008047 enzyme activator activity
molecular function GO:0003676 nucleic acid binding
molecular function GO:0043539 protein serine/threonine kinase activator activity
molecular function GO:0008270 zinc ion binding
cellular component GO:0031431 Dbf4-dependent protein kinase complex
cellular component GO:0016604 nuclear body
cellular component GO:0005654 nucleoplasm
cellular component GO:0005634 nucleus
Reactome
Pathway Id Pathway Name
R-HSA-1640170 Cell Cycle
R-HSA-176187 Activation of ATR in response to replication stress
R-HSA-453279 Mitotic G1 phase and G1/S transition
R-HSA-68962 Activation of the pre-replicative complex
R-HSA-69002 DNA Replication Pre-Initiation
R-HSA-69206 G1/S Transition
R-HSA-69278 Cell Cycle, Mitotic
R-HSA-69306 DNA Replication
R-HSA-69481 G2/M Checkpoints
R-HSA-69620 Cell Cycle Checkpoints
Target protein-related  diseases
Disease
CUI Id BXGD Id Disease Name Disease Class
C0006826 BXGD000408 Malignant Neoplasms Neoplasms
C0025202 BXGD001832 melanoma Neoplasms
C0027651 BXGD002009 Neoplasms Neoplasms
C0151779 BXGD003473 Cutaneous Melanoma Neoplasms; Skin and Connective Tissue Diseases
C0153252 BXGD003616 Systemic candidiasis Infections
C0596263 BXGD009639 Carcinogenesis Pathological Conditions, Signs and Symptoms; Neoplasms
C0877445 BXGD011350 Candidemia Pathological Conditions, Signs and Symptoms; Infections
C1262313 BXGD011881 Invasive Fungal Infections Infections
C1306459 BXGD012361 Primary malignant neoplasm Neoplasms
C1609535 BXGD013443 Invasive Candidiasis Infections
Target protein-related  compounds
Compounds
BXGC Id Compound Name Strcuture Molecular Weight
BXGC0003705 Chloride 35.45
The  target protein-related  foods
Foods
BXGF Id Food Name Scientific Name Food Group Number of compound? Number of compound in food, higher numbers indicate the food are more associated with the protein