Showing entry for Sphingomyelin phosphodiesterase


　 　 　 　 　 　 　 　 　 　 　 　
General Target Information
BXGT IdBXGT026117
Protein NameSphingomyelin phosphodiesterase
Uniport IdQ0VD19
GeneSMPD1
Gene Id505097
DomainMetallophos
Pfam PF00149  
OrganismBos taurus (Bovine)
Target protein  affiliated  biological  pathways
KEGG
Class Subclass KEGG Id Pathway Name
Gene Ontology
GO Type GO Id Gene Ontology
Biological Process GO:0046513 ceramide biosynthetic process
Biological Process GO:0008203 cholesterol metabolic process
Biological Process GO:0043407 negative regulation of MAP kinase activity
Biological Process GO:0035307 positive regulation of protein dephosphorylation
Biological Process GO:0006685 sphingomyelin catabolic process
Biological Process GO:0023021 termination of signal transduction
molecular function GO:0061750 acid sphingomyelin phosphodiesterase activity
molecular function GO:0016798 hydrolase activity, acting on glycosyl bonds
molecular function GO:0008081 phosphoric diester hydrolase activity
molecular function GO:0004767 sphingomyelin phosphodiesterase activity
molecular function GO:0008270 zinc ion binding
cellular component GO:0005768 endosome
cellular component GO:0005615 extracellular space
cellular component GO:0005765 lysosomal membrane
cellular component GO:0005764 lysosome
cellular component GO:0045121 membrane raft
cellular component GO:0005886 plasma membrane
Reactome
Pathway Id Pathway Name
Target protein-related  diseases
Disease
CUI Id BXGD Id Disease Name Disease Class
Target protein-related  compounds
Compounds
BXGC Id Compound Name Strcuture Molecular Weight
BXGC0007560 alpha-Mangostin 410.46
The  target protein-related  foods
Foods
BXGF Id Food Name Scientific Name Food Group Number of compound? Number of compound in food, higher numbers indicate the food are more associated with the protein