Showing entry for Tyrosine-protein kinase JAK1



                       
General Target Information
BXGT IdBXGT026121
Protein NameTyrosine-protein kinase JAK1
Uniport IdP52332
GeneJak1
Gene Id
DomainFERM_F1; FERM_F2; Jak1_Phl; Pkinase_Tyr
Pfam PF18379   PF18377   PF17887   PF07714  
OrganismMus musculus (Mouse)
Target protein  affiliated  biological  pathways
KEGG
Class Subclass KEGG Id Pathway Name
Gene Ontology
GO Type GO Id Gene Ontology
Biological Process GO:0036016 cellular response to interleukin-3
Biological Process GO:0098761 cellular response to interleukin-7
Biological Process GO:0019221 cytokine-mediated signaling pathway
Biological Process GO:0007167 enzyme linked receptor protein signaling pathway
Biological Process GO:0038110 interleukin-2-mediated signaling pathway
Biological Process GO:0035556 intracellular signal transduction
Biological Process GO:0018108 peptidyl-tyrosine phosphorylation
Biological Process GO:0034112 positive regulation of homotypic cell-cell adhesion
Biological Process GO:1904894 positive regulation of receptor signaling pathway via STAT
Biological Process GO:1903672 positive regulation of sprouting angiogenesis
Biological Process GO:0150105 protein localization to cell-cell junction
Biological Process GO:0046677 response to antibiotic
Biological Process GO:0007260 tyrosine phosphorylation of STAT protein
molecular function GO:0005524 ATP binding
molecular function GO:0031730 CCR5 chemokine receptor binding
molecular function GO:0005131 growth hormone receptor binding
molecular function GO:0046872 metal ion binding
molecular function GO:0004715 non-membrane spanning protein tyrosine kinase activity
molecular function GO:0019903 protein phosphatase binding
molecular function GO:0004713 protein tyrosine kinase activity
molecular function GO:0031625 ubiquitin protein ligase binding
cellular component GO:0005737 cytoplasm
cellular component GO:0005856 cytoskeleton
cellular component GO:0005829 cytosol
cellular component GO:0012505 endomembrane system
cellular component GO:0016020 membrane
cellular component GO:0005634 nucleus
Reactome
Pathway Id Pathway Name
Target protein-related  diseases
Disease
CUI Id BXGD Id Disease Name Disease Class
Target protein-related  compounds
Compounds
BXGC Id Compound Name Strcuture Molecular Weight
BXGC0004866 Nb-trans-Feruloylserotonin 352.38
The  target protein-related  foods
Foods
BXGF Id Food Name Scientific Name Food Group Number of compound? Number of compound in food, higher numbers indicate the food are more associated with the protein