Showing entry for P2X purinoceptor 7


　 　 　 　 　 　 　 　 　 　 　 　
General Target Information
BXGT IdBXGT026123
Protein NameP2X purinoceptor 7
Uniport IdQ9Z1M0
GeneP2rx7
Gene Id18439
DomainP2X_receptor
Pfam -  
OrganismMus musculus (Mouse)
Target protein  affiliated  biological  pathways
KEGG
Class Subclass KEGG Id Pathway Name
Gene Ontology
GO Type GO Id Gene Ontology
Biological Process GO:0000187 activation of MAPK activity
Biological Process GO:0032060 bleb assembly
Biological Process GO:0006816 calcium ion transport
Biological Process GO:0006812 cation transport
Biological Process GO:0008219 cell death
Biological Process GO:0000902 cell morphogenesis
Biological Process GO:0071359 cellular response to dsRNA
Biological Process GO:0031668 cellular response to extracellular stimulus
Biological Process GO:0071407 cellular response to organic cyclic compound
Biological Process GO:0006884 cell volume homeostasis
Biological Process GO:0046513 ceramide biosynthetic process
Biological Process GO:0032963 collagen metabolic process
Biological Process GO:0050830 defense response to Gram-positive bacterium
Biological Process GO:0097191 extrinsic apoptotic signaling pathway
Biological Process GO:0010467 gene expression
Biological Process GO:0048873 homeostasis of number of cells within a tissue
Biological Process GO:0006954 inflammatory response
Biological Process GO:0051899 membrane depolarization
Biological Process GO:0006509 membrane protein ectodomain proteolysis
Biological Process GO:0007005 mitochondrion organization
Biological Process GO:0043132 NAD transport
Biological Process GO:0045779 negative regulation of bone resorption
Biological Process GO:0045794 negative regulation of cell volume
Biological Process GO:0043409 negative regulation of MAPK cascade
Biological Process GO:0001845 phagolysosome assembly
Biological Process GO:0006649 phospholipid transfer to membrane
Biological Process GO:0045332 phospholipid translocation
Biological Process GO:0007009 plasma membrane organization
Biological Process GO:0017121 plasma membrane phospholipid scrambling
Biological Process GO:0046931 pore complex assembly
Biological Process GO:0043065 positive regulation of apoptotic process
Biological Process GO:1904172 positive regulation of bleb assembly
Biological Process GO:0030501 positive regulation of bone mineralization
Biological Process GO:0010524 positive regulation of calcium ion transport into cytosol
Biological Process GO:0043085 positive regulation of catalytic activity
Biological Process GO:0050715 positive regulation of cytokine secretion
Biological Process GO:0014054 positive regulation of gamma-aminobutyric acid secretion
Biological Process GO:0010628 positive regulation of gene expression
Biological Process GO:0014049 positive regulation of glutamate secretion
Biological Process GO:0045821 positive regulation of glycolytic process
Biological Process GO:0032730 positive regulation of interleukin-1 alpha production
Biological Process GO:0032731 positive regulation of interleukin-1 beta production
Biological Process GO:0032755 positive regulation of interleukin-6 production
Biological Process GO:0034767 positive regulation of ion transmembrane transport
Biological Process GO:0070230 positive regulation of lymphocyte apoptotic process
Biological Process GO:0043410 positive regulation of MAPK cascade
Biological Process GO:0051901 positive regulation of mitochondrial depolarization
Biological Process GO:0045778 positive regulation of ossification
Biological Process GO:0032308 positive regulation of prostaglandin secretion
Biological Process GO:0001934 positive regulation of protein phosphorylation
Biological Process GO:0050714 positive regulation of protein secretion
Biological Process GO:0001916 positive regulation of T cell mediated cytotoxicity
Biological Process GO:0012501 programmed cell death
Biological Process GO:0030163 protein catabolic process
Biological Process GO:0006468 protein phosphorylation
Biological Process GO:0016485 protein processing
Biological Process GO:0035590 purinergic nucleotide receptor signaling pathway
Biological Process GO:0072593 reactive oxygen species metabolic process
Biological Process GO:0051209 release of sequestered calcium ion into cytosol
Biological Process GO:0033198 response to ATP
Biological Process GO:0009617 response to bacterium
Biological Process GO:0051592 response to calcium ion
Biological Process GO:0042493 response to drug
Biological Process GO:0051602 response to electrical stimulus
Biological Process GO:0034405 response to fluid shear stress
Biological Process GO:0032496 response to lipopolysaccharide
Biological Process GO:0009612 response to mechanical stimulus
Biological Process GO:0014070 response to organic cyclic compound
Biological Process GO:0010033 response to organic substance
Biological Process GO:0010043 response to zinc ion
Biological Process GO:0019233 sensory perception of pain
Biological Process GO:0048705 skeletal system morphogenesis
Biological Process GO:0016079 synaptic vesicle exocytosis
Biological Process GO:0043029 T cell homeostasis
Biological Process GO:0042098 T cell proliferation
Biological Process GO:0006900 vesicle budding from membrane
molecular function GO:0005524 ATP binding
molecular function GO:0015267 channel activity
molecular function GO:0004931 extracellularly ATP-gated cation channel activity
molecular function GO:0042802 identical protein binding
molecular function GO:0001530 lipopolysaccharide binding
molecular function GO:0001614 purinergic nucleotide receptor activity
molecular function GO:0038023 signaling receptor activity
cellular component GO:0005911 cell-cell junction
cellular component GO:0009897 external side of plasma membrane
cellular component GO:0005639 integral component of nuclear inner membrane
cellular component GO:0005887 integral component of plasma membrane
cellular component GO:0016020 membrane
cellular component GO:0031594 neuromuscular junction
cellular component GO:0043025 neuronal cell body
cellular component GO:0005886 plasma membrane
cellular component GO:0098794 postsynapse
cellular component GO:0098793 presynapse
cellular component GO:0045202 synapse
Reactome
Pathway Id Pathway Name
Target protein-related  diseases
Disease
CUI Id BXGD Id Disease Name Disease Class
Target protein-related  compounds
Compounds
BXGC Id Compound Name Strcuture Molecular Weight
BXGC0020024 Lawsone 174.03
The  target protein-related  foods
Foods
BXGF Id Food Name Scientific Name Food Group Number of compound? Number of compound in food, higher numbers indicate the food are more associated with the protein