Showing entry for Sarcoplasmic/endoplasmic reticulum calcium ATPase 2


　 　 　 　 　 　 　 　 　 　 　 　
General Target Information
BXGT IdBXGT026176
Protein NameSarcoplasmic/endoplasmic reticulum calcium ATPase 2
Uniport IdP11507
GeneAtp2a2
Gene Id29693
DomainCation_ATPase; Cation_ATPase_C; Cation_ATPase_N; E1-E2_ATPase
Pfam PF00689   PF00690  
OrganismRattus norvegicus (Rat)
Target protein  affiliated  biological  pathways
KEGG
Class Subclass KEGG Id Pathway Name
Gene Ontology
GO Type GO Id Gene Ontology
Biological Process GO:1990036 calcium ion import into sarcoplasmic reticulum
Biological Process GO:0070588 calcium ion transmembrane transport
Biological Process GO:0006816 calcium ion transport
Biological Process GO:1903515 calcium ion transport from cytosol to endoplasmic reticulum
Biological Process GO:0014898 cardiac muscle hypertrophy in response to stress
Biological Process GO:0006874 cellular calcium ion homeostasis
Biological Process GO:0034605 cellular response to heat
Biological Process GO:0034599 cellular response to oxidative stress
Biological Process GO:0032469 endoplasmic reticulum calcium ion homeostasis
Biological Process GO:0006984 ER-nucleus signaling pathway
Biological Process GO:0045822 negative regulation of heart contraction
Biological Process GO:1900121 negative regulation of receptor binding
Biological Process GO:0006996 organelle organization
Biological Process GO:0032470 positive regulation of endoplasmic reticulum calcium ion concentration
Biological Process GO:1903233 regulation of calcium ion-dependent exocytosis of neurotransmitter
Biological Process GO:0098909 regulation of cardiac muscle cell action potential involved in regulation of contraction
Biological Process GO:0086036 regulation of cardiac muscle cell membrane potential
Biological Process GO:0010882 regulation of cardiac muscle contraction by calcium ion signaling
Biological Process GO:0006937 regulation of muscle contraction
Biological Process GO:0002026 regulation of the force of heart contraction
Biological Process GO:0055119 relaxation of cardiac muscle
Biological Process GO:0034976 response to endoplasmic reticulum stress
Biological Process GO:0032496 response to lipopolysaccharide
Biological Process GO:0043434 response to peptide hormone
Biological Process GO:0070296 sarcoplasmic reticulum calcium ion transport
Biological Process GO:0003009 skeletal muscle contraction
Biological Process GO:0014883 transition between fast and slow fiber
Biological Process GO:0033292 T-tubule organization
molecular function GO:0016887 ATPase activity
molecular function GO:0005524 ATP binding
molecular function GO:0005509 calcium ion binding
molecular function GO:0005388 calcium transmembrane transporter activity, phosphorylative mechanism
molecular function GO:0086039 calcium-transporting ATPase activity involved in regulation of cardiac muscle cell membrane potential
molecular function GO:0019899 enzyme binding
molecular function GO:0044325 ion channel binding
molecular function GO:0031775 lutropin-choriogonadotropic hormone receptor binding
molecular function GO:0008022 protein C-terminus binding
molecular function GO:0008553 proton-exporting ATPase activity, phosphorylative mechanism
molecular function GO:0044548 S100 protein binding
cellular component GO:0061831 apical ectoplasmic specialization
cellular component GO:0090534 calcium ion-transporting ATPase complex
cellular component GO:0005783 endoplasmic reticulum
cellular component GO:0005789 endoplasmic reticulum membrane
cellular component GO:0031234 extrinsic component of cytoplasmic side of plasma membrane
cellular component GO:0014801 longitudinal sarcoplasmic reticulum
cellular component GO:0016020 membrane
cellular component GO:0048471 perinuclear region of cytoplasm
cellular component GO:0120025 plasma membrane bounded cell projection
cellular component GO:0032991 protein-containing complex
cellular component GO:0097470 ribbon synapse
cellular component GO:0016529 sarcoplasmic reticulum
cellular component GO:0033017 sarcoplasmic reticulum membrane
cellular component GO:0012506 vesicle membrane
Reactome
Pathway Id Pathway Name
Target protein-related  diseases
Disease
CUI Id BXGD Id Disease Name Disease Class
Target protein-related  compounds
Compounds
BXGC Id Compound Name Strcuture Molecular Weight
BXGC0023873 Ivermectin 874.51
The  target protein-related  foods
Foods
BXGF Id Food Name Scientific Name Food Group Number of compound? Number of compound in food, higher numbers indicate the food are more associated with the protein