P49336	CDK8 

                    

                     
                        Group: CMGC
Family: CDK
PDB Structure Num: 24
 
                    

                    


                    
                    
                    
                    



                    

                    

                        
                            

                                structure
                                        FDA kinase druginchikeydata countactive numinactive numsame percentagevote label                            

                        
                        
                        
                            
                            
                            
ZKGWDQMQMQRGLJ-UHFFFAOYSA-N43175%exclude
DDMBDFURJHEOSG-UHFFFAOYSA-N101100%inactive
IIIQUEYXCDAEGD-UHFFFAOYSA-N110100%active
WVZGDHXIWUSKHK-UHFFFAOYSA-N110100%active
BGVLCUOYRCTJCU-UHFFFAOYSA-N101100%inactive
FGWWXXXOMYTMPD-UHFFFAOYSA-N110100%active
KBXKPZZOWBAGTC-UHFFFAOYSA-N101100%inactive
WWSYRAJTUUAHEC-UHFFFAOYSA-N110100%active
GPXUGZJCRBUYGZ-INIZCTEOSA-N110100%active
LJDCQQGXLNPEAO-UHFFFAOYSA-N110100%active
ZGPVOHOOXZLRKY-UHFFFAOYSA-N110100%active
APIRNJQTJSYXTA-UHFFFAOYSA-N110100%active
MUKGYZFIZLFCGL-LJQANCHMSA-N110100%active
MUKGYZFIZLFCGL-IBGZPJMESA-N110100%active
GEANABGVEPQZHT-UHFFFAOYSA-N110100%active
OMIZKYBIVWGYBC-UHFFFAOYSA-N110100%active
ZWTOETHVOACJIW-UHFFFAOYSA-N110100%active
LZRZCEHXAQZTIA-UHFFFAOYSA-N110100%active
OHNXBYACIOVGBQ-UHFFFAOYSA-N110100%active
DALLTCCRBXGGIY-UHFFFAOYSA-N110100%active
QZIQKCPFANRCTO-UHFFFAOYSA-N110100%active
LCUMHIHAYAXPDL-UHFFFAOYSA-N110100%active
QOHBWKYBTSWNGX-UHFFFAOYSA-N110100%active
CPFVIABLSKKULA-UHFFFAOYSA-N110100%active
MJZXLJIFSOYQOU-UHFFFAOYSA-N110100%active
UQRFZZAOVZWDSA-UHFFFAOYSA-N101100%inactive
JMTPOBLXKZZYCU-UHFFFAOYSA-N101100%inactive
HAMWSFRMPKMULI-UHFFFAOYSA-N110100%active
LBFYQISQYCGDDW-UHFFFAOYSA-N110100%active
HOFCDHUGGVZPCY-UHFFFAOYSA-N110100%active
RLVURTZJQZIODI-UHFFFAOYSA-N110100%active
PSLTXNZIRUGQOG-UHFFFAOYSA-N110100%active
UXSVDQPKNXQICD-UHFFFAOYSA-N110100%active
NALGKDPHSMQYFA-UHFFFAOYSA-N110100%active
RJZUGXNAXUOKRX-UHFFFAOYSA-N110100%active
SRMSEKPITZQWRD-UHFFFAOYSA-N110100%active
NCIRPZWSTPFOGW-UHFFFAOYSA-N110100%active
UBTVSFFSPMDFDG-UHFFFAOYSA-N101100%inactive
MLTSNXSYHSYGAM-UHFFFAOYSA-N110100%active
ZVSGCPGPQNLKLU-UHFFFAOYSA-N110100%active
QCGCKUCRBUABID-UHFFFAOYSA-N110100%active
AKRQDWCCIMBUAA-UHFFFAOYSA-N110100%active
MIELHCGANGLYOP-UHFFFAOYSA-N110100%active
AXGBNOWDDQXXDR-UHFFFAOYSA-N110100%active
ZFBNRSHAOSUFDF-UHFFFAOYSA-N110100%active
VPJXPDLMACOGIZ-UHFFFAOYSA-N110100%active
GHHDMQJYDMQTDY-UHFFFAOYSA-N110100%active
IZIZTVUBBXGCPR-UHFFFAOYSA-N110100%active
FZQAZSRDRZGHTP-UHFFFAOYSA-N110100%active
SIWAQIAXQNZGEJ-UHFFFAOYSA-N110100%active
OSUSJQOYNWQHEC-UHFFFAOYSA-N110100%active
ZLJBWVWHTDCWFO-UHFFFAOYSA-N110100%active
QLMIHYKKDODCRC-UHFFFAOYSA-N110100%active
KQBZMDCNLVOJPZ-UHFFFAOYSA-N101100%inactive
RDVHTWWUICGUOA-UHFFFAOYSA-N110100%active
GRKOQLWARQVTPO-UHFFFAOYSA-N110100%active
WLNUDRFOSHWBNG-UHFFFAOYSA-N110100%active
YWHDHVUZZPMSQD-UHFFFAOYSA-N110100%active
AKMUJHSPPZVLAJ-UHFFFAOYSA-N110100%active
LAYMXNJSUDFINH-UHFFFAOYSA-N110100%active
GBYCDBFSAXCWDG-UHFFFAOYSA-N110100%active
UYMBYVWSBPECIF-UHFFFAOYSA-N110100%active
DMIAAAUSYPPGHE-UHFFFAOYSA-N110100%active
BRXPEZGPMOEOCA-UHFFFAOYSA-N110100%active
GQWMRZZYHJLZFL-UHFFFAOYSA-N110100%active
ZNMSRFYDOSAZLZ-UHFFFAOYSA-N110100%active
YQYMAYUQUXDUNP-UHFFFAOYSA-N110100%active
CGELUDGKNGUGSC-UHFFFAOYSA-N110100%active
LLNFBSQVFXOHIC-UHFFFAOYSA-N110100%active
SOGOUJPVOZWDFQ-UHFFFAOYSA-N110100%active
ORKBDPRQJKIQTC-UHFFFAOYSA-N110100%active
UWTMXZFDTBHJPH-UHFFFAOYSA-N110100%active
OMUNPUZBDSTLJV-UHFFFAOYSA-N110100%active
CPYTXFOZVKULHY-UHFFFAOYSA-N110100%active
MMTZCTUXVCJRSF-UHFFFAOYSA-N110100%active
NAVWVDFKHIIIDK-UHFFFAOYSA-N110100%active
TYCOTTAYUVNCMS-UHFFFAOYSA-N110100%active
MOARLOGPIPTREO-UHFFFAOYSA-N110100%active
GCMACTQBSNIQGT-UHFFFAOYSA-N110100%active
KBJXKLULHUAKPC-UHFFFAOYSA-N110100%active
AIOXFJJODLAAIZ-UHFFFAOYSA-N110100%active
KGLDQVUADAKWIL-UHFFFAOYSA-N110100%active
PZKWAHCUWGHBLH-MRXNPFEDSA-N101100%inactive
FBFCEASGGVTKEY-UHFFFAOYSA-N110100%active
BIPBLKIGJHZBND-UHFFFAOYSA-N110100%active
VWJSHXLEQJGMPN-UHFFFAOYSA-N110100%active
MOIRAYXVFLWFTA-UHFFFAOYSA-N110100%active
LMFQBGMZWYWWAV-UHFFFAOYSA-N110100%active
ALVRKNONSXJKLX-UHFFFAOYSA-N110100%active
VGQVYKSVLZIXPH-UHFFFAOYSA-N110100%active
OBXJXHURJISADY-UHFFFAOYSA-N110100%active
WBUMRDJBKJSRQP-UHFFFAOYSA-N101100%inactive
RMOAHCIFLAJLMD-UHFFFAOYSA-N110100%active
UEMDLSOAXRVEIR-UHFFFAOYSA-N110100%active
HAEDHIQEQOEOHP-UHFFFAOYSA-N110100%active
SLMBTUSZZKPYMQ-UHFFFAOYSA-N101100%inactive
NFDTYIAEGUXEIR-UHFFFAOYSA-N110100%active
YEOBHROCLHRPLB-UHFFFAOYSA-N110100%active
AGXNDPDCEGWAIY-UHFFFAOYSA-N110100%active
UBAGJSZELRSFGS-UHFFFAOYSA-N101100%inactive
QZSCJBLGVPAUTR-UHFFFAOYSA-N110100%active
DLRQNUMIROELBQ-UHFFFAOYSA-N101100%inactive
VYWUTAQQVFMHBW-UHFFFAOYSA-N110100%active
QDMGVWHKVHTJPB-UHFFFAOYSA-N110100%active
XOTPZBXWJPZQBY-UHFFFAOYSA-N110100%active
KDZLCWBDQVILHC-UHFFFAOYSA-N110100%active
IKNDNTIDNPFLAC-UHFFFAOYSA-N110100%active
XZWGYUDHWRFVLU-UHFFFAOYSA-N110100%active
WVPWJZVPSPEJCP-UHFFFAOYSA-N110100%active
RUNGUDNTFGOPRL-UHFFFAOYSA-N110100%active
RDJKDXOOXNKSCO-UHFFFAOYSA-N110100%active
QBMVSTFFMINBKY-UHFFFAOYSA-N110100%active
LOOFFGPDPOEAMT-UHFFFAOYSA-N110100%active
IBDRMDVDKFGXHV-UHFFFAOYSA-N110100%active
DJTZJKJIHWUBGI-UHFFFAOYSA-N110100%active
ZPRRYBVGWOTQNB-UHFFFAOYSA-N110100%active
SHRADRGUJPJGPF-UHFFFAOYSA-N110100%active
FXSAYAHGTCKXRP-UHFFFAOYSA-N110100%active
WJORYPIALAWPKB-UHFFFAOYSA-N110100%active
FBBJFNNZHXLBCQ-UHFFFAOYSA-N110100%active
ZLPZSHJTTWBCCD-UHFFFAOYSA-N110100%active
NUIUYBDMUVUCKC-UHFFFAOYSA-N110100%active
WGBUCZXTNTVPDM-UHFFFAOYSA-N110100%active
BEWMTAWSVCJGFE-UHFFFAOYSA-N101100%inactive
YXVVCWWWIWRJKH-UHFFFAOYSA-N110100%active
PKVBYJSJCFQYQW-UHFFFAOYSA-N110100%active
ZDHIDFYVFYJBJS-UHFFFAOYSA-N101100%inactive
ZFKIMLOZPZTQJP-UHFFFAOYSA-N110100%active
KPJPEYWXGRKBQF-UHFFFAOYSA-N110100%active
OJIQEAIHEGJBFE-UHFFFAOYSA-N110100%active
BWDARHFPTQIHIU-UHFFFAOYSA-N110100%active
PQCODRGUOJKOCC-UHFFFAOYSA-N110100%active
DFYVDBLGPYTIAT-UHFFFAOYSA-N110100%active
GTJWTPSHGINPNN-UHFFFAOYSA-N110100%active
BYWBSIVRCSZNJP-UHFFFAOYSA-N101100%inactive
CUQBBHUITNFLKO-KRWDZBQOSA-N110100%active
CQZLZZDJBYTSDH-UHFFFAOYSA-N110100%active
ODRITQGYYWHQGM-INIZCTEOSA-N550100%active
NYULWTAVHULAJK-UHFFFAOYSA-N110100%active
PAUXJRUOCRBJHR-INIZCTEOSA-N110100%active
FLEYJCJMMRLIBV-KRWDZBQOSA-N110100%active
HUMGDIWWCDUKKQ-KRWDZBQOSA-N110100%active
SAVNWXMDAMFANR-UHFFFAOYSA-N110100%active
SAVNWXMDAMFANR-ZDUSSCGKSA-N110100%active
VZPGERSMGVRRCU-UHFFFAOYSA-N110100%active
PEUOHMPBTLQKMK-INIZCTEOSA-N110100%active
JJIQBYGSBIHLSR-INIZCTEOSA-N110100%active
UBAOTUBXUAQBKH-SFHVURJKSA-N110100%active
VSIKBMSMNYEKJE-CYBMUJFWSA-N110100%active
QJIOPOJQZXHHEW-SFHVURJKSA-N110100%active
GHYABPDMZQFTSA-HNNXBMFYSA-N110100%active
QXNLDTWVURNIRW-KRWDZBQOSA-N110100%active
SAVNWXMDAMFANR-CYBMUJFWSA-N101100%inactive
QLSTWYIPABBKKG-UHFFFAOYSA-N110100%active
MEESYKZHJKDWJI-UHFFFAOYSA-N101100%inactive
ZOKLUCHKTUZIJY-INIZCTEOSA-N110100%active
VXYMGUGNDZARSZ-KRWDZBQOSA-N101100%inactive
FMTZJHHPYOHWNQ-UHFFFAOYSA-N101100%inactive
VZOLINZYKOLXAC-RBSFLKMASA-N110100%active
KSGZCKSNTAJOJS-DZBMUNJRSA-N110100%active
UETJKJCLDAZMNX-UHFFFAOYSA-N101100%inactive
SCCHIXXWAYEQDD-UHFFFAOYSA-N101100%inactive
DDLOAPULNRJWBM-UHFFFAOYSA-N101100%inactive
CISPMBXZQNYLKC-UHFFFAOYSA-N101100%inactive
UJIAQMCWYMQXCS-INIZCTEOSA-N101100%inactive
MDWXVGCLSBQVMP-UHFFFAOYSA-N101100%inactive
IGRYEDIMNMEBBU-UHFFFAOYSA-N101100%inactive
WHFIWINTCCNYQZ-UHFFFAOYSA-N101100%inactive