Q13546 RIPK1
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Group: TKL
Family: RIPK
PDB Structure Num: 11
FDA approved drugs from DrugBank: Fostamatinib
| structure | FDA kinase drug | inchikey | kinase profiling data count | kinase profiling label | ChEMBL data count | ChEMBL label | vote label |
|---|---|---|---|---|---|---|---|
 | BPNUQXPIQBZCMR-LJQANCHMSA-N | 1 | inactive | - | - | inactive | |
 | WJEOLQLKVOPQFV-UHFFFAOYSA-N | 1 | inactive | - | - | inactive | |
 | MPVGZUGXCQEXTM-UHFFFAOYSA-N | 1 | active | - | - | active | |
 | CVWXJKQAOSCOAB-UHFFFAOYSA-N | 1 | active | - | - | active | |
 | RITAVMQDGBJQJZ-UHFFFAOYSA-N | 1 | active | - | - | active | |
 | RAHBGWKEPAQNFF-UHFFFAOYSA-N | 1 | inactive | - | - | inactive | |
 | ODPGGGTTYSGTGO-UHFFFAOYSA-N | 1 | active | - | - | active | |
 | OVPNQJVDAFNBDN-UHFFFAOYSA-N | 1 | inactive | - | - | inactive | |
 | QYZOGCMHVIGURT-UHFFFAOYSA-N | 1 | inactive | - | - | inactive | |
 | XXJWYDDUDKYVKI-UHFFFAOYSA-N | 1 | inactive | - | - | inactive | |
 | CYOHGALHFOKKQC-UHFFFAOYSA-N | 1 | inactive | - | - | inactive | |
 | XQVVPGYIWAGRNI-QFIPXVFZSA-N | 1 | inactive | - | - | inactive | |
| - | FCLPVPNWFDOVKL-DQSJHHFOSA-N | 1 | active | - | - | active | |
 | ULXXDDBFHOBEHA-INIZCTEOSA-N | 1 | inactive | - | - | inactive | |
 | MVCOAUNKQVWQHZ-UHFFFAOYSA-N | 1 | inactive | - | - | inactive | |
 | PSPFQEBFYXJZEV-UHFFFAOYSA-N | 1 | inactive | - | - | inactive | |
 | OUSFTKFNBAZUKL-UHFFFAOYSA-N | 1 | inactive | - | - | inactive | |
 | WCWUXEGQKLTGDX-NSHDSACASA-N | 1 | inactive | - | - | inactive | |
 | UIARLYUEJFELEN-FMLDBKJISA-N | 1 | inactive | - | - | inactive | |
| - | KCOYQXZDFIIGCY-CZIZESTLSA-N | 1 | active | - | - | active | |
 | YABJJWZLRMPFSI-UHFFFAOYSA-N | 1 | inactive | - | - | inactive | |
 | OMZCMEYTWSXEPZ-UHFFFAOYSA-N | 1 | inactive | - | - | inactive | |
 | GFMMXOIFOQCCGU-UHFFFAOYSA-N | 1 | inactive | - | - | inactive | |
 | UJLAWZDWDVHWOW-DGCLKSJQSA-N | 1 | inactive | - | - | inactive | |
 | Crizotinib | KTEIFNKAUNYNJU-GFCCVEGCSA-N | 1 | active | - | - | active |
 | Dasatinib | ZBNZXTGUTAYRHI-UHFFFAOYSA-N | 1 | inactive | - | - | inactive |
 | Erlotinib | AAKJLRGGTJKAMG-UHFFFAOYSA-N | 1 | inactive | - | - | inactive |
 | CXQHYVUVSFXTMY-UHFFFAOYSA-N | 1 | active | - | - | active | |
 | BIIVYFLTOXDAOV-YVEFUNNKSA-N | 1 | inactive | - | - | inactive | |
 | DEZZLWQELQORIU-UHFFFAOYSA-N | 1 | inactive | - | - | inactive | |
 | LHNIIDJUOCFXAP-UHFFFAOYSA-N | 1 | inactive | - | - | inactive | |
 | Gefitinib | XGALLCVXEZPNRQ-UHFFFAOYSA-N | 1 | inactive | - | - | inactive |
| - | XWFUWIOJOVXAMS-FXIRQEPWSA-N | 1 | inactive | - | - | inactive | |
 | ZHJGWYRLJUCMRT-QGZVFWFLSA-N | 1 | inactive | - | - | inactive | |
 | KGPGFQWBCSZGEL-ZDUSSCGKSA-N | 1 | inactive | - | - | inactive | |
 | MYQAUKPBNJWPIE-UHFFFAOYSA-N | 1 | inactive | - | - | inactive | |
 | JWNPDZNEKVCWMY-UHFFFAOYSA-N | 1 | inactive | - | - | inactive | |
 | Imatinib | KTUFNOKKBVMGRW-UHFFFAOYSA-N | 1 | inactive | - | - | inactive |
 | Ruxolitinib | HFNKQEVNSGCOJV-OAHLLOKOSA-N | 1 | inactive | - | - | inactive |
| - | OLESUNNHPSUJLS-UHFFFAOYSA-N | 1 | active | - | - | active | |
 | SHPFDGWALWEPGS-UHFFFAOYSA-N | 1 | inactive | - | - | inactive | |
 | YYLKKYCXAOBSRM-UHFFFAOYSA-N | 1 | active | - | - | active | |
 | Lapatinib | BCFGMOOMADDAQU-UHFFFAOYSA-N | 1 | inactive | - | - | inactive |
 | UUADYKVKJIMIPA-UHFFFAOYSA-N | 1 | inactive | - | - | inactive | |
 | ZCBUQCWBWNUWSU-SFHVURJKSA-N | 1 | inactive | - | - | inactive | |
 | ZNOLRTPMNMPLHY-UHFFFAOYSA-N | 1 | inactive | - | - | inactive | |
 | UXXQOJXBIDBUAC-UHFFFAOYSA-N | 1 | inactive | - | - | inactive | |
 | HHFBDROWDBDFBR-UHFFFAOYSA-N | 1 | inactive | - | - | inactive | |
 | Nilotinib | HHZIURLSWUIHRB-UHFFFAOYSA-N | 1 | inactive | - | - | inactive |
 | Pazopanib | CUIHSIWYWATEQL-UHFFFAOYSA-N | 1 | active | - | - | active |
 | VAARYSWULJUGST-UHFFFAOYSA-N | 1 | inactive | - | - | inactive | |
 | OYONTEXKYJZFHA-OAQYLSRUSA-N | 1 | active | - | - | active | |
 | TUVCWJQQGGETHL-UHFFFAOYSA-N | 1 | inactive | - | - | inactive | |
 | BMGQWWVMWDBQGC-PZFYLCKJSA-N | 1 | inactive | - | - | inactive | |
 | YZDJQTHVDDOVHR-UHFFFAOYSA-N | 1 | inactive | - | - | inactive | |
| - | MTICIDWIKCANDD-UHFFFAOYSA-N | 1 | inactive | - | - | inactive | |
 | YCOYDOIWSSHVCK-UHFFFAOYSA-N | 1 | inactive | - | - | inactive | |
 | Tamatinib | NHHQJBCNYHBUSI-UHFFFAOYSA-N | 1 | inactive | - | - | inactive |
 | JRNJNYBQQYBCLE-UHFFFAOYSA-N | 1 | inactive | - | - | inactive | |
 | CDMGBJANTYXAIV-HHHXNRCGSA-N | 1 | inactive | - | - | inactive | |
 | BCZUAADEACICHN-UHFFFAOYSA-N | 1 | inactive | - | - | inactive | |
 | Bosutinib | UBPYILGKFZZVDX-UHFFFAOYSA-N | 1 | inactive | - | - | inactive |
 | Sorafenib | MLDQJTXFUGDVEO-UHFFFAOYSA-N | 1 | inactive | - | - | inactive |
 | HKSZLNNOFSGOKW-FYTWVXJKSA-N | 1 | inactive | - | - | inactive | |
 | CTNPALGJUAXMMC-PMFHANACSA-N | 1 | active | - | - | active | |
 | Sunitinib | WINHZLLDWRZWRT-ATVHPVEESA-N | 1 | active | - | - | active |
 | QQWUGDVOUVUTOY-UHFFFAOYSA-N | 1 | inactive | - | - | inactive | |
 | UJIAQDJKSXQLIT-UHFFFAOYSA-N | 1 | inactive | - | - | inactive | |
 | JOOXLOJCABQBSG-UHFFFAOYSA-N | 1 | inactive | - | - | inactive | |
 | Vandetanib | UHTHHESEBZOYNR-UHFFFAOYSA-N | 1 | inactive | - | - | inactive |
 | GCIKSSRWRFVXBI-UHFFFAOYSA-N | 1 | active | - | - | active | |
 | VEPKQEUBKLEPRA-UHFFFAOYSA-N | 1 | inactive | - | - | inactive | |
 | KNDPXYAMINMLED-UHFFFAOYSA-N | - | - | 3 | active | active | |
 | LSVIBAPJYUUVJJ-UHFFFAOYSA-N | - | - | 3 | exclude | exclude | |
 | OXFFBLXVJFWLLK-UHFFFAOYSA-N | - | - | 3 | active | active | |
 | GWTAOAWWDHYJKW-UHFFFAOYSA-N | - | - | 3 | active | active | |
 | CIUJFUBCFGKNHD-UHFFFAOYSA-N | - | - | 3 | exclude | exclude | |
 | IWNXEUPHZRHHNK-UHFFFAOYSA-N | - | - | 3 | exclude | exclude | |
 | WEPHZYIMARBFLD-UHFFFAOYSA-N | - | - | 3 | exclude | exclude | |
 | PPOHTLIVXPSOLN-UHFFFAOYSA-N | - | - | 3 | exclude | exclude | |
 | WEHLCQBCEXVDFL-UHFFFAOYSA-N | - | - | 3 | exclude | exclude | |
 | SLRYMOUSQMDJPH-UHFFFAOYSA-N | - | - | 5 | active | active | |
 | CUQNUTWHEMOZGU-UHFFFAOYSA-N | - | - | 3 | active | active | |
 | AMXYLFXYHCZHEV-UHFFFAOYSA-N | - | - | 3 | active | active | |
 | DCKXDFIWMOCNBS-UHFFFAOYSA-N | - | - | 3 | active | active | |
 | PUXQYEIQXOQBTI-UHFFFAOYSA-N | - | - | 3 | active | active | |
 | XHFYVNWXSOUNAK-UHFFFAOYSA-N | - | - | 3 | active | active | |
 | WEUBRKIFFZSMJY-UHFFFAOYSA-N | - | - | 3 | exclude | exclude | |
 | HQPGNAQSHLIGDV-UHFFFAOYSA-N | - | - | 3 | active | active | |
 | VNKUEEYDAKRQLH-UHFFFAOYSA-N | - | - | 3 | active | active | |
 | PVTFULWPKJRLFF-UHFFFAOYSA-N | - | - | 3 | active | active | |
 | QQTPMHCXBYRWFQ-UHFFFAOYSA-N | - | - | 3 | active | active | |
 | QFAPOWQTBPKCIL-UHFFFAOYSA-N | - | - | 3 | active | active | |
 | JSDJGQNZDVHBTJ-UHFFFAOYSA-N | - | - | 3 | active | active | |
 | STOIQAGAYIQTEP-UHFFFAOYSA-N | - | - | 3 | exclude | exclude | |
 | BASRWXZKOTYWGV-UHFFFAOYSA-N | - | - | 3 | exclude | exclude | |
 | FFELVARLIOWSSQ-UHFFFAOYSA-N | - | - | 3 | exclude | exclude | |
 | CNGLULHYIHCZMR-UHFFFAOYSA-N | - | - | 3 | exclude | exclude | |
 | WENIFNSHNVTKCT-UHFFFAOYSA-N | - | - | 3 | active | active | |
 | MIHYJIQBKUKKMZ-UHFFFAOYSA-N | - | - | 3 | exclude | exclude | |
 | SCAQPCRSYNOLDB-UHFFFAOYSA-N | - | - | 3 | active | active | |
 | VLTNUYNTYZRWQD-UHFFFAOYSA-N | - | - | 3 | exclude | exclude | |
 | UFWXSGVSQZKZTR-UHFFFAOYSA-N | - | - | 2 | exclude | exclude | |
 | HYHNNPKOTNCPJU-UHFFFAOYSA-N | - | - | 3 | exclude | exclude | |
 | IKUITEPQCFCQBL-UHFFFAOYSA-N | - | - | 3 | inactive | inactive | |
 | ZKOPOIXNUXDXMS-UHFFFAOYSA-N | - | - | 3 | inactive | inactive | |
 | BTAQQMMTAQWGCF-UHFFFAOYSA-N | - | - | 3 | inactive | inactive | |
 | WIKGAEMMNQTUGL-SNVBAGLBSA-N | - | - | 3 | exclude | exclude | |
 | KNOUWGGQMADIBV-KRWDZBQOSA-N | - | - | 4 | active | active | |
 | AWXYMMISTIIAIH-IBGZPJMESA-N | - | - | 3 | active | active | |
 | HMBAEAQKWTXBHE-KRWDZBQOSA-N | - | - | 6 | active | active | |
 | KSXXLKPPWYRQCT-HNNXBMFYSA-N | - | - | 2 | exclude | exclude | |
 | KXBWKWXLJDJUTG-KRWDZBQOSA-N | - | - | 3 | active | active | |
 | GCXSDJBPWVZLCU-KRWDZBQOSA-N | - | - | 1 | active | active | |
 | FILOHPAPJRJFDF-SFHVURJKSA-N | - | - | 3 | active | active | |
 | XLSNJTZNUHLDQC-SFHVURJKSA-N | - | - | 1 | active | active | |
 | ZMNTWFPENWVBQI-KRWDZBQOSA-N | - | - | 1 | active | active | |
 | SIDIZJFULUPVLJ-SFHVURJKSA-N | - | - | 1 | active | active | |
 | NIAHVVIUZUZDFS-KRWDZBQOSA-N | - | - | 1 | active | active | |
 | QIFUAERRNRWOHL-SFHVURJKSA-N | - | - | 3 | active | active | |
 | TXUWMXQFNYDOEZ-UHFFFAOYSA-N | - | - | 2 | exclude | exclude | |
 | AVYVHIKSFXVDBG-UHFFFAOYSA-N | - | - | 1 | active | active | |
 | WFVAIXPNICATFZ-NSHDSACASA-N | - | - | 1 | inactive | inactive | |
 | MGFSXSQOCMPBJP-HNNXBMFYSA-N | - | - | 2 | active | active | |
 | PCBOLQOPKUEBBQ-SFHVURJKSA-N | - | - | 2 | inactive | inactive | |
 | DSXDWWSCVQGTED-KRWDZBQOSA-N | - | - | 2 | exclude | exclude | |
 | LYPAFUINURXJSG-AWEZNQCLSA-N | - | - | 7 | active | active | |
 | ZAOHUZJRHLAEQB-INIZCTEOSA-N | - | - | 2 | inactive | inactive | |
 | BNFZELRXWKQQTE-AWEZNQCLSA-N | - | - | 2 | inactive | inactive | |
 | ULDZVSQOTVSBOS-INIZCTEOSA-N | - | - | 2 | inactive | inactive | |
 | DTHGKYMYOHZWJQ-KRWDZBQOSA-N | - | - | 2 | exclude | exclude | |
 | IEZROSAHMNRZNO-FQEVSTJZSA-N | - | - | 2 | active | active | |
 | LJJNVLRAHSNYBH-KRWDZBQOSA-N | - | - | 2 | exclude | exclude | |
 | BHGNGKHGBLRBON-INIZCTEOSA-N | - | - | 2 | inactive | inactive | |
 | YHGUHKWOKRNNEY-SFHVURJKSA-N | - | - | 2 | active | active | |
 | OJLFTGVMYJICFC-HNNXBMFYSA-N | - | - | 2 | active | active | |
 | MXFYWJGZIMCVJB-INIZCTEOSA-N | - | - | 2 | active | active | |
 | IIZWFTNGDCXXNB-IBGZPJMESA-N | - | - | 2 | active | active | |
 | NMALKWDSCYKLFE-KRWDZBQOSA-N | - | - | 2 | active | active | |
 | AEBVXDRUAUWPIF-SFHVURJKSA-N | - | - | 2 | active | active | |
 | BYZLFSSTPKOLGN-IBGZPJMESA-N | - | - | 2 | active | active | |
 | NLYLKUVVWLYFQA-INIZCTEOSA-N | - | - | 2 | active | active | |
 | PIWMULXWWGHQRV-SFHVURJKSA-N | - | - | 2 | active | active | |
 | UPZROLYOVJIAFN-AWEZNQCLSA-N | - | - | 2 | active | active | |
 | XSNVBMXTHDEJRZ-KRWDZBQOSA-N | - | - | 2 | active | active | |
 | SDSKXUMJPYXQBG-AWEZNQCLSA-N | - | - | 2 | active | active | |
 | NABLDJAKXWEMDU-SFHVURJKSA-N | - | - | 2 | active | active | |
 | JYJCMYZVWUPJEP-AWEZNQCLSA-N | - | - | 2 | active | active | |
 | QPQWAUBXMFKFMA-FQEVSTJZSA-N | - | - | 2 | active | active | |
 | JWKONLKXWPCOJF-IBGZPJMESA-N | - | - | 1 | active | active | |
 | WIKGAEMMNQTUGL-UHFFFAOYSA-N | - | - | 1 | inactive | inactive | |
 | JSKOFTDOVDUJQY-UHFFFAOYSA-N | - | - | 1 | inactive | inactive | |
 | JNZKENWWCGIHDV-UHFFFAOYSA-N | - | - | 1 | active | active | |
 | KDCYOEAWXNGQEB-UHFFFAOYSA-N | - | - | 1 | active | active | |
 | FXGOMJXGESCWPD-UHFFFAOYSA-N | - | - | 1 | active | active | |
 | HMBAEAQKWTXBHE-QGZVFWFLSA-N | - | - | 4 | inactive | inactive | |
 | SVDBBRBKNKIPIZ-AWEZNQCLSA-N | - | - | 2 | inactive | inactive | |
 | HRABCZBNSJGFHF-OAHLLOKOSA-N | - | - | 2 | inactive | inactive | |
 | KBCHZCAGZMGNKY-NRFANRHFSA-N | - | - | 2 | inactive | inactive | |
 | BSCAWJZUMKSTPZ-UHFFFAOYSA-N | - | - | 2 | inactive | inactive | |
 | NWRTYCXBUOHPGL-IBGZPJMESA-N | - | - | 2 | inactive | inactive | |
 | KSFRDMSRIFRFHD-BPQIPLTHSA-N | - | - | 1 | inactive | inactive | |
 | ZDSBJQYOCAGAGG-INIZCTEOSA-N | - | - | 2 | inactive | inactive | |
 | RRKCMOVROKRSEM-SFHVURJKSA-N | - | - | 2 | inactive | inactive |