Compound in Profiling

Compound Information

Test on : DRx, RBC, Metz, Millipore, GPCR

Compound Name
DRx, RBC, Metz, Millipore, GPCR : GW2580

Inchikey
Same : MYQAUKPBNJWPIE-N
DRx, RBC, Metz, Millipore, GPCR : MYQAUKPBNJWPIE-UHFFFAOYSA-N

ChemSpider
DRx, RBC, Metz, Millipore, GPCR : 9792308

Pubchem CID
DRx, RBC, Metz, Millipore, GPCR : 11617559

ChEMBL
DRx, RBC, Metz, Millipore, GPCR : CHEMBL261849

	DRx	RBC	Metz	Millipore	GPCR
bioactivity	Kd (nM)	Remain Activity (%)	Ki (nM)	Remain Activity (%)	Inhibition (%)
active criteria	<3000nM	<50%	<1000nM	<50%	>50%

Other

Test Member No. in Family
Family	no. Member on 518kinase	DRx	RBC	Metz	Millipore	GPCR
NAK	4	4	1	-	-	-
Aur	3	3	3	2	3	3
CAMKK	2	2	2	1	-	-
PEK	4	2	-	-	-	-
IRE	2	1	-	-	-	-
IKK	4	4	4	4	3	4
NEK	11	9	8	2	5	5
WEE	3	3	1	1	-	-
PLK	4	4	3	3	3	1
SgK496	1	1	1	-	-	-
NKF1	3	2	-	-	-	-
NKF4	2	1	-	-	-	-
ULK	5	4	3	-	2	-
TLK	2	2	1	-	1	-
TTK	1	1	1	-	-	1
Haspin	1	-	1	-	1	-
TOPK	1	-	1	1	-	-
WNK	4	-	2	-	2	-
CDC7	1	-	-	1	-	-

Other - NAK

Bioactivity
Kinase	DRx	RBC	Metz	Millipore	GPCR
AAK1	inactive (10001nM)	-	-	-	-
BIKE	inactive (10001nM)	-	-	-	-
GAK	inactive (10001nM)	-	-	-	-
MPSK1	inactive (10001nM)	inactive (106.22%)	-	-	-

Other - Aur

Bioactivity
Kinase	DRx	RBC	Metz	Millipore	GPCR
AurA	inactive (10001nM)	inactive (104.91%)	inactive (>1584.89nM)	inactive (108%)	inactive (2.3%)
AurB	inactive (10001nM)	inactive (103.66%)	inactive (>3981.07nM)	inactive (110%)	inactive (4.95%)
AurC	inactive (10001nM)	inactive (97.55%)	-	inactive (90%)	inactive (16.16%)

Other - CAMKK

Bioactivity
Kinase	DRx	RBC	Metz	Millipore	GPCR
CaMKK1	inactive (10001nM)	inactive (115.36%)	-	-	-
CaMKK2	inactive (10001nM)	inactive (102.6%)	-	-	-

Other - PEK

Bioactivity
Kinase	DRx	RBC	Metz	Millipore	GPCR
HRI	inactive (10001nM)	-	-	-	-
PKR	inactive (10001nM)	-	-	-	-

Other - IRE

Bioactivity
Kinase	DRx	RBC	Metz	Millipore	GPCR
IRE1	inactive (10001nM)	-	-	-	-

Other - IKK

Bioactivity
Kinase	DRx	RBC	Metz	Millipore	GPCR
IKKa	inactive (10001nM)	inactive (94.72%)	-	inactive (114%)	inactive (-7.71%)
IKKb	inactive (10001nM)	inactive (99.87%)	-	inactive (109%)	inactive (-1.34%)
IKKe	inactive (10001nM)	inactive (96.75%)	inactive (>3162.28nM)	-	inactive (-2.21%)
TBK1	inactive (10001nM)	inactive (102.72%)	inactive (>3162.28nM)	inactive (61%)	inactive (2.86%)

Other - NEK

Bioactivity
Kinase	DRx	RBC	Metz	Millipore	GPCR
NEK1	inactive (10001nM)	inactive (95.61%)	-	-	inactive (1.56%)
NEK11	inactive (10001nM)	inactive (102.92%)	-	inactive (110%)	-
NEK2	inactive (10001nM)	inactive (99.2%)	-	inactive (77%)	inactive (-1.4%)
NEK3	inactive (10001nM)	inactive (98.07%)	-	inactive (105%)	-
NEK4	inactive (10001nM)	inactive (92.24%)	-	-	-
NEK5	inactive (10001nM)	-	-	-	-
NEK6	inactive (10001nM)	inactive (99.42%)	-	inactive (97%)	inactive (-3.71%)
NEK7	inactive (10001nM)	inactive (100.37%)	-	inactive (96%)	inactive (1.75%)
NEK9	inactive (10001nM)	inactive (93.33%)	-	-	inactive (-4.1%)

Other - WEE

Bioactivity
Kinase	DRx	RBC	Metz	Millipore	GPCR
MYT1	inactive (10001nM)	-	-	-	-
Wee1	inactive (10001nM)	inactive (90.33%)	-	-	-
Wee1B	inactive (10001nM)	-	-	-	-

Other - PLK

Bioactivity
Kinase	DRx	RBC	Metz	Millipore	GPCR
PLK1	inactive (10001nM)	inactive (97.1%)	-	inactive (80%)	inactive (3.71%)
PLK2	inactive (10001nM)	inactive (115.91%)	-	inactive (98%)	-
PLK3	inactive (10001nM)	inactive (95.91%)	-	inactive (83%)	-
PLK4	inactive (10001nM)	-	-	-	-

Other - SgK496

Bioactivity
Kinase	DRx	RBC	Metz	Millipore	GPCR
SgK496	inactive (10001nM)	inactive (94.96%)	-	-	-

Other - NKF1

Bioactivity
Kinase	DRx	RBC	Metz	Millipore	GPCR
SBK	inactive (10001nM)	-	-	-	-
SgK110	inactive (10001nM)	-	-	-	-

Other - NKF4

Bioactivity
Kinase	DRx	RBC	Metz	Millipore	GPCR
CLIK1	inactive (10001nM)	-	-	-	-

Other - ULK

Bioactivity
Kinase	DRx	RBC	Metz	Millipore	GPCR
Fused	inactive (10001nM)	-	-	-	-
ULK1	inactive (10001nM)	inactive (99.68%)	-	-	-
ULK2	inactive (10001nM)	inactive (105.43%)	-	inactive (99%)	-
ULK3	inactive (10001nM)	active (0%)	-	inactive (99%)	-

Other - TLK

Bioactivity
Kinase	DRx	RBC	Metz	Millipore	GPCR
TLK1	inactive (10001nM)	-	-	-	-
TLK2	inactive (10001nM)	active (0%)	-	inactive (96%)	-

Other - TTK

Bioactivity
Kinase	DRx	RBC	Metz	Millipore	GPCR
TTK	inactive (10001nM)	inactive (105.27%)	-	-	inactive (3.14%)

Other - Haspin

Bioactivity
Kinase	DRx	RBC	Metz	Millipore	GPCR
Haspin	-	inactive (97.75%)	-	inactive (92%)	-

Other - TOPK

Bioactivity
Kinase	DRx	RBC	Metz	Millipore	GPCR
PBK	-	inactive (99.39%)	-	-	-

Other - WNK

Bioactivity
Kinase	DRx	RBC	Metz	Millipore	GPCR
Wnk2	-	inactive (94.6%)	-	inactive (106%)	-
Wnk3	-	inactive (100.44%)	-	inactive (108%)	-

Other - CDC7

Bioactivity
Kinase	DRx	RBC	Metz	Millipore	GPCR
CDC7	-	-	-	-	-

TK

Test Member No. in Family
Family	no. Member on 518kinase	DRx	RBC	Metz	Millipore	GPCR
Abl	2	2	2	1	2	2
ALK	2	2	2	2	1	2
Axl	3	3	3	2	3	3
Src	11	11	11	9	10	10
Tec	5	5	5	3	4	5
PDGFR	5	5	5	5	5	5
Csk	2	2	2	1	1	1
DDR	2	2	1	-	1	1
EGFR	4	4	3	3	2	3
Eph	14	13	12	1	11	6
FAK	2	2	2	2	2	1
Fer	2	2	2	2	2	2
FGFR	4	4	4	2	4	4
VEGFR	3	3	3	3	3	3
InsR	3	3	3	2	3	3
JakA	4	4	4	3	2	4
Met	2	2	2	2	2	2
Musk	1	1	1	-	1	1
Ret	1	1	1	1	1	1
Sev	1	1	1	1	1	1
Syk	2	2	2	1	2	2
Tie	2	2	1	-	1	1
Ack	2	2	1	1	1	2
Trk	3	3	3	3	2	3

TK - Abl

Bioactivity
Kinase	DRx	RBC	Metz	Millipore	GPCR
ABL1	inactive (10001nM)	inactive (101.84%)	inactive (>3981.07nM)	inactive (93%)	inactive (7.34%)
ABL2	inactive (10001nM)	inactive (106.95%)	-	inactive (113%)	inactive (5.98%)

TK - ALK

Bioactivity
Kinase	DRx	RBC	Metz	Millipore	GPCR
ALK	inactive (10001nM)	inactive (97.36%)	inactive (>6309.57nM)	inactive (74%)	inactive (0.01%)
LTK	inactive (10001nM)	inactive (100.44%)	inactive (>2511.89nM)	-	inactive (-0.41%)

TK - Axl

Bioactivity
Kinase	DRx	RBC	Metz	Millipore	GPCR
AXL	inactive (10001nM)	inactive (96.45%)	-	inactive (80%)	inactive (8.25%)
MER	inactive (10001nM)	inactive (90.25%)	-	inactive (108%)	inactive (3.48%)
TYRO3	inactive (10001nM)	inactive (109.93%)	inactive (>3162.28nM)	inactive (86%)	inactive (0.77%)

TK - Src

Bioactivity
Kinase	DRx	RBC	Metz	Millipore	GPCR
BLK	inactive (10001nM)	inactive (98.61%)	-	inactive (107%)	inactive (0.47%)
BRK	inactive (10001nM)	inactive (96.13%)	-	inactive (109%)	inactive (-1.6%)
FGR	inactive (10001nM)	inactive (92.3%)	-	inactive (101%)	inactive (4.25%)
FRK	inactive (10001nM)	inactive (101.56%)	-	inactive (102%)	inactive (2.07%)
FYN	inactive (10001nM)	inactive (102.15%)	inactive (>6309.57nM)	inactive (92%)	inactive (1.28%)
HCK	inactive (10001nM)	inactive (101.72%)	-	inactive (88%)	inactive (3.12%)
LCK	inactive (10001nM)	inactive (96.31%)	inactive (>6309.57nM)	inactive (110%)	inactive (2.78%)
LYN	inactive (10001nM)	inactive (99.94%)	-	inactive (104%)	-
SRC	inactive (10001nM)	inactive (97.85%)	-	inactive (84%)	inactive (1.97%)
SRM	inactive (10001nM)	inactive (95.94%)	-	-	inactive (1.88%)
YES	inactive (10001nM)	inactive (94.8%)	-	inactive (104%)	inactive (-3.3%)

TK - Tec

Bioactivity
Kinase	DRx	RBC	Metz	Millipore	GPCR
BMX	inactive (10001nM)	inactive (93.42%)	-	inactive (86%)	inactive (2.06%)
BTK	inactive (10001nM)	inactive (104.37%)	inactive (>6309.57nM)	inactive (103%)	inactive (3.61%)
ITK	inactive (10001nM)	inactive (98.14%)	-	inactive (100%)	inactive (2.31%)
TEC	inactive (10001nM)	inactive (113.91%)	-	-	inactive (2.91%)
TXK	inactive (10001nM)	inactive (101%)	-	inactive (83%)	inactive (4.97%)

TK - PDGFR

Bioactivity
Kinase	DRx	RBC	Metz	Millipore	GPCR
FMS	active (2.2nM)	active (19.3%)	active (39.81nM)	active (1%)	active (95.81%)
FLT3	inactive (10001nM)	inactive (102.71%)	inactive (>3162.28nM)	inactive (96%)	inactive (1.13%)
KIT	inactive (10001nM)	inactive (105.76%)	-	inactive (107%)	inactive (7.39%)
PDGFRa	inactive (10001nM)	inactive (99.43%)	inactive (>2511.89nM)	inactive (107%)	inactive (15.65%)
PDGFRb	inactive (10001nM)	inactive (98.2%)	inactive (>1995.26nM)	inactive (106%)	inactive (10.01%)

TK - Csk

Bioactivity
Kinase	DRx	RBC	Metz	Millipore	GPCR
CSK	inactive (10001nM)	inactive (101.18%)	-	inactive (105%)	inactive (-3.17%)
CTK	inactive (10001nM)	inactive (94.84%)	-	-	-

TK - DDR

Bioactivity
Kinase	DRx	RBC	Metz	Millipore	GPCR
DDR1	inactive (10001nM)	-	-	-	-
DDR2	inactive (10001nM)	inactive (99.57%)	-	inactive (112%)	inactive (8.13%)

TK - EGFR

Bioactivity
Kinase	DRx	RBC	Metz	Millipore	GPCR
EGFR	inactive (10001nM)	inactive (96.86%)	-	inactive (112%)	inactive (5.41%)
ErbB2	inactive (10001nM)	inactive (105.63%)	-	-	inactive (-2.79%)
ErbB3	inactive (10001nM)	-	-	-	-
ErbB4	inactive (10001nM)	inactive (109.79%)	-	inactive (99%)	inactive (3.43%)

TK - Eph

Bioactivity
Kinase	DRx	RBC	Metz	Millipore	GPCR
EphA1	inactive (10001nM)	inactive (85.75%)	-	inactive (96%)	-
EphA2	inactive (10001nM)	inactive (107.42%)	-	inactive (110%)	inactive (2.74%)
EphA3	inactive (10001nM)	inactive (109.36%)	-	inactive (108%)	inactive (0.08%)
EphA4	inactive (10001nM)	inactive (104.75%)	-	inactive (108%)	inactive (-0.14%)
EphA5	inactive (10001nM)	inactive (110.75%)	-	inactive (111%)	-
EphA6	inactive (10001nM)	-	-	-	-
EphA7	inactive (10001nM)	inactive (100.59%)	-	inactive (91%)	-
EphA8	inactive (10001nM)	inactive (98.05%)	-	inactive (93%)	-
EphB1	inactive (10001nM)	inactive (102.56%)	-	inactive (97%)	-
EphB2	inactive (10001nM)	inactive (87.4%)	-	inactive (108%)	inactive (8.3%)
EphB3	inactive (10001nM)	inactive (91.84%)	-	inactive (114%)	inactive (-4.82%)
EphB4	inactive (10001nM)	inactive (90.52%)	-	inactive (99%)	inactive (3.27%)
EphB6	inactive (10001nM)	-	-	-	-

TK - FAK

Bioactivity
Kinase	DRx	RBC	Metz	Millipore	GPCR
FAK	inactive (10001nM)	inactive (95.46%)	inactive (>6309.57nM)	inactive (115%)	-
PYK2	inactive (10001nM)	inactive (86.06%)	-	inactive (103%)	inactive (-2.43%)

TK - Fer

Bioactivity
Kinase	DRx	RBC	Metz	Millipore	GPCR
FER	inactive (10001nM)	inactive (93.36%)	-	inactive (107%)	inactive (2.33%)
FES	inactive (10001nM)	-	-	inactive (94%)	inactive (2.24%)

TK - FGFR

Bioactivity
Kinase	DRx	RBC	Metz	Millipore	GPCR
FGFR1	inactive (10001nM)	inactive (107.65%)	inactive (>3981.07nM)	inactive (112%)	inactive (2.1%)
FGFR2	inactive (10001nM)	inactive (101.66%)	-	inactive (112%)	inactive (6.83%)
FGFR3	inactive (10001nM)	inactive (105.01%)	-	inactive (108%)	inactive (0.98%)
FGFR4	inactive (10001nM)	inactive (99.66%)	-	inactive (131%)	inactive (3.16%)

TK - VEGFR

Bioactivity
Kinase	DRx	RBC	Metz	Millipore	GPCR
FLT1	inactive (10001nM)	inactive (99.66%)	inactive (>3981.07nM)	inactive (94%)	inactive (2.11%)
FLT4	inactive (10001nM)	inactive (105.08%)	-	inactive (95%)	inactive (-0.86%)
KDR	inactive (10001nM)	inactive (109.1%)	inactive (>2511.89nM)	inactive (97%)	inactive (9.65%)

TK - InsR

Bioactivity
Kinase	DRx	RBC	Metz	Millipore	GPCR
IGF1R	inactive (10001nM)	inactive (122.76%)	inactive (>2511.89nM)	inactive (128%)	inactive (-0.91%)
INSR	inactive (10001nM)	inactive (97.04%)	-	inactive (102%)	inactive (-1%)
IRR	inactive (10001nM)	inactive (99.37%)	-	inactive (137%)	inactive (-0.57%)

TK - JakA

Bioactivity
Kinase	DRx	RBC	Metz	Millipore	GPCR
JAK1	inactive (10001nM)	inactive (105.07%)	-	-	inactive (-0.05%)
JAK2	inactive (10001nM)	inactive (89.19%)	inactive (>2511.89nM)	inactive (101%)	inactive (4.19%)
JAK3	inactive (10001nM)	inactive (95.93%)	inactive (>5011.87nM)	inactive (105%)	inactive (3.61%)
TYK2	inactive (10001nM)	inactive (97.62%)	-	-	inactive (0.26%)

TK - Met

Bioactivity
Kinase	DRx	RBC	Metz	Millipore	GPCR
MET	inactive (10001nM)	inactive (76.12%)	inactive (>2511.89nM)	inactive (109%)	inactive (5.98%)
RON	inactive (10001nM)	inactive (103.86%)	inactive (>3981.07nM)	inactive (87%)	inactive (5.55%)

TK - Musk

Bioactivity
Kinase	DRx	RBC	Metz	Millipore	GPCR
MUSK	inactive (10001nM)	inactive (102.07%)	-	inactive (92%)	inactive (9.52%)

TK - Ret

Bioactivity
Kinase	DRx	RBC	Metz	Millipore	GPCR
RET	inactive (10001nM)	inactive (107.79%)	inactive (>3162.28nM)	inactive (92%)	inactive (9.77%)

TK - Sev

Bioactivity
Kinase	DRx	RBC	Metz	Millipore	GPCR
ROS	inactive (10001nM)	inactive (99.85%)	-	inactive (81%)	inactive (4.98%)

TK - Syk

Bioactivity
Kinase	DRx	RBC	Metz	Millipore	GPCR
SYK	inactive (10001nM)	inactive (88.99%)	-	inactive (118%)	inactive (0.65%)
ZAP70	inactive (10001nM)	inactive (94.33%)	-	inactive (93%)	inactive (4.05%)

TK - Tie

Bioactivity
Kinase	DRx	RBC	Metz	Millipore	GPCR
TIE1	inactive (10001nM)	-	-	-	-
TIE2	inactive (10001nM)	inactive (101.07%)	-	inactive (90%)	inactive (8.78%)

TK - Ack

Bioactivity
Kinase	DRx	RBC	Metz	Millipore	GPCR
TNK1	inactive (10001nM)	-	-	-	inactive (-8.3%)
ACK	inactive (10001nM)	inactive (105.22%)	inactive (>3981.07nM)	inactive (79%)	inactive (3.64%)

TK - Trk

Bioactivity
Kinase	DRx	RBC	Metz	Millipore	GPCR
TRKA	active (630nM)	inactive (51.33%)	inactive (1584.89nM)	active (49%)	inactive (49.99%)
TRKB	active (36nM)	active (31.23%)	active (158.49nM)	inactive (55%)	active (75.4%)
TRKC	active (120nM)	active (17.7%)	active (316.23nM)	-	active (72.72%)

TKL

Test Member No. in Family
Family	no. Member on 518kinase	DRx	RBC	Metz	Millipore	GPCR
STKR	12	10	5	1	2	-
RIPK	5	4	1	-	1	-
RAF	5	2	3	1	1	1
MLK	10	8	5	2	2	-
IRAK	4	3	2	2	2	1
LISK	4	3	1	1	1	-
LRRK	2	1	1	1	-	-

TKL - STKR

Bioactivity
Kinase	DRx	RBC	Metz	Millipore	GPCR
ALK2	inactive (10001nM)	inactive (100.04%)	inactive (>3981.07nM)	-	-
ALK4	inactive (10001nM)	inactive (97.82%)	-	inactive (120%)	-
ACTR2	inactive (10001nM)	-	-	-	-
ACTR2B	inactive (10001nM)	-	-	-	-
ALK1	inactive (10001nM)	inactive (100.56%)	-	-	-
BMPR1A	inactive (10001nM)	-	-	-	-
BMPR1B	inactive (10001nM)	-	-	-	-
BMPR2	inactive (10001nM)	-	-	-	-
TGFbR1	inactive (10001nM)	inactive (97.03%)	-	inactive (79%)	-
TGFbR2	inactive (10001nM)	inactive (126.76%)	-	-	-

TKL - RIPK

Bioactivity
Kinase	DRx	RBC	Metz	Millipore	GPCR
SgK288	inactive (10001nM)	-	-	-	-
RIPK1	inactive (10001nM)	-	-	-	-
RIPK2	inactive (10001nM)	inactive (81.95%)	-	inactive (83%)	-
ANKRD3	inactive (10001nM)	-	-	-	-

TKL - RAF

Bioactivity
Kinase	DRx	RBC	Metz	Millipore	GPCR
BRAF	inactive (10001nM)	inactive (98.96%)	-	-	inactive (-0.42%)
RAF1	inactive (10001nM)	inactive (97.03%)	-	inactive (86%)	-
ARAF	-	inactive (96.55%)	-	-	-

TKL - MLK

Bioactivity
Kinase	DRx	RBC	Metz	Millipore	GPCR
DLK	inactive (10001nM)	-	-	-	-
LZK	inactive (10001nM)	-	-	-	-
MLK1	inactive (10001nM)	inactive (104.62%)	-	inactive (91%)	-
MLK2	inactive (10001nM)	inactive (96.37%)	-	-	-
MLK3	inactive (10001nM)	inactive (100.55%)	-	-	-
TAK1	inactive (10001nM)	inactive (97.94%)	-	inactive (88%)	-
HH498	inactive (10001nM)	-	-	-	-
ZAK	inactive (10001nM)	inactive (97.41%)	-	-	-

TKL - IRAK

Bioactivity
Kinase	DRx	RBC	Metz	Millipore	GPCR
IRAK1	inactive (10001nM)	inactive (122.69%)	-	inactive (76%)	-
IRAK3	inactive (10001nM)	-	-	-	-
IRAK4	inactive (10001nM)	inactive (109.57%)	-	inactive (106%)	inactive (0.89%)

TKL - LISK

Bioactivity
Kinase	DRx	RBC	Metz	Millipore	GPCR
LIMK1	inactive (10001nM)	inactive (94.49%)	-	inactive (93%)	-
LIMK2	inactive (10001nM)	-	-	-	-
TESK1	inactive (10001nM)	-	-	-	-

TKL - LRRK

Bioactivity
Kinase	DRx	RBC	Metz	Millipore	GPCR
LRRK2	inactive (10001nM)	inactive (92.62%)	inactive (>2511.89nM)	-	-

Atypical

Test Member No. in Family
Family	no. Member on 518kinase	DRx	RBC	Metz	Millipore	GPCR
ABC1	5	2	-	-	-	-
PIKK	6	1	-	-	1	-
RIO	3	3	-	-	-	-
Alpha	6	1	-	1	1	-
PDHK	5	-	1	-	-	-

Atypical - ABC1

Bioactivity
Kinase	DRx	RBC	Metz	Millipore	GPCR
ADCK3	inactive (10001nM)	-	-	-	-
ADCK4	inactive (10001nM)	-	-	-	-

Atypical - PIKK

Bioactivity
Kinase	DRx	RBC	Metz	Millipore	GPCR
FRAP	inactive (10001nM)	-	-	inactive (116%)	-

Atypical - RIO

Bioactivity
Kinase	DRx	RBC	Metz	Millipore	GPCR
RIOK1	inactive (10001nM)	-	-	-	-
RIOK2	inactive (10001nM)	-	-	-	-
RIOK3	inactive (10001nM)	-	-	-	-

Atypical - Alpha

Bioactivity
Kinase	DRx	RBC	Metz	Millipore	GPCR
ChaK2	inactive (10001nM)	-	-	-	-
eEF2K	-	-	-	inactive (92%)	-

Atypical - PDHK

Bioactivity
Kinase	DRx	RBC	Metz	Millipore	GPCR
PDHK1	-	inactive (89.44%)	-	-	-

AGC

Test Member No. in Family
Family	no. Member on 518kinase	DRx	RBC	Metz	Millipore	GPCR
Akt	3	3	3	3	3	3
DMPK	7	7	5	3	5	4
GRK	7	3	6	1	3	2
NDR	4	4	1	-	-	-
MAST	5	1	-	-	-	-
PDK1	1	1	1	1	1	1
PKA	5	3	3	2	2	1
PKN	3	2	2	1	1	-
PKC	9	5	9	5	8	5
PKG	2	2	3	2	-	2
RSK	8	1	8	4	7	7
SGK	3	1	3	1	3	3
YANK	3	3	-	-	-	-

AGC - Akt

Bioactivity
Kinase	DRx	RBC	Metz	Millipore	GPCR
AKT1	inactive (10001nM)	inactive (97.39%)	-	inactive (106%)	inactive (-0.15%)
AKT2	inactive (10001nM)	inactive (102.47%)	-	inactive (88%)	inactive (-0.17%)
AKT3	inactive (10001nM)	inactive (96.52%)	-	inactive (98%)	inactive (0.93%)

AGC - DMPK

Bioactivity
Kinase	DRx	RBC	Metz	Millipore	GPCR
CRIK	inactive (10001nM)	-	-	-	-
DMPK1	inactive (10001nM)	inactive (101.27%)	-	inactive (115%)	-
DMPK2	inactive (10001nM)	-	-	-	-
MRCKa	inactive (10001nM)	inactive (94.45%)	-	inactive (102%)	inactive (-0.63%)
MRCKb	inactive (10001nM)	inactive (96.93%)	-	inactive (91%)	inactive (3.93%)
ROCK1	inactive (10001nM)	inactive (100.07%)	inactive (>3981.07nM)	inactive (112%)	inactive (2.94%)
ROCK2	inactive (10001nM)	inactive (84.13%)	-	inactive (88%)	inactive (-1.22%)

AGC - GRK

Bioactivity
Kinase	DRx	RBC	Metz	Millipore	GPCR
RHOK	inactive (10001nM)	-	-	-	-
GPRK4	inactive (10001nM)	inactive (106%)	-	-	-
GPRK7	inactive (10001nM)	inactive (103.77%)	-	inactive (88%)	inactive (-7.03%)
BARK1	-	inactive (96.08%)	-	-	-
BARK2	-	inactive (103.15%)	-	-	-
GPRK5	-	inactive (108.55%)	inactive (>3981.07nM)	inactive (83%)	-
GPRK6	-	inactive (99.76%)	-	inactive (95%)	inactive (-5.27%)

AGC - NDR

Bioactivity
Kinase	DRx	RBC	Metz	Millipore	GPCR
LATS1	inactive (10001nM)	-	-	-	-
LATS2	inactive (10001nM)	-	-	-	-
NDR1	inactive (10001nM)	active (0%)	-	-	-
NDR2	inactive (10001nM)	-	-	-	-

AGC - MAST

Bioactivity
Kinase	DRx	RBC	Metz	Millipore	GPCR
MAST1	inactive (10001nM)	-	-	-	-

AGC - PDK1

Bioactivity
Kinase	DRx	RBC	Metz	Millipore	GPCR
PDK1	inactive (10001nM)	inactive (89.44%)	-	inactive (104%)	inactive (2.38%)

AGC - PKA

Bioactivity
Kinase	DRx	RBC	Metz	Millipore	GPCR
PKACa	inactive (10001nM)	inactive (104.38%)	inactive (>1258.93nM)	inactive (108%)	-
PKACb	inactive (10001nM)	-	-	-	-
PRKX	inactive (10001nM)	inactive (104.5%)	inactive (>3162.28nM)	inactive (98%)	inactive (1.07%)
PKACg	-	-	-	-	-

AGC - PKN

Bioactivity
Kinase	DRx	RBC	Metz	Millipore	GPCR
PKN1	inactive (10001nM)	inactive (101.02%)	-	-	-
PKN2	inactive (10001nM)	inactive (90.9%)	-	inactive (99%)	-

AGC - PKC

Bioactivity
Kinase	DRx	RBC	Metz	Millipore	GPCR
PKCd	inactive (10001nM)	inactive (87.82%)	-	inactive (98%)	-
PKCe	inactive (10001nM)	inactive (95.66%)	-	inactive (89%)	-
PKCh	inactive (10001nM)	inactive (88.56%)	-	inactive (96%)	inactive (-0.03%)
PKCi	inactive (10001nM)	inactive (91.58%)	-	inactive (97%)	inactive (2.56%)
PKCt	inactive (10001nM)	inactive (97.97%)	inactive (>2511.89nM)	inactive (88%)	inactive (-0.58%)
PKCa	-	inactive (95.9%)	-	inactive (103%)	inactive (1.13%)
PKCg	-	inactive (101.71%)	-	inactive (103%)	inactive (0.23%)
PKCz	-	inactive (93.37%)	-	inactive (101%)	-
PKCb	-	inactive (109.6%)	-	-	-

AGC - PKG

Bioactivity
Kinase	DRx	RBC	Metz	Millipore	GPCR
PKG1	inactive (10001nM)	inactive (98.33%)	-	-	inactive (3.2%)
PKG2	inactive (10001nM)	inactive (103.91%)	-	-	inactive (3.2%)

AGC - RSK

Bioactivity
Kinase	DRx	RBC	Metz	Millipore	GPCR
p70S6K	inactive (10001nM)	inactive (89.46%)	-	inactive (80%)	inactive (0.73%)
MSK1	-	inactive (103.15%)	-	inactive (131%)	inactive (5.97%)
MSK2	-	inactive (107.09%)	-	inactive (91%)	inactive (1.84%)
p70S6Kb	-	inactive (100.3%)	-	-	-
RSK2	-	inactive (104.9%)	inactive (>3981.07nM)	inactive (64%)	inactive (-0.8%)
RSK4	-	inactive (100.52%)	-	inactive (110%)	inactive (-0.61%)
RSK1	-	inactive (92.69%)	-	inactive (94%)	inactive (-1.81%)
RSK3	-	inactive (104.93%)	-	inactive (131%)	inactive (-1%)

AGC - SGK

Bioactivity
Kinase	DRx	RBC	Metz	Millipore	GPCR
SGK3	inactive (10001nM)	inactive (105.06%)	-	inactive (87%)	inactive (1.28%)
SGK1	-	inactive (97.88%)	-	inactive (105%)	inactive (1.31%)
SGK2	-	inactive (97.54%)	-	inactive (108%)	inactive (3%)

AGC - YANK

Bioactivity
Kinase	DRx	RBC	Metz	Millipore	GPCR
YANK1	inactive (10001nM)	-	-	-	-
YANK2	inactive (10001nM)	-	-	-	-
YANK3	inactive (10001nM)	-	-	-	-

CAMK

Test Member No. in Family
Family	no. Member on 518kinase	DRx	RBC	Metz	Millipore	GPCR
CAMKL	20	19	13	9	12	13
CAMK1	5	4	5	2	3	2
CAMK2	4	4	4	4	3	2
CASK	1	1	-	-	-	-
RAD53	1	1	1	1	1	1
DAPK	5	5	4	2	4	1
DCAMKL	3	3	1	1	1	1
MAPKAPK	5	4	5	4	4	5
MLCK	5	4	2	-	1	-
PHK	2	2	2	1	1	2
PIM	3	3	3	3	3	3
PKD	3	3	3	2	2	3
STK33	1	1	-	1	-	-
TSSK	5	1	2	2	2	2

CAMK - CAMKL

Bioactivity
Kinase	DRx	RBC	Metz	Millipore	GPCR
AMPKa1	inactive (10001nM)	-	inactive (>3162.28nM)	inactive (90%)	inactive (-0.28%)
AMPKa2	inactive (10001nM)	-	-	inactive (94%)	inactive (2.37%)
NuaK1	inactive (10001nM)	inactive (106.25%)	-	inactive (91%)	inactive (3.71%)
BRSK1	inactive (10001nM)	inactive (95.59%)	-	inactive (89%)	inactive (3.19%)
BRSK2	inactive (10001nM)	inactive (96.78%)	-	inactive (99%)	inactive (2.49%)
CHK1	inactive (10001nM)	inactive (106.75%)	-	inactive (91%)	inactive (7.23%)
HUNK	inactive (10001nM)	-	-	-	-
LKB1	inactive (10001nM)	inactive (103.19%)	-	inactive (106%)	-
MARK1	inactive (10001nM)	inactive (103.3%)	-	inactive (80%)	inactive (0.09%)
MARK2	inactive (10001nM)	inactive (105.58%)	-	inactive (106%)	-
MARK3	inactive (10001nM)	inactive (103.12%)	-	-	inactive (2.06%)
MARK4	inactive (10001nM)	inactive (89.74%)	-	-	inactive (1.47%)
MELK	inactive (10001nM)	inactive (101.85%)	-	inactive (89%)	inactive (-1.43%)
NIM1	inactive (10001nM)	-	-	-	-
QSK	inactive (10001nM)	-	-	-	-
SIK	inactive (10001nM)	-	-	inactive (86%)	inactive (2.92%)
QIK	inactive (10001nM)	inactive (98.58%)	-	-	inactive (-1.07%)
NuaK2	inactive (10001nM)	inactive (98.12%)	-	-	-
SNRK	inactive (10001nM)	-	-	-	-
PASK	-	inactive (102.98%)	-	inactive (79%)	inactive (0.54%)

CAMK - CAMK1

Bioactivity
Kinase	DRx	RBC	Metz	Millipore	GPCR
CaMK1a	inactive (10001nM)	inactive (102.78%)	-	inactive (105%)	-
CaMK1d	inactive (10001nM)	inactive (93.02%)	inactive (>2511.89nM)	inactive (103%)	inactive (5.51%)
CaMK1g	inactive (10001nM)	inactive (98.28%)	-	-	-
CaMK4	inactive (10001nM)	inactive (94.66%)	-	inactive (130%)	inactive (3.54%)
CaMK1b	-	inactive (98.44%)	-	-	-

CAMK - CAMK2

Bioactivity
Kinase	DRx	RBC	Metz	Millipore	GPCR
CaMK2a	inactive (10001nM)	inactive (104.73%)	inactive (>7943.28nM)	-	inactive (5.8%)
CaMK2b	inactive (10001nM)	inactive (100.21%)	-	inactive (91%)	-
CaMK2d	inactive (10001nM)	inactive (109.11%)	-	inactive (101%)	inactive (2.5%)
CaMK2g	inactive (10001nM)	inactive (94.36%)	-	inactive (97%)	-

CAMK - CASK

Bioactivity
Kinase	DRx	RBC	Metz	Millipore	GPCR
CASK	inactive (10001nM)	-	-	-	-

CAMK - RAD53

Bioactivity
Kinase	DRx	RBC	Metz	Millipore	GPCR
CHK2	inactive (10001nM)	inactive (106.71%)	-	inactive (97%)	inactive (4.77%)

CAMK - DAPK

Bioactivity
Kinase	DRx	RBC	Metz	Millipore	GPCR
DAPK1	inactive (10001nM)	inactive (101.52%)	-	inactive (94%)	inactive (9.42%)
DAPK2	inactive (10001nM)	inactive (95.26%)	-	inactive (106%)	-
DAPK3	inactive (10001nM)	inactive (104.3%)	inactive (>5011.87nM)	inactive (96%)	-
DRAK1	inactive (10001nM)	inactive (102.41%)	-	inactive (112%)	-
DRAK2	inactive (10001nM)	-	-	-	-

CAMK - DCAMKL

Bioactivity
Kinase	DRx	RBC	Metz	Millipore	GPCR
DCLK1	inactive (10001nM)	-	-	-	-
DCLK2	inactive (10001nM)	inactive (101.19%)	-	inactive (105%)	inactive (8.82%)
DCLK3	inactive (10001nM)	-	-	-	-

CAMK - MAPKAPK

Bioactivity
Kinase	DRx	RBC	Metz	Millipore	GPCR
MAPKAPK2	inactive (10001nM)	inactive (102.73%)	-	inactive (84%)	inactive (3.22%)
MAPKAPK5	inactive (10001nM)	inactive (87.52%)	-	inactive (81%)	inactive (-1.74%)
MNK1	inactive (10001nM)	inactive (113.09%)	-	-	inactive (0.82%)
MNK2	inactive (10001nM)	inactive (90.59%)	-	inactive (108%)	inactive (0.25%)
MAPKAPK3	-	inactive (95.97%)	-	inactive (125%)	inactive (7.43%)

CAMK - MLCK

Bioactivity
Kinase	DRx	RBC	Metz	Millipore	GPCR
caMLCK	inactive (10001nM)	-	-	-	-
smMLCK	inactive (10001nM)	inactive (95.68%)	-	inactive (83%)	-
skMLCK	inactive (10001nM)	inactive (104.21%)	-	-	-
SgK085	inactive (10001nM)	-	-	-	-

CAMK - PHK

Bioactivity
Kinase	DRx	RBC	Metz	Millipore	GPCR
PHKg1	inactive (10001nM)	inactive (95.29%)	-	-	inactive (1.56%)
PHKg2	inactive (10001nM)	inactive (105.6%)	-	inactive (91%)	inactive (-1.66%)

CAMK - PIM

Bioactivity
Kinase	DRx	RBC	Metz	Millipore	GPCR
PIM1	inactive (10001nM)	inactive (103.56%)	inactive (>6309.57nM)	inactive (97%)	inactive (0.49%)
PIM2	inactive (10001nM)	inactive (107.01%)	-	inactive (96%)	inactive (3.29%)
PIM3	inactive (10001nM)	inactive (95.86%)	-	inactive (90%)	inactive (0.23%)

CAMK - PKD

Bioactivity
Kinase	DRx	RBC	Metz	Millipore	GPCR
PKD1	inactive (10001nM)	inactive (95.21%)	-	inactive (81%)	inactive (2.03%)
PKD2	inactive (10001nM)	inactive (99.4%)	-	inactive (101%)	inactive (4.2%)
PKD3	inactive (10001nM)	inactive (97.11%)	inactive (>3981.07nM)	-	inactive (2.56%)

CAMK - STK33

Bioactivity
Kinase	DRx	RBC	Metz	Millipore	GPCR
STK33	inactive (10001nM)	inactive (96.37%)	-	inactive (108%)	-

CAMK - TSSK

Bioactivity
Kinase	DRx	RBC	Metz	Millipore	GPCR
TSSK1	inactive (10001nM)	inactive (95.22%)	-	inactive (91%)	inactive (-1.27%)
TSSK2	-	inactive (109.38%)	-	inactive (93%)	inactive (-0.65%)

STE

Test Member No. in Family
Family	no. Member on 518kinase	DRx	RBC	Metz	Millipore	GPCR
STE11	8	8	3	-	1	-
STE20	31	27	23	9	14	12
STE7	7	7	3	2	3	1
STE-Unique	2	-	2	-	-	-

STE - STE11

Bioactivity
Kinase	DRx	RBC	Metz	Millipore	GPCR
MAP3K5	inactive (10001nM)	inactive (89%)	-	inactive (85%)	-
MAP3K6	inactive (10001nM)	-	-	-	-
MAP3K1	inactive (10001nM)	-	-	-	-
MAP3K7	inactive (10001nM)	-	-	-	-
MAP3K2	inactive (10001nM)	inactive (108.43%)	-	-	-
MAP3K3	inactive (10001nM)	inactive (97.78%)	-	-	-
MAP3K4	inactive (10001nM)	-	-	-	-
MAP3K8	inactive (10001nM)	-	-	-	-

STE - STE20

Bioactivity
Kinase	DRx	RBC	Metz	Millipore	GPCR
HPK1	inactive (10001nM)	-	-	-	-
LOK	inactive (10001nM)	inactive (100.03%)	-	inactive (88%)	inactive (7.31%)
GCK	inactive (10001nM)	inactive (119.84%)	inactive (>2511.89nM)	inactive (83%)	inactive (3.99%)
KHS2	inactive (10001nM)	-	-	-	-
HGK	inactive (10001nM)	inactive (98.97%)	inactive (>5011.87nM)	-	inactive (6.03%)
KHS1	inactive (10001nM)	inactive (97.43%)	-	-	-
MINK	inactive (10001nM)	inactive (86.53%)	-	inactive (84%)	inactive (4.81%)
MST1	inactive (10001nM)	inactive (106.11%)	-	inactive (93%)	inactive (4.23%)
MST2	inactive (10001nM)	inactive (98.38%)	-	inactive (105%)	inactive (3.04%)
MST3	inactive (10001nM)	inactive (93.55%)	-	inactive (61%)	-
MST4	inactive (10001nM)	inactive (95.52%)	-	-	inactive (0.63%)
MYO3A	inactive (10001nM)	-	-	-	-
MYO3B	inactive (10001nM)	active (0%)	-	-	-
OSR1	inactive (10001nM)	inactive (103.2%)	-	-	-
PAK1	inactive (10001nM)	inactive (93.36%)	-	-	inactive (5.79%)
PAK2	inactive (10001nM)	inactive (95.27%)	-	inactive (98%)	inactive (0.32%)
PAK3	inactive (10001nM)	inactive (101.66%)	-	inactive (73%)	inactive (1.06%)
PAK4	inactive (10001nM)	inactive (101.39%)	inactive (>5011.87nM)	inactive (99%)	-
PAK6	inactive (10001nM)	inactive (94.86%)	-	inactive (112%)	inactive (-2.29%)
PAK5	inactive (10001nM)	inactive (102.83%)	-	inactive (86%)	inactive (7.84%)
SLK	inactive (10001nM)	inactive (97.74%)	-	-	-
STLK3	inactive (10001nM)	inactive (87.58%)	-	-	-
TAO1	inactive (10001nM)	inactive (109.59%)	inactive (>6309.57nM)	inactive (95%)	-
TAO2	inactive (10001nM)	inactive (94.74%)	-	inactive (100%)	-
TAO3	inactive (10001nM)	inactive (102.2%)	-	inactive (95%)	-
TNIK	inactive (10001nM)	-	-	-	-
YSK1	inactive (10001nM)	inactive (96.95%)	-	-	-

STE - STE7

Bioactivity
Kinase	DRx	RBC	Metz	Millipore	GPCR
MAP2K1	inactive (10001nM)	inactive (98.64%)	inactive (>3162.28nM)	inactive (100%)	inactive (0.97%)
MAP2K2	inactive (10001nM)	inactive (101.23%)	inactive (>3981.07nM)	-	-
MAP2K3	inactive (10001nM)	-	-	-	-
MAP2K4	inactive (10001nM)	-	-	-	-
MAP2K5	inactive (10001nM)	-	-	-	-
MAP2K6	inactive (10001nM)	inactive (87.4%)	-	inactive (78%)	-
MAP2K7	inactive (10001nM)	-	-	inactive (113%)	-

STE - STE-Unique

Bioactivity
Kinase	DRx	RBC	Metz	Millipore	GPCR
COT	-	inactive (98.35%)	-	-	-
NIK	-	inactive (81.77%)	-	-	-

CMGC

Test Member No. in Family
Family	no. Member on 518kinase	DRx	RBC	Metz	Millipore	GPCR
CDK	20	8	-	7	-	-
CDKL	5	4	-	-	-	-
CLK	4	4	4	2	2	2
CK2	3	2	2	1	2	1
DYRK	10	8	9	6	4	5
MAPK	14	14	10	8	10	6
GSK	2	2	2	2	2	2
RCK	3	2	-	-	-	-
SRPK	3	3	3	1	3	2

CMGC - CDK

Bioactivity
Kinase	DRx	RBC	Metz	Millipore	GPCR
PITSLRE	inactive (10001nM)	-	-	-	-
CHED	inactive (10001nM)	-	-	-	-
CDK11	inactive (10001nM)	-	-	-	-
PCTAIRE1	inactive (10001nM)	-	-	-	-
PCTAIRE2	inactive (10001nM)	-	-	-	-
PCTAIRE3	inactive (10001nM)	-	-	-	-
PFTAIRE2	inactive (10001nM)	-	-	-	-
PFTAIRE1	inactive (10001nM)	-	-	-	-
CDC2	-	-	-	-	-
CDK2	-	-	-	-	-
CDK5	-	-	inactive (>3162.28nM)	-	-
CDK8	-	-	inactive (>3981.07nM)	-	-
CDK7	-	-	inactive (>3981.07nM)	-	-
CDK9	-	-	inactive (>1584.89nM)	-	-

CMGC - CDKL

Bioactivity
Kinase	DRx	RBC	Metz	Millipore	GPCR
CDKL1	inactive (10001nM)	-	-	-	-
CDKL2	inactive (10001nM)	-	-	-	-
CDKL3	inactive (10001nM)	-	-	-	-
CDKL5	inactive (10001nM)	-	-	-	-

CMGC - CLK

Bioactivity
Kinase	DRx	RBC	Metz	Millipore	GPCR
CLK1	inactive (10001nM)	inactive (102.63%)	-	-	-
CLK2	inactive (10001nM)	inactive (94.33%)	inactive (>3981.07nM)	inactive (108%)	inactive (1.66%)
CLK3	inactive (10001nM)	inactive (98.34%)	-	inactive (86%)	inactive (-0.53%)
CLK4	inactive (10001nM)	inactive (86.5%)	inactive (>2511.89nM)	-	-

CMGC - CK2

Bioactivity
Kinase	DRx	RBC	Metz	Millipore	GPCR
CK2a1	inactive (10001nM)	inactive (104.85%)	-	inactive (86%)	inactive (-8.59%)
CK2a2	inactive (10001nM)	inactive (97.35%)	-	inactive (110%)	-

CMGC - DYRK

Bioactivity
Kinase	DRx	RBC	Metz	Millipore	GPCR
DYRK1A	inactive (10001nM)	inactive (88.12%)	inactive (>1995.26nM)	-	inactive (0.52%)
DYRK1B	inactive (10001nM)	inactive (104.29%)	inactive (>2511.89nM)	-	inactive (2.57%)
DYRK2	inactive (10001nM)	inactive (104.62%)	-	inactive (97%)	inactive (0.42%)
HIPK1	inactive (10001nM)	inactive (109.76%)	-	inactive (107%)	inactive (0.13%)
HIPK2	inactive (10001nM)	inactive (102.6%)	-	inactive (100%)	-
HIPK3	inactive (10001nM)	inactive (102.19%)	-	inactive (92%)	-
HIPK4	inactive (10001nM)	inactive (97.69%)	-	-	inactive (4.49%)
PRP4	inactive (10001nM)	-	-	-	-
DYRK3	-	inactive (108.33%)	-	-	-
DYRK4	-	inactive (101.36%)	-	-	-

CMGC - MAPK

Bioactivity
Kinase	DRx	RBC	Metz	Millipore	GPCR
Erk1	inactive (10001nM)	inactive (99.11%)	-	inactive (100%)	inactive (0.29%)
Erk2	inactive (10001nM)	inactive (109.54%)	-	inactive (102%)	inactive (-0.13%)
Erk3	inactive (10001nM)	-	-	-	-
Erk4	inactive (10001nM)	-	-	-	-
Erk5	inactive (10001nM)	-	-	-	-
Erk7	inactive (10001nM)	-	-	-	-
JNK1	inactive (10001nM)	inactive (91.91%)	inactive (>5011.87nM)	inactive (101%)	-
JNK2	inactive (10001nM)	inactive (106.24%)	inactive (>3981.07nM)	inactive (105%)	inactive (0.51%)
JNK3	inactive (10001nM)	inactive (84.42%)	-	inactive (89%)	-
NLK	inactive (10001nM)	inactive (105.31%)	-	inactive (97%)	-
p38a	inactive (10001nM)	inactive (106.22%)	inactive (>3981.07nM)	inactive (84%)	inactive (4.45%)
p38b	inactive (10001nM)	inactive (98.68%)	-	inactive (95%)	inactive (1%)
p38d	inactive (10001nM)	inactive (96.04%)	-	inactive (111%)	inactive (0.37%)
p38g	inactive (10001nM)	inactive (101.82%)	-	inactive (88%)	-

CMGC - GSK

Bioactivity
Kinase	DRx	RBC	Metz	Millipore	GPCR
GSK3A	inactive (10001nM)	inactive (108.17%)	inactive (>3981.07nM)	inactive (120%)	inactive (0.34%)
GSK3B	inactive (10001nM)	inactive (97.76%)	inactive (>3981.07nM)	inactive (106%)	inactive (0.94%)

CMGC - RCK

Bioactivity
Kinase	DRx	RBC	Metz	Millipore	GPCR
ICK	inactive (10001nM)	-	-	-	-
MAK	inactive (10001nM)	-	-	-	-

CMGC - SRPK

Bioactivity
Kinase	DRx	RBC	Metz	Millipore	GPCR
SRPK1	inactive (10001nM)	inactive (90.37%)	-	inactive (99%)	inactive (-2.52%)
SRPK2	inactive (10001nM)	inactive (87.44%)	-	inactive (91%)	-
MSSK1	inactive (10001nM)	inactive (102.33%)	-	inactive (111%)	inactive (0.79%)

CK1

Test Member No. in Family
Family	no. Member on 518kinase	DRx	RBC	Metz	Millipore	GPCR
CK1	7	7	6	5	4	4
VRK	3	1	1	-	1	-

CK1 - CK1

Bioactivity
Kinase	DRx	RBC	Metz	Millipore	GPCR
CK1a	inactive (10001nM)	inactive (97.93%)	inactive (>3981.07nM)	-	inactive (0.48%)
CK1a2	inactive (10001nM)	-	-	-	-
CK1d	inactive (10001nM)	inactive (98.52%)	-	inactive (88%)	-
CK1e	inactive (10001nM)	inactive (97.08%)	-	-	-
CK1g1	inactive (10001nM)	inactive (92.7%)	-	inactive (103%)	inactive (-0.45%)
CK1g2	inactive (10001nM)	inactive (100.57%)	-	inactive (89%)	inactive (0.05%)
CK1g3	inactive (10001nM)	inactive (102.62%)	-	inactive (103%)	inactive (0.85%)

CK1 - VRK

Bioactivity
Kinase	DRx	RBC	Metz	Millipore	GPCR
VRK2	inactive (10001nM)	-	-	inactive (92%)	-
VRK1	-	inactive (91.39%)	-	-	-