Compound in Profiling

Compound Information

Test on : RBC, Metz, Millipore

Compound Name
RBC, Metz : 134036-52-5
Millipore : 133550-30-8

Inchikey
Same : TUCIOBMMDDOEMM-N
RBC, Metz : TUCIOBMMDDOEMM-UHFFFAOYSA-N
Millipore : TUCIOBMMDDOEMM-RIYZIHGNSA-N

ChemSpider
RBC, Metz : 2298
Millipore : 4485941

Pubchem CID
RBC, Metz : 2390
Millipore : 5328779

ChEMBL
RBC, Metz : CHEMBL1974157
Millipore : CHEMBL56543

RBC, Metz	Millipore

	DRx	RBC	Metz	Millipore	GPCR
bioactivity	Kd (nM)	Remain Activity (%)	Ki (nM)	Remain Activity (%)	Inhibition (%)
active criteria	<3000nM	<50%	<1000nM	<50%	>50%

AGC

Test Member No. in Family
Family	no. Member on 518kinase	RBC	Metz	Millipore
PDK1	1	1	1	1
Akt	3	3	3	3
DMPK	7	5	3	5
GRK	7	6	1	3
RSK	8	8	4	7
PKA	5	3	2	2
PKC	9	9	5	8
PKG	2	3	2	-
PKN	3	2	1	1
SGK	3	3	1	3
NDR	4	1	-	-

AGC - PDK1

Bioactivity
Kinase	RBC	Metz	Millipore
PDK1	inactive (73.99%)	-	inactive (109%)

AGC - Akt

Bioactivity
Kinase	RBC	Metz	Millipore
AKT1	inactive (101.29%)	inactive (>7943.28nM)	inactive (103%)
AKT2	inactive (98.44%)	inactive (>7943.28nM)	inactive (120%)
AKT3	inactive (90.77%)	inactive (>10000nM)	inactive (96%)

AGC - DMPK

Bioactivity
Kinase	RBC	Metz	Millipore
DMPK1	inactive (99.67%)	-	inactive (106%)
MRCKa	inactive (99.37%)	inactive (>10000nM)	inactive (95%)
MRCKb	inactive (103.08%)	-	inactive (87%)
ROCK1	inactive (99.67%)	inactive (>10000nM)	inactive (106%)
ROCK2	inactive (93.97%)	inactive (>7943.28nM)	inactive (103%)

AGC - GRK

Bioactivity
Kinase	RBC	Metz	Millipore
BARK1	inactive (96.58%)	-	-
BARK2	inactive (91.42%)	-	-
GPRK4	inactive (100.78%)	-	-
GPRK5	inactive (107.65%)	-	inactive (100%)
GPRK6	inactive (100.56%)	-	inactive (99%)
GPRK7	inactive (103.16%)	-	inactive (99%)

AGC - RSK

Bioactivity
Kinase	RBC	Metz	Millipore
MSK1	inactive (102.2%)	-	inactive (109%)
MSK2	inactive (94.17%)	-	inactive (86%)
p70S6K	inactive (92.77%)	inactive (>6309.57nM)	inactive (108%)
p70S6Kb	inactive (94.72%)	-	-
RSK2	inactive (100.03%)	inactive (>7943.28nM)	inactive (67%)
RSK4	inactive (107.77%)	-	inactive (123%)
RSK1	inactive (102.21%)	-	inactive (122%)
RSK3	inactive (94.2%)	-	inactive (115%)

AGC - PKA

Bioactivity
Kinase	RBC	Metz	Millipore
PKACg	inactive (90.73%)	-	-
PRKX	inactive (99.56%)	-	inactive (94%)
PKACa	inactive (103.95%)	inactive (>7943.28nM)	inactive (76%)

AGC - PKC

Bioactivity
Kinase	RBC	Metz	Millipore
PKCa	inactive (99.08%)	-	inactive (109%)
PKCd	inactive (91.13%)	inactive (>7943.28nM)	inactive (97%)
PKCe	inactive (100.07%)	-	inactive (88%)
PKCh	inactive (95.47%)	-	inactive (93%)
PKCg	inactive (97.23%)	inactive (>7943.28nM)	inactive (124%)
PKCi	inactive (96.4%)	-	inactive (84%)
PKCt	inactive (102.59%)	-	inactive (93%)
PKCz	inactive (104.38%)	inactive (>7943.28nM)	inactive (106%)
PKCb	inactive (99.78%)	-	-

AGC - PKG

Bioactivity
Kinase	RBC	Metz	Millipore
PKG2	inactive (98.62%)	-	-
PKG1	inactive (89.18%)	-	-

AGC - PKN

Bioactivity
Kinase	RBC	Metz	Millipore
PKN1	inactive (97.64%)	-	-
PKN2	inactive (96.13%)	inactive (>7943.28nM)	inactive (97%)

AGC - SGK

Bioactivity
Kinase	RBC	Metz	Millipore
SGK1	inactive (102.79%)	inactive (>10000nM)	inactive (79%)
SGK2	inactive (100.58%)	-	inactive (61%)
SGK3	inactive (102.08%)	-	inactive (108%)

AGC - NDR

Bioactivity
Kinase	RBC	Metz	Millipore
NDR1	inactive (99.09%)	-	-

TK

Test Member No. in Family
Family	no. Member on 518kinase	RBC	Metz	Millipore
Abl	2	2	1	2
Ack	2	1	1	1
ALK	2	2	2	1
Axl	3	3	2	3
Src	11	11	9	10
Tec	5	5	3	4
PDGFR	5	5	5	5
Csk	2	2	1	1
DDR	2	1	-	1
EGFR	4	3	3	2
Eph	14	12	1	11
FAK	2	2	2	2
Fer	2	2	2	2
FGFR	4	4	2	4
VEGFR	3	3	3	3
InsR	3	3	2	3
JakA	4	4	3	2
Musk	1	1	-	1
Ret	1	1	1	1
Met	2	2	2	2
Sev	1	1	1	1
Syk	2	2	1	2
Tie	2	1	-	1
Trk	3	3	3	2

TK - Abl

Bioactivity
Kinase	RBC	Metz	Millipore
ABL1	inactive (100.15%)	-	inactive (97%)
ABL2	inactive (93.43%)	-	inactive (105%)

TK - Ack

Bioactivity
Kinase	RBC	Metz	Millipore
ACK	inactive (98.29%)	-	inactive (88%)

TK - ALK

Bioactivity
Kinase	RBC	Metz	Millipore
ALK	inactive (105.32%)	-	inactive (94%)
LTK	inactive (91.35%)	-	-

TK - Axl

Bioactivity
Kinase	RBC	Metz	Millipore
AXL	inactive (95.08%)	active (1000nM)	inactive (95%)
MER	inactive (89.01%)	-	inactive (111%)
TYRO3	inactive (108.55%)	-	inactive (102%)

TK - Src

Bioactivity
Kinase	RBC	Metz	Millipore
BLK	inactive (95.62%)	-	inactive (104%)
BRK	inactive (86.7%)	-	inactive (115%)
SRC	inactive (94.81%)	-	inactive (87%)
FGR	inactive (93.67%)	-	inactive (110%)
FRK	inactive (97.39%)	-	inactive (97%)
FYN	inactive (116.25%)	-	inactive (96%)
HCK	inactive (97.53%)	-	inactive (78%)
LCK	inactive (95.74%)	-	inactive (132%)
SRM	inactive (104.13%)	-	-
YES	inactive (102.91%)	-	inactive (104%)
LYN	inactive (99.78%)	-	inactive (94%)

TK - Tec

Bioactivity
Kinase	RBC	Metz	Millipore
BMX	inactive (88.84%)	-	inactive (92%)
BTK	inactive (99.77%)	-	inactive (113%)
ITK	inactive (98.78%)	-	inactive (104%)
TEC	inactive (123.29%)	-	-
TXK	inactive (103.66%)	-	inactive (99%)

TK - PDGFR

Bioactivity
Kinase	RBC	Metz	Millipore
KIT	inactive (93.93%)	-	inactive (117%)
FLT3	inactive (92.77%)	-	inactive (99%)
FMS	inactive (99.96%)	-	inactive (67%)
PDGFRb	inactive (99.96%)	-	inactive (112%)
PDGFRa	inactive (109.59%)	-	inactive (122%)

TK - Csk

Bioactivity
Kinase	RBC	Metz	Millipore
CSK	inactive (100.71%)	-	inactive (118%)
CTK	inactive (86.29%)	-	-

TK - DDR

Bioactivity
Kinase	RBC	Metz	Millipore
DDR2	inactive (97.16%)	-	inactive (119%)

TK - EGFR

Bioactivity
Kinase	RBC	Metz	Millipore
EGFR	inactive (72.44%)	-	inactive (125%)
ErbB2	inactive (97.55%)	-	-
ErbB4	inactive (80.92%)	-	inactive (95%)

TK - Eph

Bioactivity
Kinase	RBC	Metz	Millipore
EphA1	inactive (99.39%)	-	inactive (90%)
EphA2	inactive (105.02%)	-	inactive (113%)
EphA3	inactive (97.21%)	-	inactive (107%)
EphA4	inactive (99.5%)	-	inactive (117%)
EphA5	inactive (103.28%)	-	inactive (101%)
EphA6	inactive (95.68%)	-	-
EphA7	inactive (89.7%)	-	inactive (104%)
EphA8	inactive (92.04%)	-	inactive (103%)
EphB1	inactive (87.43%)	-	inactive (96%)
EphB2	inactive (99.74%)	-	inactive (111%)
EphB3	inactive (101.47%)	-	inactive (111%)
EphB4	inactive (88.17%)	-	inactive (129%)

TK - FAK

Bioactivity
Kinase	RBC	Metz	Millipore
FAK	inactive (96.9%)	-	inactive (127%)
PYK2	inactive (92.59%)	-	inactive (146%)

TK - Fer

Bioactivity
Kinase	RBC	Metz	Millipore
FER	inactive (86.23%)	-	inactive (116%)
FES	inactive (100.93%)	-	inactive (124%)

TK - FGFR

Bioactivity
Kinase	RBC	Metz	Millipore
FGFR1	inactive (92.76%)	-	inactive (105%)
FGFR2	inactive (98.11%)	-	inactive (103%)
FGFR3	inactive (98.23%)	-	inactive (117%)
FGFR4	inactive (84.17%)	-	inactive (125%)

TK - VEGFR

Bioactivity
Kinase	RBC	Metz	Millipore
FLT1	inactive (88.01%)	-	inactive (98%)
FLT4	inactive (87.65%)	inactive (>6309.57nM)	inactive (95%)
KDR	inactive (95.84%)	inactive (>7943.28nM)	inactive (109%)

TK - InsR

Bioactivity
Kinase	RBC	Metz	Millipore
IGF1R	inactive (85.1%)	-	inactive (144%)
IRR	inactive (96.26%)	-	inactive (88%)
INSR	inactive (93.82%)	-	inactive (115%)

TK - JakA

Bioactivity
Kinase	RBC	Metz	Millipore
JAK1	inactive (93.83%)	-	-
JAK2	inactive (98.13%)	-	inactive (102%)
JAK3	inactive (97.17%)	-	inactive (107%)
TYK2	inactive (97.09%)	-	-

TK - Musk

Bioactivity
Kinase	RBC	Metz	Millipore
MUSK	inactive (97.93%)	-	inactive (105%)

TK - Ret

Bioactivity
Kinase	RBC	Metz	Millipore
RET	inactive (108.14%)	-	inactive (99%)

TK - Met

Bioactivity
Kinase	RBC	Metz	Millipore
RON	inactive (101.82%)	-	inactive (90%)
MET	inactive (98.14%)	-	inactive (103%)

TK - Sev

Bioactivity
Kinase	RBC	Metz	Millipore
ROS	inactive (101.33%)	-	inactive (91%)

TK - Syk

Bioactivity
Kinase	RBC	Metz	Millipore
SYK	inactive (115.93%)	-	inactive (127%)
ZAP70	inactive (101.01%)	-	inactive (117%)

TK - Tie

Bioactivity
Kinase	RBC	Metz	Millipore
TIE2	inactive (95.14%)	-	inactive (89%)

TK - Trk

Bioactivity
Kinase	RBC	Metz	Millipore
TRKA	inactive (98.36%)	-	inactive (64%)
TRKB	inactive (94.51%)	-	inactive (123%)
TRKC	inactive (98.77%)	-	-

TKL

Test Member No. in Family
Family	no. Member on 518kinase	RBC	Metz	Millipore
STKR	12	5	1	2
RAF	5	3	1	1
IRAK	4	2	2	2
LISK	4	1	1	1
LRRK	2	1	1	-
MLK	10	5	2	2
RIPK	5	1	-	1

TKL - STKR

Bioactivity
Kinase	RBC	Metz	Millipore
ALK1	inactive (105.97%)	-	-
ALK2	inactive (91.35%)	-	-
ALK4	inactive (97.98%)	-	inactive (139%)
TGFbR1	inactive (97.61%)	-	inactive (81%)
TGFbR2	inactive (110.58%)	-	-

TKL - RAF

Bioactivity
Kinase	RBC	Metz	Millipore
ARAF	inactive (95.22%)	-	-
BRAF	inactive (108.61%)	-	-
RAF1	inactive (92.76%)	-	inactive (82%)

TKL - IRAK

Bioactivity
Kinase	RBC	Metz	Millipore
IRAK1	inactive (154.12%)	inactive (3162.28nM)	inactive (93%)
IRAK4	inactive (93.71%)	inactive (>10000nM)	inactive (117%)

TKL - LISK

Bioactivity
Kinase	RBC	Metz	Millipore
LIMK1	inactive (97.03%)	inactive (>10000nM)	inactive (110%)

TKL - LRRK

Bioactivity
Kinase	RBC	Metz	Millipore
LRRK2	inactive (101.11%)	-	-

TKL - MLK

Bioactivity
Kinase	RBC	Metz	Millipore
MLK1	inactive (95.46%)	-	inactive (91%)
MLK2	inactive (100.22%)	-	-
MLK3	inactive (96.97%)	-	-
TAK1	inactive (98.11%)	-	inactive (94%)
ZAK	-	inactive (3162.28nM)	-

TKL - RIPK

Bioactivity
Kinase	RBC	Metz	Millipore
RIPK2	inactive (100.85%)	-	inactive (98%)

CAMK

Test Member No. in Family
Family	no. Member on 518kinase	RBC	Metz	Millipore
CAMKL	20	13	9	12
CAMK1	5	5	2	3
CAMK2	4	4	4	3
RAD53	1	1	1	1
DAPK	5	4	2	4
DCAMKL	3	1	1	1
MAPKAPK	5	5	4	4
MLCK	5	2	-	1
PHK	2	2	1	1
PIM	3	3	3	3
PKD	3	3	2	2
TSSK	5	2	2	2
STK33	1	-	1	-

CAMK - CAMKL

Bioactivity
Kinase	RBC	Metz	Millipore
NuaK1	inactive (89.97%)	-	inactive (100%)
BRSK1	inactive (104.5%)	inactive (>10000nM)	inactive (83%)
BRSK2	inactive (99.33%)	-	inactive (120%)
CHK1	inactive (89.24%)	inactive (>7943.28nM)	inactive (89%)
LKB1	inactive (97.37%)	-	inactive (102%)
MARK1	inactive (93.82%)	-	inactive (85%)
MARK3	inactive (97.53%)	inactive (>6309.57nM)	-
MARK4	inactive (104.35%)	-	-
MELK	inactive (100.34%)	-	inactive (80%)
PASK	inactive (95.1%)	-	inactive (100%)
QIK	inactive (99.7%)	-	-
NuaK2	inactive (130.57%)	-	-
MARK2	inactive (88.21%)	inactive (1258.93nM)	inactive (96%)
AMPKa1	-	inactive (1258.93nM)	inactive (87%)
AMPKa2	-	-	inactive (124%)
SIK	-	-	inactive (88%)

CAMK - CAMK1

Bioactivity
Kinase	RBC	Metz	Millipore
CaMK1a	inactive (93.01%)	inactive (>6309.57nM)	inactive (114%)
CaMK1b	inactive (97.07%)	-	-
CaMK1d	inactive (96.4%)	-	inactive (120%)
CaMK1g	inactive (98.66%)	-	-
CaMK4	inactive (96.97%)	-	inactive (121%)

CAMK - CAMK2

Bioactivity
Kinase	RBC	Metz	Millipore
CaMK2a	inactive (100.12%)	-	-
CaMK2b	inactive (102.29%)	inactive (>7943.28nM)	inactive (99%)
CaMK2d	inactive (103.59%)	inactive (>6309.57nM)	inactive (110%)
CaMK2g	inactive (94.09%)	inactive (>6309.57nM)	inactive (111%)

CAMK - RAD53

Bioactivity
Kinase	RBC	Metz	Millipore
CHK2	inactive (97.53%)	-	inactive (89%)

CAMK - DAPK

Bioactivity
Kinase	RBC	Metz	Millipore
DAPK1	inactive (99.73%)	-	inactive (97%)
DAPK2	inactive (98.48%)	-	inactive (91%)
DRAK1	inactive (98.84%)	-	inactive (105%)
DAPK3	inactive (86.47%)	-	inactive (89%)

CAMK - DCAMKL

Bioactivity
Kinase	RBC	Metz	Millipore
DCLK2	inactive (101.12%)	-	inactive (69%)
DCLK1	-	inactive (>10000nM)	-

CAMK - MAPKAPK

Bioactivity
Kinase	RBC	Metz	Millipore
MAPKAPK2	inactive (101.36%)	inactive (5011.87nM)	inactive (85%)
MAPKAPK3	inactive (102.32%)	inactive (>10000nM)	inactive (110%)
MAPKAPK5	inactive (94.21%)	-	inactive (72%)
MNK1	inactive (77.82%)	-	-
MNK2	inactive (87.95%)	inactive (3162.28nM)	inactive (114%)

CAMK - MLCK

Bioactivity
Kinase	RBC	Metz	Millipore
smMLCK	inactive (94.45%)	-	inactive (101%)
skMLCK	inactive (97.94%)	-	-

CAMK - PHK

Bioactivity
Kinase	RBC	Metz	Millipore
PHKg1	inactive (92.62%)	-	-
PHKg2	inactive (96.01%)	-	inactive (93%)

CAMK - PIM

Bioactivity
Kinase	RBC	Metz	Millipore
PIM1	inactive (107.94%)	inactive (7943.28nM)	inactive (74%)
PIM2	inactive (97.09%)	-	inactive (112%)
PIM3	inactive (95.76%)	inactive (>7943.28nM)	inactive (98%)

CAMK - PKD

Bioactivity
Kinase	RBC	Metz	Millipore
PKD1	inactive (92.45%)	-	inactive (108%)
PKD3	inactive (90.17%)	inactive (>10000nM)	-
PKD2	inactive (100.93%)	inactive (6309.57nM)	inactive (94%)

CAMK - TSSK

Bioactivity
Kinase	RBC	Metz	Millipore
TSSK1	inactive (90.17%)	-	inactive (97%)
TSSK2	inactive (89.97%)	-	inactive (86%)

CAMK - STK33

Bioactivity
Kinase	RBC	Metz	Millipore
STK33	inactive (94.91%)	-	inactive (93%)

STE

Test Member No. in Family
Family	no. Member on 518kinase	RBC	Metz	Millipore
STE11	8	3	-	1
STE-Unique	2	2	-	-
STE20	31	23	9	14
STE7	7	3	2	3

STE - STE11

Bioactivity
Kinase	RBC	Metz	Millipore
MAP3K5	inactive (103.73%)	-	inactive (91%)
MAP3K2	inactive (99.77%)	-	-
MAP3K3	inactive (101.89%)	-	-

STE - STE-Unique

Bioactivity
Kinase	RBC	Metz	Millipore
COT	inactive (98.12%)	-	-
NIK	inactive (109.06%)	-	-

STE - STE20

Bioactivity
Kinase	RBC	Metz	Millipore
GCK	inactive (103.27%)	inactive (1995.26nM)	inactive (97%)
HGK	inactive (95%)	inactive (>7943.28nM)	-
KHS1	inactive (93.74%)	inactive (1995.26nM)	-
LOK	inactive (89.59%)	-	inactive (94%)
MINK	inactive (97.91%)	inactive (3162.28nM)	inactive (113%)
MST1	inactive (95.95%)	-	inactive (106%)
MST2	inactive (106.61%)	inactive (>7943.28nM)	inactive (107%)
MST3	inactive (100.43%)	-	inactive (82%)
MST4	inactive (102.61%)	-	-
OSR1	inactive (101.19%)	-	-
PAK1	inactive (97.71%)	inactive (>10000nM)	-
PAK2	inactive (76.84%)	-	inactive (103%)
PAK3	inactive (100.93%)	-	inactive (89%)
PAK4	inactive (111.17%)	-	inactive (92%)
PAK5	inactive (96.11%)	-	inactive (96%)
PAK6	inactive (99.4%)	-	inactive (93%)
SLK	inactive (99.09%)	inactive (3981.07nM)	-
YSK1	inactive (100.6%)	-	-
STLK3	inactive (99.84%)	-	-
TAO1	inactive (95.1%)	inactive (3981.07nM)	inactive (108%)
TAO2	inactive (95.74%)	-	inactive (111%)
TAO3	inactive (102.83%)	-	inactive (106%)
MYO3B	inactive (88.3%)	-	-

STE - STE7

Bioactivity
Kinase	RBC	Metz	Millipore
MAP2K1	inactive (94.02%)	-	inactive (98%)
MAP2K2	inactive (104.69%)	-	-
MAP2K6	inactive (126.52%)	-	inactive (89%)
MAP2K7	-	-	inactive (83%)

Other

Test Member No. in Family
Family	no. Member on 518kinase	RBC	Metz	Millipore
Aur	3	3	2	3
CAMKK	2	2	1	-
Haspin	1	1	-	1
IKK	4	4	4	3
NEK	11	8	2	5
TOPK	1	1	1	-
PLK	4	3	3	3
SgK496	1	1	-	-
NAK	4	1	-	-
TTK	1	1	-	-
ULK	5	3	-	2
WEE	3	1	1	-
WNK	4	2	-	2
TLK	2	1	-	1
CDC7	1	-	1	-

Other - Aur

Bioactivity
Kinase	RBC	Metz	Millipore
AurA	inactive (92.24%)	-	inactive (95%)
AurB	inactive (94.4%)	active (630.96nM)	inactive (108%)
AurC	inactive (95.54%)	-	inactive (99%)

Other - CAMKK

Bioactivity
Kinase	RBC	Metz	Millipore
CaMKK1	inactive (102.14%)	-	-
CaMKK2	inactive (97.36%)	-	-

Other - Haspin

Bioactivity
Kinase	RBC	Metz	Millipore
Haspin	inactive (104.03%)	-	inactive (83%)

Other - IKK

Bioactivity
Kinase	RBC	Metz	Millipore
IKKa	inactive (103.25%)	-	inactive (104%)
IKKb	inactive (102.99%)	-	inactive (113%)
IKKe	inactive (105.48%)	-	-
TBK1	inactive (98.27%)	-	inactive (82%)

Other - NEK

Bioactivity
Kinase	RBC	Metz	Millipore
NEK1	inactive (97.26%)	-	-
NEK11	inactive (95.45%)	-	inactive (103%)
NEK2	inactive (102.31%)	inactive (>10000nM)	inactive (83%)
NEK4	inactive (98.59%)	-	-
NEK6	inactive (103.81%)	-	inactive (94%)
NEK7	inactive (111.45%)	-	inactive (101%)
NEK9	inactive (97.16%)	-	-
NEK3	inactive (95.11%)	-	inactive (114%)

Other - TOPK

Bioactivity
Kinase	RBC	Metz	Millipore
PBK	inactive (84.17%)	inactive (>10000nM)	-

Other - PLK

Bioactivity
Kinase	RBC	Metz	Millipore
PLK1	inactive (97.29%)	inactive (3162.28nM)	inactive (86%)
PLK2	inactive (104.73%)	-	inactive (100%)
PLK3	inactive (96.07%)	active (630.96nM)	inactive (94%)
PLK4	-	active (630.96nM)	-

Other - SgK496

Bioactivity
Kinase	RBC	Metz	Millipore
SgK496	inactive (91.04%)	-	-

Other - NAK

Bioactivity
Kinase	RBC	Metz	Millipore
MPSK1	inactive (99.11%)	-	-

Other - TTK

Bioactivity
Kinase	RBC	Metz	Millipore
TTK	inactive (102.63%)	-	-

Other - ULK

Bioactivity
Kinase	RBC	Metz	Millipore
ULK1	inactive (92.89%)	-	-
ULK2	inactive (106.4%)	-	inactive (109%)
ULK3	inactive (71.21%)	-	inactive (108%)

Other - WEE

Bioactivity
Kinase	RBC	Metz	Millipore
Wee1	inactive (89.93%)	-	-

Other - WNK

Bioactivity
Kinase	RBC	Metz	Millipore
Wnk2	inactive (103.73%)	-	inactive (110%)
Wnk3	inactive (95%)	-	inactive (106%)

Other - TLK

Bioactivity
Kinase	RBC	Metz	Millipore
TLK2	inactive (105.39%)	-	inactive (96%)

Other - CDC7

Bioactivity
Kinase	RBC	Metz	Millipore
CDC7	-	-	-

CK1

Test Member No. in Family
Family	no. Member on 518kinase	RBC	Metz	Millipore
CK1	7	6	5	4
VRK	3	1	-	1

CK1 - CK1

Bioactivity
Kinase	RBC	Metz	Millipore
CK1d	inactive (98.34%)	inactive (>7943.28nM)	inactive (80%)
CK1g1	inactive (101.98%)	-	inactive (91%)
CK1g2	inactive (105.91%)	inactive (>7943.28nM)	inactive (95%)
CK1g3	inactive (104.49%)	-	inactive (109%)
CK1a	inactive (109.67%)	inactive (>6309.57nM)	-
CK1e	inactive (86.27%)	-	-

CK1 - VRK

Bioactivity
Kinase	RBC	Metz	Millipore
VRK1	inactive (96.98%)	-	-
VRK2	-	-	inactive (96%)

CMGC

Test Member No. in Family
Family	no. Member on 518kinase	RBC	Metz	Millipore
CK2	3	2	1	2
CLK	4	4	2	2
DYRK	10	9	6	4
MAPK	14	10	8	10
GSK	2	2	2	2
SRPK	3	3	1	3
CDK	20	-	7	-

CMGC - CK2

Bioactivity
Kinase	RBC	Metz	Millipore
CK2a1	inactive (86.61%)	inactive (>6309.57nM)	inactive (88%)
CK2a2	inactive (81.87%)	-	inactive (129%)

CMGC - CLK

Bioactivity
Kinase	RBC	Metz	Millipore
CLK1	inactive (98.55%)	-	-
CLK2	inactive (109.58%)	inactive (>7943.28nM)	inactive (115%)
CLK3	inactive (125.05%)	-	inactive (82%)
CLK4	inactive (93.96%)	inactive (>6309.57nM)	-

CMGC - DYRK

Bioactivity
Kinase	RBC	Metz	Millipore
DYRK1A	inactive (101.51%)	inactive (>6309.57nM)	-
DYRK1B	inactive (106.4%)	-	-
DYRK2	inactive (102.81%)	-	inactive (87%)
DYRK3	inactive (99.57%)	inactive (>6309.57nM)	-
DYRK4	inactive (106.18%)	inactive (>7943.28nM)	-
HIPK1	inactive (100.99%)	-	inactive (93%)
HIPK2	inactive (101.34%)	-	inactive (101%)
HIPK3	inactive (96.55%)	-	inactive (105%)
HIPK4	inactive (106.12%)	inactive (2511.89nM)	-

CMGC - MAPK

Bioactivity
Kinase	RBC	Metz	Millipore
Erk1	inactive (106.09%)	-	inactive (77%)
Erk2	inactive (92.21%)	-	inactive (110%)
JNK3	inactive (97.97%)	-	inactive (94%)
NLK	inactive (110.25%)	-	inactive (101%)
p38a	inactive (108.4%)	-	inactive (72%)
p38b	inactive (98.72%)	-	inactive (106%)
p38d	inactive (101.44%)	inactive (>7943.28nM)	inactive (125%)
p38g	inactive (94.18%)	inactive (>6309.57nM)	inactive (115%)
JNK1	inactive (99.09%)	-	inactive (112%)
JNK2	inactive (103.44%)	-	inactive (108%)

CMGC - GSK

Bioactivity
Kinase	RBC	Metz	Millipore
GSK3A	inactive (96.54%)	inactive (2511.89nM)	inactive (107%)
GSK3B	inactive (105.97%)	inactive (1258.93nM)	inactive (95%)

CMGC - SRPK

Bioactivity
Kinase	RBC	Metz	Millipore
MSSK1	inactive (93.91%)	-	inactive (109%)
SRPK1	inactive (104.27%)	-	inactive (100%)
SRPK2	inactive (96.64%)	-	inactive (96%)

CMGC - CDK

Bioactivity
Kinase	RBC	Metz	Millipore
CDC2	-	inactive (>7943.28nM)	-
CDK2	-	inactive (>7943.28nM)	-
CDK5	-	inactive (>10000nM)	-
CDK8	-	-	-
CDK7	-	-	-
CDK9	-	-	-
CDK11	-	-	-

Atypical

Test Member No. in Family
Family	no. Member on 518kinase	RBC	Metz	Millipore
PDHK	5	1	-	-
Alpha	6	-	1	1
PIKK	6	-	-	1

Atypical - PDHK

Bioactivity
Kinase	RBC	Metz	Millipore
PDHK1	inactive (73.99%)	-	-

Atypical - Alpha

Bioactivity
Kinase	RBC	Metz	Millipore
eEF2K	-	inactive (1995.26nM)	inactive (83%)

Atypical - PIKK

Bioactivity
Kinase	RBC	Metz	Millipore
FRAP	-	-	inactive (110%)