Compound Information


Test on : DRx, RBC, Metz

Compound Name
DRx, RBC, Metz : Vatalanib

Inchikey
Same : YCOYDOIWSSHVCK-N
DRx, RBC, Metz : YCOYDOIWSSHVCK-UHFFFAOYSA-N

ChemSpider
DRx, RBC, Metz : 133257

Pubchem CID
DRx, RBC, Metz : 151194

ChEMBL
DRx, RBC, Metz : CHEMBL101253




DRx RBC Metz Millipore GPCR
bioactivity Kd (nM) Remain Activity (%) Ki (nM) Remain Activity (%) Inhibition (%)
active criteria <3000nM <50% <1000nM <50% >50%

Other


Test Member No. in Family
Familyno. Member on 518kinaseDRxRBCMetz
441-
3332
2221
42--
21--
4444
11982
3311
4433
111-
32--
21--
543-
221-
111-
1-1-
1-11
4-2-
1--1
Other - NAK

Bioactivity
KinaseDRxRBCMetz
AAK1inactive (10001nM)--
BIKEinactive (10001nM)--
GAKinactive (10001nM)--
MPSK1inactive (10001nM)inactive (93.51%)-
Other - Aur

Bioactivity
KinaseDRxRBCMetz
AurAinactive (10001nM)inactive (78.98%)inactive (>2511.89nM)
AurBinactive (10001nM)inactive (89.99%)inactive (>3162.28nM)
AurCinactive (10001nM)inactive (86.99%)-
Other - CAMKK

Bioactivity
KinaseDRxRBCMetz
CaMKK1inactive (10001nM)inactive (97.15%)-
CaMKK2inactive (10001nM)inactive (100.41%)-
Other - PEK

Bioactivity
KinaseDRxRBCMetz
HRIinactive (10001nM)--
PKRinactive (10001nM)--
Other - IRE

Bioactivity
KinaseDRxRBCMetz
IRE1inactive (10001nM)--
Other - IKK

Bioactivity
KinaseDRxRBCMetz
IKKainactive (10001nM)inactive (104.3%)inactive (>3981.07nM)
IKKbinactive (10001nM)inactive (85.61%)inactive (>3162.28nM)
IKKeinactive (10001nM)inactive (95.71%)inactive (>3162.28nM)
TBK1inactive (10001nM)inactive (103.55%)inactive (>3162.28nM)
Other - NEK

Bioactivity
KinaseDRxRBCMetz
NEK1inactive (10001nM)inactive (75.26%)-
NEK11inactive (10001nM)inactive (86.96%)-
NEK2inactive (10001nM)inactive (101.38%)inactive (>6309.57nM)
NEK3inactive (10001nM)inactive (94.08%)-
NEK4inactive (10001nM)inactive (97.65%)inactive (>6309.57nM)
NEK5inactive (10001nM)--
NEK6inactive (10001nM)inactive (93.27%)-
NEK7inactive (10001nM)inactive (96.76%)-
NEK9inactive (10001nM)inactive (98.41%)-
Other - WEE

Bioactivity
KinaseDRxRBCMetz
MYT1inactive (10001nM)--
Wee1inactive (10001nM)inactive (108.52%)-
Wee1Binactive (10001nM)--
Other - PLK

Bioactivity
KinaseDRxRBCMetz
PLK1inactive (10001nM)inactive (95.91%)inactive (>7943.28nM)
PLK2inactive (10001nM)inactive (100.77%)-
PLK3inactive (10001nM)inactive (100.26%)inactive (>7943.28nM)
PLK4inactive (10001nM)-inactive (>3981.07nM)
Other - SgK496

Bioactivity
KinaseDRxRBCMetz
SgK496inactive (10001nM)inactive (96.5%)-
Other - NKF1

Bioactivity
KinaseDRxRBCMetz
SBKinactive (10001nM)--
SgK110inactive (10001nM)--
Other - NKF4

Bioactivity
KinaseDRxRBCMetz
CLIK1inactive (10001nM)--
Other - ULK

Bioactivity
KinaseDRxRBCMetz
Fusedinactive (10001nM)--
ULK1inactive (10001nM)inactive (106.51%)-
ULK2inactive (10001nM)inactive (99.95%)-
ULK3inactive (10001nM)inactive (101.34%)-
Other - TLK

Bioactivity
KinaseDRxRBCMetz
TLK1inactive (10001nM)--
TLK2inactive (10001nM)inactive (102.21%)-
Other - TTK

Bioactivity
KinaseDRxRBCMetz
TTKinactive (10001nM)inactive (107.78%)-
Other - Haspin

Bioactivity
KinaseDRxRBCMetz
Haspin-inactive (70.03%)-
Other - TOPK

Bioactivity
KinaseDRxRBCMetz
PBK-inactive (108.07%)inactive (>10000nM)
Other - WNK

Bioactivity
KinaseDRxRBCMetz
Wnk2-inactive (96.31%)-
Wnk3-inactive (99.12%)-
Other - CDC7

Bioactivity
KinaseDRxRBCMetz
CDC7--inactive (>1258.93nM)

TK


Test Member No. in Family
Familyno. Member on 518kinaseDRxRBCMetz
2221
2222
3332
1111119
5553
5555
2221
221-
4433
1413121
2222
2222
4442
3333
3332
4443
2222
111-
1111
1111
2221
221-
2211
3333
TK - Abl

Bioactivity
KinaseDRxRBCMetz
ABL1inactive (10001nM)inactive (96.52%)inactive (>1584.89nM)
ABL2inactive (10001nM)inactive (100.63%)-
TK - ALK

Bioactivity
KinaseDRxRBCMetz
ALKinactive (10001nM)inactive (101.78%)inactive (>3981.07nM)
LTKinactive (10001nM)inactive (105.24%)inactive (>2511.89nM)
TK - Axl

Bioactivity
KinaseDRxRBCMetz
AXLinactive (10001nM)inactive (98.33%)inactive (>1995.26nM)
MERinactive (10001nM)inactive (116.05%)-
TYRO3inactive (10001nM)inactive (98.17%)inactive (>2511.89nM)
TK - Src

Bioactivity
KinaseDRxRBCMetz
BLKinactive (10001nM)inactive (105.08%)inactive (>1584.89nM)
BRKactive (2400nM)inactive (89.15%)inactive (>2511.89nM)
FGRinactive (10001nM)inactive (96.78%)-
FRKactive (1800nM)inactive (95.39%)active (316.23nM)
FYNinactive (10001nM)inactive (104.31%)inactive (>3162.28nM)
HCKinactive (10001nM)inactive (89.54%)-
LCKinactive (10001nM)inactive (86.99%)inactive (>5011.87nM)
LYNinactive (10001nM)inactive (91.83%)inactive (>1584.89nM)
SRCinactive (10001nM)inactive (103.5%)inactive (>5011.87nM)
SRMinactive (10001nM)inactive (91.75%)inactive (>1584.89nM)
YESinactive (10001nM)inactive (93%)-
TK - Tec

Bioactivity
KinaseDRxRBCMetz
BMXinactive (10001nM)inactive (105.86%)-
BTKinactive (10001nM)inactive (95.36%)inactive (>3981.07nM)
ITKinactive (10001nM)inactive (103.24%)inactive (>1584.89nM)
TECinactive (10001nM)inactive (136.58%)-
TXKinactive (10001nM)inactive (110.29%)-
TK - PDGFR

Bioactivity
KinaseDRxRBCMetz
FMSactive (45nM)active (33.5%)active (1000nM)
FLT3inactive (10001nM)inactive (91.99%)inactive (>2511.89nM)
KITactive (5.1nM)active (45.66%)active (39.81nM)
PDGFRaactive (96nM)active (33.28%)inactive (1258.93nM)
PDGFRbactive (25nM)inactive (65.62%)active (79.43nM)
TK - Csk

Bioactivity
KinaseDRxRBCMetz
CSKinactive (10001nM)inactive (87.62%)-
CTKinactive (10001nM)inactive (78.12%)inactive (>1995.26nM)
TK - DDR

Bioactivity
KinaseDRxRBCMetz
DDR1active (270nM)--
DDR2inactive (10001nM)inactive (97.09%)-
TK - EGFR

Bioactivity
KinaseDRxRBCMetz
EGFRinactive (10001nM)inactive (95.76%)inactive (>1995.26nM)
ErbB2inactive (10001nM)inactive (100.57%)inactive (>1584.89nM)
ErbB3inactive (10001nM)--
ErbB4inactive (10001nM)inactive (103.74%)inactive (>3981.07nM)
TK - Eph

Bioactivity
KinaseDRxRBCMetz
EphA1inactive (10001nM)inactive (96.03%)-
EphA2inactive (10001nM)inactive (92.51%)inactive (>7943.28nM)
EphA3inactive (10001nM)inactive (98.82%)-
EphA4inactive (10001nM)inactive (102.29%)-
EphA5inactive (10001nM)inactive (108.77%)-
EphA6inactive (10001nM)inactive (100.99%)-
EphA7inactive (10001nM)inactive (90.52%)-
EphA8inactive (10001nM)inactive (100.34%)-
EphB1inactive (10001nM)inactive (106.78%)-
EphB2inactive (10001nM)inactive (106.86%)-
EphB3inactive (10001nM)inactive (65.11%)-
EphB4inactive (10001nM)inactive (85.09%)-
EphB6inactive (10001nM)--
TK - FAK

Bioactivity
KinaseDRxRBCMetz
FAKinactive (10001nM)inactive (100.74%)inactive (>3981.07nM)
PYK2inactive (10001nM)inactive (102.31%)inactive (>1584.89nM)
TK - Fer

Bioactivity
KinaseDRxRBCMetz
FERinactive (10001nM)inactive (91.35%)inactive (>1584.89nM)
FESinactive (10001nM)inactive (94.65%)inactive (>1995.26nM)
TK - FGFR

Bioactivity
KinaseDRxRBCMetz
FGFR1inactive (10001nM)inactive (97.15%)inactive (>3981.07nM)
FGFR2inactive (10001nM)inactive (96.03%)-
FGFR3inactive (10001nM)inactive (91.54%)inactive (>1995.26nM)
FGFR4inactive (10001nM)inactive (95.78%)-
TK - VEGFR

Bioactivity
KinaseDRxRBCMetz
FLT1active (9.6nM)inactive (59.42%)active (158.49nM)
FLT4active (330nM)inactive (62.81%)active (316.23nM)
KDRactive (62nM)active (40.28%)active (12.59nM)
TK - InsR

Bioactivity
KinaseDRxRBCMetz
IGF1Rinactive (10001nM)inactive (108.48%)inactive (>1995.26nM)
INSRinactive (10001nM)inactive (99.86%)inactive (>5011.87nM)
IRRinactive (10001nM)inactive (93.49%)-
TK - JakA

Bioactivity
KinaseDRxRBCMetz
JAK1inactive (10001nM)inactive (107.36%)-
JAK2inactive (10001nM)inactive (105.8%)inactive (>1995.26nM)
JAK3inactive (10001nM)inactive (92.09%)inactive (>3981.07nM)
TYK2inactive (10001nM)inactive (89.43%)inactive (>1995.26nM)
TK - Met

Bioactivity
KinaseDRxRBCMetz
METinactive (10001nM)inactive (94.05%)inactive (>2511.89nM)
RONinactive (10001nM)inactive (91.6%)inactive (>3981.07nM)
TK - Musk

Bioactivity
KinaseDRxRBCMetz
MUSKinactive (10001nM)inactive (105.28%)-
TK - Ret

Bioactivity
KinaseDRxRBCMetz
RETinactive (10001nM)inactive (89.11%)inactive (>2511.89nM)
TK - Sev

Bioactivity
KinaseDRxRBCMetz
ROSinactive (10001nM)inactive (94.74%)inactive (>1995.26nM)
TK - Syk

Bioactivity
KinaseDRxRBCMetz
SYKinactive (10001nM)inactive (114.23%)inactive (>1584.89nM)
ZAP70inactive (10001nM)inactive (96.63%)-
TK - Tie

Bioactivity
KinaseDRxRBCMetz
TIE1inactive (10001nM)--
TIE2inactive (10001nM)inactive (97.5%)-
TK - Ack

Bioactivity
KinaseDRxRBCMetz
TNK1inactive (10001nM)--
ACKinactive (10001nM)inactive (91.66%)inactive (>3981.07nM)
TK - Trk

Bioactivity
KinaseDRxRBCMetz
TRKAinactive (10001nM)inactive (98.72%)inactive (>2511.89nM)
TRKBinactive (10001nM)inactive (102.35%)inactive (>3981.07nM)
TRKCinactive (10001nM)inactive (92.75%)inactive (>2511.89nM)

TKL


Test Member No. in Family
Familyno. Member on 518kinaseDRxRBCMetz
121051
541-
5231
10852
4322
4311
2111
TKL - STKR

Bioactivity
KinaseDRxRBCMetz
ALK2inactive (10001nM)inactive (96.09%)inactive (>3981.07nM)
ALK4inactive (10001nM)inactive (108.49%)-
ACTR2inactive (10001nM)--
ACTR2Binactive (10001nM)--
ALK1inactive (10001nM)inactive (98.52%)-
BMPR1Ainactive (10001nM)--
BMPR1Binactive (10001nM)--
BMPR2inactive (10001nM)--
TGFbR1inactive (10001nM)inactive (96.77%)-
TGFbR2inactive (10001nM)inactive (100.48%)-
TKL - RIPK

Bioactivity
KinaseDRxRBCMetz
SgK288inactive (10001nM)--
RIPK1inactive (10001nM)--
RIPK2inactive (10001nM)inactive (110.71%)-
ANKRD3inactive (10001nM)--
TKL - RAF

Bioactivity
KinaseDRxRBCMetz
BRAFinactive (10001nM)inactive (92.18%)-
RAF1inactive (10001nM)inactive (93.29%)-
ARAF-inactive (97.64%)-
TKL - MLK

Bioactivity
KinaseDRxRBCMetz
DLKinactive (10001nM)--
LZKinactive (10001nM)--
MLK1inactive (10001nM)inactive (113.41%)-
MLK2inactive (10001nM)inactive (109.68%)-
MLK3inactive (10001nM)inactive (105.85%)-
TAK1inactive (10001nM)inactive (99.61%)-
HH498inactive (10001nM)--
ZAKinactive (4400nM)inactive (90.34%)inactive (>7943.28nM)
TKL - IRAK

Bioactivity
KinaseDRxRBCMetz
IRAK1inactive (10001nM)inactive (94.12%)inactive (>7943.28nM)
IRAK3inactive (10001nM)--
IRAK4inactive (10001nM)inactive (85.13%)inactive (>10000nM)
TKL - LISK

Bioactivity
KinaseDRxRBCMetz
LIMK1inactive (10001nM)inactive (98.94%)inactive (>6309.57nM)
LIMK2inactive (10001nM)--
TESK1inactive (10001nM)--
TKL - LRRK

Bioactivity
KinaseDRxRBCMetz
LRRK2inactive (10001nM)inactive (74.77%)inactive (>2511.89nM)

Atypical


Test Member No. in Family
Familyno. Member on 518kinaseDRxRBCMetz
52--
61--
33--
61-1
5-1-
Atypical - ABC1

Bioactivity
KinaseDRxRBCMetz
ADCK3inactive (10001nM)--
ADCK4inactive (10001nM)--
Atypical - PIKK

Bioactivity
KinaseDRxRBCMetz
FRAPinactive (10001nM)--
Atypical - RIO

Bioactivity
KinaseDRxRBCMetz
RIOK1inactive (10001nM)--
RIOK2inactive (10001nM)--
RIOK3inactive (10001nM)--
Atypical - Alpha

Bioactivity
KinaseDRxRBCMetz
ChaK2inactive (10001nM)--
eEF2K--inactive (>3981.07nM)
Atypical - PDHK

Bioactivity
KinaseDRxRBCMetz
PDHK1-inactive (88.27%)-

AGC


Test Member No. in Family
Familyno. Member on 518kinaseDRxRBCMetz
3333
7753
7361
441-
51--
1111
5332
3221
9595
2232
8184
3131
33--
AGC - Akt

Bioactivity
KinaseDRxRBCMetz
AKT1inactive (10001nM)inactive (102.97%)inactive (>7943.28nM)
AKT2inactive (10001nM)inactive (103.99%)inactive (>7943.28nM)
AKT3inactive (10001nM)inactive (89.9%)inactive (>10000nM)
AGC - DMPK

Bioactivity
KinaseDRxRBCMetz
CRIKinactive (8800nM)--
DMPK1inactive (10001nM)inactive (102.15%)-
DMPK2inactive (10001nM)--
MRCKainactive (10001nM)inactive (78.31%)inactive (>10000nM)
MRCKbinactive (10001nM)inactive (99.54%)-
ROCK1inactive (10001nM)inactive (110.26%)inactive (>6309.57nM)
ROCK2inactive (10001nM)inactive (95.41%)inactive (>3981.07nM)
AGC - GRK

Bioactivity
KinaseDRxRBCMetz
RHOKinactive (10001nM)--
GPRK4inactive (10001nM)inactive (91.28%)-
GPRK7inactive (10001nM)inactive (92.2%)-
BARK1-inactive (102.15%)-
BARK2-inactive (92.91%)-
GPRK5-inactive (109.94%)inactive (>3981.07nM)
GPRK6-inactive (99.91%)-
AGC - NDR

Bioactivity
KinaseDRxRBCMetz
LATS1inactive (10001nM)--
LATS2inactive (10001nM)--
NDR1inactive (10001nM)inactive (100.28%)-
NDR2inactive (10001nM)--
AGC - MAST

Bioactivity
KinaseDRxRBCMetz
MAST1inactive (10001nM)--
AGC - PDK1

Bioactivity
KinaseDRxRBCMetz
PDK1inactive (10001nM)inactive (88.27%)inactive (>3981.07nM)
AGC - PKA

Bioactivity
KinaseDRxRBCMetz
PKACainactive (10001nM)inactive (98.12%)inactive (>3162.28nM)
PKACbinactive (10001nM)--
PRKXinactive (10001nM)inactive (151.85%)inactive (>2511.89nM)
PKACg-inactive (115.51%)-
AGC - PKN

Bioactivity
KinaseDRxRBCMetz
PKN1inactive (10001nM)inactive (95.86%)-
PKN2inactive (10001nM)inactive (99.91%)inactive (>7943.28nM)
AGC - PKC

Bioactivity
KinaseDRxRBCMetz
PKCdinactive (10001nM)inactive (97.35%)inactive (>7943.28nM)
PKCeinactive (10001nM)inactive (100.03%)-
PKChinactive (10001nM)inactive (105.3%)-
PKCiinactive (10001nM)inactive (94.17%)-
PKCtinactive (10001nM)inactive (73.46%)inactive (>2511.89nM)
PKCa-inactive (75.84%)-
PKCg-inactive (93.33%)inactive (>7943.28nM)
PKCz-inactive (69.54%)inactive (>7943.28nM)
PKCb-inactive (97.17%)-
AGC - PKG

Bioactivity
KinaseDRxRBCMetz
PKG1inactive (10001nM)inactive (97.23%)inactive (>1995.26nM)
PKG2inactive (10001nM)inactive (101.47%)inactive (>1584.89nM)
AGC - RSK

Bioactivity
KinaseDRxRBCMetz
p70S6Kinactive (10001nM)inactive (101.84%)inactive (3162.28nM)
MSK1-inactive (85.51%)inactive (>1995.26nM)
MSK2-inactive (98.03%)-
p70S6Kb-inactive (101.4%)-
RSK2-inactive (100.79%)inactive (>3981.07nM)
RSK4-inactive (99.69%)-
RSK1-inactive (112.84%)-
RSK3-inactive (97.5%)-
AGC - SGK

Bioactivity
KinaseDRxRBCMetz
SGK3inactive (10001nM)inactive (99.19%)-
SGK1-inactive (121%)inactive (>10000nM)
SGK2-inactive (103.78%)-
AGC - YANK

Bioactivity
KinaseDRxRBCMetz
YANK1inactive (10001nM)--
YANK2inactive (10001nM)--
YANK3inactive (10001nM)--

CAMK


Test Member No. in Family
Familyno. Member on 518kinaseDRxRBCMetz
2019139
5452
4444
11--
1111
5542
3311
5454
542-
2221
3333
3332
11-1
5122
CAMK - CAMKL

Bioactivity
KinaseDRxRBCMetz
AMPKa1inactive (10001nM)-inactive (>5011.87nM)
AMPKa2inactive (10001nM)--
NuaK1inactive (10001nM)inactive (111.52%)-
BRSK1inactive (10001nM)inactive (93.09%)inactive (>10000nM)
BRSK2inactive (10001nM)inactive (97.07%)-
CHK1inactive (10001nM)inactive (96.5%)inactive (>6309.57nM)
HUNKinactive (10001nM)--
LKB1inactive (10001nM)inactive (97.3%)-
MARK1inactive (10001nM)inactive (124%)-
MARK2inactive (10001nM)inactive (133.32%)inactive (>7943.28nM)
MARK3inactive (10001nM)inactive (102.46%)inactive (>6309.57nM)
MARK4inactive (10001nM)inactive (104.48%)-
MELKinactive (10001nM)inactive (83.72%)inactive (>1584.89nM)
NIM1inactive (10001nM)--
QSKinactive (10001nM)--
SIKinactive (10001nM)--
QIKinactive (10001nM)inactive (97.91%)-
NuaK2inactive (10001nM)inactive (105.11%)-
SNRKinactive (10001nM)--
PASK-inactive (101.26%)-
CAMK - CAMK1

Bioactivity
KinaseDRxRBCMetz
CaMK1ainactive (10001nM)inactive (100.1%)inactive (>6309.57nM)
CaMK1dinactive (10001nM)inactive (107.76%)inactive (>2511.89nM)
CaMK1ginactive (10001nM)inactive (107.27%)-
CaMK4inactive (10001nM)inactive (93.43%)-
CaMK1b-inactive (103.49%)-
CAMK - CAMK2

Bioactivity
KinaseDRxRBCMetz
CaMK2ainactive (10001nM)inactive (93.23%)inactive (>6309.57nM)
CaMK2binactive (10001nM)inactive (108.74%)inactive (>7943.28nM)
CaMK2dinactive (10001nM)inactive (81.05%)inactive (>6309.57nM)
CaMK2ginactive (10001nM)inactive (114.99%)inactive (>6309.57nM)
CAMK - CASK

Bioactivity
KinaseDRxRBCMetz
CASKinactive (10001nM)--
CAMK - RAD53

Bioactivity
KinaseDRxRBCMetz
CHK2inactive (10001nM)inactive (98.49%)inactive (>5011.87nM)
CAMK - DAPK

Bioactivity
KinaseDRxRBCMetz
DAPK1inactive (10001nM)inactive (105.2%)-
DAPK2inactive (10001nM)inactive (91.67%)-
DAPK3inactive (10001nM)inactive (107.09%)inactive (>3162.28nM)
DRAK1inactive (10001nM)inactive (99.4%)inactive (>3981.07nM)
DRAK2inactive (10001nM)--
CAMK - DCAMKL

Bioactivity
KinaseDRxRBCMetz
DCLK1inactive (10001nM)-inactive (>10000nM)
DCLK2inactive (10001nM)inactive (100.27%)-
DCLK3inactive (10001nM)--
CAMK - MAPKAPK

Bioactivity
KinaseDRxRBCMetz
MAPKAPK2inactive (10001nM)inactive (98.83%)inactive (>7943.28nM)
MAPKAPK5inactive (10001nM)inactive (97.82%)inactive (>1584.89nM)
MNK1inactive (10001nM)inactive (98.47%)-
MNK2inactive (10001nM)inactive (100.75%)inactive (>10000nM)
MAPKAPK3-inactive (98.87%)inactive (>10000nM)
CAMK - MLCK

Bioactivity
KinaseDRxRBCMetz
caMLCKinactive (10001nM)--
smMLCKinactive (10001nM)inactive (97.55%)-
skMLCKinactive (10001nM)inactive (102.63%)-
SgK085inactive (10001nM)--
CAMK - PHK

Bioactivity
KinaseDRxRBCMetz
PHKg1inactive (10001nM)inactive (94.18%)-
PHKg2inactive (10001nM)inactive (91.76%)inactive (>5011.87nM)
CAMK - PIM

Bioactivity
KinaseDRxRBCMetz
PIM1inactive (10001nM)inactive (101.55%)inactive (>6309.57nM)
PIM2inactive (10001nM)inactive (95.84%)inactive (>1584.89nM)
PIM3inactive (10001nM)inactive (98.89%)inactive (>7943.28nM)
CAMK - PKD

Bioactivity
KinaseDRxRBCMetz
PKD1inactive (10001nM)inactive (100.55%)-
PKD2inactive (10001nM)inactive (86.01%)inactive (>10000nM)
PKD3inactive (10001nM)inactive (94.66%)inactive (>6309.57nM)
CAMK - STK33

Bioactivity
KinaseDRxRBCMetz
STK33inactive (10001nM)inactive (94.19%)-
CAMK - TSSK

Bioactivity
KinaseDRxRBCMetz
TSSK1inactive (10001nM)inactive (94.78%)inactive (>1584.89nM)
TSSK2-inactive (82.78%)inactive (>1584.89nM)

STE


Test Member No. in Family
Familyno. Member on 518kinaseDRxRBCMetz
883-
3127239
7732
2-2-
STE - STE11

Bioactivity
KinaseDRxRBCMetz
MAP3K5inactive (10001nM)inactive (101.32%)-
MAP3K6inactive (10001nM)--
MAP3K1inactive (10001nM)--
MAP3K7inactive (10001nM)--
MAP3K2inactive (10001nM)inactive (125.55%)-
MAP3K3inactive (10001nM)inactive (117.59%)-
MAP3K4inactive (10001nM)--
MAP3K8active (1900nM)--
STE - STE20

Bioactivity
KinaseDRxRBCMetz
HPK1inactive (10001nM)--
LOKinactive (10001nM)inactive (96.3%)-
GCKinactive (10001nM)inactive (107.1%)inactive (>5011.87nM)
KHS2inactive (10001nM)--
HGKinactive (10001nM)inactive (106.97%)inactive (>5011.87nM)
KHS1inactive (10001nM)inactive (100.75%)inactive (>6309.57nM)
MINKinactive (10001nM)inactive (104.05%)inactive (>7943.28nM)
MST1inactive (10001nM)inactive (104.57%)-
MST2inactive (10001nM)inactive (92.06%)inactive (6309.57nM)
MST3inactive (10001nM)inactive (98.65%)-
MST4inactive (10001nM)inactive (118.48%)-
MYO3Ainactive (10001nM)--
MYO3Binactive (10001nM)inactive (102.16%)-
OSR1inactive (10001nM)inactive (100.66%)-
PAK1inactive (10001nM)inactive (115.89%)inactive (>10000nM)
PAK2inactive (10001nM)inactive (100.6%)-
PAK3inactive (10001nM)inactive (106.6%)-
PAK4inactive (10001nM)inactive (95.76%)inactive (>5011.87nM)
PAK6inactive (10001nM)inactive (106.53%)-
PAK5inactive (10001nM)inactive (97.12%)-
SLKinactive (10001nM)inactive (94.16%)inactive (>10000nM)
STLK3inactive (10001nM)inactive (92.62%)-
TAO1inactive (10001nM)inactive (98.65%)inactive (>7943.28nM)
TAO2inactive (10001nM)inactive (85.41%)-
TAO3inactive (10001nM)inactive (99.89%)-
TNIKinactive (10001nM)--
YSK1inactive (10001nM)inactive (93.97%)-
STE - STE7

Bioactivity
KinaseDRxRBCMetz
MAP2K1inactive (10001nM)inactive (100.32%)inactive (>1995.26nM)
MAP2K2inactive (10001nM)inactive (100.37%)inactive (>3981.07nM)
MAP2K3inactive (10001nM)--
MAP2K4inactive (10001nM)--
MAP2K5inactive (10001nM)--
MAP2K6inactive (10001nM)inactive (95.34%)-
MAP2K7inactive (10001nM)--
STE - STE-Unique

Bioactivity
KinaseDRxRBCMetz
COT-inactive (98.16%)-
NIK-inactive (126.31%)-

CMGC


Test Member No. in Family
Familyno. Member on 518kinaseDRxRBCMetz
208-7
54--
4442
3221
10896
1414108
2222
32--
3331
CMGC - CDK

Bioactivity
KinaseDRxRBCMetz
PITSLREinactive (10001nM)--
CHEDinactive (10001nM)--
CDK11active (1500nM)--
PCTAIRE1inactive (10001nM)--
PCTAIRE2inactive (10001nM)--
PCTAIRE3inactive (10001nM)--
PFTAIRE2inactive (10001nM)--
PFTAIRE1inactive (10001nM)--
CDC2--inactive (>7943.28nM)
CDK2--inactive (>7943.28nM)
CDK5--inactive (>6309.57nM)
CDK8--inactive (>1995.26nM)
CDK7--inactive (>3981.07nM)
CDK9--inactive (>1584.89nM)
CMGC - CDKL

Bioactivity
KinaseDRxRBCMetz
CDKL1inactive (10001nM)--
CDKL2inactive (10001nM)--
CDKL3inactive (10001nM)--
CDKL5inactive (10001nM)--
CMGC - CLK

Bioactivity
KinaseDRxRBCMetz
CLK1inactive (10001nM)inactive (110.01%)-
CLK2inactive (10001nM)inactive (87.6%)inactive (>5011.87nM)
CLK3inactive (10001nM)inactive (104.92%)-
CLK4inactive (10001nM)inactive (108.35%)inactive (>3981.07nM)
CMGC - CK2

Bioactivity
KinaseDRxRBCMetz
CK2a1inactive (10001nM)inactive (113.84%)inactive (>6309.57nM)
CK2a2inactive (10001nM)inactive (105.72%)-
CMGC - DYRK

Bioactivity
KinaseDRxRBCMetz
DYRK1Ainactive (10001nM)inactive (101.83%)inactive (>3162.28nM)
DYRK1Binactive (10001nM)inactive (109.1%)inactive (>1258.93nM)
DYRK2inactive (10001nM)inactive (103.16%)-
HIPK1inactive (10001nM)inactive (99.18%)-
HIPK2inactive (10001nM)inactive (100.91%)inactive (>3162.28nM)
HIPK3inactive (10001nM)inactive (96.51%)-
HIPK4inactive (10001nM)inactive (95.92%)inactive (>7943.28nM)
PRP4inactive (10001nM)--
DYRK3-inactive (95.93%)inactive (>6309.57nM)
DYRK4-inactive (97.49%)inactive (>7943.28nM)
CMGC - MAPK

Bioactivity
KinaseDRxRBCMetz
Erk1inactive (10001nM)inactive (94.72%)-
Erk2inactive (10001nM)inactive (87.57%)inactive (>7943.28nM)
Erk3inactive (10001nM)--
Erk4inactive (10001nM)--
Erk5inactive (10001nM)--
Erk7inactive (10001nM)--
JNK1inactive (10001nM)inactive (98.2%)inactive (>3981.07nM)
JNK2inactive (10001nM)inactive (97.52%)inactive (>3981.07nM)
JNK3inactive (10001nM)inactive (115.88%)-
NLKinactive (10001nM)inactive (99.3%)-
p38ainactive (10001nM)inactive (98.21%)inactive (>3981.07nM)
p38binactive (10001nM)inactive (96.93%)-
p38dinactive (10001nM)inactive (88.86%)inactive (>7943.28nM)
p38ginactive (10001nM)inactive (96.81%)inactive (>6309.57nM)
CMGC - GSK

Bioactivity
KinaseDRxRBCMetz
GSK3Ainactive (10001nM)inactive (103.05%)inactive (>5011.87nM)
GSK3Binactive (10001nM)inactive (104.37%)inactive (>3981.07nM)
CMGC - RCK

Bioactivity
KinaseDRxRBCMetz
ICKinactive (10001nM)--
MAKinactive (10001nM)--
CMGC - SRPK

Bioactivity
KinaseDRxRBCMetz
SRPK1inactive (10001nM)inactive (98.48%)inactive (>7943.28nM)
SRPK2inactive (10001nM)inactive (96.53%)-
MSSK1inactive (10001nM)inactive (104.3%)-

CK1


Test Member No. in Family
Familyno. Member on 518kinaseDRxRBCMetz
7765
311-
CK1 - CK1

Bioactivity
KinaseDRxRBCMetz
CK1ainactive (10001nM)inactive (95.02%)inactive (>5011.87nM)
CK1a2inactive (10001nM)--
CK1dinactive (10001nM)inactive (92.23%)inactive (>7943.28nM)
CK1einactive (10001nM)inactive (99.13%)-
CK1g1inactive (10001nM)inactive (102.9%)inactive (>6309.57nM)
CK1g2inactive (10001nM)inactive (98.16%)inactive (>7943.28nM)
CK1g3inactive (10001nM)inactive (100.39%)inactive (>6309.57nM)
CK1 - VRK

Bioactivity
KinaseDRxRBCMetz
VRK2inactive (10001nM)--
VRK1-inactive (109.32%)-