Showing entry for Glyoxylic acid


　 　 　 　 　 　 　 　 　 　 　 　 　 　 　
General Compound Information
BXGC IdBXGC0000969
Compound NameGlyoxylic acid
Structure
FormulaC2H2O3
InchiKeyHHLFWLYXYJOTON-UHFFFAOYSA-N
SMILESOC(=O)C=O
InchiInChI=1S/C2H2O3/c3-1-2(4)5/h1H,(H,4,5)
IUPAC2-oxoacetic acid
Molecular Weight74.04
Pubchem Id760
Chembl IdCHEMBL1162545
Targets of Information Source
DrugBank DB04343
Uniport Id BXGT Id Protein Name Status Protein Class Gene Groups Target Type
Uniport Id BXGT Id Protein Name Status Protein Class Gene Groups Target Type
P37330 BXGT009978 Malate synthase G reviewed - glcB experimental -
P9WKK7 BXGT012372 Isocitrate lyase reviewed - icl experimental -
P9WK17 BXGT012353 Malate synthase G reviewed - glcB experimental -
P9WGY3 BXGT012281 Putative 4-hydroxy-4-methyl-2-oxoglutarate aldolase reviewed - rraA experimental -
PDB GLV
Uniport Id BXGT Id Protein Name Status Protein Class Gene Ki nM ic50 nM Kd nM Ka M-1
Uniport Id BXGT Id Protein Name Status Protein Class Gene Ki nM ic50 nM Kd nM Ka M-1
P37330 BXGT009978 Malate synthase G reviewed glcB - - - - -
P9WKK7 BXGT012372 Isocitrate lyase reviewed icl - - - - -
P9WK17 BXGT012353 Malate synthase G reviewed glcB - - - - -
P9WGY3 BXGT012281 Putative 4-hydroxy-4-methyl-2-oxoglutarate aldolase reviewed rraA - - - - -
P63486 BXGT011523 Ureidoglycolate lyase reviewed allA - - - - -
P43567 BXGT010399 Alanine--glyoxylate aminotransferase 1 reviewed AGX1 - - - - -
P45850 BXGT010486 Oxalate oxidase 1 reviewed - - - - -
P0CE47 BXGT007458 Elongation factor Tu 1 reviewed tufA - - - - -
Q3LSM4 BXGT014483 Serine--pyruvate aminotransferase unreviewed 5573438 - - - - -
Q9UJM8 BXGT021726 Hydroxyacid oxidase 1 reviewed HAO1 - - - - -
D4GTL2 BXGT002927 Malate synthase reviewed aceB - - - - -
O00255 BXGT003903 Menin reviewed MEN1 - - - - -
O75475 BXGT005130 PC4 and SFRS1-interacting protein reviewed PSIP1 Signaling - - - -
Q3J5L6 BXGT014445 L-malyl-CoA/beta-methylmalyl-CoA lyase reviewed mcl1 - - - - -
Q8CHT0 BXGT017939 Delta-1-pyrroline-5-carboxylate dehydrogenase, mitochondrial reviewed Aldh4a1 - - - - -
Q8VXY9 BXGT018959 Ureidoglycolate hydrolase reviewed UAH - - - - -
Q8U3Y2 BXGT018895 Glyoxylate reductase reviewed gyaR - - - - -
P0CT06 BXGT007485 Isocitrate lyase reviewed ICL1 - - - - -
A4GRC7 BXGT001216 Dehydrofolate reductase type I unreviewed dfrA1 - - - - -
P64312 BXGT011533 Protein/nucleic acid deglycase HchA reviewed hchA - - - - -
H8EVV4 BXGT003625 Isocitrate lyase 1 reviewed icl1 - - - - -
Q9I0K4 BXGT020689 Isocitrate lyase reviewed PA2634 - - - - -
P75913 BXGT025134 Glyoxylate/hydroxypyruvate reductase A reviewed ghrA - - - - -
Binding DB 19472
Uniport Id BXGT Id Protein Name Status Protein Class Gene Ki nM ic50 nM Kd nM EC50 nM
Uniport Id BXGT Id Protein Name Status Protein Class Gene Ki nM ic50 nM Kd nM EC50 nM
reviewed BXGT007063 4-hydroxy-tetrahydrodipicolinate synthase reviewed dapA 16000 - - -
CHEMBL CHEMBL1162545
Uniport Id BXGT Id Protein Name Status Protein Class Gene width="10%">Type Relation value Units
Uniport Id BXGT Id Protein Name Status Protein Class Gene Type Relation value Units
O15427 BXGT004167 Monocarboxylate transporter 4 reviewed Transporter SLC16A3 Activity - - -
P0A6L2 BXGT007063 4-hydroxy-tetrahydrodipicolinate synthase reviewed - dapA Ki '=' 16000 nM
Foods  containing  the  compound
Foods
BXGF Id Food Name Scientific Name Food Group
BXGF Id Food Name Scientific Name Food Group
BXGF00016 Peanut Arachis hypogaea Nuts
BXGF00047 Chickpea Cicer arietinum Pulses
BXGF00081 Fig Ficus carica Fruits
BXGF00105 Apple Malus pumila Fruits
BXGF00157 Gooseberry Ribes uva-crispa Fruits
BXGF00175 Potato Solanum tuberosum Vegetables
BXGF00180 Tamarind Tamarindus indica Fruits
BXGF00246 Red beetroot Beta vulgaris var. rubra Vegetables
BXGF00400 French plantain Musa X paradisiaca Fruits
The  compound-realted  diseases
Diseases
BXGD Id Disease Name CUI Disease Id Disease Class Name Number of targets?Number of targets related to compound connecting disease, higher numbers indicate the compound is more associated with the disease