Showing entry for Myrosin


　 　 　 　 　 　 　 　 　 　 　 　 　 　 　
General Compound Information
BXGC IdBXGC0002883
Compound NameMyrosin
Structure
FormulaC7H6O4
InchiKeyZRWPUFFVAOMMNM-UHFFFAOYSA-N
SMILESOC1OCC=C2OC(=O)C=C12
InchiInChI=1S/C7H6O4/c8-6-3-4-5(11-6)1-2-10-7(4)9/h1,3,7,9H,2H2
IUPAC4-hydroxy-2H,4H,6H-furo[3,2-c]pyran-2-one
Molecular Weight154.12
Pubchem Id4696
Chembl IdCHEMBL294018
Targets of Information Source
DrugBank n.a
Uniport Id BXGT Id Protein Name Status Protein Class Gene Groups Target Type
Uniport Id BXGT Id Protein Name Status Protein Class Gene Groups Target Type
PDB n.a
Uniport Id BXGT Id Protein Name Status Protein Class Gene Ki nM ic50 nM Kd nM Ka M-1
Uniport Id BXGT Id Protein Name Status Protein Class Gene Ki nM ic50 nM Kd nM Ka M-1
Binding DB n.a
Uniport Id BXGT Id Protein Name Status Protein Class Gene Ki nM ic50 nM Kd nM EC50 nM
Uniport Id BXGT Id Protein Name Status Protein Class Gene Ki nM ic50 nM Kd nM EC50 nM
CHEMBL CHEMBL294018
Uniport Id BXGT Id Protein Name Status Protein Class Gene width="10%">Type Relation value Units
Uniport Id BXGT Id Protein Name Status Protein Class Gene Type Relation value Units
P19793 BXGT008515 Retinoic acid receptor RXR-alpha reviewed Nuclear receptor RXRA Potency - 19952 nM
O94782 BXGT005332 Ubiquitin carboxyl-terminal hydrolase 1 reviewed Enzyme USP1 Potency - 50118 nM
Q9NUW8 BXGT021219 Tyrosyl-DNA phosphodiesterase 1 reviewed Enzyme TDP1 Potency - 145 nM
Q96RI1 BXGT019727 Bile acid receptor reviewed Nuclear receptor NR1H4 Potency - 19952 nM
P28482 BXGT009263 Mitogen-activated protein kinase 1 reviewed Kinase MAPK1 Potency '=' 31622 nM
P23528 BXGT008879 Cofilin-1 reviewed - CFL1 Activity - - -
P37231 BXGT009972 Peroxisome proliferator-activated receptor gamma reviewed Nuclear receptor PPARG Potency - 19952 nM
Q16637 BXGT013646 Survival motor neuron protein reviewed Epigenetic regulator SMN1 Potency '=' 17782 nM
A3EZI9 BXGT001153 Genome polyprotein unreviewed - NS3 IC50 '=' 3800 nM
A3EZI9 BXGT001153 Genome polyprotein unreviewed - NS3 IC50 '=' 3 ug.mL-1
P10636 BXGT007596 Microtubule-associated protein tau reviewed - MAPT Potency '=' 2238 nM
P11473 BXGT007709 Vitamin D3 receptor reviewed Nuclear receptor VDR Potency - 12589 nM
P10636 BXGT007596 Microtubule-associated protein tau reviewed - MAPT Potency '=' 1995 nM
P00352 BXGT005510 Retinal dehydrogenase 1 reviewed Enzyme ALDH1A1 Potency '=' 35481 nM
P29597 BXGT009367 Non-receptor tyrosine-protein kinase TYK2 reviewed Kinase TYK2 Inhibition '=' 25 %
O60674 BXGT004892 Tyrosine-protein kinase JAK2 reviewed Kinase JAK2 Inhibition '=' 25 %
P23458 BXGT008868 Tyrosine-protein kinase JAK1 reviewed Kinase JAK1 Inhibition '=' 25 %
P52333 BXGT010928 Tyrosine-protein kinase JAK3 reviewed Kinase JAK3 Inhibition '=' 25 %
P11473 BXGT007709 Vitamin D3 receptor reviewed Nuclear receptor VDR Potency - 25118 nM
P06493 BXGT006445 Cyclin-dependent kinase 1 reviewed Kinase CDK1 Activity - - -
Q9NPD5 BXGT021151 Solute carrier organic anion transporter family member 1B3 reviewed Transporter SLCO1B3 Inhibition '=' 79 %
P04637 BXGT006243 Cellular tumor antigen p53 reviewed Transcription factor TP53 Potency '=' 7943 nM
Q16236 BXGT013624 Nuclear factor erythroid 2-related factor 2 reviewed Enzyme NFE2L2 Potency - 4327 nM
Q03181 BXGT012701 Peroxisome proliferator-activated receptor delta reviewed Nuclear receptor PPARD Potency - 6309 nM
P04150 BXGT006154 Glucocorticoid receptor reviewed Nuclear receptor NR3C1 Potency - 6309 nM
P03372 BXGT006059 Estrogen receptor reviewed Nuclear receptor ESR1 Potency - 25118 nM
P11021 BXGT007644 Endoplasmic reticulum chaperone BiP reviewed - HSPA5 Potency - 5011 nM
P53778 BXGT011013 Mitogen-activated protein kinase 12 reviewed Kinase MAPK12 Inhibition '=' 25 %
Q16539 BXGT013634 Mitogen-activated protein kinase 14 reviewed Kinase MAPK14 Inhibition '=' 25 %
Q15759 BXGT013595 Mitogen-activated protein kinase 11 reviewed Kinase MAPK11 Inhibition '=' 25 %
O15264 BXGT004144 Mitogen-activated protein kinase 13 reviewed Kinase MAPK13 Inhibition '=' 25 %
Q9Y6L6 BXGT022334 Solute carrier organic anion transporter family member 1B1 reviewed Transporter SLCO1B1 Inhibition '=' 81 %
P04637 BXGT006243 Cellular tumor antigen p53 reviewed Transcription factor TP53 Potency '=' 12589 nM
O42275 BXGT004559 Acetylcholinesterase reviewed - ache Inhibition '=' 5 %
P29597 BXGT009367 Non-receptor tyrosine-protein kinase TYK2 reviewed Kinase TYK2 Inhibition '>' 65 %
O60674 BXGT004892 Tyrosine-protein kinase JAK2 reviewed Kinase JAK2 Inhibition '>' 65 %
P23458 BXGT008868 Tyrosine-protein kinase JAK1 reviewed Kinase JAK1 Inhibition '>' 65 %
P52333 BXGT010928 Tyrosine-protein kinase JAK3 reviewed Kinase JAK3 Inhibition '>' 65 %
P04637 BXGT006243 Cellular tumor antigen p53 reviewed Transcription factor TP53 Activity - - -
P05412 BXGT006354 Transcription factor AP-1 reviewed Transcription factor JUN Activity - - -
Q9UBT6 BXGT021664 DNA polymerase kappa reviewed - POLK Potency - 35481 nM
P35869 BXGT009877 Aryl hydrocarbon receptor reviewed Transcription factor AHR Potency - 12589 nM
P51450 BXGT010847 Nuclear receptor ROR-gamma reviewed - Rorc Potency '=' 891 nM
P51450 BXGT010847 Nuclear receptor ROR-gamma reviewed - Rorc Potency '=' 1122 nM
P81908 BXGT011959 Cholinesterase reviewed - BCHE Inhibition '=' -1 %
Q9NUW8 BXGT021219 Tyrosyl-DNA phosphodiesterase 1 reviewed Enzyme TDP1 Potency - 103 nM
P28482 BXGT009263 Mitogen-activated protein kinase 1 reviewed Kinase MAPK1 Potency '=' 39810 nM
P04150 BXGT006154 Glucocorticoid receptor reviewed Nuclear receptor NR3C1 Potency - 31622 nM
P10828 BXGT007624 Thyroid hormone receptor beta reviewed Nuclear receptor THRB Potency - 8912 nM
P19793 BXGT008515 Retinoic acid receptor RXR-alpha reviewed Nuclear receptor RXRA Potency - 12589 nM
P27695 BXGT009199 DNA-(apurinic or apyrimidinic site) lyase reviewed - APEX1 Potency - 31622 nM
Foods  containing  the  compound
Foods
BXGF Id Food Name Scientific Name Food Group
BXGF Id Food Name Scientific Name Food Group
BXGF00018 Horseradish Armoracia rusticana Herbs and Spices
BXGF00041 Papaya Carica papaya Fruits
BXGF00099 Garden cress Lepidium sativum Vegetables
BXGF00346 Horseradish tree Moringa oleifera Vegetables
BXGF00380 White mustard Sinapis alba Herbs and Spices
BXGF00808 Pomes Fruits
The  compound-realted  diseases
Diseases
BXGD Id Disease Name CUI Disease Id Disease Class Name Number of targets?Number of targets related to compound connecting disease, higher numbers indicate the compound is more associated with the disease