Showing entry for Cyclin-dependent kinase 1


　 　 　 　 　 　 　 　 　 　 　 　
General Target Information
BXGT IdBXGT006445
Protein NameCyclin-dependent kinase 1
Uniport IdP06493
GeneCDK1
Gene Id983
DomainPkinase
Pfam PF00069  
OrganismHomo sapiens (Human)
Target protein  affiliated  biological  pathways
KEGG
Class Subclass KEGG Id Pathway Name
4. Cellular Processes 4.2 Cell growth and death hsa04110 Cell cycle
4. Cellular Processes 4.2 Cell growth and death hsa04114 Oocyte meiosis
4. Cellular Processes 4.2 Cell growth and death hsa04115 p53 signaling pathway
4. Cellular Processes 4.2 Cell growth and death hsa04218 Cellular senescence
4. Cellular Processes 4.3 Cellular community - eukaryotes hsa04540 Gap junction
5. Organismal Systems 5.2 Endocrine system hsa04914 Progesterone-mediated oocyte maturation
6. Human Diseases 6.9 Infectious diseases: Viral hsa05170 Human immunodeficiency virus 1 infection
6. Human Diseases 6.1 Cancers: Overview hsa05203 Viral carcinogenesis
Gene Ontology
GO Type GO Id Gene Ontology
Biological Process GO:0000187 activation of MAPK activity
Biological Process GO:0031145 anaphase-promoting complex-dependent catabolic process
Biological Process GO:0031100 animal organ regeneration
Biological Process GO:0006915 apoptotic process
Biological Process GO:0007569 cell aging
Biological Process GO:0051301 cell division
Biological Process GO:0016477 cell migration
Biological Process GO:0008283 cell population proliferation
Biological Process GO:0070301 cellular response to hydrogen peroxide
Biological Process GO:0007098 centrosome cycle
Biological Process GO:0030261 chromosome condensation
Biological Process GO:0097711 ciliary basal body-plasma membrane docking
Biological Process GO:0006977 DNA damage response, signal transduction by p53 class mediator resulting in cell cycle arrest
Biological Process GO:0006281 DNA repair
Biological Process GO:0006260 DNA replication
Biological Process GO:0030855 epithelial cell differentiation
Biological Process GO:0000086 G2/M transition of mitotic cell cycle
Biological Process GO:0090166 Golgi disassembly
Biological Process GO:0000226 microtubule cytoskeleton organization
Biological Process GO:0007095 mitotic G2 DNA damage checkpoint
Biological Process GO:0007077 mitotic nuclear envelope disassembly
Biological Process GO:0043066 negative regulation of apoptotic process
Biological Process GO:0018105 peptidyl-serine phosphorylation
Biological Process GO:0018107 peptidyl-threonine phosphorylation
Biological Process GO:0060045 positive regulation of cardiac muscle cell proliferation
Biological Process GO:0045740 positive regulation of DNA replication
Biological Process GO:0010971 positive regulation of G2/M transition of mitotic cell cycle
Biological Process GO:0010628 positive regulation of gene expression
Biological Process GO:1905448 positive regulation of mitochondrial ATP synthesis coupled electron transport
Biological Process GO:0042307 positive regulation of protein import into nucleus
Biological Process GO:1900182 positive regulation of protein localization to nucleus
Biological Process GO:0007344 pronuclear fusion
Biological Process GO:0065003 protein-containing complex assembly
Biological Process GO:0016579 protein deubiquitination
Biological Process GO:0034501 protein localization to kinetochore
Biological Process GO:0006468 protein phosphorylation
Biological Process GO:0042752 regulation of circadian rhythm
Biological Process GO:0045995 regulation of embryonic development
Biological Process GO:0010389 regulation of G2/M transition of mitotic cell cycle
Biological Process GO:1901990 regulation of mitotic cell cycle phase transition
Biological Process GO:0014038 regulation of Schwann cell differentiation
Biological Process GO:0014823 response to activity
Biological Process GO:0014075 response to amine
Biological Process GO:0048678 response to axon injury
Biological Process GO:0046686 response to cadmium ion
Biological Process GO:0046688 response to copper ion
Biological Process GO:0042493 response to drug
Biological Process GO:0045471 response to ethanol
Biological Process GO:0014070 response to organic cyclic compound
Biological Process GO:0009636 response to toxic substance
Biological Process GO:0048511 rhythmic process
Biological Process GO:0006367 transcription initiation from RNA polymerase II promoter
Biological Process GO:0055015 ventricular cardiac muscle cell development
molecular function GO:0005524 ATP binding
molecular function GO:0003682 chromatin binding
molecular function GO:0030332 cyclin binding
molecular function GO:0097472 cyclin-dependent protein kinase activity
molecular function GO:0004693 cyclin-dependent protein serine/threonine kinase activity
molecular function GO:0035173 histone kinase activity
molecular function GO:0030544 Hsp70 protein binding
molecular function GO:0004672 protein kinase activity
molecular function GO:0004674 protein serine/threonine kinase activity
molecular function GO:0008353 RNA polymerase II CTD heptapeptide repeat kinase activity
molecular function GO:0001618 virus receptor activity
cellular component GO:0005813 centrosome
cellular component GO:0097125 cyclin B1-CDK1 complex
cellular component GO:0000307 cyclin-dependent protein kinase holoenzyme complex
cellular component GO:0005737 cytoplasm
cellular component GO:0005829 cytosol
cellular component GO:0005789 endoplasmic reticulum membrane
cellular component GO:0070062 extracellular exosome
cellular component GO:0016020 membrane
cellular component GO:0030496 midbody
cellular component GO:0005759 mitochondrial matrix
cellular component GO:0005739 mitochondrion
cellular component GO:0072686 mitotic spindle
cellular component GO:0000784 nuclear chromosome, telomeric region
cellular component GO:0005654 nucleoplasm
cellular component GO:0005634 nucleus
cellular component GO:0005876 spindle microtubule
Reactome
Pathway Id Pathway Name
R-HSA-110056 MAPK3 (ERK1) activation
R-HSA-112409 RAF-independent MAPK1/3 activation
R-HSA-113507 E2F-enabled inhibition of pre-replication complex formation
R-HSA-113510 E2F mediated regulation of DNA replication
R-HSA-1362300 Transcription of E2F targets under negative control by p107 (RBL1) and p130 (RBL2) in complex with HDAC1
R-HSA-1538133 G0 and Early G1
R-HSA-162582 Signal Transduction
R-HSA-162658 Golgi Cisternae Pericentriolar Stack Reorganization
R-HSA-1640170 Cell Cycle
R-HSA-1640170 Cell Cycle
R-HSA-170145 Phosphorylation of proteins involved in the G2/M transition by Cyclin A:Cdc2 complexes
R-HSA-174048 APC/C:Cdc20 mediated degradation of Cyclin B
R-HSA-174143 APC/C-mediated degradation of cell cycle proteins
R-HSA-174184 Cdc20:Phospho-APC/C mediated degradation of Cyclin A
R-HSA-176408 Regulation of APC/C activators between G1/S and early anaphase
R-HSA-176409 APC/C:Cdc20 mediated degradation of mitotic proteins
R-HSA-176412 Phosphorylation of the APC/C
R-HSA-176417 Phosphorylation of Emi1
R-HSA-176814 Activation of APC/C and APC/C:Cdc20 mediated degradation of mitotic proteins
R-HSA-179419 APC:Cdc20 mediated degradation of cell cycle proteins prior to satisfation of the cell cycle checkpoint
R-HSA-1852241 Organelle biogenesis and maintenance
R-HSA-212436 Generic Transcription Pathway
R-HSA-2299718 Condensation of Prophase Chromosomes
R-HSA-2465910 MASTL Facilitates Mitotic Progression
R-HSA-2500257 Resolution of Sister Chromatid Cohesion
R-HSA-2514853 Condensation of Prometaphase Chromosomes
R-HSA-2555396 Mitotic Metaphase and Anaphase
R-HSA-2565942 Regulation of PLK1 Activity at G2/M Transition
R-HSA-2980766 Nuclear Envelope Breakdown
R-HSA-2980767 Activation of NIMA Kinases NEK9, NEK6, NEK7
R-HSA-2995383 Initiation of Nuclear Envelope (NE) Reformation
R-HSA-2995410 Nuclear Envelope (NE) Reassembly
R-HSA-3301854 Nuclear Pore Complex (NPC) Disassembly
R-HSA-3700989 Transcriptional Regulation by TP53
R-HSA-380259 Loss of Nlp from mitotic centrosomes
R-HSA-380270 Recruitment of mitotic centrosome proteins and complexes
R-HSA-380284 Loss of proteins required for interphase microtubule organization from the centrosome
R-HSA-380287 Centrosome maturation
R-HSA-380320 Recruitment of NuMA to mitotic centrosomes
R-HSA-392499 Metabolism of proteins
R-HSA-4419969 Depolymerisation of the Nuclear Lamina
R-HSA-453274 Mitotic G2-G2/M phases
R-HSA-453274 Mitotic G2-G2/M phases
R-HSA-453276 Regulation of mitotic cell cycle
R-HSA-453279 Mitotic G1 phase and G1/S transition
R-HSA-5617833 Cilium Assembly
R-HSA-5620912 Anchoring of the basal body to the plasma membrane
R-HSA-5633007 Regulation of TP53 Activity
R-HSA-5683057 MAPK family signaling cascades
R-HSA-5684996 MAPK1/MAPK3 signaling
R-HSA-5687128 MAPK6/MAPK4 signaling
R-HSA-5688426 Deubiquitination
R-HSA-5689896 Ovarian tumor domain proteases
R-HSA-597592 Post-translational protein modification
R-HSA-6791312 TP53 Regulates Transcription of Cell Cycle Genes
R-HSA-6804114 TP53 Regulates Transcription of Genes Involved in G2 Cell Cycle Arrest
R-HSA-6804757 Regulation of TP53 Degradation
R-HSA-6806003 Regulation of TP53 Expression and Degradation
R-HSA-68875 Mitotic Prophase
R-HSA-68875 Mitotic Prophase
R-HSA-68877 Mitotic Prometaphase
R-HSA-68877 Mitotic Prometaphase
R-HSA-68882 Mitotic Anaphase
R-HSA-68886 M Phase
R-HSA-68886 M Phase
R-HSA-69205 G1/S-Specific Transcription
R-HSA-69206 G1/S Transition
R-HSA-69273 Cyclin A/B1/B2 associated events during G2/M transition
R-HSA-69273 Cyclin A/B1/B2 associated events during G2/M transition
R-HSA-69275 G2/M Transition
R-HSA-69275 G2/M Transition
R-HSA-69278 Cell Cycle, Mitotic
R-HSA-69278 Cell Cycle, Mitotic
R-HSA-69473 G2/M DNA damage checkpoint
R-HSA-69478 G2/M DNA replication checkpoint
R-HSA-69481 G2/M Checkpoints
R-HSA-69620 Cell Cycle Checkpoints
R-HSA-73857 RNA Polymerase II Transcription
R-HSA-74160 Gene expression (Transcription)
R-HSA-75035 Chk1/Chk2(Cds1) mediated inactivation of Cyclin B:Cdk1 complex
R-HSA-8852276 The role of GTSE1 in G2/M progression after G2 checkpoint
R-HSA-8854518 AURKA Activation by TPX2
R-HSA-8878166 Transcriptional regulation by RUNX2
Target protein-related  diseases
Disease
CUI Id BXGD Id Disease Name Disease Class
C0001418 BXGD000050 Adenocarcinoma Neoplasms
C0001430 BXGD000054 Adenoma Neoplasms
C0002395 BXGD000111 Alzheimer's Disease Nervous System Diseases; Mental Disorders
C0002893 BXGD000150 Refractory anemias Hemic and Lymphatic Diseases
C0003504 BXGD000202 Aortic Valve Insufficiency Cardiovascular Diseases
C0003873 BXGD000236 Rheumatoid Arthritis Skin and Connective Tissue Diseases; Musculoskeletal Diseases; Immune System Diseases
C0004134 BXGD000256 Ataxia Pathological Conditions, Signs and Symptoms; Nervous System Diseases
C0004135 BXGD000257 Ataxia Telangiectasia Congenital, Hereditary, and Neonatal Diseases and Abnormalities; Nutritional and Metabolic Diseases; Immune System Diseases; Nervous System Diseases; Cardiovascular Diseases
C0004364 BXGD000270 Autoimmune Diseases Immune System Diseases
C0005684 BXGD000319 Malignant neoplasm of urinary bladder Neoplasms; Female Urogenital Diseases and Pregnancy Complications; Male Urogenital Diseases
C0006142 BXGD000374 Malignant neoplasm of breast Neoplasms; Skin and Connective Tissue Diseases
C0006826 BXGD000408 Malignant Neoplasms Neoplasms
C0007097 BXGD000424 Carcinoma Neoplasms
C0007102 BXGD000425 Malignant tumor of colon Digestive System Diseases; Neoplasms
C0007103 BXGD000426 Malignant neoplasm of endometrium Neoplasms; Female Urogenital Diseases and Pregnancy Complications
C0007131 BXGD000441 Non-Small Cell Lung Carcinoma Neoplasms; Respiratory Tract Diseases
C0007134 BXGD000443 Renal Cell Carcinoma Neoplasms; Female Urogenital Diseases and Pregnancy Complications; Male Urogenital Diseases
C0007137 BXGD000445 Squamous cell carcinoma Neoplasms
C0007758 BXGD000475 Cerebellar Ataxia Pathological Conditions, Signs and Symptoms; Nervous System Diseases
C0007847 BXGD000492 Malignant tumor of cervix Neoplasms; Female Urogenital Diseases and Pregnancy Complications
C0009402 BXGD000605 Colorectal Carcinoma Digestive System Diseases; Neoplasms
C0009404 BXGD000606 Colorectal Neoplasms Digestive System Diseases; Neoplasms
C0013080 BXGD000797 Down Syndrome Congenital, Hereditary, and Neonatal Diseases and Abnormalities; Nervous System Diseases
C0014175 BXGD000904 Endometriosis Female Urogenital Diseases and Pregnancy Complications
C0014378 BXGD000912 Enterovirus Infections Infections
C0014544 BXGD000926 Epilepsy Nervous System Diseases
C0015625 BXGD001006 Fanconi Anemia Congenital, Hereditary, and Neonatal Diseases and Abnormalities; Nutritional and Metabolic Diseases; Hemic and Lymphatic Diseases
C0017636 BXGD001131 Glioblastoma Neoplasms
C0017638 BXGD001132 Glioma Neoplasms
C0019158 BXGD001293 Hepatitis Digestive System Diseases
C0019163 BXGD001295 Hepatitis B Digestive System Diseases; Infections
C0019187 BXGD001296 Hepatitis, Alcoholic Digestive System Diseases; Chemically-Induced Disorders
C0019196 BXGD001301 Hepatitis C Digestive System Diseases; Infections
C0019348 BXGD001325 Herpes Simplex Infections Infections; Skin and Connective Tissue Diseases
C0019693 BXGD001346 HIV Infections Infections; Immune System Diseases
C0021400 BXGD001504 Influenza Infections; Respiratory Tract Diseases
C0021670 BXGD001509 insulinoma Digestive System Diseases; Neoplasms; Endocrine System Diseases
C0023418 BXGD001642 leukemia Neoplasms
C0023434 BXGD001643 Chronic Lymphocytic Leukemia Neoplasms; Immune System Diseases; Hemic and Lymphatic Diseases
C0023452 BXGD001651 Childhood Acute Lymphoblastic Leukemia Neoplasms; Immune System Diseases; Hemic and Lymphatic Diseases
C0023467 BXGD001658 Leukemia, Myelocytic, Acute Neoplasms
C0023487 BXGD001669 Acute Promyelocytic Leukemia Neoplasms
C0023890 BXGD001713 Liver Cirrhosis Pathological Conditions, Signs and Symptoms; Digestive System Diseases
C0023893 BXGD001716 Liver Cirrhosis, Experimental Pathological Conditions, Signs and Symptoms; Digestive System Diseases
C0023903 BXGD001720 Liver neoplasms Digestive System Diseases; Neoplasms
C0024131 BXGD001736 Lupus Vulgaris Infections; Skin and Connective Tissue Diseases
C0024138 BXGD001738 Lupus Erythematosus, Discoid Skin and Connective Tissue Diseases
C0024141 BXGD001740 Lupus Erythematosus, Systemic Skin and Connective Tissue Diseases; Immune System Diseases
C0024299 BXGD001758 Lymphoma Neoplasms; Immune System Diseases; Hemic and Lymphatic Diseases
C0024537 BXGD001786 Malaria, Vivax Infections
C0024623 BXGD001791 Malignant neoplasm of stomach Digestive System Diseases; Neoplasms
C0025064 BXGD001825 Mediastinitis Respiratory Tract Diseases
C0025149 BXGD001826 Medulloblastoma Neoplasms
C0025202 BXGD001832 melanoma Neoplasms
C0025286 BXGD001850 Meningioma Neoplasms; Nervous System Diseases
C0025322 BXGD001863 Premature Menopause Female Urogenital Diseases and Pregnancy Complications
C0026764 BXGD001928 Multiple Myeloma Neoplasms; Immune System Diseases; Hemic and Lymphatic Diseases; Cardiovascular Diseases
C0027051 BXGD001963 Myocardial Infarction Pathological Conditions, Signs and Symptoms; Cardiovascular Diseases
C0027627 BXGD002006 Neoplasm Metastasis Pathological Conditions, Signs and Symptoms; Neoplasms
C0027651 BXGD002009 Neoplasms Neoplasms
C0027654 BXGD002010 Embryonal Neoplasm Neoplasms
C0027819 BXGD002043 Neuroblastoma Neoplasms
C0028754 BXGD002082 Obesity Pathological Conditions, Signs and Symptoms; Nutritional and Metabolic Diseases
C0029408 BXGD002137 Degenerative polyarthritis Musculoskeletal Diseases
C0029456 BXGD002157 Osteoporosis Nutritional and Metabolic Diseases; Musculoskeletal Diseases
C0029463 BXGD002160 Osteosarcoma Neoplasms
C0029925 BXGD002181 Ovarian Carcinoma Neoplasms; Female Urogenital Diseases and Pregnancy Complications; Endocrine System Diseases
C0030567 BXGD002240 Parkinson Disease Nervous System Diseases
C0032580 BXGD002362 Adenomatous Polyposis Coli Congenital, Hereditary, and Neonatal Diseases and Abnormalities; Digestive System Diseases; Neoplasms
C0033578 BXGD002408 Prostatic Neoplasms Neoplasms; Male Urogenital Diseases
C0035335 BXGD002540 Retinoblastoma Neoplasms; Eye Diseases
C0036220 BXGD002587 Kaposi Sarcoma Neoplasms; Infections
C0039538 BXGD002819 Teratoma Neoplasms
C0040136 BXGD002845 Thyroid Neoplasm Neoplasms; Endocrine System Diseases
C0042769 BXGD002999 Virus Diseases Infections
C0079588 BXGD003084 Ichthyosis, X-Linked Congenital, Hereditary, and Neonatal Diseases and Abnormalities; Nutritional and Metabolic Diseases; Skin and Connective Tissue Diseases
C0079731 BXGD003087 B-Cell Lymphomas Neoplasms; Immune System Diseases; Hemic and Lymphatic Diseases
C0079744 BXGD003090 Diffuse Large B-Cell Lymphoma Neoplasms; Immune System Diseases; Hemic and Lymphatic Diseases
C0085207 BXGD003140 Gestational Diabetes Nutritional and Metabolic Diseases; Female Urogenital Diseases and Pregnancy Complications; Endocrine System Diseases
C0085215 BXGD003141 Ovarian Failure, Premature Female Urogenital Diseases and Pregnancy Complications; Endocrine System Diseases
C0085270 BXGD003147 Orbital Pseudotumor Eye Diseases
C0085413 BXGD003171 Polycystic Kidney, Autosomal Dominant Congenital, Hereditary, and Neonatal Diseases and Abnormalities; Female Urogenital Diseases and Pregnancy Complications; Male Urogenital Diseases
C0151449 BXGD003419 Primary Sjögren's syndrome Eye Diseases; Skin and Connective Tissue Diseases; Musculoskeletal Diseases; Immune System Diseases; Stomatognathic Diseases
C0152013 BXGD003516 Adenocarcinoma of lung (disorder) Neoplasms
C0153381 BXGD003626 Malignant neoplasm of mouth Neoplasms; Stomatognathic Diseases
C0175754 BXGD004015 Agenesis of corpus callosum Pathological Conditions, Signs and Symptoms; Congenital, Hereditary, and Neonatal Diseases and Abnormalities; Nervous System Diseases
C0178874 BXGD004037 Tumor Progression Pathological Conditions, Signs and Symptoms
C0205768 BXGD004119 Subependymal Giant Cell Astrocytoma Neoplasms
C0206624 BXGD004190 Hepatoblastoma Neoplasms
C0206698 BXGD004248 Cholangiocarcinoma Neoplasms
C0206716 BXGD004262 Ganglioglioma Neoplasms
C0206721 BXGD004267 Inverted Papilloma Neoplasms
C0220620 BXGD004299 Gastrointestinal Carcinoid Tumor Digestive System Diseases; Neoplasms; Endocrine System Diseases
C0220641 BXGD004305 Lip and Oral Cavity Carcinoma Neoplasms; Stomatognathic Diseases
C0220668 BXGD004317 Congenital contractural arachnodactyly Congenital, Hereditary, and Neonatal Diseases and Abnormalities; Musculoskeletal Diseases
C0221106 BXGD004390 Alkalemia
C0235974 BXGD004796 Pancreatic carcinoma Digestive System Diseases; Neoplasms; Endocrine System Diseases
C0236642 BXGD004815 Pick Disease of the Brain Nervous System Diseases; Mental Disorders
C0236734 BXGD004823 Caffeine related disorders
C0238198 BXGD004893 Gastrointestinal Stromal Tumors Digestive System Diseases; Neoplasms
C0238461 BXGD004936 Anaplastic thyroid carcinoma Neoplasms
C0242379 BXGD005157 Malignant neoplasm of lung Neoplasms; Respiratory Tract Diseases
C0262985 BXGD005277 Psoriasiform eczema Skin and Connective Tissue Diseases
C0271333 BXGD006185 Orbital lymphoma Neoplasms; Eye Diseases; Musculoskeletal Diseases; Immune System Diseases; Hemic and Lymphatic Diseases
C0278488 BXGD006515 Carcinoma breast stage IV
C0278510 BXGD006526 Childhood Medulloblastoma Neoplasms
C0278876 BXGD006607 Adult Medulloblastoma Neoplasms
C0278877 BXGD006608 Adult Meningioma Neoplasms; Nervous System Diseases
C0278878 BXGD006609 Adult Glioblastoma Neoplasms
C0279628 BXGD006659 Adenocarcinoma Of Esophagus Digestive System Diseases; Neoplasms
C0279702 BXGD006685 Conventional (Clear Cell) Renal Cell Carcinoma Neoplasms; Female Urogenital Diseases and Pregnancy Complications; Male Urogenital Diseases
C0280232 BXGD006724 stage, cervical cancer Neoplasms; Female Urogenital Diseases and Pregnancy Complications
C0280324 BXGD006740 Laryngeal Squamous Cell Carcinoma Neoplasms; Respiratory Tract Diseases; Otorhinolaryngologic Diseases
C0280474 BXGD006748 Childhood Glioblastoma Neoplasms
C0280856 BXGD006767 Squamous cell carcinoma of vulva Neoplasms; Female Urogenital Diseases and Pregnancy Complications
C0282160 BXGD006797 Aplasia Cutis Congenita Congenital, Hereditary, and Neonatal Diseases and Abnormalities; Skin and Connective Tissue Diseases
C0302592 BXGD006851 Cervix carcinoma Neoplasms; Female Urogenital Diseases and Pregnancy Complications
C0333463 BXGD006954 Senile Plaques Pathological Conditions, Signs and Symptoms
C0338451 BXGD007176 Frontotemporal dementia Nutritional and Metabolic Diseases; Nervous System Diseases; Mental Disorders
C0343641 BXGD007636 Human papilloma virus infection Infections
C0345904 BXGD007745 Malignant neoplasm of liver Digestive System Diseases; Neoplasms
C0346647 BXGD007832 Malignant neoplasm of pancreas Digestive System Diseases; Neoplasms; Endocrine System Diseases
C0375071 BXGD007972 Malignant neoplasm of vulva Neoplasms; Female Urogenital Diseases and Pregnancy Complications
C0376358 BXGD007992 Malignant neoplasm of prostate Neoplasms; Male Urogenital Diseases
C0406557 BXGD008349 Poikiloderma of Kindler Pathological Conditions, Signs and Symptoms; Congenital, Hereditary, and Neonatal Diseases and Abnormalities; Skin and Connective Tissue Diseases; Stomatognathic Diseases
C0409974 BXGD008401 Lupus Erythematosus Pathological Conditions, Signs and Symptoms; Skin and Connective Tissue Diseases; Immune System Diseases
C0424295 BXGD008524 Hyperactive behavior Pathological Conditions, Signs and Symptoms; Nervous System Diseases
C0476089 BXGD008977 Endometrial Carcinoma Neoplasms; Female Urogenital Diseases and Pregnancy Complications
C0494463 BXGD009029 Alzheimer Disease, Late Onset Nervous System Diseases; Mental Disorders
C0521158 BXGD009130 Recurrent tumor
C0524851 BXGD009246 Neurodegenerative Disorders Nervous System Diseases
C0555198 BXGD009432 Malignant Glioma Neoplasms
C0585442 BXGD009593 Osteosarcoma of bone Neoplasms
C0596263 BXGD009639 Carcinogenesis Pathological Conditions, Signs and Symptoms; Neoplasms
C0598766 BXGD009669 Leukemogenesis Pathological Conditions, Signs and Symptoms; Neoplasms
C0598935 BXGD009674 Tumor Initiation Pathological Conditions, Signs and Symptoms; Neoplasms
C0600139 BXGD009695 Prostate carcinoma Neoplasms; Male Urogenital Diseases
C0677055 BXGD009715 CARCINOMA OF VULVA Neoplasms; Female Urogenital Diseases and Pregnancy Complications
C0677886 BXGD009734 Epithelial ovarian cancer Neoplasms; Female Urogenital Diseases and Pregnancy Complications; Endocrine System Diseases
C0677948 BXGD009739 Stage II Colorectal Cancer Digestive System Diseases; Neoplasms
C0678222 BXGD009749 Breast Carcinoma Neoplasms; Skin and Connective Tissue Diseases
C0684249 BXGD009790 Carcinoma of lung Neoplasms; Respiratory Tract Diseases
C0686619 BXGD009835 Secondary malignant neoplasm of lymph node Pathological Conditions, Signs and Symptoms; Neoplasms
C0699790 BXGD009866 Colon Carcinoma Digestive System Diseases; Neoplasms
C0699791 BXGD009867 Stomach Carcinoma Digestive System Diseases; Neoplasms
C0699885 BXGD009869 Carcinoma of bladder Neoplasms; Female Urogenital Diseases and Pregnancy Complications; Male Urogenital Diseases
C0700095 BXGD009875 Central neuroblastoma Neoplasms; Nervous System Diseases
C0812413 BXGD010847 Malignant Pleural Mesothelioma Neoplasms; Respiratory Tract Diseases
C0853879 BXGD010982 Invasive carcinoma of breast Neoplasms; Skin and Connective Tissue Diseases
C0876973 BXGD011322 Infectious Lung Disorder Infections; Respiratory Tract Diseases
C0919267 BXGD011426 ovarian neoplasm Neoplasms; Female Urogenital Diseases and Pregnancy Complications; Endocrine System Diseases
C1140680 BXGD011718 Malignant neoplasm of ovary Neoplasms; Female Urogenital Diseases and Pregnancy Complications; Endocrine System Diseases
C1168401 BXGD011792 Squamous cell carcinoma of the head and neck Neoplasms
C1269955 BXGD012005 Tumor Cell Invasion
C1292753 BXGD012226 Primary Effusion Lymphoma Neoplasms; Immune System Diseases; Hemic and Lymphatic Diseases
C1306067 BXGD012353 Drug-induced paranoid state
C1306459 BXGD012361 Primary malignant neoplasm Neoplasms
C1306460 BXGD012362 Primary malignant neoplasm of lung Neoplasms; Respiratory Tract Diseases
C1328504 BXGD012469 Hormone refractory prostate cancer Neoplasms; Male Urogenital Diseases
C1332201 BXGD012502 Adult Diffuse Large B-Cell Lymphoma Neoplasms; Immune System Diseases; Hemic and Lymphatic Diseases
C1332206 BXGD012504 Adult Lymphoma Neoplasms; Immune System Diseases; Hemic and Lymphatic Diseases
C1332977 BXGD012569 Childhood Leukemia Neoplasms
C1332979 BXGD012571 Childhood Lymphoma Neoplasms; Immune System Diseases; Hemic and Lymphatic Diseases
C1332986 BXGD012574 Childhood Osteosarcoma Neoplasms
C1335302 BXGD012775 Pancreatic Ductal Adenocarcinoma Digestive System Diseases; Neoplasms; Endocrine System Diseases
C1368898 BXGD012904 Adult Teratoma Neoplasms
C1458155 BXGD013136 Mammary Neoplasms Neoplasms; Skin and Connective Tissue Diseases
C1512127 BXGD013185 HER2 gene amplification
C1516061 BXGD013211 Astler-Coller B1 Rectal Carcinoma
C1527390 BXGD013285 Neoplasms, Intracranial Neoplasms; Nervous System Diseases
C1535939 BXGD013323 Pneumocystis jiroveci pneumonia Infections; Respiratory Tract Diseases
C1608408 BXGD013434 Malignant transformation
C1621958 BXGD013468 Glioblastoma Multiforme Neoplasms
C1623038 BXGD013475 Cirrhosis Pathological Conditions, Signs and Symptoms
C1698088 BXGD013512 Malignant Solid Neoplasm Neoplasms
C1762616 BXGD013753 Meningioma, benign, no ICD-O subtype Neoplasms; Nervous System Diseases
C1832033 BXGD013795 Adult Subependymal Giant Cell Astrocytoma Neoplasms
C1832034 BXGD013796 Childhood Subependymal Giant Cell Astrocytoma Neoplasms
C1832661 BXGD013866 ANOPHTHALMIA AND PULMONARY HYPOPLASIA Congenital, Hereditary, and Neonatal Diseases and Abnormalities; Eye Diseases; Respiratory Tract Diseases
C1834582 BXGD013982 MYELOPROLIFERATIVE SYNDROME, TRANSIENT Congenital, Hereditary, and Neonatal Diseases and Abnormalities; Nervous System Diseases; Hemic and Lymphatic Diseases
C1861305 BXGD016027 TARSAL-CARPAL COALITION SYNDROME Congenital, Hereditary, and Neonatal Diseases and Abnormalities; Musculoskeletal Diseases
C1881254 BXGD016585 Inverted Squamous Cell Papilloma Neoplasms
C1955869 BXGD016612 Malformations of Cortical Development Congenital, Hereditary, and Neonatal Diseases and Abnormalities; Nervous System Diseases
C1960398 BXGD016658 HER2-positive carcinoma of breast Neoplasms; Skin and Connective Tissue Diseases
C1962942 BXGD016677 TRICHOMONAS VAGINALIS (finding)
C2062441 BXGD016897 Influenza A
C2239176 BXGD016965 Liver carcinoma Digestive System Diseases; Neoplasms
C2347762 BXGD017050 Childhood Teratoma Neoplasms
C2363741 BXGD017100 HIV-1 infection
C2675014 BXGD017263 Mullerian Aplasia and Hyperandrogenism Congenital, Hereditary, and Neonatal Diseases and Abnormalities; Female Urogenital Diseases and Pregnancy Complications; Male Urogenital Diseases; Endocrine System Diseases
C2676033 BXGD017322 Hepatoblastoma Caused By Somatic Mutation Digestive System Diseases; Neoplasms
C2717836 BXGD017510 Steroid Sulfatase Deficiency Disease Congenital, Hereditary, and Neonatal Diseases and Abnormalities; Nutritional and Metabolic Diseases; Skin and Connective Tissue Diseases
C2745900 BXGD017568 Promyelocytic leukemia
C2826323 BXGD017790 Refractory Cytopenia of Childhood
C2931822 BXGD018068 Nasopharyngeal carcinoma Neoplasms; Stomatognathic Diseases; Otorhinolaryngologic Diseases
C2938924 BXGD018167 Oestrogen receptor positive breast cancer
C2939419 BXGD018178 Secondary Neoplasm Pathological Conditions, Signs and Symptoms; Neoplasms
C3146252 BXGD018261 Stage II Colorectal Cancer AJCC v7
C3160887 BXGD018489 Node-positive breast cancer
C3164407 BXGD018528 Oligoasthenozoospermia
C3266262 BXGD018600 Multiple Chronic Conditions Pathological Conditions, Signs and Symptoms
C3469521 BXGD018910 FANCONI ANEMIA, COMPLEMENTATION GROUP A (disorder) Congenital, Hereditary, and Neonatal Diseases and Abnormalities; Nutritional and Metabolic Diseases; Hemic and Lymphatic Diseases
C3539878 BXGD019087 Triple Negative Breast Neoplasms Neoplasms; Skin and Connective Tissue Diseases
C3888194 BXGD019955 MIXED LINEAGE LEUKEMIA
C4048328 BXGD021903 cervical cancer Neoplasms; Female Urogenital Diseases and Pregnancy Complications
C4049446 BXGD021933 Neointimal hyperplasia
C4086165 BXGD022126 Childhood Neuroblastoma Neoplasms
C4479709 BXGD022952 FCD IIB
C4521042 BXGD023055 Complete Trisomy 21 Syndrome Pathological Conditions, Signs and Symptoms; Congenital, Hereditary, and Neonatal Diseases and Abnormalities; Nervous System Diseases
C4688336 BXGD023587 Childhood Malignant Solid Neoplasm
C4704874 BXGD023682 Mammary Carcinoma, Human Neoplasms; Skin and Connective Tissue Diseases
C4721610 BXGD023760 Carcinoma, Ovarian Epithelial Neoplasms; Female Urogenital Diseases and Pregnancy Complications; Endocrine System Diseases
C4722085 BXGD023788 Malignant neoplasm of colon and/or rectum
C4722518 BXGD023806 Triple-Negative Breast Carcinoma Neoplasms; Skin and Connective Tissue Diseases
Target protein-related  compounds
Compounds
BXGC Id Compound Name Strcuture Molecular Weight
BXGC0000332 Fisetin 286.24
BXGC0000340 Kaempferol 286.24
BXGC0001545 Harmine 212.25
BXGC0002071 Apigenin 270.24
BXGC0002883 Myrosin 154.12
BXGC0003981 2,6-Diaminopurine 150.14
BXGC0004342 (E)-3-(2-Hydroxyphenyl)-2-propenal 148.16
BXGC0005624 Genistein 270.24
BXGC0005683 Quercetin 302.24
BXGC0005793 Baicalein 270.24
BXGC0006389 Rotenone 394.42
BXGC0006635 Luteolin 286.24
BXGC0007052 Olomoucine 298.34
BXGC0008167 Chrysin 254.24
BXGC0010354 Cytokinin B 225.25
BXGC0012352 Chelerythrine 348.12
BXGC0021578 n.a 262.07
BXGC0021676 Withaferin A 470.27
BXGC0023872 Adenine 135.05
BXGC0027547 Indigo 262.07
BXGC0028863 Atolaphyllidine 309.1
BXGC0031558 Baicalin 446.08
BXGC0037687 (4S)-2-methylpentane-2,4-diol 118.1
BXGC0038007 Aristolactam Aiiia 281.07
BXGC0038970 Hymenialdisine 323
BXGC0040305 Indirubin 262.07
BXGC0042376 Picropodophyllotoxin 414.13
BXGC0044857 Sp-600125 220.06
BXGC0045254 Sb-202190 331.11
BXGC0046919 debromohymenialdisine 245.09
BXGC0047692 Gefitinib 446.15
BXGC0048801 Sid24823998 254.09
BXGC0049956 n.a 262.07
BXGC0050099 (2E,5S,6S,8Z,11S)-5,6,15-Trihydroxy-17-Methoxy-11-Methyl-12-Oxabicyclo[12.4.0]Octadeca-1(14),2,8,15,17-Pentaene-7,13-Dione 362.14
The  target protein-related  foods
Foods
BXGF Id Food Name Scientific Name Food Group Number of compound? Number of compound in food, higher numbers indicate the food are more associated with the protein