acompound

Showing entry for Lumazine

　　　　　　　　　　　　　　　

General Compound Information
BXGC Id	BXGC0003398
Compound Name	Lumazine
Structure
Formula	C6H4N4O2
InchiKey	UYEUUXMDVNYCAM-UHFFFAOYSA-N
SMILES	O=C1NC(=O)C2=NC=CNC2=N1
Inchi	InChI=1S/C6H4N4O2/c11-5-3-4(8-2-1-7-3)9-6(12)10-5/h1-2H,(H2,8,9,10,11,12)
IUPAC	2,3,4,8-tetrahydropteridine-2,4-dione
Molecular Weight	164.12
Pubchem Id	10250
Chembl Id	CHEMBL1234104

Targets of Information Source

DrugBank

n.a

Uniport Id	BXGT Id	Protein Name	Status	Protein Class	Gene	Groups	Target Type
Uniport Id	BXGT Id	Protein Name	Status	Protein Class	Gene	Groups	Target Type

PDB

Uniport Id	BXGT Id	Protein Name	Status	Protein Class	Gene	Ki nM	ic50 nM	Kd nM	Ka M-1
Uniport Id	BXGT Id	Protein Name	Status	Protein Class	Gene	Ki nM	ic50 nM	Kd nM	Ka M-1
P80457	BXGT011911	Xanthine dehydrogenase/oxidase	reviewed	XDH	-	-	-	-	-
Q6B0I6	BXGT016211	Lysine-specific demethylase 4D	reviewed	KDM4D	Epigenetic regulator	-	-	-	-
P42336	BXGT010302	Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit alpha isoform	reviewed	PIK3CA	Kinase	-	-	-	-

Binding DB

n.a

Uniport Id	BXGT Id	Protein Name	Status	Protein Class	Gene	Ki nM	ic50 nM	Kd nM	EC50 nM
Uniport Id	BXGT Id	Protein Name	Status	Protein Class	Gene	Ki nM	ic50 nM	Kd nM	EC50 nM

CHEMBL

Uniport Id	BXGT Id	Protein Name	Status	Protein Class	Gene	width="10%">Type	Relation	value	Units
Uniport Id	BXGT Id	Protein Name	Status	Protein Class	Gene	Type	Relation	value	Units
P42336	BXGT010302	Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit alpha isoform	reviewed	Kinase	PIK3CA	Inhibition	'<'	25	%
P42336	BXGT010302	Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit alpha isoform	reviewed	Kinase	PIK3CA	Inhibition	'<'	25	%
P27986	BXGT009216	Phosphatidylinositol 3-kinase regulatory subunit alpha	reviewed	Kinase	PIK3R1	Inhibition	'<'	25	%

Foods containing the compound

Foods

BXGF Id	Food Name	Scientific Name	Food Group
BXGF Id	Food Name	Scientific Name	Food Group
BXGF00085	Soy bean	Glycine max	Soy

The compound-realted diseases

Diseases

BXGD Id	Disease Name	CUI Disease Id	Disease Class Name	Number of targets^{?Number of targets related to compound connecting disease, higher numbers indicate the compound is more associated with the disease}