acompound

Showing entry for (R)-Higenamine

　　　　　　　　　　　　　　　

General Compound Information
BXGC Id	BXGC0005155
Compound Name	(R)-Higenamine
Structure
Formula	C16H17NO3
InchiKey	WZRCQWQRFZITDX-UHFFFAOYSA-N
SMILES	OC1=CC=C(CC2NCCC3=C2C=C(O)C(O)=C3)C=C1
Inchi	InChI=1S/C16H17NO3/c18-12-3-1-10(2-4-12)7-14-13-9-16(20)15(19)8-11(13)5-6-17-14/h1-4,8-9,14,17-20H,5-7H2
IUPAC	1-[(4-hydroxyphenyl)methyl]-1,2,3,4-tetrahydroisoquinoline-6,7-diol
Molecular Weight	271.31
Pubchem Id	114840
Chembl Id	CHEMBL19344

Targets of Information Source

DrugBank

n.a

Uniport Id	BXGT Id	Protein Name	Status	Protein Class	Gene	Groups	Target Type
Uniport Id	BXGT Id	Protein Name	Status	Protein Class	Gene	Groups	Target Type

PDB

n.a

Uniport Id	BXGT Id	Protein Name	Status	Protein Class	Gene	Ki nM	ic50 nM	Kd nM	Ka M-1
Uniport Id	BXGT Id	Protein Name	Status	Protein Class	Gene	Ki nM	ic50 nM	Kd nM	Ka M-1

Binding DB

n.a

Uniport Id	BXGT Id	Protein Name	Status	Protein Class	Gene	Ki nM	ic50 nM	Kd nM	EC50 nM
Uniport Id	BXGT Id	Protein Name	Status	Protein Class	Gene	Ki nM	ic50 nM	Kd nM	EC50 nM

CHEMBL

Uniport Id	BXGT Id	Protein Name	Status	Protein Class	Gene	width="10%">Type	Relation	value	Units
Uniport Id	BXGT Id	Protein Name	Status	Protein Class	Gene	Type	Relation	value	Units
P14416	BXGT008011	D(2) dopamine receptor	reviewed	G-protein coupled receptor	DRD2	Ki	'='	3900	nM
P21917	BXGT008707	D(4) dopamine receptor	reviewed	G-protein coupled receptor	DRD4	Ki	'='	3100	nM
P21917	BXGT008707	D(4) dopamine receptor	reviewed	G-protein coupled receptor	DRD4	Ratio	'='	1	-
P14416	BXGT008011	D(2) dopamine receptor	reviewed	G-protein coupled receptor	DRD2	Ratio	'='	1	-
P10608	BXGT007586	Beta-2 adrenergic receptor	reviewed	-	Adrb2	FC	'>'	2	-
P10608	BXGT007586	Beta-2 adrenergic receptor	reviewed	-	Adrb2	Activity	-	-	-

Foods containing the compound

Foods

BXGF Id	Food Name	Scientific Name	Food Group
BXGF Id	Food Name	Scientific Name	Food Group
BXGF00014	Custard apple	Annona reticulata	Fruits
BXGF00369	Sacred lotus	Nelumbo nucifera	Vegetables
BXGF00402	Opium poppy	Papaver somniferum	Herbs and Spices
BXGF00813	Coffee and coffee products		Coffee and coffee products
BXGF01885	Aconitum triphyllum	Aconitum triphyllum	Others
BXGF04920	Aconitum carmichaeli	Aconitum carmichaeli	Medicinal Plant
BXGF05360	Aconitum ciliare	Aconitum ciliare	Others
BXGF05365	Aconitum carmichaelii	Aconitum carmichaelii	Medicinal Plant
BXGF05627	Asarum sieboldii	Asarum sieboldii	Medicinal Plant
BXGF05851	Aconitum japonicum	Aconitum japonicum	Medicinal Plant
BXGF06106	Aconitum kusnezoffii	Aconitum kusnezoffii	Others

The compound-realted diseases

Diseases

BXGD Id	Disease Name	CUI Disease Id	Disease Class Name	Number of targets^{?Number of targets related to compound connecting disease, higher numbers indicate the compound is more associated with the disease}