Showing entry for Beta-2 adrenergic receptor


　 　 　 　 　 　 　 　 　 　 　 　
General Target Information
BXGT IdBXGT007586
Protein NameBeta-2 adrenergic receptor
Uniport IdP10608
GeneAdrb2
Gene Id
Domain7tm_1
Pfam PF00001  
OrganismRattus norvegicus (Rat)
Target protein  affiliated  biological  pathways
KEGG
Class Subclass KEGG Id Pathway Name
Gene Ontology
GO Type GO Id Gene Ontology
Biological Process GO:0007190 activation of adenylate cyclase activity
Biological Process GO:0071880 adenylate cyclase-activating adrenergic receptor signaling pathway
Biological Process GO:0007189 adenylate cyclase-activating G protein-coupled receptor signaling pathway
Biological Process GO:0007188 adenylate cyclase-modulating G protein-coupled receptor signaling pathway
Biological Process GO:0071875 adrenergic receptor signaling pathway
Biological Process GO:0007568 aging
Biological Process GO:0008306 associative learning
Biological Process GO:0045453 bone resorption
Biological Process GO:0050873 brown fat cell differentiation
Biological Process GO:1904646 cellular response to amyloid-beta
Biological Process GO:0071456 cellular response to hypoxia
Biological Process GO:0002032 desensitization of G protein-coupled receptor signaling pathway by arrestin
Biological Process GO:0002086 diaphragm contraction
Biological Process GO:0002024 diet induced thermogenesis
Biological Process GO:0044849 estrous cycle
Biological Process GO:0060079 excitatory postsynaptic potential
Biological Process GO:0007565 female pregnancy
Biological Process GO:0007186 G protein-coupled receptor signaling pathway
Biological Process GO:0031649 heat generation
Biological Process GO:0001889 liver development
Biological Process GO:0097421 liver regeneration
Biological Process GO:0016525 negative regulation of angiogenesis
Biological Process GO:0050728 negative regulation of inflammatory response
Biological Process GO:0040015 negative regulation of multicellular organism growth
Biological Process GO:0030279 negative regulation of ossification
Biological Process GO:0090331 negative regulation of platelet aggregation
Biological Process GO:0045986 negative regulation of smooth muscle contraction
Biological Process GO:0035811 negative regulation of urine volume
Biological Process GO:0002025 norepinephrine-epinephrine-mediated vasodilation involved in regulation of systemic arterial blood pressure
Biological Process GO:2000969 positive regulation of AMPA receptor activity
Biological Process GO:0043065 positive regulation of apoptotic process
Biological Process GO:0032781 positive regulation of ATPase activity
Biological Process GO:1901098 positive regulation of autophagosome maturation
Biological Process GO:0097755 positive regulation of blood vessel diameter
Biological Process GO:0030501 positive regulation of bone mineralization
Biological Process GO:1905665 positive regulation of calcium ion import across plasma membrane
Biological Process GO:0008284 positive regulation of cell population proliferation
Biological Process GO:0120162 positive regulation of cold-induced thermogenesis
Biological Process GO:0045823 positive regulation of heart contraction
Biological Process GO:1904504 positive regulation of lipophagy
Biological Process GO:0043410 positive regulation of MAPK cascade
Biological Process GO:0061885 positive regulation of mini excitatory postsynaptic potential
Biological Process GO:0043268 positive regulation of potassium ion transport
Biological Process GO:0010739 positive regulation of protein kinase A signaling
Biological Process GO:0071902 positive regulation of protein serine/threonine kinase activity
Biological Process GO:0031398 positive regulation of protein ubiquitination
Biological Process GO:0048633 positive regulation of skeletal muscle tissue growth
Biological Process GO:0010765 positive regulation of sodium ion transport
Biological Process GO:0003059 positive regulation of the force of heart contraction by epinephrine
Biological Process GO:0045944 positive regulation of transcription by RNA polymerase II
Biological Process GO:0006898 receptor-mediated endocytosis
Biological Process GO:0051924 regulation of calcium ion transport
Biological Process GO:0051930 regulation of sensory perception of pain
Biological Process GO:0002028 regulation of sodium ion transport
Biological Process GO:2000300 regulation of synaptic vesicle exocytosis
Biological Process GO:0001993 regulation of systemic arterial blood pressure by norepinephrine-epinephrine
Biological Process GO:0009409 response to cold
Biological Process GO:0071548 response to dexamethasone
Biological Process GO:0043627 response to estrogen
Biological Process GO:0001666 response to hypoxia
Biological Process GO:0071867 response to monoamine
Biological Process GO:0032570 response to progesterone
Biological Process GO:0033574 response to testosterone
Biological Process GO:0035249 synaptic transmission, glutamatergic
Biological Process GO:0042060 wound healing
molecular function GO:0008179 adenylate cyclase binding
molecular function GO:0001540 amyloid-beta binding
molecular function GO:0031713 B2 bradykinin receptor binding
molecular function GO:0004941 beta2-adrenergic receptor activity
molecular function GO:0035240 dopamine binding
molecular function GO:0008144 drug binding
molecular function GO:0019899 enzyme binding
molecular function GO:0051379 epinephrine binding
molecular function GO:0001965 G-protein alpha-subunit binding
molecular function GO:0004930 G protein-coupled receptor activity
molecular function GO:0042802 identical protein binding
molecular function GO:0035255 ionotropic glutamate receptor binding
molecular function GO:0051380 norepinephrine binding
molecular function GO:0030165 PDZ domain binding
molecular function GO:0015459 potassium channel regulator activity
molecular function GO:0044877 protein-containing complex binding
molecular function GO:0042803 protein homodimerization activity
molecular function GO:0051721 protein phosphatase 2A binding
molecular function GO:0090722 receptor-receptor interaction
cellular component GO:0016324 apical plasma membrane
cellular component GO:0030424 axon
cellular component GO:0005901 caveola
cellular component GO:0005737 cytoplasm
cellular component GO:0030425 dendrite
cellular component GO:0043197 dendritic spine
cellular component GO:0005769 early endosome
cellular component GO:0005768 endosome
cellular component GO:0098978 glutamatergic synapse
cellular component GO:0005887 integral component of plasma membrane
cellular component GO:0043231 intracellular membrane-bounded organelle
cellular component GO:0016020 membrane
cellular component GO:0032809 neuronal cell body membrane
cellular component GO:0005634 nucleus
cellular component GO:0005886 plasma membrane
cellular component GO:0043235 receptor complex
cellular component GO:0042383 sarcolemma
Reactome
Pathway Id Pathway Name
Target protein-related  diseases
Disease
CUI Id BXGD Id Disease Name Disease Class
Target protein-related  compounds
Compounds
BXGC Id Compound Name Strcuture Molecular Weight
BXGC0000538 (R)-Norepinephrine 169.18
BXGC0000982 L-Homocysteine 135.19
BXGC0005155 (R)-Higenamine 271.31
BXGC0005683 Quercetin 302.24
BXGC0005874 Racemethionine 149.21
BXGC0006183 L-Cystine 240.3
BXGC0007467 alpha-Terpineol 154.25
BXGC0018063 Alprenolol 249.17
BXGC0021893 Norepinephrine 169.07
BXGC0022038 (+)-Higenamine 271.12
BXGC0028991 (-)-Higenamine 271.12
BXGC0031384 Epinephrine 183.09
BXGC0038837 Pseudohypericin 520.08
BXGC0041240 Atenolol 266.16
BXGC0042222 Propranolol 259.16
BXGC0042462 Cysteine 121.02
BXGC0042510 Fluoxetine 309.13
The  target protein-related  foods
Foods
BXGF Id Food Name Scientific Name Food Group Number of compound? Number of compound in food, higher numbers indicate the food are more associated with the protein