acompound

Showing entry for (Z)-4',6-Dihydroxyaurone

　　　　　　　　　　　　　　　

General Compound Information
BXGC Id	BXGC0005186
Compound Name	(Z)-4',6-Dihydroxyaurone
Structure
Formula	C15H10O4
InchiKey	KEZLDSPIRVZOKZ-AUWJEWJLSA-N
SMILES	OC1=CC=C(\C=C2/OC3=C(C=CC(O)=C3)C2=O)C=C1
Inchi	InChI=1S/C15H10O4/c16-10-3-1-9(2-4-10)7-14-15(18)12-6-5-11(17)8-13(12)19-14/h1-8,16-17H/b14-7-
IUPAC	(2Z)-6-hydroxy-2-[(4-hydroxyphenyl)methylidene]-2,3-dihydro-1-benzofuran-3-one
Molecular Weight	254.24
Pubchem Id	5281254
Chembl Id	CHEMBL426110

Targets of Information Source

DrugBank

n.a

Uniport Id	BXGT Id	Protein Name	Status	Protein Class	Gene	Groups	Target Type
Uniport Id	BXGT Id	Protein Name	Status	Protein Class	Gene	Groups	Target Type

PDB

n.a

Uniport Id	BXGT Id	Protein Name	Status	Protein Class	Gene	Ki nM	ic50 nM	Kd nM	Ka M-1
Uniport Id	BXGT Id	Protein Name	Status	Protein Class	Gene	Ki nM	ic50 nM	Kd nM	Ka M-1

Binding DB

Uniport Id	BXGT Id	Protein Name	Status	Protein Class	Gene	Ki nM	ic50 nM	Kd nM	EC50 nM
Uniport Id	BXGT Id	Protein Name	Status	Protein Class	Gene	Ki nM	ic50 nM	Kd nM	EC50 nM
reviewed	BXGT008039	Tyrosinase	reviewed	Enzyme	TYR	-	38400	-	-

CHEMBL

Uniport Id	BXGT Id	Protein Name	Status	Protein Class	Gene	width="10%">Type	Relation	value	Units
Uniport Id	BXGT Id	Protein Name	Status	Protein Class	Gene	Type	Relation	value	Units
P15559	BXGT008139	NAD(P)H dehydrogenase [quinone] 1	reviewed	-	NQO1	FC	'='	1	-
P14679	BXGT008039	Tyrosinase	reviewed	Enzyme	TYR	IC50	'='	38400	nM
P15559	BXGT008139	NAD(P)H dehydrogenase [quinone] 1	reviewed	-	NQO1	FC	'='	1	-
P14679	BXGT008039	Tyrosinase	reviewed	Enzyme	TYR	Inhibition	'='	69	%
P27338	BXGT009172	Amine oxidase [flavin-containing] B	reviewed	-	MAOB	Activity	'='	28	%
P27338	BXGT009172	Amine oxidase [flavin-containing] B	reviewed	-	MAOB	Activity	'='	87	%
P21397	BXGT008644	Amine oxidase [flavin-containing] A	reviewed	-	MAOA	Inhibition	'='	83	%
P27338	BXGT009172	Amine oxidase [flavin-containing] B	reviewed	-	MAOB	Ki	'='	510	nM
P21397	BXGT008644	Amine oxidase [flavin-containing] A	reviewed	-	MAOA	Inhibition	'='	29	%
P27338	BXGT009172	Amine oxidase [flavin-containing] B	reviewed	-	MAOB	IC50	'='	2450	nM
P21397	BXGT008644	Amine oxidase [flavin-containing] A	reviewed	-	MAOA	IC50	'='	260	nM
P21397	BXGT008644	Amine oxidase [flavin-containing] A	reviewed	-	MAOA	Ki	'='	100	nM
P21397	BXGT008644	Amine oxidase [flavin-containing] A	reviewed	-	MAOA	TDI	-	-	-

Foods containing the compound

Foods

BXGF Id	Food Name	Scientific Name	Food Group
BXGF Id	Food Name	Scientific Name	Food Group
BXGF00085	Soy bean	Glycine max	Soy
BXGF00819	Pulses		Pulses

The compound-realted diseases

Diseases

BXGD Id	Disease Name	CUI Disease Id	Disease Class Name	Number of targets^{?Number of targets related to compound connecting disease, higher numbers indicate the compound is more associated with the disease}