Showing entry for Tyrosinase


　 　 　 　 　 　 　 　 　 　 　 　
General Target Information
BXGT IdBXGT008039
Protein NameTyrosinase
Uniport IdP14679
GeneTYR
Gene Id7299
DomainTyrosinase
Pfam PF00264  
OrganismHomo sapiens (Human)
Target protein  affiliated  biological  pathways
KEGG
Class Subclass KEGG Id Pathway Name
1. Metabolism 1.5 Amino acid metabolism hsa00350 Tyrosine metabolism
1. Metabolism 1.0 Global and overview maps hsa01100 Metabolic pathways
5. Organismal Systems 5.2 Endocrine system hsa04916 Melanogenesis
Gene Ontology
GO Type GO Id Gene Ontology
Biological Process GO:0008283 cell population proliferation
Biological Process GO:0006726 eye pigment biosynthetic process
Biological Process GO:0042438 melanin biosynthetic process
Biological Process GO:0006583 melanin biosynthetic process from tyrosine
Biological Process GO:0043473 pigmentation
Biological Process GO:0009637 response to blue light
Biological Process GO:0051591 response to cAMP
Biological Process GO:0009411 response to UV
Biological Process GO:0033280 response to vitamin D
Biological Process GO:0048538 thymus development
Biological Process GO:0007601 visual perception
molecular function GO:0005507 copper ion binding
molecular function GO:0042802 identical protein binding
molecular function GO:0004503 monophenol monooxygenase activity
molecular function GO:0042803 protein homodimerization activity
cellular component GO:0005737 cytoplasm
cellular component GO:0005829 cytosol
cellular component GO:0005798 Golgi-associated vesicle
cellular component GO:0016021 integral component of membrane
cellular component GO:0043231 intracellular membrane-bounded organelle
cellular component GO:0005764 lysosome
cellular component GO:0042470 melanosome
cellular component GO:0033162 melanosome membrane
cellular component GO:0005634 nucleus
cellular component GO:0048471 perinuclear region of cytoplasm
Reactome
Pathway Id Pathway Name
R-HSA-1430728 Metabolism
R-HSA-5662702 Melanin biosynthesis
R-HSA-71291 Metabolism of amino acids and derivatives
Target protein-related  diseases
Disease
CUI Id BXGD Id Disease Name Disease Class
C0000768 BXGD000007 Congenital Abnormality Congenital, Hereditary, and Neonatal Diseases and Abnormalities
C0001916 BXGD000089 Albinism Congenital, Hereditary, and Neonatal Diseases and Abnormalities; Nutritional and Metabolic Diseases; Eye Diseases; Skin and Connective Tissue Diseases
C0001973 BXGD000095 Alcoholic Intoxication, Chronic Chemically-Induced Disorders; Mental Disorders
C0002395 BXGD000111 Alzheimer's Disease Nervous System Diseases; Mental Disorders
C0002793 BXGD000130 Anaplasia Pathological Conditions, Signs and Symptoms; Neoplasms
C0002965 BXGD000162 Angina, Unstable Pathological Conditions, Signs and Symptoms; Cardiovascular Diseases
C0004106 BXGD000254 Astigmatism Eye Diseases
C0004135 BXGD000257 Ataxia Telangiectasia Congenital, Hereditary, and Neonatal Diseases and Abnormalities; Nutritional and Metabolic Diseases; Immune System Diseases; Nervous System Diseases; Cardiovascular Diseases
C0004364 BXGD000270 Autoimmune Diseases Immune System Diseases
C0004565 BXGD000276 Melanoma, B16 Neoplasms
C0004936 BXGD000295 Mental disorders Mental Disorders
C0005586 BXGD000315 Bipolar Disorder Mental Disorders
C0006118 BXGD000372 Brain Neoplasms Neoplasms; Nervous System Diseases
C0006142 BXGD000374 Malignant neoplasm of breast Neoplasms; Skin and Connective Tissue Diseases
C0006826 BXGD000408 Malignant Neoplasms Neoplasms
C0007114 BXGD000431 Malignant neoplasm of skin Neoplasms; Skin and Connective Tissue Diseases
C0007117 BXGD000433 Basal cell carcinoma Neoplasms
C0007129 BXGD000439 Merkel cell carcinoma Neoplasms; Infections
C0007131 BXGD000441 Non-Small Cell Lung Carcinoma Neoplasms; Respiratory Tract Diseases
C0007137 BXGD000445 Squamous cell carcinoma Neoplasms
C0007965 BXGD000508 Chediak-Higashi Syndrome Congenital, Hereditary, and Neonatal Diseases and Abnormalities; Eye Diseases; Immune System Diseases; Hemic and Lymphatic Diseases
C0008073 BXGD000518 Developmental Disabilities Mental Disorders
C0008626 BXGD000559 Congenital chromosomal disease Congenital, Hereditary, and Neonatal Diseases and Abnormalities
C0009763 BXGD000628 Conjunctivitis Eye Diseases
C0010674 BXGD000683 Cystic Fibrosis Congenital, Hereditary, and Neonatal Diseases and Abnormalities; Digestive System Diseases; Respiratory Tract Diseases
C0010823 BXGD000690 Cytomegalovirus Infections Infections
C0011603 BXGD000734 Dermatitis Skin and Connective Tissue Diseases
C0011615 BXGD000738 Dermatitis, Atopic Congenital, Hereditary, and Neonatal Diseases and Abnormalities; Skin and Connective Tissue Diseases; Immune System Diseases
C0013274 BXGD000809 Patent ductus arteriosus Congenital, Hereditary, and Neonatal Diseases and Abnormalities; Cardiovascular Diseases
C0013595 BXGD000858 Eczema Skin and Connective Tissue Diseases
C0015310 BXGD000976 Exotropia Eye Diseases; Nervous System Diseases
C0015396 BXGD000982 Eye Color
C0015397 BXGD000983 Disorder of eye Eye Diseases
C0016689 BXGD001073 Freckles Skin and Connective Tissue Diseases
C0017601 BXGD001125 Glaucoma Eye Diseases
C0017636 BXGD001131 Glioblastoma Neoplasms
C0018498 BXGD001195 Hair Color
C0018784 BXGD001220 Sensorineural Hearing Loss (disorder) Pathological Conditions, Signs and Symptoms; Nervous System Diseases; Otorhinolaryngologic Diseases
C0018802 BXGD001227 Congestive heart failure Cardiovascular Diseases
C0018923 BXGD001248 Hemangiosarcoma Neoplasms
C0019202 BXGD001302 Hepatolenticular Degeneration Congenital, Hereditary, and Neonatal Diseases and Abnormalities; Digestive System Diseases; Nutritional and Metabolic Diseases; Nervous System Diseases
C0019212 BXGD001306 Hepatorenal Syndrome Digestive System Diseases; Female Urogenital Diseases and Pregnancy Complications; Male Urogenital Diseases
C0019348 BXGD001325 Herpes Simplex Infections Infections; Skin and Connective Tissue Diseases
C0019880 BXGD001351 Homocystinuria Congenital, Hereditary, and Neonatal Diseases and Abnormalities; Nutritional and Metabolic Diseases; Skin and Connective Tissue Diseases; Nervous System Diseases
C0020302 BXGD001373 Hydrophthalmos Congenital, Hereditary, and Neonatal Diseases and Abnormalities; Eye Diseases
C0020490 BXGD001403 Hyperopia Eye Diseases
C0021400 BXGD001504 Influenza Infections; Respiratory Tract Diseases
C0022078 BXGD001526 Iris Diseases Eye Diseases
C0022602 BXGD001564 Actinic keratosis Neoplasms; Skin and Connective Tissue Diseases
C0022603 BXGD001565 Seborrheic keratosis Skin and Connective Tissue Diseases
C0022660 BXGD001571 Kidney Failure, Acute Female Urogenital Diseases and Pregnancy Complications; Male Urogenital Diseases
C0022672 BXGD001574 Acute Kidney Tubular Necrosis Female Urogenital Diseases and Pregnancy Complications; Male Urogenital Diseases
C0023321 BXGD001634 Lentigo Skin and Connective Tissue Diseases
C0023418 BXGD001642 leukemia Neoplasms
C0023465 BXGD001656 Acute monocytic leukemia Neoplasms
C0023467 BXGD001658 Leukemia, Myelocytic, Acute Neoplasms
C0023470 BXGD001659 Myeloid Leukemia Neoplasms
C0023492 BXGD001671 Leukemia, T-Cell Neoplasms; Immune System Diseases; Hemic and Lymphatic Diseases
C0023493 BXGD001672 Adult T-Cell Lymphoma/Leukemia Neoplasms; Immune System Diseases; Hemic and Lymphatic Diseases
C0023520 BXGD001678 Leukodystrophy Congenital, Hereditary, and Neonatal Diseases and Abnormalities; Nutritional and Metabolic Diseases; Nervous System Diseases
C0023890 BXGD001713 Liver Cirrhosis Pathological Conditions, Signs and Symptoms; Digestive System Diseases
C0024141 BXGD001740 Lupus Erythematosus, Systemic Skin and Connective Tissue Diseases; Immune System Diseases
C0024440 BXGD001774 Macular Edema, Cystoid Eye Diseases
C0025202 BXGD001832 melanoma Neoplasms
C0025209 BXGD001834 Melanosis Skin and Connective Tissue Diseases
C0025218 BXGD001836 Chloasma Skin and Connective Tissue Diseases
C0025517 BXGD001875 Metabolic Diseases Nutritional and Metabolic Diseases
C0026010 BXGD001886 Microphthalmos Congenital, Hereditary, and Neonatal Diseases and Abnormalities; Eye Diseases
C0026769 BXGD001930 Multiple Sclerosis Immune System Diseases; Nervous System Diseases
C0027051 BXGD001963 Myocardial Infarction Pathological Conditions, Signs and Symptoms; Cardiovascular Diseases
C0027092 BXGD001971 Myopia Eye Diseases
C0027627 BXGD002006 Neoplasm Metastasis Pathological Conditions, Signs and Symptoms; Neoplasms
C0027651 BXGD002009 Neoplasms Neoplasms
C0027809 BXGD002040 Neurilemmoma Neoplasms
C0027819 BXGD002043 Neuroblastoma Neoplasms
C0027962 BXGD002064 Melanocytic nevus Neoplasms
C0028738 BXGD002081 Nystagmus Eye Diseases; Nervous System Diseases
C0029131 BXGD002116 Abnormality of the optic nerve
C0030354 BXGD002214 Papilloma Neoplasms
C0030567 BXGD002240 Parkinson Disease Nervous System Diseases
C0031039 BXGD002274 Pericardial effusion Cardiovascular Diseases
C0032897 BXGD002378 Prader-Willi Syndrome Congenital, Hereditary, and Neonatal Diseases and Abnormalities; Nutritional and Metabolic Diseases; Nervous System Diseases
C0033860 BXGD002438 Psoriasis Skin and Connective Tissue Diseases
C0033975 BXGD002447 Psychotic Disorders Mental Disorders
C0035300 BXGD002526 Abnormal retinal morphology Eye Diseases
C0035305 BXGD002529 Retinal Detachment Eye Diseases
C0035335 BXGD002540 Retinoblastoma Neoplasms; Eye Diseases
C0036341 BXGD002600 Schizophrenia Mental Disorders
C0036651 BXGD002628 Solar lentigo Pathological Conditions, Signs and Symptoms; Skin and Connective Tissue Diseases
C0037274 BXGD002676 Dermatologic disorders Skin and Connective Tissue Diseases
C0037278 BXGD002678 Skin Diseases, Infectious Infections; Skin and Connective Tissue Diseases
C0037284 BXGD002679 Skin lesion Skin and Connective Tissue Diseases
C0037286 BXGD002681 Skin Neoplasms Neoplasms; Skin and Connective Tissue Diseases
C0037290 BXGD002683 Skin Pigmentation
C0037354 BXGD002690 Smallpox Infections
C0038379 BXGD002752 Strabismus Eye Diseases; Nervous System Diseases
C0040420 BXGD002861 Tonometry
C0040517 BXGD002872 Gilles de la Tourette syndrome Congenital, Hereditary, and Neonatal Diseases and Abnormalities; Nervous System Diseases; Mental Disorders
C0040997 BXGD002894 Trigeminal Neuralgia Nervous System Diseases; Stomatognathic Diseases
C0041341 BXGD002918 Tuberous Sclerosis Congenital, Hereditary, and Neonatal Diseases and Abnormalities; Neoplasms; Nervous System Diseases
C0042170 BXGD002969 Uveomeningoencephalitic Syndrome Eye Diseases; Immune System Diseases; Nervous System Diseases
C0042842 BXGD003005 Vitamin A Deficiency Nutritional and Metabolic Diseases
C0042900 BXGD003012 Vitiligo Skin and Connective Tissue Diseases
C0078917 BXGD003054 Albinism, Ocular Congenital, Hereditary, and Neonatal Diseases and Abnormalities; Nutritional and Metabolic Diseases; Eye Diseases; Skin and Connective Tissue Diseases
C0078918 BXGD003055 Albinism, Oculocutaneous Congenital, Hereditary, and Neonatal Diseases and Abnormalities; Nutritional and Metabolic Diseases; Eye Diseases; Skin and Connective Tissue Diseases
C0078921 BXGD003056 Albinism, Tyrosinase-Negative Congenital, Hereditary, and Neonatal Diseases and Abnormalities; Nutritional and Metabolic Diseases; Eye Diseases; Skin and Connective Tissue Diseases
C0078922 BXGD003057 Albinism, Tyrosinase-Positive Congenital, Hereditary, and Neonatal Diseases and Abnormalities; Nutritional and Metabolic Diseases; Eye Diseases; Skin and Connective Tissue Diseases
C0078923 BXGD003058 Albinism, Yellow-Mutant Congenital, Hereditary, and Neonatal Diseases and Abnormalities; Nutritional and Metabolic Diseases; Eye Diseases; Skin and Connective Tissue Diseases
C0079504 BXGD003080 Hermanski-Pudlak Syndrome Congenital, Hereditary, and Neonatal Diseases and Abnormalities; Nutritional and Metabolic Diseases; Eye Diseases; Skin and Connective Tissue Diseases; Hemic and Lymphatic Diseases
C0080024 BXGD003104 Piebaldism Congenital, Hereditary, and Neonatal Diseases and Abnormalities; Nutritional and Metabolic Diseases; Skin and Connective Tissue Diseases
C0085136 BXGD003131 Central Nervous System Neoplasms Neoplasms; Nervous System Diseases
C0085636 BXGD003218 Photophobia Pathological Conditions, Signs and Symptoms; Eye Diseases; Nervous System Diseases
C0085669 BXGD003233 Acute leukemia Pathological Conditions, Signs and Symptoms; Neoplasms
C0086543 BXGD003294 Cataract Eye Diseases
C0151779 BXGD003473 Cutaneous Melanoma Neoplasms; Skin and Connective Tissue Diseases
C0151891 BXGD003499 Retinal depigmentation Pathological Conditions, Signs and Symptoms; Eye Diseases; Skin and Connective Tissue Diseases
C0152459 BXGD003600 Linear atrophy Pathological Conditions, Signs and Symptoms
C0153535 BXGD003661 Malignant melanoma of skin of upper limb Neoplasms; Skin and Connective Tissue Diseases
C0153536 BXGD003662 Malignant melanoma of skin of lower limb Neoplasms; Skin and Connective Tissue Diseases
C0153594 BXGD003669 Malignant neoplasm of testis Neoplasms; Male Urogenital Diseases; Endocrine System Diseases
C0153687 BXGD003683 Secondary malignant neoplasm of skin Neoplasms; Skin and Connective Tissue Diseases
C0153690 BXGD003684 Secondary malignant neoplasm of bone Pathological Conditions, Signs and Symptoms; Neoplasms; Musculoskeletal Diseases
C0154920 BXGD003755 Pigmentary iris degeneration Eye Diseases; Skin and Connective Tissue Diseases
C0155626 BXGD003806 Acute myocardial infarction Pathological Conditions, Signs and Symptoms; Cardiovascular Diseases
C0162674 BXGD003973 Chronic progressive external ophthalmoplegia Pathological Conditions, Signs and Symptoms; Nutritional and Metabolic Diseases; Eye Diseases; Musculoskeletal Diseases; Nervous System Diseases
C0162830 BXGD003987 Dermatitis, Phototoxic Skin and Connective Tissue Diseases
C0162835 BXGD003989 Hypopigmentation disorder Skin and Connective Tissue Diseases
C0178874 BXGD004037 Tumor Progression Pathological Conditions, Signs and Symptoms
C0206633 BXGD004198 Angiomyolipoma Neoplasms
C0206651 BXGD004215 Clear Cell Sarcoma of Soft Tissue Neoplasms
C0206710 BXGD004258 Basal Cell Neoplasm Neoplasms
C0206735 BXGD004280 Melanoma, Amelanotic Neoplasms
C0206737 BXGD004282 Nevus, Intradermal Neoplasms
C0220633 BXGD004303 Uveal melanoma Neoplasms; Eye Diseases
C0221436 BXGD004461 Melanoderma (disorder) Pathological Conditions, Signs and Symptoms; Skin and Connective Tissue Diseases
C0234632 BXGD004691 Reduced visual acuity Pathological Conditions, Signs and Symptoms; Eye Diseases; Nervous System Diseases
C0234985 BXGD004708 Mental deterioration Mental Disorders
C0236734 BXGD004823 Caffeine related disorders
C0239804 BXGD004995 White hair
C0241165 BXGD005083 Thick skin
C0242596 BXGD005181 Neoplasm, Residual Pathological Conditions, Signs and Symptoms; Neoplasms
C0242852 BXGD005197 Proliferative vitreoretinopathy Eye Diseases
C0242994 BXGD005205 Hantavirus Infections Infections
C0262977 BXGD005274 Achromia of skin Skin and Connective Tissue Diseases
C0268490 BXGD005962 Tyrosinemia, Type I Congenital, Hereditary, and Neonatal Diseases and Abnormalities; Nutritional and Metabolic Diseases; Nervous System Diseases
C0268494 BXGD005963 Oculocutaneous albinism type 1 Congenital, Hereditary, and Neonatal Diseases and Abnormalities; Nutritional and Metabolic Diseases; Eye Diseases; Skin and Connective Tissue Diseases
C0268495 BXGD005964 Oculocutaneous albinism type 2 Congenital, Hereditary, and Neonatal Diseases and Abnormalities; Nutritional and Metabolic Diseases; Eye Diseases; Skin and Connective Tissue Diseases
C0268500 BXGD005966 Yellow mutant oculocutaneous albinism Congenital, Hereditary, and Neonatal Diseases and Abnormalities; Nutritional and Metabolic Diseases; Eye Diseases; Skin and Connective Tissue Diseases
C0268503 BXGD005967 Autosomal recessive ocular albinism Congenital, Hereditary, and Neonatal Diseases and Abnormalities; Nutritional and Metabolic Diseases; Eye Diseases; Skin and Connective Tissue Diseases
C0271051 BXGD006153 Macular retinal edema Eye Diseases
C0271385 BXGD006193 Horizontal Nystagmus Eye Diseases; Nervous System Diseases
C0276640 BXGD006436 Transmissible mink encephalopathy Pathological Conditions, Signs and Symptoms; Infections; Nervous System Diseases
C0278592 BXGD006544 Adult Angiosarcoma Neoplasms
C0278880 BXGD006611 Stage I Cutaneous Melanoma AJCC v6
C0278881 BXGD006612 stage II melanoma
C0278882 BXGD006613 Stage III Cutaneous Melanoma AJCC v6
C0278883 BXGD006614 Metastatic melanoma Neoplasms
C0279988 BXGD006707 Childhood Angiosarcoma Neoplasms
C0280100 BXGD006713 Solid Neoplasm Neoplasms
C0311251 BXGD006870 Simple buphthalmos
C0333008 BXGD006916 Congenital hypopigmentation Skin and Connective Tissue Diseases
C0333516 BXGD006957 Tumor necrosis Pathological Conditions, Signs and Symptoms
C0334424 BXGD007064 Nodular melanoma Neoplasms; Skin and Connective Tissue Diseases
C0334439 BXGD007069 Malignant desmoplastic melanoma Neoplasms
C0337439 BXGD007160 Iron measurement
C0338656 BXGD007211 Impaired cognition Mental Disorders
C0339619 BXGD007274 Congenital esotropia Congenital, Hereditary, and Neonatal Diseases and Abnormalities; Eye Diseases; Nervous System Diseases
C0342257 BXGD007447 Complications of Diabetes Mellitus Endocrine System Diseases
C0342552 BXGD007505 Autoimmune endocrine disease Immune System Diseases; Endocrine System Diseases
C0342684 BXGD007525 Ocular albinism, type I Congenital, Hereditary, and Neonatal Diseases and Abnormalities; Nutritional and Metabolic Diseases; Eye Diseases; Skin and Connective Tissue Diseases
C0346053 BXGD007770 Atypical fibroxanthoma of skin Neoplasms
C0346977 BXGD007839 Secondary malignant neoplasm of spleen Neoplasms; Hemic and Lymphatic Diseases
C0349204 BXGD007892 Nonorganic psychosis Mental Disorders
C0349515 BXGD007913 Amelanotic Skin Melanoma Neoplasms; Skin and Connective Tissue Diseases
C0376358 BXGD007992 Malignant neoplasm of prostate Neoplasms; Male Urogenital Diseases
C0406208 BXGD008330 Suntan
C0428578 BXGD008634 Iron level result
C0456909 BXGD008883 Blindness Pathological Conditions, Signs and Symptoms; Eye Diseases; Nervous System Diseases
C0522214 BXGD009196 Abnormal visual evoked potential Nervous System Diseases
C0524851 BXGD009246 Neurodegenerative Disorders Nervous System Diseases
C0525045 BXGD009255 Mood Disorders Mental Disorders
C0549567 BXGD009387 Pigmentation Disorders Pathological Conditions, Signs and Symptoms; Skin and Connective Tissue Diseases
C0553723 BXGD009416 Squamous cell carcinoma of skin Neoplasms; Skin and Connective Tissue Diseases
C0555198 BXGD009432 Malignant Glioma Neoplasms
C0578626 BXGD009551 blue iris (physical finding)
C0595936 BXGD009628 Aqueous Humor Disorders Eye Diseases
C0596263 BXGD009639 Carcinogenesis Pathological Conditions, Signs and Symptoms; Neoplasms
C0600139 BXGD009695 Prostate carcinoma Neoplasms; Male Urogenital Diseases
C0600518 BXGD009711 Choroidal Neovascularization Pathological Conditions, Signs and Symptoms; Eye Diseases
C0677932 BXGD009736 Progressive Neoplastic Disease
C0677944 BXGD009738 Sentinel node (disorder)
C0678222 BXGD009749 Breast Carcinoma Neoplasms; Skin and Connective Tissue Diseases
C0686619 BXGD009835 Secondary malignant neoplasm of lymph node Pathological Conditions, Signs and Symptoms; Neoplasms
C0699790 BXGD009866 Colon Carcinoma Digestive System Diseases; Neoplasms
C0700095 BXGD009875 Central neuroblastoma Neoplasms; Nervous System Diseases
C0742343 BXGD010061 Acute Chest Syndrome Congenital, Hereditary, and Neonatal Diseases and Abnormalities; Respiratory Tract Diseases; Hemic and Lymphatic Diseases
C0751202 BXGD010347 Cystathionine beta-Synthase Deficiency Disease Congenital, Hereditary, and Neonatal Diseases and Abnormalities; Nutritional and Metabolic Diseases; Skin and Connective Tissue Diseases; Nervous System Diseases
C0751676 BXGD010549 Basal Cell Cancer Neoplasms
C0751781 BXGD010590 Dentatorubral-Pallidoluysian Atrophy Nervous System Diseases
C0860594 BXGD011234 Malignant melanoma, metastatic Neoplasms
C0870082 BXGD011309 Hyperkeratosis Pathological Conditions, Signs and Symptoms; Skin and Connective Tissue Diseases
C0877008 BXGD011325 Enzyme inhibition disorder
C0948089 BXGD011504 Acute Coronary Syndrome Cardiovascular Diseases
C1096063 BXGD011600 Drug Resistant Epilepsy Nervous System Diseases
C1096099 BXGD011602 Iris transillumination defect
C1260926 BXGD011844 Abnormal pigmentation
C1266184 BXGD011991 Atypical Teratoid Rhabdoid Tumor Neoplasms
C1269683 BXGD012001 Major Depressive Disorder Mental Disorders
C1269955 BXGD012005 Tumor Cell Invasion
C1285498 BXGD012171 Vegetation
C1298180 BXGD012246 Single tumor
C1304470 BXGD012339 Generalized vitiligo Skin and Connective Tissue Diseases
C1306459 BXGD012361 Primary malignant neoplasm Neoplasms
C1313983 BXGD012385 Acute contagious conjunctivitis Pathological Conditions, Signs and Symptoms; Infections; Eye Diseases
C1321872 BXGD012446 Stage IV Skin Melanoma Neoplasms; Skin and Connective Tissue Diseases
C1328931 BXGD012477 Multiple lentigines
C1332977 BXGD012569 Childhood Leukemia Neoplasms
C1368275 BXGD012897 Pigmented Basal Cell Carcinoma Neoplasms
C1377589 BXGD012923 Regressing nevus
C1456781 BXGD013123 Benign melanocytic nevus Neoplasms
C1519670 BXGD013241 Tumor Angiogenesis Pathological Conditions, Signs and Symptoms
C1519680 BXGD013244 Tumor Immunity Pathological Conditions, Signs and Symptoms
C1527390 BXGD013285 Neoplasms, Intracranial Neoplasms; Nervous System Diseases
C1533041 BXGD013307 Primary congenital glaucoma Congenital, Hereditary, and Neonatal Diseases and Abnormalities; Eye Diseases; Nervous System Diseases
C1568247 BXGD013418 Usher Syndrome, Type I Pathological Conditions, Signs and Symptoms; Congenital, Hereditary, and Neonatal Diseases and Abnormalities; Eye Diseases; Nervous System Diseases; Otorhinolaryngologic Diseases
C1621958 BXGD013468 Glioblastoma Multiforme Neoplasms
C1697878 BXGD013510 BK virus nephropathy Infections
C1704421 BXGD013558 Skin Pigmentation Disorder Pathological Conditions, Signs and Symptoms; Skin and Connective Tissue Diseases
C1840264 BXGD014439 IMMUNE SUPPRESSION
C1845069 BXGD014706 ALBINISM, OCULAR, WITH LATE-ONSET SENSORINEURAL DEAFNESS (disorder) Pathological Conditions, Signs and Symptoms; Congenital, Hereditary, and Neonatal Diseases and Abnormalities; Nutritional and Metabolic Diseases; Eye Diseases; Skin and Connective Tissue Diseases; Nervous System Diseases; Otorhinolaryngologic Diseases
C1847024 BXGD014850 ALBINISM, OCULOCUTANEOUS, TYPE IB (disorder) Congenital, Hereditary, and Neonatal Diseases and Abnormalities; Nutritional and Metabolic Diseases; Eye Diseases; Skin and Connective Tissue Diseases
C1847132 BXGD014853 ALBINISM, OCULOCUTANEOUS, TYPE I, TEMPERATURE-SENSITIVE Congenital, Hereditary, and Neonatal Diseases and Abnormalities; Nutritional and Metabolic Diseases; Eye Diseases; Skin and Connective Tissue Diseases
C1847835 BXGD014892 VITILIGO-ASSOCIATED MULTIPLE AUTOIMMUNE DISEASE SUSCEPTIBILITY 1 (finding) Skin and Connective Tissue Diseases
C1848606 BXGD014950 Vestibular hypofunction
C1848701 BXGD014967 Elevated hepatic transaminase
C1849221 BXGD015024 Fair hair
C1853141 BXGD015307 Slow decrease in visual acuity
C1862475 BXGD016132 Abnormality of retinal pigmentation
C1863198 BXGD016154 ALBINISM, OCULAR, WITH SENSORINEURAL DEAFNESS (disorder)
C1864172 BXGD016217 Peroxisome Biogenesis Disorder, Complementation Group G Congenital, Hereditary, and Neonatal Diseases and Abnormalities; Nutritional and Metabolic Diseases
C1876214 BXGD016567 ALBINOIDISM, OCULOCUTANEOUS, AUTOSOMAL DOMINANT Congenital, Hereditary, and Neonatal Diseases and Abnormalities; Nutritional and Metabolic Diseases; Eye Diseases; Skin and Connective Tissue Diseases
C1963184 BXGD016688 Nystagmus, CTCAE 3.0
C2314896 BXGD017019 Familial Atypical Mole Melanoma Syndrome Congenital, Hereditary, and Neonatal Diseases and Abnormalities; Neoplasms
C2347613 BXGD017039 Childhood Atypical Teratoid/Rhabdoid Tumor
C2673946 BXGD017234 Foveal hypoplasia (finding)
C2673954 BXGD017235 Absent skin pigmentation Skin and Connective Tissue Diseases
C2676026 BXGD017321 Optic nerve dysplasia
C2677190 BXGD017367 SKIN/HAIR/EYE PIGMENTATION, VARIATION IN, 3 (disorder)
C2931205 BXGD017977 Usher syndrome, type 1A Pathological Conditions, Signs and Symptoms; Congenital, Hereditary, and Neonatal Diseases and Abnormalities; Eye Diseases; Nervous System Diseases; Otorhinolaryngologic Diseases
C2931599 BXGD018039 Oculocutaneous albinism type 3 Congenital, Hereditary, and Neonatal Diseases and Abnormalities; Nutritional and Metabolic Diseases; Eye Diseases; Skin and Connective Tissue Diseases
C2931822 BXGD018068 Nasopharyngeal carcinoma Neoplasms; Stomatognathic Diseases; Otorhinolaryngologic Diseases
C2931875 BXGD018087 Albinism with hemorrhagic diathesis and pigmented reticuloendothelial cells Congenital, Hereditary, and Neonatal Diseases and Abnormalities; Nutritional and Metabolic Diseases; Eye Diseases; Skin and Connective Tissue Diseases; Hemic and Lymphatic Diseases
C2939419 BXGD018178 Secondary Neoplasm Pathological Conditions, Signs and Symptoms; Neoplasms
C3149136 BXGD018276 SKIN/HAIR/EYE PIGMENTATION 3, BLUE/GREEN EYES
C3152204 BXGD018462 MELANOMA, CUTANEOUS MALIGNANT, SUSCEPTIBILITY TO, 8
C3266262 BXGD018600 Multiple Chronic Conditions Pathological Conditions, Signs and Symptoms
C3266898 BXGD018606 Waardenburg Syndrome Congenital, Hereditary, and Neonatal Diseases and Abnormalities
C3278401 BXGD018739 Hypopigmentation of hair
C3539781 BXGD019086 Progressive cGVHD
C3665346 BXGD019278 Unspecified visual loss Pathological Conditions, Signs and Symptoms; Eye Diseases
C3665347 BXGD019279 Visual Impairment Pathological Conditions, Signs and Symptoms; Eye Diseases; Nervous System Diseases
C3665593 BXGD019294 Melanocytic nevus of skin Neoplasms
C3806221 BXGD019501 Giant melanosomes in melanocytes
C3811653 BXGD019662 Experimental Organism Basal Cell Carcinoma Neoplasms
C3854222 BXGD019826 Human immunodeficiency virus (HIV) II infection category B1
C3875321 BXGD019874 Inflammatory dermatosis Skin and Connective Tissue Diseases
C4021768 BXGD020766 Abnormality of metabolism/homeostasis
C4024172 BXGD021299 Abnormality of hair pigmentation
C4053528 BXGD021968 Cribriform Neuroepithelial Tumor Neoplasms
C4086165 BXGD022126 Childhood Neuroblastoma Neoplasms
C4316870 BXGD022707 Abnormality of the eye
C4520731 BXGD023036 Stage II Cutaneous Melanoma AJCC v6 and v7
C4520732 BXGD023037 Stage IV Cutaneous Melanoma AJCC v6 and v7
C4525234 BXGD023130 Xiphophorus Melanoma
C4551504 BXGD023324 Oculocutaneous albinism type 1A Congenital, Hereditary, and Neonatal Diseases and Abnormalities; Nutritional and Metabolic Diseases; Eye Diseases; Skin and Connective Tissue Diseases
C4553962 BXGD023553 Hyperkeratosis, CTCAE
C4554036 BXGD023557 Nystagmus, CTCAE 5.0
C4721806 BXGD023772 Carcinoma, Basal Cell Neoplasms
C4725091 BXGD023828 metastatic intraocular melanoma Neoplasms; Eye Diseases
C4725861 BXGD023840 Metastatic Malignant Neoplasm in the Viscera
C4732730 BXGD023895 Blood spots
Target protein-related  compounds
Compounds
BXGC Id Compound Name Strcuture Molecular Weight
BXGC0000190 Moupinamide 313.35
BXGC0000191 Tyramine 137.18
BXGC0000286 L-DOPA 197.19
BXGC0000340 Kaempferol 286.24
BXGC0000377 Glabrene 322.35
BXGC0000380 Glabrone 336.34
BXGC0000383 (S)-Naringenin 272.25
BXGC0000524 4-Methoxybenzaldehyde 136.15
BXGC0000530 Hydroquinone 110.11
BXGC0000603 Kanzonol W 336.34
BXGC0000605 Kanzonol U 308.33
BXGC0000681 Umbelliferone 162.14
BXGC0000764 L-Ascorbic acid 176.12
BXGC0001695 Artonol A 352.38
BXGC0001737 Norartocarpetin 286.24
BXGC0001767 (E)-Resveratrol 228.25
BXGC0001837 Quercetin 3-rutinoside 610.52
BXGC0001857 Caffeic acid 180.16
BXGC0001889 p-Coumaric acid 164.16
BXGC0002081 Artocarpin 436.5
BXGC0002748 Salicaldehyde 122.12
BXGC0003214 L-(-)-Phenylalanine 165.19
BXGC0003235 Linonin 470.52
BXGC0003478 2-Hydroxy-4-methoxybenzaldehyde 152.15
BXGC0003631 Phytosterol 414.72
BXGC0004552 Cuminaldehyde 148.21
BXGC0004556 1,2,3-Benzenetriol 126.11
BXGC0004559 1,3-Benzenediol 110.11
BXGC0004576 2-tert-Butyl-1,4-benzenediol 166.22
BXGC0004711 4-Hydroxybenzoic acid 138.12
BXGC0004797 (E)-2',4,4'-Trihydroxy-3-prenylchalcone 324.37
BXGC0004866 Nb-trans-Feruloylserotonin 352.38
BXGC0005084 N-cis-Caffeoyltyramine 299.32
BXGC0005086 N-Dihydroferuloyltyramine 315.36
BXGC0005186 (Z)-4',6-Dihydroxyaurone 254.24
BXGC0005683 Quercetin 302.24
BXGC0005867 Serotonin 176.22
BXGC0005871 Dopamine 153.18
BXGC0005894 Azelaic acid 188.22
BXGC0005911 Cyclokievitone 354.35
BXGC0005915 Formononetin 268.27
BXGC0005951 Parvisoflavone A 352.34
BXGC0006366 trans-Ferulic acid 194.18
BXGC0006635 Luteolin 286.24
BXGC0007028 beta-Thujaplicin 164.2
BXGC0007043 Phloroglucinol 126.11
BXGC0007629 Benzaldehyde 106.12
BXGC0008167 Chrysin 254.24
BXGC0008707 Isoliquiritigenin 256.25
BXGC0008753 Isoquercitrin 464.38
BXGC0008824 Astragalin 448.38
BXGC0010050 2',4',5,7-Tetrahydroxy-8-prenylisoflavone 354.35
BXGC0010053 Lupiwighteone 338.35
BXGC0011445 Artonin J 436.45
BXGC0012002 Glyinflanin H 308.33
BXGC0012178 Nb-Feruloyltryptamine 336.38
BXGC0012351 Kanzonol C 392.2
BXGC0013582 Curcumin 368.13
BXGC0014602 Kojic Acid 142.03
BXGC0014947 Glabridin 324.14
BXGC0015413 Shinpterocarpin 322.12
BXGC0015987 L-Mimosine 198.06
BXGC0016595 Kanzonol Y 410.21
BXGC0018149 Arbutin 272.09
BXGC0018882 Liquirtigenin 256.07
BXGC0019273 Glabrol 392.2
BXGC0019992 feruloylphenethylamine 297.14
BXGC0021779 N-Formylanonaine 293.11
BXGC0022526 LICOAGROCARPIN 338.15
BXGC0023925 Amurensin 534.17
BXGC0024132 1H-Indol-5-Ol 133.05
BXGC0024598 3,4-Didehydroglabridin 322.12
BXGC0026664 Gnetucleistol D 258.09
BXGC0029310 Abyssinone Ii 324.14
BXGC0029810 1,5-Bis(4-Hydroxy-3-Methoxyphenyl)-1,4-Pentadien-3-One 326.12
BXGC0029943 Phaseolin 322.12
BXGC0030396 Gamma-Thujaplicin 164.08
BXGC0031244 Kanzonol B 322.12
BXGC0031533 abyssinone I 322.12
BXGC0031628 (E)-1-[2,4-Dihydroxy-3-(3-Methylbut-2-Enyl)Phenyl]-3-(8-Hydroxy-2,2-Dimethylchromen-6-Yl)Prop-2-En-1-One 406.18
BXGC0031726 Licoagrochacone A 338.15
BXGC0032555 Hispaglabridin A 392.2
BXGC0032805 Derrone 336.1
BXGC0032936 Echinatin 270.09
BXGC0033761 3'-Hydroxy-4'-O-methylglabridin 354.15
BXGC0033917 Homobutein 286.08
BXGC0034074 Acrovestone 554.29
BXGC0035832 Dihydro-N-Caffeoyltyramine 301.13
BXGC0036864 Cyclovalone 366.15
BXGC0037565 Alpha-Thujaplicin 164.08
BXGC0037892 Caffeic Acid Phenethyl Amide 283.12
BXGC0037981 houttuynamide A 273.1
BXGC0039172 Oxyresveratrol 244.07
BXGC0039534 Orcinol 124.05
BXGC0040952 Dihydroresveratrol 230.09
BXGC0043398 Glyasperin D 370.18
BXGC0043577 shinflavanone 390.18
BXGC0044002 Bryoamaride 678.36
BXGC0044098 Lupenone 424.37
BXGC0047393 Glyasperin C 356.16
BXGC0047824 Kanzonol Z 406.18
BXGC0048117 Xambioona 388.17
BXGC0048343 Paratocarpin B 390.18
BXGC0049047 Epirhododendrin 328.15
BXGC0049349 4'-O-Methylglabridin 338.15
BXGC0049929 Isobavachalcone 324.14
BXGC0050658 Kanzonol X 394.21
BXGC0050676 Hispaglabridin B 390.18
BXGC0050724 2-(3,4-Dihydroxyphenyl)-5-Hydroxy-7-[(2R,3R,4S,5S,6R)-3,4,5-Trihydroxy-6-(Hydroxymethyl)Oxan-2-Yl]Oxychromen-4-One 448.1
BXGC0051077 4-Ethylresorcinol 138.07
The  target protein-related  foods
Foods
BXGF Id Food Name Scientific Name Food Group Number of compound? Number of compound in food, higher numbers indicate the food are more associated with the protein