acompound

General Compound Information
BXGC Id	BXGC0005511
Compound Name	D-Glucitol
Structure
Formula	C6H14O6
InchiKey	FBPFZTCFMRRESA-JGWLITMVSA-N
SMILES	OC[C@H](O)[C@@H](O)[C@H](O)[C@H](O)CO
Inchi	InChI=1S/C6H14O6/c7-1-3(9)5(11)6(12)4(10)2-8/h3-12H,1-2H2/t3-,4+,5-,6-/m1/s1
IUPAC	(2R,3R,4R,5S)-hexane-1,2,3,4,5,6-hexol
Molecular Weight	182.17
Pubchem Id	5780
Chembl Id	CHEMBL1682

Targets of Information Source

DrugBank

n.a

Uniport Id	BXGT Id	Protein Name	Status	Protein Class	Gene	Groups	Target Type
Uniport Id	BXGT Id	Protein Name	Status	Protein Class	Gene	Groups	Target Type

PDB

Uniport Id	BXGT Id	Protein Name	Status	Protein Class	Gene	Ki nM	ic50 nM	Kd nM	Ka M-1
Uniport Id	BXGT Id	Protein Name	Status	Protein Class	Gene	Ki nM	ic50 nM	Kd nM	Ka M-1
P37330	BXGT009978	Malate synthase G	reviewed	glcB	-	-	-	-	-
P0AEX9	BXGT007333	Maltose/maltodextrin-binding periplasmic protein	reviewed	malE	-	-	-	-	-
P24300	BXGT008961	Xylose isomerase	reviewed	xylA	-	-	-	-	-
P24627	BXGT008981	Lactotransferrin	reviewed	LTF	-	-	-	-	-
Q9ZBU1	BXGT022441	Probable xylitol oxidase	reviewed	xyoA	-	-	-	-	-
P12851	BXGT007853	Xylose isomerase	reviewed	xylA	-	-	-	-	-
P12070	BXGT007770	Xylose isomerase	reviewed	xylA	-	-	-	-	-
Q9A8X3	BXGT020044	Glucose-fructose oxidoreductase	unreviewed	CC_1225	-	-	-	-	-
Q89FN7	BXGT017742	Ribitol 2-dehydrogenase	unreviewed	rdh	-	-	-	-	-
A0A0R6L508	BXGT000608	Probable phosphatidylethanolamine transferase Mcr-1	reviewed	mcr1	-	-	-	-	-
A4FNP6	BXGT023203	Beta-glucosidase	unreviewed	celD	-	-	-	-	-
Q9P8C9	BXGT021315	Xylose isomerase	unreviewed	xylA	-	-	-	-	-
P20807	BXGT008601	Calpain-3	reviewed	CAPN3	Enzyme	-	-	-	-
P17931	BXGT008356	Galectin-3	reviewed	LGALS3	Signaling	-	-	-	-
Q92N06	BXGT025209	Probable sorbitol dehydrogenase	unreviewed	smoS	-	-	-	-	-

Binding DB

n.a

Uniport Id	BXGT Id	Protein Name	Status	Protein Class	Gene	Ki nM	ic50 nM	Kd nM	EC50 nM
Uniport Id	BXGT Id	Protein Name	Status	Protein Class	Gene	Ki nM	ic50 nM	Kd nM	EC50 nM

CHEMBL

Uniport Id	BXGT Id	Protein Name	Status	Protein Class	Gene	width="10%">Type	Relation	value	Units
Uniport Id	BXGT Id	Protein Name	Status	Protein Class	Gene	Type	Relation	value	Units
P10323	BXGT007557	Acrosin	reviewed	Enzyme	ACR	Inhibition	'='	38	%
P83916	BXGT012025	Chromobox protein homolog 1	reviewed	Epigenetic regulator	CBX1	Potency	-	2818	nM
P39748	BXGT010134	Flap endonuclease 1	reviewed	Enzyme	FEN1	Potency	-	89125	nM
P27695	BXGT009199	DNA-(apurinic or apyrimidinic site) lyase	reviewed	-	APEX1	Potency	-	23778	nM
O75496	BXGT005132	Geminin	reviewed	-	GMNN	Potency	-	103	nM

Foods containing the compound

Foods

BXGF Id	Food Name	Scientific Name	Food Group
BXGF Id	Food Name	Scientific Name	Food Group
BXGF00027	Chinese mustard	Brassica juncea	Vegetables
BXGF00043	Caraway	Carum carvi	Herbs and Spices
BXGF00076	Loquat	Eriobotrya japonica	Fruits
BXGF00105	Apple	Malus pumila	Fruits
BXGF00135	Date	Phoenix dactylifera	Fruits
BXGF00144	Apricot	Prunus armeniaca	Fruits
BXGF00146	Sour cherry	Prunus cerasus	Fruits
BXGF00151	Pomegranate	Punica granatum	Fruits
BXGF00162	Red raspberry	Rubus idaeus	Fruits
BXGF00176	Rowanberry	Sorbus aucuparia	Fruits
BXGF00310	Coconut	Cocos nucifera	Fruits
BXGF00808	Pomes		Fruits
BXGF00823	Fruits		Fruits
BXGF01084	Duranta erecta	Duranta erecta	Medicinal Plant
BXGF01890	Trollius chinensis	Trollius chinensis	Medicinal Plant
BXGF02509	Xanthium sibiricum	Xanthium sibiricum	Medicinal Plant
BXGF03100	Astragalus complanatus	Astragalus complanatus	Medicinal Plant
BXGF03158	Rheum officinale	Rheum officinale	Medicinal Plant
BXGF03919	Xanthium strumarium	Xanthium strumarium	Medicinal Plant
BXGF03988	Rheum coreanum	Rheum coreanum	Others
BXGF04539	Rheum palmatum	Rheum palmatum	Medicinal Plant
BXGF04889	Pogostemon cablin	Pogostemon cablin	Medicinal Plant
BXGF05877	Rheum tanguticum	Rheum tanguticum	Medicinal Plant

The compound-realted diseases

Diseases

BXGD Id	Disease Name	CUI Disease Id	Disease Class Name	Number of targets^{?Number of targets related to compound connecting disease, higher numbers indicate the compound is more associated with the disease}