acompound

Showing entry for beta-Mangostin

　　　　　　　　　　　　　　　

General Compound Information
BXGC Id	BXGC0008149
Compound Name	beta-Mangostin
Structure
Formula	C25H28O6
InchiKey	YRKKJHJIWCRNCW-UHFFFAOYSA-N
SMILES	COC1=CC2=C(C(O)=C1CC=C(C)C)C(=O)C1=C(CC=C(C)C)C(OC)=C(O)C=C1O2
Inchi	InChI=1S/C25H28O6/c1-13(2)7-9-15-18(29-5)12-20-22(23(15)27)24(28)21-16(10-8-14(3)4)25(30-6)17(26)11-19(21)31-20/h7-8,11-12,26-27H,9-10H2,1-6H3
IUPAC	1,6-dihydroxy-3,7-dimethoxy-2,8-bis(3-methylbut-2-en-1-yl)-9H-xanthen-9-one
Molecular Weight	424.49
Pubchem Id	5495925
Chembl Id	CHEMBL261706

Targets of Information Source

DrugBank

n.a

Uniport Id	BXGT Id	Protein Name	Status	Protein Class	Gene	Groups	Target Type
Uniport Id	BXGT Id	Protein Name	Status	Protein Class	Gene	Groups	Target Type

PDB

n.a

Uniport Id	BXGT Id	Protein Name	Status	Protein Class	Gene	Ki nM	ic50 nM	Kd nM	Ka M-1
Uniport Id	BXGT Id	Protein Name	Status	Protein Class	Gene	Ki nM	ic50 nM	Kd nM	Ka M-1

Binding DB

Uniport Id	BXGT Id	Protein Name	Status	Protein Class	Gene	Ki nM	ic50 nM	Kd nM	EC50 nM
Uniport Id	BXGT Id	Protein Name	Status	Protein Class	Gene	Ki nM	ic50 nM	Kd nM	EC50 nM
reviewed	BXGT010694	Fatty acid synthase	reviewed	Enzyme	FASN	-	24830	-	-
reviewed	BXGT005157	Isocitrate dehydrogenase [NADP] cytoplasmic	reviewed		IDH1	12000	-	-	-
reviewed	BXGT008526	Nuclear factor NF-kappa-B p105 subunit	reviewed	Transcription factor	NFKB1	-	7500	-	-
reviewed	BXGT012754	Transcription factor p65	reviewed	Transcription factor	RELA	-	12100	-	-
reviewed	BXGT007573	Sialidase	reviewed		nanH	-	60700	-	-
reviewed	BXGT007573	Sialidase	reviewed		nanH	24900	-	-	-

CHEMBL

Uniport Id	BXGT Id	Protein Name	Status	Protein Class	Gene	width="10%">Type	Relation	value	Units
Uniport Id	BXGT Id	Protein Name	Status	Protein Class	Gene	Type	Relation	value	Units
Q64725	BXGT016130	Tyrosine-protein kinase SYK	reviewed	-	Syk	Activity	-	-	-
P10481	BXGT007573	Sialidase	reviewed	-	nanH	Ki	'='	24900	nM
Q04206	BXGT012754	Transcription factor p65	reviewed	Transcription factor	RELA	IC50	'='	12100	nM
P10481	BXGT007573	Sialidase	reviewed	-	nanH	IC50	'='	60700	nM
Q07014	BXGT012913	Tyrosine-protein kinase Lyn	reviewed	-	Lyn	Activity	-	-	-
O75874	BXGT005157	Isocitrate dehydrogenase [NADP] cytoplasmic	reviewed	-	IDH1	Ki	'='	12000	nM
P19838	BXGT008526	Nuclear factor NF-kappa-B p105 subunit	reviewed	Transcription factor	NFKB1	IC50	'='	7500	nM
P49327	BXGT010694	Fatty acid synthase	reviewed	Enzyme	FASN	IC50	'='	24830	nM

Foods containing the compound

Foods

BXGF Id	Food Name	Scientific Name	Food Group
BXGF Id	Food Name	Scientific Name	Food Group
BXGF00373	Purple mangosteen	Garcinia mangostana	Fruits
BXGF00823	Fruits		Fruits
BXGF00848	Mundu	Garcinia dulcis	Fruits
BXGF00864	Nicotiana sylvestris	Nicotiana sylvestris	Others
BXGF00927	Dolomiaea souliei	Dolomiaea souliei	Others
BXGF01007	Eucalyptus camaldulensis	Eucalyptus camaldulensis	Medicinal Plant
BXGF03915	Cratoxylum cochinchinense	Cratoxylum cochinchinense	Medicinal Plant
BXGF03981	Senecio vellereus	Senecio vellereus	Others
BXGF04031	Garcinia cowa	Garcinia cowa	Medicinal Plant
BXGF04519	Serpocaulon triseriale	Serpocaulon triseriale	Others
BXGF05090	Lonicera hypoleuca	Lonicera hypoleuca	Human Edible Plant
BXGF05213	Halimodendron halodendron	Halimodendron halodendron	Others
BXGF06008	Aster bellidiastrum	Aster bellidiastrum	Others
BXGF06276	Wibelia divaricata	Wibelia divaricata	Others

The compound-realted diseases

Diseases

BXGD Id	Disease Name	CUI Disease Id	Disease Class Name	Number of targets^{?Number of targets related to compound connecting disease, higher numbers indicate the compound is more associated with the disease}