acompound

Showing entry for 3,4-Dihydro-2H-1-benzopyran-2-one

General Compound Information
BXGC Id	BXGC0008174
Compound Name	3,4-Dihydro-2H-1-benzopyran-2-one
Structure
Formula	C9H8O2
InchiKey	VMUXSMXIQBNMGZ-UHFFFAOYSA-N
SMILES	O=C1CCC2=CC=CC=C2O1
Inchi	InChI=1S/C9H8O2/c10-9-6-5-7-3-1-2-4-8(7)11-9/h1-4H,5-6H2
IUPAC	3,4-dihydro-2H-1-benzopyran-2-one
Molecular Weight	148.16
Pubchem Id	660
Chembl Id	CHEMBL89306

Targets of Information Source

DrugBank

n.a

Uniport Id	BXGT Id	Protein Name	Status	Protein Class	Gene	Groups	Target Type
Uniport Id	BXGT Id	Protein Name	Status	Protein Class	Gene	Groups	Target Type

PDB

n.a

Uniport Id	BXGT Id	Protein Name	Status	Protein Class	Gene	Ki nM	ic50 nM	Kd nM	Ka M-1
Uniport Id	BXGT Id	Protein Name	Status	Protein Class	Gene	Ki nM	ic50 nM	Kd nM	Ka M-1

Binding DB

50146070

Uniport Id	BXGT Id	Protein Name	Status	Protein Class	Gene	Ki nM	ic50 nM	Kd nM	EC50 nM
Uniport Id	BXGT Id	Protein Name	Status	Protein Class	Gene	Ki nM	ic50 nM	Kd nM	EC50 nM
reviewed	BXGT006474	NAD-dependent histone deacetylase SIR2	reviewed		SIR2	-	122000	-	-

CHEMBL

CHEMBL89306

Uniport Id	BXGT Id	Protein Name	Status	Protein Class	Gene	width="10%">Type	Relation	value	Units
Uniport Id	BXGT Id	Protein Name	Status	Protein Class	Gene	Type	Relation	value	Units
P06700	BXGT006474	NAD-dependent histone deacetylase SIR2	reviewed	-	SIR2	Inhibition	'='	0	uM
P83916	BXGT012025	Chromobox protein homolog 1	reviewed	Epigenetic regulator	CBX1	Potency	-	100000	nM
P63092	BXGT011495	Guanine nucleotide-binding protein G(s) subunit alpha isoforms short	reviewed	-	GNAS	Potency	-	5623	nM
P06700	BXGT006474	NAD-dependent histone deacetylase SIR2	reviewed	-	SIR2	MGC	'='	0	uM
P06700	BXGT006474	NAD-dependent histone deacetylase SIR2	reviewed	-	SIR2	IC50	'='	122000	nM
P27169	BXGT009161	Serum paraoxonase/arylesterase 1	reviewed	-	PON1	Activity	'='	12	umol/min/mg
P06700	BXGT006474	NAD-dependent histone deacetylase SIR2	reviewed	-	SIR2	SI	'='	144	-
Q16236	BXGT013624	Nuclear factor erythroid 2-related factor 2	reviewed	Enzyme	NFE2L2	Potency	-	74978	nM

Foods containing the compound

Foods

BXGF Id	Food Name	Scientific Name	Food Group
BXGF Id	Food Name	Scientific Name	Food Group
BXGF00019	Tarragon	Artemisia dracunculus	Herbs and Spices
BXGF00146	Sour cherry	Prunus cerasus	Fruits
BXGF00819	Pulses		Pulses
BXGF00824	Green vegetables		Vegetables
BXGF01254	Petrorhagia dubia	Petrorhagia dubia	Others
BXGF01678	Nepeta multifida	Nepeta multifida	Others
BXGF01702	Eremostachys moluccelloides	Eremostachys moluccelloides	Others
BXGF02654	Guarea trichilioides	Guarea trichilioides	Others
BXGF02960	Vicia benghalensis	Vicia benghalensis	Agricultural Plant
BXGF02962	Melilotus officinalis	Melilotus officinalis	Medicinal Plant
BXGF03070	Callerya cinerea	Callerya cinerea	Human Edible Plant
BXGF03646	Carlina acanthifolia	Carlina acanthifolia	Medicinal Plant
BXGF03810	Osmanthus heterophyllus	Osmanthus heterophyllus	Others
BXGF04081	Maytenus hookeri	Maytenus hookeri	Medicinal Plant
BXGF04088	Aster ageratoides	Aster ageratoides	Human Edible Plant
BXGF04108	Delphinium cashmerianum	Delphinium cashmerianum	Medicinal Plant
BXGF04118	Thaminophyllum multiflorum	Thaminophyllum multiflorum	Others
BXGF04127	Tephrosia pumila	Tephrosia pumila	Medicinal Plant
BXGF04137	Senecio rupestris	Senecio rupestris	Others
BXGF04143	Vitis silvestris	Vitis silvestris	Others
BXGF04148	Pluchea suaveolens	Pluchea suaveolens	Others
BXGF04152	Mussaenda parviflora	Mussaenda parviflora	Others
BXGF04160	Pilocarpus spicatus	Pilocarpus spicatus	Others
BXGF04166	Walsura tubulata	Walsura tubulata	Others
BXGF04169	Anisodus tanguticus	Anisodus tanguticus	Medicinal Plant
BXGF04183	Tephrosia vogelii	Tephrosia vogelii	Medicinal Plant
BXGF04195	Panax papyrifer	Panax papyrifer	Others
BXGF04218	Heuchera cylindrica	Heuchera cylindrica	Medicinal Plant
BXGF04223	Amelanchier vulgaris	Amelanchier vulgaris	Others
BXGF04242	Prunus lusitanica	Prunus lusitanica	Medicinal Plant
BXGF04291	Calea pilosa	Calea pilosa	Others
BXGF04307	Stevia connata	Stevia connata	Others
BXGF04330	Helichrysum davenportii	Helichrysum davenportii	Others
BXGF04335	Plectranthus purpuratus	Plectranthus purpuratus	Others
BXGF04344	Cineraria geifolia	Cineraria geifolia	Others
BXGF04353	Halocarpus biformis	Halocarpus biformis	Others
BXGF04397	Iochroma australe	Iochroma australe	Others
BXGF04798	Ranunculus acris	Ranunculus acris	Medicinal Plant
BXGF05069	Piper sanctum	Piper sanctum	Human Edible Plant

The compound-realted diseases

Diseases

BXGD Id	Disease Name	CUI Disease Id	Disease Class Name	Number of targets^{?Number of targets related to compound connecting disease, higher numbers indicate the compound is more associated with the disease}