acompound

Showing entry for Cirsilineol

General Compound Information
BXGC Id	BXGC0008972
Compound Name	Cirsilineol
Structure
Formula	C18H16O7
InchiKey	VKOSQMWSWLZQPA-UHFFFAOYSA-N
SMILES	COC1=CC2=C(C(=O)C=C(O2)C2=CC(OC)=C(O)C=C2)C(O)=C1OC
Inchi	InChI=1S/C18H16O7/c1-22-13-6-9(4-5-10(13)19)12-7-11(20)16-14(25-12)8-15(23-2)18(24-3)17(16)21/h4-8,19,21H,1-3H3
IUPAC	5-hydroxy-2-(4-hydroxy-3-methoxyphenyl)-6,7-dimethoxy-4H-chromen-4-one
Molecular Weight	344.32
Pubchem Id	162464
Chembl Id	CHEMBL487213

Targets of Information Source

DrugBank

n.a

Uniport Id	BXGT Id	Protein Name	Status	Protein Class	Gene	Groups	Target Type
Uniport Id	BXGT Id	Protein Name	Status	Protein Class	Gene	Groups	Target Type

PDB

n.a

Uniport Id	BXGT Id	Protein Name	Status	Protein Class	Gene	Ki nM	ic50 nM	Kd nM	Ka M-1
Uniport Id	BXGT Id	Protein Name	Status	Protein Class	Gene	Ki nM	ic50 nM	Kd nM	Ka M-1

Binding DB

50412272

Uniport Id	BXGT Id	Protein Name	Status	Protein Class	Gene	Ki nM	ic50 nM	Kd nM	EC50 nM
Uniport Id	BXGT Id	Protein Name	Status	Protein Class	Gene	Ki nM	ic50 nM	Kd nM	EC50 nM
reviewed	BXGT006700	Aldo-keto reductase family 1 member B1	reviewed		Akr1b1	-	6760.83	-	-

CHEMBL

CHEMBL487213

Uniport Id	BXGT Id	Protein Name	Status	Protein Class	Gene	width="10%">Type	Relation	value	Units
Uniport Id	BXGT Id	Protein Name	Status	Protein Class	Gene	Type	Relation	value	Units
P07943	BXGT006700	Aldo-keto reductase family 1 member B1	reviewed	-	Akr1b1	IC50	'='	6760	nM
P80457	BXGT011911	Xanthine dehydrogenase/oxidase	reviewed	-	XDH	Inhibition	'='	1	%

Foods containing the compound

Foods

BXGF Id	Food Name	Scientific Name	Food Group
BXGF Id	Food Name	Scientific Name	Food Group
BXGF00010	Lemon verbena	Aloysia triphylla	Herbs and Spices
BXGF00019	Tarragon	Artemisia dracunculus	Herbs and Spices
BXGF00056	Mandarin orange (Clementine, Tangerine)	Citrus reticulata	Fruits
BXGF00089	Hyssop	Hyssopus officinalis	Herbs and Spices
BXGF00165	Common sage	Salvia officinalis	Herbs and Spices
BXGF00183	Common thyme	Thymus vulgaris	Herbs and Spices
BXGF00948	Artemisia apiacea	Artemisia apiacea	Medicinal Plant
BXGF01065	Artemisia capillaris	Artemisia capillaris	Medicinal Plant
BXGF01138	Tulipa sylvestris	Tulipa sylvestris	Human Edible Plant
BXGF01506	Thymus quinquecostatus	Thymus quinquecostatus	Medicinal Plant
BXGF01748	Dacryodes normandii	Dacryodes normandii	Others
BXGF01790	Riccia fluitans	Riccia fluitans	Others
BXGF01800	Salvia palaestina	Salvia palaestina	Others
BXGF01966	Chromolaena odorata	Chromolaena odorata	Medicinal Plant
BXGF02592	Ilex affinis	Ilex affinis	Human Edible Plant
BXGF02667	Anaxagorea clavata	Anaxagorea clavata	Others
BXGF02811	Cyperus haspan	Cyperus haspan	Human Edible Plant
BXGF03144	Stenostomum lucidum	Stenostomum lucidum	Others
BXGF03147	Beyeria brevifolia	Beyeria brevifolia	Others
BXGF03421	Kaempferia pulchra	Kaempferia pulchra	Medicinal Plant
BXGF03534	Drosera peltata	Drosera peltata	Medicinal Plant
BXGF03712	Arnica nevadensis	Arnica nevadensis	Others
BXGF03745	Odixia angusta	Odixia angusta	Others
BXGF03760	Prunus laurocerasus	Prunus laurocerasus	Medicinal Plant
BXGF03812	Ficus formosana	Ficus formosana	Human Edible Plant
BXGF03843	Dipterocarpus alatus	Dipterocarpus alatus	Medicinal Plant
BXGF03864	Echinops amplexicaulis	Echinops amplexicaulis	Medicinal Plant
BXGF03873	Quercus aegilops	Quercus aegilops	Medicinal Plant
BXGF03883	Chloranthus tianmushanensis	Chloranthus tianmushanensis	Others
BXGF03897	Prosopis glandulosa	Prosopis glandulosa	Human Edible Plant
BXGF03916	Aria pallescens	Aria pallescens	Others
BXGF03926	Simira eliezeriana	Simira eliezeriana	Others
BXGF03939	Senecio squalidus	Senecio squalidus	Medicinal Plant
BXGF03951	Araujia sericifera	Araujia sericifera	Medicinal Plant
BXGF03966	Artemisia monogyna	Artemisia monogyna	Others
BXGF03986	Epaltes gariepina	Epaltes gariepina	Others
BXGF03991	Seriphidium cinum	Seriphidium cinum	Medicinal Plant
BXGF04002	Dendrosenecio kilimanjari	Dendrosenecio kilimanjari	Others
BXGF04009	Isodon kameba	Isodon kameba	Medicinal Plant
BXGF04016	Pterocarpus grandiflorus	Pterocarpus grandiflorus	Others
BXGF04030	Chromolaena pulchella	Chromolaena pulchella	Others
BXGF04041	Bursaria spinosa	Bursaria spinosa	Human Edible Plant
BXGF04054	Taxodium mucronatum	Taxodium mucronatum	Medicinal Plant
BXGF04066	Gardenia fosbergii	Gardenia fosbergii	Others
BXGF04073	Vitex madiensis	Vitex madiensis	Medicinal Plant
BXGF04144	Agnorhiza bolanderi	Agnorhiza bolanderi	Others
BXGF04271	Artemisia annua	Artemisia annua	Medicinal Plant
BXGF04385	Vatica cinerea	Vatica cinerea	Others
BXGF04708	Sesbania punicea	Sesbania punicea	Others
BXGF05011	Artemisia capillaries	Artemisia capillaries	Others
BXGF05261	Artemisia chinensis	Artemisia chinensis	Medicinal Plant
BXGF05281	Fritillaria thunbergii	Fritillaria thunbergii	Medicinal Plant
BXGF05324	Goniothalamus thwaitesii	Goniothalamus thwaitesii	Others
BXGF05355	Plectranthus sylvestris	Plectranthus sylvestris	Medicinal Plant
BXGF05376	Eschscholzia californica	Eschscholzia californica	Medicinal Plant
BXGF05460	Bryum weigelii	Bryum weigelii	Others
BXGF05534	Walsura chrysogyne	Walsura chrysogyne	Others
BXGF05639	Mulguraea tridens	Mulguraea tridens	Others
BXGF05704	Securidaca inappendiculata	Securidaca inappendiculata	Medicinal Plant
BXGF05843	Pteris prolifera	Pteris prolifera	Others
BXGF06038	Eupatorium lindleyanum	Eupatorium lindleyanum	Medicinal Plant
BXGF06184	Plantago cornuti	Plantago cornuti	Medicinal Plant
BXGF06288	Salvinia imbricata	Salvinia imbricata	Others

The compound-realted diseases

Diseases

BXGD Id	Disease Name	CUI Disease Id	Disease Class Name	Number of targets^{?Number of targets related to compound connecting disease, higher numbers indicate the compound is more associated with the disease}