acompound

Showing entry for Goniothalamin

　　　　　　　　　　　　　　　

General Compound Information
BXGC Id	BXGC0016149
Compound Name	Goniothalamin
Structure
Formula	C13H12O2
InchiKey	RLGHFVLWYYVMQZ-BZYZDCJZSA-N
SMILES	O=C1C=CC[C@@H](O1)/C=C/c1ccccc1
Inchi	InChI=1S/C13H12O2/c14-13-8-4-7-12(15-13)10-9-11-5-2-1-3-6-11/h1-6,8-10,12H,7H2/b10-9+/t12-/m1/s1
IUPAC	(2R)-2-[(E)-2-phenylethenyl]-2,3-dihydropyran-6-one
Molecular Weight	200.08
Pubchem Id	6440856
Chembl Id	CHEMBL464443

Targets of Information Source

DrugBank

n.a

Uniport Id	BXGT Id	Protein Name	Status	Protein Class	Gene	Groups	Target Type
Uniport Id	BXGT Id	Protein Name	Status	Protein Class	Gene	Groups	Target Type

PDB

n.a

Uniport Id	BXGT Id	Protein Name	Status	Protein Class	Gene	Ki nM	ic50 nM	Kd nM	Ka M-1
Uniport Id	BXGT Id	Protein Name	Status	Protein Class	Gene	Ki nM	ic50 nM	Kd nM	Ka M-1

Binding DB

n.a

Uniport Id	BXGT Id	Protein Name	Status	Protein Class	Gene	Ki nM	ic50 nM	Kd nM	EC50 nM
Uniport Id	BXGT Id	Protein Name	Status	Protein Class	Gene	Ki nM	ic50 nM	Kd nM	EC50 nM

CHEMBL

Uniport Id	BXGT Id	Protein Name	Status	Protein Class	Gene	width="10%">Type	Relation	value	Units
Uniport Id	BXGT Id	Protein Name	Status	Protein Class	Gene	Type	Relation	value	Units
Q04206	BXGT012754	Transcription factor p65	reviewed	Transcription factor	RELA	IC50	'='	7000	nM
P19838	BXGT008526	Nuclear factor NF-kappa-B p105 subunit	reviewed	Transcription factor	NFKB1	IC50	'='	7000	nM
Q00653	BXGT012541	Nuclear factor NF-kappa-B p100 subunit	reviewed	Transcription factor	NFKB2	IC50	'='	7000	nM
P30530	BXGT009431	Tyrosine-protein kinase receptor UFO	reviewed	Kinase	AXL	Activity	-	-	-
O14980	BXGT004119	Exportin-1	reviewed	Receptor	XPO1	Inhibition	'='	50	%
O14980	BXGT004119	Exportin-1	reviewed	Receptor	XPO1	Inhibition	-	-	-
O14980	BXGT004119	Exportin-1	reviewed	Receptor	XPO1	Inhibition	'='	0	%
O14980	BXGT004119	Exportin-1	reviewed	Receptor	XPO1	Inhibition	'='	100	%

Foods containing the compound

Foods

BXGF Id	Food Name	Scientific Name	Food Group
BXGF Id	Food Name	Scientific Name	Food Group
BXGF00950	Aconitum vilmorini	Aconitum vilmorini	Others
BXGF03058	Gymnacranthera paniculata	Gymnacranthera paniculata	Others
BXGF03257	Anagallis monelli	Anagallis monelli	Medicinal Plant
BXGF04109	Saussurea costus	Saussurea costus	Medicinal Plant
BXGF04500	Eliokarmos thyrsoides	Eliokarmos thyrsoides	Others
BXGF05084	Goniothalamus leiocarpus	Goniothalamus leiocarpus	Others
BXGF06283	Mortonia palmeri	Mortonia palmeri	Others

The compound-realted diseases

Diseases

BXGD Id	Disease Name	CUI Disease Id	Disease Class Name	Number of targets^{?Number of targets related to compound connecting disease, higher numbers indicate the compound is more associated with the disease}