Showing entry for Nuclear factor NF-kappa-B p100 subunit


　 　 　 　 　 　 　 　 　 　 　 　
General Target Information
BXGT IdBXGT012541
Protein NameNuclear factor NF-kappa-B p100 subunit
Uniport IdQ00653
GeneNFKB2
Gene Id4791
DomainAnk; Death; RHD_dimer; RHD_DNA_bind
Pfam PF12796   PF00531   PF16179   PF00554  
OrganismHomo sapiens (Human)
Target protein  affiliated  biological  pathways
KEGG
Class Subclass KEGG Id Pathway Name
3. Environmental Information Processing 3.2 Signal transduction hsa04010 MAPK signaling pathway
3. Environmental Information Processing 3.2 Signal transduction hsa04064 NF-kappa B signaling pathway
5. Organismal Systems 5.8 Development hsa04380 Osteoclast differentiation
5. Organismal Systems 5.1 Immune system hsa04625 C-type lectin receptor signaling pathway
6. Human Diseases 6.8 Infectious diseases: Bacterial hsa05134 Legionellosis
6. Human Diseases 6.9 Infectious diseases: Viral hsa05166 Human T-cell leukemia virus 1 infection
6. Human Diseases 6.9 Infectious diseases: Viral hsa05169 Epstein-Barr virus infection
6. Human Diseases 6.1 Cancers: Overview hsa05200 Pathways in cancer
6. Human Diseases 6.1 Cancers: Overview hsa05203 Viral carcinogenesis
6. Human Diseases 6.2 Cancers: Specific types hsa05224 Breast cancer
Gene Ontology
GO Type GO Id Gene Ontology
Biological Process GO:0007568 aging
Biological Process GO:0030198 extracellular matrix organization
Biological Process GO:0002268 follicular dendritic cell differentiation
Biological Process GO:0002467 germinal center formation
Biological Process GO:0038061 NIK/NF-kappaB signaling
Biological Process GO:0051092 positive regulation of NF-kappaB transcription factor activity
Biological Process GO:0045944 positive regulation of transcription by RNA polymerase II
Biological Process GO:0032481 positive regulation of type I interferon production
Biological Process GO:0006355 regulation of transcription, DNA-templated
Biological Process GO:0034097 response to cytokine
Biological Process GO:0032496 response to lipopolysaccharide
Biological Process GO:0048511 rhythmic process
Biological Process GO:0048536 spleen development
molecular function GO:0001228 DNA-binding transcription activator activity, RNA polymerase II-specific
molecular function GO:0003700 DNA-binding transcription factor activity
molecular function GO:0000981 DNA-binding transcription factor activity, RNA polymerase II-specific
molecular function GO:0000978 RNA polymerase II cis-regulatory region sequence-specific DNA binding
molecular function GO:1990837 sequence-specific double-stranded DNA binding
cellular component GO:0033257 Bcl3/NF-kappaB2 complex
cellular component GO:0005737 cytoplasm
cellular component GO:0005829 cytosol
cellular component GO:0042025 host cell nucleus
cellular component GO:0000790 nuclear chromatin
cellular component GO:0005654 nucleoplasm
cellular component GO:0005634 nucleus
Reactome
Pathway Id Pathway Name
R-HSA-1280215 Cytokine Signaling in Immune system
R-HSA-1606322 ZBP1(DAI) mediated induction of type I IFNs
R-HSA-1643685 Disease
R-HSA-166016 Toll Like Receptor 4 (TLR4) Cascade
R-HSA-166058 MyD88:MAL(TIRAP) cascade initiated on plasma membrane
R-HSA-166166 MyD88-independent TLR4 cascade
R-HSA-168138 Toll Like Receptor 9 (TLR9) Cascade
R-HSA-168142 Toll Like Receptor 10 (TLR10) Cascade
R-HSA-168164 Toll Like Receptor 3 (TLR3) Cascade
R-HSA-168176 Toll Like Receptor 5 (TLR5) Cascade
R-HSA-168179 Toll Like Receptor TLR1:TLR2 Cascade
R-HSA-168181 Toll Like Receptor 7/8 (TLR7/8) Cascade
R-HSA-168188 Toll Like Receptor TLR6:TLR2 Cascade
R-HSA-168249 Innate Immune System
R-HSA-168256 Immune System
R-HSA-168643 Nucleotide-binding domain, leucine rich repeat containing receptor (NLR) signaling pathways
R-HSA-168898 Toll-like Receptor Cascades
R-HSA-168928 DDX58/IFIH1-mediated induction of interferon-alpha/beta
R-HSA-1810476 RIP-mediated NFkB activation via ZBP1
R-HSA-181438 Toll Like Receptor 2 (TLR2) Cascade
R-HSA-1834949 Cytosolic sensors of pathogen-associated DNA
R-HSA-2990846 SUMOylation
R-HSA-3108232 SUMO E3 ligases SUMOylate target proteins
R-HSA-3134963 DEx/H-box helicases activate type I IFN and inflammatory cytokines production
R-HSA-3214841 PKMTs methylate histone lysines
R-HSA-3247509 Chromatin modifying enzymes
R-HSA-392499 Metabolism of proteins
R-HSA-445989 TAK1 activates NFkB by phosphorylation and activation of IKKs complex
R-HSA-446652 Interleukin-1 family signaling
R-HSA-448706 Interleukin-1 processing
R-HSA-449147 Signaling by Interleukins
R-HSA-4755510 SUMOylation of immune response proteins
R-HSA-4839726 Chromatin organization
R-HSA-5260271 Diseases of Immune System
R-HSA-5602358 Diseases associated with the TLR signaling cascade
R-HSA-5603029 IkBA variant leads to EDA-ID
R-HSA-5607761 Dectin-1 mediated noncanonical NF-kB signaling
R-HSA-5607764 CLEC7A (Dectin-1) signaling
R-HSA-5621481 C-type lectin receptors (CLRs)
R-HSA-5663205 Infectious disease
R-HSA-5668541 TNFR2 non-canonical NF-kB pathway
R-HSA-5676590 NIK-->noncanonical NF-kB signaling
R-HSA-597592 Post-translational protein modification
R-HSA-622312 Inflammasomes
R-HSA-844456 The NLRP3 inflammasome
R-HSA-9020702 Interleukin-1 signaling
R-HSA-933542 TRAF6 mediated NF-kB activation
R-HSA-937061 TRIF(TICAM1)-mediated TLR4 signaling
R-HSA-9658195 Leishmania infection
R-HSA-9660826 Purinergic signaling in leishmaniasis infection
R-HSA-9664424 Cell recruitment (pro-inflammatory response)
R-HSA-975138 TRAF6 mediated induction of NFkB and MAP kinases upon TLR7/8 or 9 activation
R-HSA-975155 MyD88 dependent cascade initiated on endosome
R-HSA-975871 MyD88 cascade initiated on plasma membrane
Target protein-related  diseases
Disease
CUI Id BXGD Id Disease Name Disease Class
C0001418 BXGD000050 Adenocarcinoma Neoplasms
C0001623 BXGD000066 Adrenal gland hypofunction Endocrine System Diseases
C0002170 BXGD000105 Alopecia Pathological Conditions, Signs and Symptoms; Skin and Connective Tissue Diseases
C0002395 BXGD000111 Alzheimer's Disease Nervous System Diseases; Mental Disorders
C0002878 BXGD000137 Anemia, Hemolytic Hemic and Lymphatic Diseases
C0003466 BXGD000193 Anus, Imperforate Congenital, Hereditary, and Neonatal Diseases and Abnormalities; Digestive System Diseases
C0003467 BXGD000194 Anxiety Behavior and Behavior Mechanisms
C0003469 BXGD000195 Anxiety Disorders Mental Disorders
C0003850 BXGD000225 Arteriosclerosis Cardiovascular Diseases
C0003862 BXGD000230 Arthralgia Pathological Conditions, Signs and Symptoms; Musculoskeletal Diseases
C0004096 BXGD000252 Asthma Respiratory Tract Diseases; Immune System Diseases
C0004153 BXGD000260 Atherosclerosis Cardiovascular Diseases
C0004364 BXGD000270 Autoimmune Diseases Immune System Diseases
C0005586 BXGD000315 Bipolar Disorder Mental Disorders
C0005684 BXGD000319 Malignant neoplasm of urinary bladder Neoplasms; Female Urogenital Diseases and Pregnancy Complications; Male Urogenital Diseases
C0005695 BXGD000323 Bladder Neoplasm Neoplasms; Female Urogenital Diseases and Pregnancy Complications; Male Urogenital Diseases
C0005940 BXGD000352 Bone Diseases Musculoskeletal Diseases
C0006142 BXGD000374 Malignant neoplasm of breast Neoplasms; Skin and Connective Tissue Diseases
C0006267 BXGD000383 Bronchiectasis Respiratory Tract Diseases
C0006413 BXGD000397 Burkitt Lymphoma Neoplasms; Infections; Immune System Diseases; Hemic and Lymphatic Diseases
C0006826 BXGD000408 Malignant Neoplasms Neoplasms
C0007097 BXGD000424 Carcinoma Neoplasms
C0007102 BXGD000425 Malignant tumor of colon Digestive System Diseases; Neoplasms
C0007131 BXGD000441 Non-Small Cell Lung Carcinoma Neoplasms; Respiratory Tract Diseases
C0007134 BXGD000443 Renal Cell Carcinoma Neoplasms; Female Urogenital Diseases and Pregnancy Complications; Male Urogenital Diseases
C0009319 BXGD000596 Colitis Digestive System Diseases
C0009398 BXGD000604 Color vision defect Pathological Conditions, Signs and Symptoms; Eye Diseases; Nervous System Diseases
C0009447 BXGD000613 Common Variable Immunodeficiency Immune System Diseases
C0010823 BXGD000690 Cytomegalovirus Infections Infections
C0011847 BXGD000749 Diabetes Endocrine System Diseases
C0011849 BXGD000751 Diabetes Mellitus Nutritional and Metabolic Diseases; Endocrine System Diseases
C0011853 BXGD000752 Diabetes Mellitus, Experimental Nutritional and Metabolic Diseases; Endocrine System Diseases
C0011854 BXGD000753 Diabetes Mellitus, Insulin-Dependent Nutritional and Metabolic Diseases; Immune System Diseases; Endocrine System Diseases
C0012569 BXGD000777 Diplopia Pathological Conditions, Signs and Symptoms; Eye Diseases; Nervous System Diseases
C0013170 BXGD000802 Drug habituation Chemically-Induced Disorders; Mental Disorders
C0013575 BXGD000854 Ectodermal Dysplasia Congenital, Hereditary, and Neonatal Diseases and Abnormalities; Skin and Connective Tissue Diseases
C0013990 BXGD000874 Pathological accumulation of air in tissues Pathological Conditions, Signs and Symptoms
C0015544 BXGD001003 Failure to Thrive Pathological Conditions, Signs and Symptoms
C0015672 BXGD001011 Fatigue Pathological Conditions, Signs and Symptoms
C0017152 BXGD001096 Gastritis Digestive System Diseases
C0017636 BXGD001131 Glioblastoma Neoplasms
C0018213 BXGD001187 Graves Disease Eye Diseases; Immune System Diseases; Endocrine System Diseases
C0018681 BXGD001214 Headache Pathological Conditions, Signs and Symptoms
C0019196 BXGD001301 Hepatitis C Digestive System Diseases; Infections
C0019829 BXGD001350 Hodgkin Disease Neoplasms; Immune System Diseases; Hemic and Lymphatic Diseases
C0020615 BXGD001445 Hypoglycemia Nutritional and Metabolic Diseases
C0020617 BXGD001446 Hypoglycemic coma Pathological Conditions, Signs and Symptoms; Nutritional and Metabolic Diseases; Nervous System Diseases; Endocrine System Diseases
C0020625 BXGD001451 Hyponatremia Nutritional and Metabolic Diseases
C0020635 BXGD001455 Hypopituitarism Nervous System Diseases; Endocrine System Diseases
C0020649 BXGD001459 Hypotension Cardiovascular Diseases
C0021051 BXGD001475 Immunologic Deficiency Syndromes Immune System Diseases
C0023434 BXGD001643 Chronic Lymphocytic Leukemia Neoplasms; Immune System Diseases; Hemic and Lymphatic Diseases
C0023449 BXGD001650 Acute lymphocytic leukemia Neoplasms; Immune System Diseases; Hemic and Lymphatic Diseases
C0023452 BXGD001651 Childhood Acute Lymphoblastic Leukemia Neoplasms; Immune System Diseases; Hemic and Lymphatic Diseases
C0023467 BXGD001658 Leukemia, Myelocytic, Acute Neoplasms
C0023492 BXGD001671 Leukemia, T-Cell Neoplasms; Immune System Diseases; Hemic and Lymphatic Diseases
C0023493 BXGD001672 Adult T-Cell Lymphoma/Leukemia Neoplasms; Immune System Diseases; Hemic and Lymphatic Diseases
C0024299 BXGD001758 Lymphoma Neoplasms; Immune System Diseases; Hemic and Lymphatic Diseases
C0024312 BXGD001766 Lymphopenia Immune System Diseases; Hemic and Lymphatic Diseases
C0024530 BXGD001783 Malaria Infections
C0024623 BXGD001791 Malignant neoplasm of stomach Digestive System Diseases; Neoplasms
C0025202 BXGD001832 melanoma Neoplasms
C0026764 BXGD001928 Multiple Myeloma Neoplasms; Immune System Diseases; Hemic and Lymphatic Diseases; Cardiovascular Diseases
C0026769 BXGD001930 Multiple Sclerosis Immune System Diseases; Nervous System Diseases
C0026848 BXGD001941 Myopathy Musculoskeletal Diseases; Nervous System Diseases
C0026975 BXGD001954 Myelitis Infections; Nervous System Diseases
C0027022 BXGD001962 Myeloproliferative disease Hemic and Lymphatic Diseases
C0027651 BXGD002009 Neoplasms Neoplasms
C0027873 BXGD002054 Neuromyelitis Optica Eye Diseases; Immune System Diseases; Nervous System Diseases
C0029124 BXGD002113 Optic Atrophy Eye Diseases; Nervous System Diseases
C0029134 BXGD002118 Optic Neuritis Eye Diseases; Nervous System Diseases
C0029401 BXGD002135 Osteitis Deformans Musculoskeletal Diseases
C0029453 BXGD002154 Osteopenia Nutritional and Metabolic Diseases; Musculoskeletal Diseases
C0029454 BXGD002155 Osteopetrosis Musculoskeletal Diseases
C0029456 BXGD002157 Osteoporosis Nutritional and Metabolic Diseases; Musculoskeletal Diseases
C0030567 BXGD002240 Parkinson Disease Nervous System Diseases
C0031485 BXGD002303 Phenylketonurias Congenital, Hereditary, and Neonatal Diseases and Abnormalities; Nutritional and Metabolic Diseases; Nervous System Diseases
C0032002 BXGD002320 Pituitary Diseases Nervous System Diseases; Endocrine System Diseases
C0032285 BXGD002344 Pneumonia Infections; Respiratory Tract Diseases
C0033578 BXGD002408 Prostatic Neoplasms Neoplasms; Male Urogenital Diseases
C0034150 BXGD002466 Purpura Pathological Conditions, Signs and Symptoms; Hemic and Lymphatic Diseases
C0037317 BXGD002689 Sleep disturbances Nervous System Diseases; Mental Disorders; Behavior and Behavior Mechanisms
C0038002 BXGD002723 Splenomegaly Pathological Conditions, Signs and Symptoms
C0042384 BXGD002979 Vasculitis Cardiovascular Diseases
C0079731 BXGD003087 B-Cell Lymphomas Neoplasms; Immune System Diseases; Hemic and Lymphatic Diseases
C0079744 BXGD003090 Diffuse Large B-Cell Lymphoma Neoplasms; Immune System Diseases; Hemic and Lymphatic Diseases
C0079772 BXGD003099 T-Cell Lymphoma Neoplasms; Immune System Diseases; Hemic and Lymphatic Diseases
C0079773 BXGD003100 Lymphoma, T-Cell, Cutaneous Neoplasms; Immune System Diseases; Hemic and Lymphatic Diseases
C0086438 BXGD003283 Hypogammaglobulinemia Immune System Diseases; Hemic and Lymphatic Diseases
C0206180 BXGD004170 Ki-1+ Anaplastic Large Cell Lymphoma Neoplasms; Immune System Diseases; Hemic and Lymphatic Diseases
C0206650 BXGD004214 Fibroadenoma Neoplasms
C0220597 BXGD004292 Adult Hodgkin Lymphoma Neoplasms; Immune System Diseases; Hemic and Lymphatic Diseases
C0220633 BXGD004303 Uveal melanoma Neoplasms; Eye Diseases
C0220644 BXGD004306 Childhood Hodgkin Lymphoma Neoplasms; Immune System Diseases; Hemic and Lymphatic Diseases
C0220668 BXGD004317 Congenital contractural arachnodactyly Congenital, Hereditary, and Neonatal Diseases and Abnormalities; Musculoskeletal Diseases
C0221260 BXGD004424 Dystrophia unguium Pathological Conditions, Signs and Symptoms; Skin and Connective Tissue Diseases
C0221356 BXGD004448 Brachycephaly Congenital, Hereditary, and Neonatal Diseases and Abnormalities; Musculoskeletal Diseases
C0236642 BXGD004815 Pick Disease of the Brain Nervous System Diseases; Mental Disorders
C0238198 BXGD004893 Gastrointestinal Stromal Tumors Digestive System Diseases; Neoplasms
C0238790 BXGD004956 bone destruction
C0242225 BXGD005143 Color blindness Pathological Conditions, Signs and Symptoms; Eye Diseases; Nervous System Diseases
C0242379 BXGD005157 Malignant neoplasm of lung Neoplasms; Respiratory Tract Diseases
C0242422 BXGD005163 Parkinsonian Disorders Nervous System Diseases
C0243026 BXGD005210 Sepsis Pathological Conditions, Signs and Symptoms; Infections
C0262985 BXGD005277 Psoriasiform eczema Skin and Connective Tissue Diseases
C0263504 BXGD005317 Alopecia totalis Pathological Conditions, Signs and Symptoms; Skin and Connective Tissue Diseases; Endocrine System Diseases
C0263912 BXGD005354 Rotator cuff syndrome Wounds and Injuries
C0271441 BXGD006203 Chronic otitis media Otorhinolaryngologic Diseases
C0271561 BXGD006213 Somatotropin deficiency Congenital, Hereditary, and Neonatal Diseases and Abnormalities; Musculoskeletal Diseases; Nervous System Diseases; Endocrine System Diseases
C0271583 BXGD006218 ACTH Deficiency, Isolated Congenital, Hereditary, and Neonatal Diseases and Abnormalities; Nutritional and Metabolic Diseases; Endocrine System Diseases
C0276429 BXGD006422 Enteroviral encephalomyelitis Pathological Conditions, Signs and Symptoms; Infections; Nervous System Diseases
C0278601 BXGD006547 Inflammatory Breast Carcinoma Neoplasms; Skin and Connective Tissue Diseases
C0278764 BXGD006581 Adult Burkitt Lymphoma Neoplasms; Infections; Immune System Diseases; Hemic and Lymphatic Diseases
C0278879 BXGD006610 Childhood Burkitt Lymphoma Neoplasms; Infections; Immune System Diseases; Hemic and Lymphatic Diseases
C0279702 BXGD006685 Conventional (Clear Cell) Renal Cell Carcinoma Neoplasms; Female Urogenital Diseases and Pregnancy Complications; Male Urogenital Diseases
C0333307 BXGD006946 Superficial ulcer Pathological Conditions, Signs and Symptoms
C0338401 BXGD007171 Enteroviral encephalitis Infections; Nervous System Diseases
C0338451 BXGD007176 Frontotemporal dementia Nutritional and Metabolic Diseases; Nervous System Diseases; Mental Disorders
C0339573 BXGD007271 Glaucoma, Primary Open Angle Eye Diseases
C0342388 BXGD007473 Adrenocorticotropic hormone (ACTH) deficiency (disorder) Endocrine System Diseases
C0349632 BXGD007939 Splenic Marginal Zone B-Cell Lymphoma Neoplasms; Immune System Diseases; Hemic and Lymphatic Diseases
C0376407 BXGD007996 Granulomatous Slack Skin Neoplasms; Immune System Diseases; Hemic and Lymphatic Diseases
C0398650 BXGD008212 Immune thrombocytopenic purpura Pathological Conditions, Signs and Symptoms; Immune System Diseases; Hemic and Lymphatic Diseases
C0398686 BXGD008215 Primary immune deficiency disorder Immune System Diseases
C0405580 BXGD008325 Adrenal cortical hypofunction Endocrine System Diseases
C0422943 BXGD008465 Visual symptoms
C0497156 BXGD009053 Lymphadenopathy Hemic and Lymphatic Diseases
C0522274 BXGD009200 Humoral immune defect Immune System Diseases; Hemic and Lymphatic Diseases
C0557874 BXGD009444 Global developmental delay
C0581354 BXGD009561 Recurrent sinusitis Infections; Respiratory Tract Diseases; Otorhinolaryngologic Diseases
C0596263 BXGD009639 Carcinogenesis Pathological Conditions, Signs and Symptoms; Neoplasms
C0598766 BXGD009669 Leukemogenesis Pathological Conditions, Signs and Symptoms; Neoplasms
C0678222 BXGD009749 Breast Carcinoma Neoplasms; Skin and Connective Tissue Diseases
C0684249 BXGD009790 Carcinoma of lung Neoplasms; Respiratory Tract Diseases
C0687720 BXGD009844 Central Diabetes Insipidus Female Urogenital Diseases and Pregnancy Complications; Male Urogenital Diseases; Endocrine System Diseases
C0694550 BXGD009852 Recurrent pneumonia Infections; Respiratory Tract Diseases
C0699790 BXGD009866 Colon Carcinoma Digestive System Diseases; Neoplasms
C0699791 BXGD009867 Stomach Carcinoma Digestive System Diseases; Neoplasms
C0699885 BXGD009869 Carcinoma of bladder Neoplasms; Female Urogenital Diseases and Pregnancy Complications; Male Urogenital Diseases
C0700201 BXGD009880 Dyssomnias Nervous System Diseases; Mental Disorders
C0700613 BXGD009896 Anxiety state Mental Disorders; Behavior and Behavior Mechanisms
C0741796 BXGD010041 Recurrent bronchitis Infections; Respiratory Tract Diseases
C0747085 BXGD010158 Recurrent otitis media Otorhinolaryngologic Diseases
C0747556 BXGD010173 Recurrent pharyngitis Infections; Respiratory Tract Diseases; Stomatognathic Diseases; Otorhinolaryngologic Diseases
C0851578 BXGD010925 Sleep Disorders Pathological Conditions, Signs and Symptoms; Nervous System Diseases; Mental Disorders
C0948387 BXGD011535 Secondary Adrenal Insufficiency Endocrine System Diseases
C1262020 BXGD011864 Diffuse alveolar damage
C1269955 BXGD012005 Tumor Cell Invasion
C1276146 BXGD012107 Cutaneous lymphoma Neoplasms; Immune System Diseases; Hemic and Lymphatic Diseases
C1279420 BXGD012122 Anxiety neurosis (finding) Mental Disorders
C1292753 BXGD012226 Primary Effusion Lymphoma Neoplasms; Immune System Diseases; Hemic and Lymphatic Diseases
C1302772 BXGD012311 Primary cutaneous lymphoma Neoplasms; Skin and Connective Tissue Diseases; Immune System Diseases; Hemic and Lymphatic Diseases
C1306459 BXGD012361 Primary malignant neoplasm Neoplasms
C1306460 BXGD012362 Primary malignant neoplasm of lung Neoplasms; Respiratory Tract Diseases
C1332206 BXGD012504 Adult Lymphoma Neoplasms; Immune System Diseases; Hemic and Lymphatic Diseases
C1332979 BXGD012571 Childhood Lymphoma Neoplasms; Immune System Diseases; Hemic and Lymphatic Diseases
C1400201 BXGD013012 Pituitary anomalies
C1458155 BXGD013136 Mammary Neoplasms Neoplasms; Skin and Connective Tissue Diseases
C1621958 BXGD013468 Glioblastoma Multiforme Neoplasms
C1833662 BXGD013936 INCLUSION BODY MYOPATHY WITH EARLY-ONSET PAGET DISEASE AND FRONTOTEMPORAL DEMENTIA Congenital, Hereditary, and Neonatal Diseases and Abnormalities; Nutritional and Metabolic Diseases; Musculoskeletal Diseases; Nervous System Diseases; Mental Disorders
C1836623 BXGD014139 Decreased circulating cortisol level Immune System Diseases; Endocrine System Diseases
C1837066 BXGD014190 Recurrent viral infection Infections
C1844666 BXGD014657 Immune dysregulation
C1846288 BXGD014796 Recurrent hypoglycemia Nutritional and Metabolic Diseases
C1848389 BXGD014920 Posterior pharyngeal cleft
C1848701 BXGD014967 Elevated hepatic transaminase
C1861403 BXGD016045 Variable expressivity
C1863715 BXGD016190 Severe B lymphocytopenia
C1867873 BXGD016473 Failure to thrive in infancy
C1868683 BXGD016526 B-CELL MALIGNANCY, LOW-GRADE
C1961102 BXGD016673 Precursor Cell Lymphoblastic Leukemia Lymphoma Neoplasms; Immune System Diseases; Hemic and Lymphatic Diseases
C2748557 BXGD017597 Immune dysfunction with T-cell inactivation due to calcium entry defect 2 Congenital, Hereditary, and Neonatal Diseases and Abnormalities; Nutritional and Metabolic Diseases; Immune System Diseases
C2936664 BXGD018125 Acquired Hypogammaglobulinemia Immune System Diseases
C2936665 BXGD018126 Immunoglobulin Deficiency, Late-Onset Immune System Diseases
C2937358 BXGD018159 Cerebral Hemorrhage Pathological Conditions, Signs and Symptoms; Nervous System Diseases; Cardiovascular Diseases
C3149378 BXGD018279 IMMUNODEFICIENCY, COMMON VARIABLE, 1
C3277226 BXGD018711 Restrictive ventilatory defect
C3539878 BXGD019087 Triple Negative Breast Neoplasms Neoplasms; Skin and Connective Tissue Diseases
C3714636 BXGD019421 Pneumonitis Infections; Respiratory Tract Diseases
C3714796 BXGD019434 Isolated somatotropin deficiency
C3806482 BXGD019514 Recurrent respiratory infections Infections; Respiratory Tract Diseases
C3809991 BXGD019627 IMMUNODEFICIENCY, COMMON VARIABLE, 10
C3854222 BXGD019826 Human immunodeficiency virus (HIV) II infection category B1
C3887524 BXGD019892 Skin Erosion Skin and Connective Tissue Diseases
C4021966 BXGD020845 Abnormality of the periungual region Pathological Conditions, Signs and Symptoms
C4022874 BXGD021025 Abnormal size of pituitary gland Nervous System Diseases; Endocrine System Diseases
C4023211 BXGD021145 Adrenocorticotropin deficient adrenal insufficiency
C4025669 BXGD021720 Decreased circulating ACTH level
C4048270 BXGD021897 Decreased antibody level in blood
C4072894 BXGD022015 Decreased circulating androgen level
C4072897 BXGD022016 Decreased serum insulin-like growth factor 1
C4275242 BXGD022371 Sudden sensorineural hearing loss Pathological Conditions, Signs and Symptoms; Nervous System Diseases; Otorhinolaryngologic Diseases
C4316903 BXGD022711 Absence Seizures Pathological Conditions, Signs and Symptoms; Nervous System Diseases
C4722518 BXGD023806 Triple-Negative Breast Carcinoma Neoplasms; Skin and Connective Tissue Diseases
Target protein-related  compounds
Compounds
BXGC Id Compound Name Strcuture Molecular Weight
BXGC0000016 Butein 272.25
BXGC0000194 Sanguinarine 332.33
BXGC0000314 Isorhamnetin 316.26
BXGC0000340 Kaempferol 286.24
BXGC0000363 Galangin 270.24
BXGC0000516 Diosmetin 300.26
BXGC0001767 (E)-Resveratrol 228.25
BXGC0001837 Quercetin 3-rutinoside 610.52
BXGC0001876 Chrysoeriol 300.26
BXGC0002043 Acacetin 284.26
BXGC0002071 Apigenin 270.24
BXGC0002101 2',4-Dihydroxy-4',6'-dimethoxychalcone 300.31
BXGC0003328 Tetrahydrocurcumin 372.41
BXGC0003452 Pectolinarigenin 314.29
BXGC0003501 Parthenolide 248.32
BXGC0003507 Santamarin 248.32
BXGC0005678 Quercetagetin 318.24
BXGC0005683 Quercetin 302.24
BXGC0005767 Geraldone 284.26
BXGC0005915 Formononetin 268.27
BXGC0005919 Biochanin A 284.27
BXGC0006635 Luteolin 286.24
BXGC0008184 Phloretin 274.27
BXGC0008707 Isoliquiritigenin 256.25
BXGC0008747 Tamarixetin 316.26
BXGC0008840 Kaempferide 300.26
BXGC0008877 Homoeriodictyol 302.28
BXGC0008894 Dihydroisorhamnetin 318.28
BXGC0011740 1'-Acetoxychavicol 234.25
BXGC0012377 Nagilactone B 364.15
BXGC0013008 6-O-Acetyldihydrohelenalin 306.15
BXGC0013582 Curcumin 368.13
BXGC0014407 tatridin B 264.14
BXGC0014529 GUAIANOLIDE 328.13
BXGC0014649 4',7-Dimethoxy-5-Hydroxygenistein 298.08
BXGC0015766 Andrographolide 350.21
BXGC0016149 Goniothalamin 200.08
BXGC0016639 cumambrin B 264.14
BXGC0016964 cumambrin A 306.15
BXGC0017405 Ludovicin A 264.14
BXGC0017965 4-Hydroxycoumarins 162.03
BXGC0019095 ecliptasaponin A 634.41
BXGC0020302 Hortiacine 317.12
BXGC0020903 molephantinin 360.16
BXGC0024141 Hydrocortisone 362.21
BXGC0024774 Goiazensolide 360.12
BXGC0025200 2-Anilinonaphthalene-1,4-Dione 249.08
BXGC0025342 Mexicanin I 262.12
BXGC0026595 Glycyrrhizin 822.4
BXGC0028001 Beta-Lapachone 242.09
BXGC0029810 1,5-Bis(4-Hydroxy-3-Methoxyphenyl)-1,4-Pentadien-3-One 326.12
BXGC0031011 douglanin 248.14
BXGC0032711 Zaluzanin D 288.14
BXGC0033693 arnicolide D 332.16
BXGC0033917 Homobutein 286.08
BXGC0035783 8-Deoxylactucin 260.1
BXGC0036318 Gossypetin 318.04
BXGC0036509 molephantin 346.14
BXGC0036860 Helenalin 262.12
BXGC0038891 2,3-Dihydroaromaticin 248.14
BXGC0039578 costunolide 232.15
BXGC0040364 Artesunate 384.18
BXGC0040563 Dehydroleucodin 244.11
BXGC0043743 Lantadene A 552.38
BXGC0046510 Tpck 351.07
BXGC0047160 Plenolin 264.14
BXGC0049832 isosclerone 178.06
BXGC0050219 Helenalinisobutyrate 332.16
BXGC0051204 2-Deethoxy-2beta-methoxyphantomolin 360.16
BXGC0053029 22Beta-Senecioyloxy-3-Oxo-Olean-12-En-28-Oic Acid 552.38
BXGC0053398 tamirin 262.12
The  target protein-related  foods
Foods
BXGF Id Food Name Scientific Name Food Group Number of compound? Number of compound in food, higher numbers indicate the food are more associated with the protein