acompound

Showing entry for 4-hydroxyphenylpyruvic acid

　　　　　　　　　　　　　　　

General Compound Information
BXGC Id	BXGC0017154
Compound Name	4-hydroxyphenylpyruvic acid
Structure
Formula	C9H8O4
InchiKey	KKADPXVIOXHVKN-UHFFFAOYSA-N
SMILES	Oc1ccc(cc1)CC(=O)C(=O)O
Inchi	InChI=1S/C9H8O4/c10-7-3-1-6(2-4-7)5-8(11)9(12)13/h1-4,10H,5H2,(H,12,13)
IUPAC	3-(4-hydroxyphenyl)-2-oxopropanoic acid
Molecular Weight	180.04
Pubchem Id	979
Chembl Id	CHEMBL607712

Targets of Information Source

DrugBank

Uniport Id	BXGT Id	Protein Name	Status	Protein Class	Gene	Groups	Target Type
Uniport Id	BXGT Id	Protein Name	Status	Protein Class	Gene	Groups	Target Type
P00734	BXGT005630	Prothrombin	reviewed	Enzyme	F2	experimental	-
P14174	BXGT007991	Macrophage migration inhibitory factor	reviewed	-	MIF	experimental	-
O67636	BXGT005001	Prephenate dehydrogenase	unreviewed	-	tyrA	experimental	-

PDB

Uniport Id	BXGT Id	Protein Name	Status	Protein Class	Gene	Ki nM	ic50 nM	Kd nM	Ka M-1
Uniport Id	BXGT Id	Protein Name	Status	Protein Class	Gene	Ki nM	ic50 nM	Kd nM	Ka M-1
P14174	BXGT007991	Macrophage migration inhibitory factor	reviewed	MIF	-	-	-	-	-
Q1HEA2	BXGT013797	Macrophage migration inhibitory factor-like protein	unreviewed	mif	-	-	-	-	-
O67636	BXGT005001	Prephenate dehydrogenase	unreviewed	tyrA	-	-	-	-	-
Q6N8W4	BXGT016397	Putative branched-chain amino acid transport system substrate-binding protein	unreviewed	RPA1789	-	-	-	-	-
Q139W5	BXGT013410	Extracellular ligand-binding receptor	unreviewed	RPD_1889	-	-	-	-	-
Q2IU40	BXGT014104	Extracellular ligand-binding receptor	unreviewed	RPB_3575	-	-	-	-	-
Q643C8	BXGT016118	Phenylpyruvate C(3)-methyltransferase	reviewed	mppJ	-	-	-	-	-
L8NZJ8	BXGT023615	Cupin domain protein	unreviewed	aerE	-	-	-	-	-
L8NWH6	BXGT024485	Short chain dehydrogenase family protein	unreviewed	aerF	-	-	-	-	-

Binding DB

n.a

Uniport Id	BXGT Id	Protein Name	Status	Protein Class	Gene	Ki nM	ic50 nM	Kd nM	EC50 nM
Uniport Id	BXGT Id	Protein Name	Status	Protein Class	Gene	Ki nM	ic50 nM	Kd nM	EC50 nM

CHEMBL

Uniport Id	BXGT Id	Protein Name	Status	Protein Class	Gene	width="10%">Type	Relation	value	Units
Uniport Id	BXGT Id	Protein Name	Status	Protein Class	Gene	Type	Relation	value	Units
Q8VC69	BXGT018912	Solute carrier family 22 member 6	reviewed	-	Slc22a6	Ki	'='	73000	nM
P14174	BXGT007991	Macrophage migration inhibitory factor	reviewed	-	MIF	Km	'='	322000	nM
Q80UJ1	BXGT017282	Solute carrier family 22 member 20	reviewed	-	Slc22a20	Ki	'='	66069	nM
P14174	BXGT007991	Macrophage migration inhibitory factor	reviewed	-	MIF	Km	'='	444000	nM
P14174	BXGT007991	Macrophage migration inhibitory factor	reviewed	-	MIF	Km	'='	533000	nM
Q80UJ1	BXGT017282	Solute carrier family 22 member 20	reviewed	-	Slc22a20	Ki	'='	66000	nM
Q8VC69	BXGT018912	Solute carrier family 22 member 6	reviewed	-	Slc22a6	Ki	'='	72443	nM

Foods containing the compound

Foods

BXGF Id	Food Name	Scientific Name	Food Group
BXGF Id	Food Name	Scientific Name	Food Group
BXGF05753	Citrus limonia	Citrus limonia	Medicinal Plant

The compound-realted diseases

Diseases

BXGD Id	Disease Name	CUI Disease Id	Disease Class Name	Number of targets^{?Number of targets related to compound connecting disease, higher numbers indicate the compound is more associated with the disease}