Showing entry for Prothrombin


　 　 　 　 　 　 　 　 　 　 　 　
General Target Information
BXGT IdBXGT005630
Protein NameProthrombin
Uniport IdP00734
GeneF2
Gene Id2147
DomainGla; Kringle; Thrombin_light; Trypsin
Pfam PF00594   PF00051   PF09396   PF00089  
OrganismHomo sapiens (Human)
Target protein  affiliated  biological  pathways
KEGG
Class Subclass KEGG Id Pathway Name
3. Environmental Information Processing 3.2 Signal transduction hsa04072 Phospholipase D signaling pathway
3. Environmental Information Processing 3.3 Signaling molecules and interaction hsa04080 Neuroactive ligand-receptor interaction
5. Organismal Systems 5.1 Immune system hsa04610 Complement and coagulation cascades
5. Organismal Systems 5.1 Immune system hsa04611 Platelet activation
4. Cellular Processes 4.5 Cell motility hsa04810 Regulation of actin cytoskeleton
6. Human Diseases 6.1 Cancers: Overview hsa05200 Pathways in cancer
Gene Ontology
GO Type GO Id Gene Ontology
Biological Process GO:0006953 acute-phase response
Biological Process GO:0061844 antimicrobial humoral immune response mediated by antimicrobial peptide
Biological Process GO:0007596 blood coagulation
Biological Process GO:0007597 blood coagulation, intrinsic pathway
Biological Process GO:0007166 cell surface receptor signaling pathway
Biological Process GO:0044267 cellular protein metabolic process
Biological Process GO:0051838 cytolysis by host of symbiont cells
Biological Process GO:0006888 endoplasmic reticulum to Golgi vesicle-mediated transport
Biological Process GO:0042730 fibrinolysis
Biological Process GO:0007186 G protein-coupled receptor signaling pathway
Biological Process GO:0050900 leukocyte migration
Biological Process GO:0007275 multicellular organism development
Biological Process GO:0048712 negative regulation of astrocyte differentiation
Biological Process GO:1900016 negative regulation of cytokine production involved in inflammatory response
Biological Process GO:0051918 negative regulation of fibrinolysis
Biological Process GO:0010544 negative regulation of platelet activation
Biological Process GO:0045861 negative regulation of proteolysis
Biological Process GO:0070945 neutrophil-mediated killing of gram-negative bacterium
Biological Process GO:0030168 platelet activation
Biological Process GO:0030194 positive regulation of blood coagulation
Biological Process GO:0030307 positive regulation of cell growth
Biological Process GO:0008284 positive regulation of cell population proliferation
Biological Process GO:0032967 positive regulation of collagen biosynthetic process
Biological Process GO:0090218 positive regulation of lipid kinase activity
Biological Process GO:0014068 positive regulation of phosphatidylinositol 3-kinase signaling
Biological Process GO:1900738 positive regulation of phospholipase C-activating G protein-coupled receptor signaling pathway
Biological Process GO:1900182 positive regulation of protein localization to nucleus
Biological Process GO:0001934 positive regulation of protein phosphorylation
Biological Process GO:2000379 positive regulation of reactive oxygen species metabolic process
Biological Process GO:0046427 positive regulation of receptor signaling pathway via JAK-STAT
Biological Process GO:0051281 positive regulation of release of sequestered calcium ion into cytosol
Biological Process GO:0006508 proteolysis
Biological Process GO:0030193 regulation of blood coagulation
Biological Process GO:0008360 regulation of cell shape
Biological Process GO:0030449 regulation of complement activation
Biological Process GO:0051480 regulation of cytosolic calcium ion concentration
Biological Process GO:0009611 response to wounding
molecular function GO:0005509 calcium ion binding
molecular function GO:0008083 growth factor activity
molecular function GO:0008201 heparin binding
molecular function GO:0001530 lipopolysaccharide binding
molecular function GO:0004252 serine-type endopeptidase activity
molecular function GO:0005102 signaling receptor binding
molecular function GO:0070053 thrombospondin receptor activity
cellular component GO:0072562 blood microparticle
cellular component GO:0062023 collagen-containing extracellular matrix
cellular component GO:0005788 endoplasmic reticulum lumen
cellular component GO:0070062 extracellular exosome
cellular component GO:0005576 extracellular region
cellular component GO:0005615 extracellular space
cellular component GO:0005796 Golgi lumen
cellular component GO:0005886 plasma membrane
Reactome
Pathway Id Pathway Name
R-HSA-109582 Hemostasis
R-HSA-140837 Intrinsic Pathway of Fibrin Clot Formation
R-HSA-140875 Common Pathway of Fibrin Clot Formation
R-HSA-140877 Formation of Fibrin Clot (Clotting Cascade)
R-HSA-159740 Gamma-carboxylation of protein precursors
R-HSA-159763 Transport of gamma-carboxylated protein precursors from the endoplasmic reticulum to the Golgi apparatus
R-HSA-159782 Removal of aminoterminal propeptides from gamma-carboxylated proteins
R-HSA-159854 Gamma-carboxylation, transport, and amino-terminal cleavage of proteins
R-HSA-162582 Signal Transduction
R-HSA-163841 Gamma carboxylation, hypusine formation and arylsulfatase activation
R-HSA-1643685 Disease
R-HSA-166658 Complement cascade
R-HSA-168249 Innate Immune System
R-HSA-168256 Immune System
R-HSA-202733 Cell surface interactions at the vascular wall
R-HSA-372790 Signaling by GPCR
R-HSA-373076 Class A/1 (Rhodopsin-like receptors)
R-HSA-375276 Peptide ligand-binding receptors
R-HSA-381426 Regulation of Insulin-like Growth Factor (IGF) transport and uptake by Insulin-like Growth Factor Binding Proteins (IGFBPs)
R-HSA-388396 GPCR downstream signalling
R-HSA-392499 Metabolism of proteins
R-HSA-416476 G alpha (q) signalling events
R-HSA-456926 Thrombin signalling through proteinase activated receptors (PARs)
R-HSA-500792 GPCR ligand binding
R-HSA-597592 Post-translational protein modification
R-HSA-76002 Platelet activation, signaling and aggregation
R-HSA-76009 Platelet Aggregation (Plug Formation)
R-HSA-9651496 Defects of contact activation system (CAS) and kallikrein/kinin system (KKS)
R-HSA-9657688 Defective factor XII causes hereditary angioedema
R-HSA-9662001 Defective factor VIII causes hemophilia A
R-HSA-9671793 Diseases of hemostasis
R-HSA-9672391 Defective F8 cleavage by thrombin
R-HSA-977606 Regulation of Complement cascade
Target protein-related  diseases
Disease
CUI Id BXGD Id Disease Name Disease Class
C0000737 BXGD000005 Abdominal Pain Pathological Conditions, Signs and Symptoms
C0000768 BXGD000007 Congenital Abnormality Congenital, Hereditary, and Neonatal Diseases and Abnormalities
C0000809 BXGD000011 Abortion, Habitual Female Urogenital Diseases and Pregnancy Complications
C0001339 BXGD000041 Acute pancreatitis Digestive System Diseases
C0001973 BXGD000095 Alcoholic Intoxication, Chronic Chemically-Induced Disorders; Mental Disorders
C0002395 BXGD000111 Alzheimer's Disease Nervous System Diseases; Mental Disorders
C0002871 BXGD000132 Anemia Hemic and Lymphatic Diseases
C0002875 BXGD000135 Cooley's anemia Congenital, Hereditary, and Neonatal Diseases and Abnormalities; Hemic and Lymphatic Diseases
C0002878 BXGD000137 Anemia, Hemolytic Hemic and Lymphatic Diseases
C0002895 BXGD000152 Anemia, Sickle Cell Congenital, Hereditary, and Neonatal Diseases and Abnormalities; Hemic and Lymphatic Diseases
C0002965 BXGD000162 Angina, Unstable Pathological Conditions, Signs and Symptoms; Cardiovascular Diseases
C0003811 BXGD000222 Cardiac Arrhythmia Pathological Conditions, Signs and Symptoms; Cardiovascular Diseases
C0003838 BXGD000224 Arterial Occlusive Diseases Cardiovascular Diseases
C0003850 BXGD000225 Arteriosclerosis Cardiovascular Diseases
C0003855 BXGD000227 Arteriovenous fistula Pathological Conditions, Signs and Symptoms; Congenital, Hereditary, and Neonatal Diseases and Abnormalities; Cardiovascular Diseases
C0003857 BXGD000228 Congenital arteriovenous malformation Congenital, Hereditary, and Neonatal Diseases and Abnormalities; Cardiovascular Diseases
C0003873 BXGD000236 Rheumatoid Arthritis Skin and Connective Tissue Diseases; Musculoskeletal Diseases; Immune System Diseases
C0003962 BXGD000244 Ascites Pathological Conditions, Signs and Symptoms
C0004153 BXGD000260 Atherosclerosis Cardiovascular Diseases
C0004238 BXGD000262 Atrial Fibrillation Pathological Conditions, Signs and Symptoms; Cardiovascular Diseases
C0004610 BXGD000281 Bacteremia Pathological Conditions, Signs and Symptoms; Infections
C0004623 BXGD000282 Bacterial Infections Infections
C0004626 BXGD000283 Pneumonia, Bacterial Infections; Respiratory Tract Diseases
C0004943 BXGD000297 Behcet Syndrome Congenital, Hereditary, and Neonatal Diseases and Abnormalities; Eye Diseases; Skin and Connective Tissue Diseases; Stomatognathic Diseases; Cardiovascular Diseases
C0005129 BXGD000304 Bernard-Soulier Syndrome Congenital, Hereditary, and Neonatal Diseases and Abnormalities; Hemic and Lymphatic Diseases
C0005283 BXGD000308 beta Thalassemia Congenital, Hereditary, and Neonatal Diseases and Abnormalities; Hemic and Lymphatic Diseases
C0005411 BXGD000313 Biliary Atresia Congenital, Hereditary, and Neonatal Diseases and Abnormalities; Digestive System Diseases
C0005779 BXGD000336 Blood Coagulation Disorders Hemic and Lymphatic Diseases
C0006142 BXGD000374 Malignant neoplasm of breast Neoplasms; Skin and Connective Tissue Diseases
C0006826 BXGD000408 Malignant Neoplasms Neoplasms
C0007134 BXGD000443 Renal Cell Carcinoma Neoplasms; Female Urogenital Diseases and Pregnancy Complications; Male Urogenital Diseases
C0007222 BXGD000454 Cardiovascular Diseases Cardiovascular Diseases
C0007282 BXGD000458 Carotid Stenosis Nervous System Diseases; Cardiovascular Diseases
C0007570 BXGD000467 Celiac Disease Digestive System Diseases; Nutritional and Metabolic Diseases
C0007722 BXGD000474 Cephalhematoma due to birth trauma Pathological Conditions, Signs and Symptoms; Congenital, Hereditary, and Neonatal Diseases and Abnormalities; Nervous System Diseases; Wounds and Injuries
C0007785 BXGD000485 Cerebral Infarction Pathological Conditions, Signs and Symptoms; Nervous System Diseases; Cardiovascular Diseases
C0007786 BXGD000486 Brain Ischemia Nervous System Diseases; Cardiovascular Diseases
C0007787 BXGD000487 Transient Ischemic Attack Nervous System Diseases; Cardiovascular Diseases
C0007789 BXGD000488 Cerebral Palsy Nervous System Diseases
C0007820 BXGD000491 Cerebrovascular Disorders Nervous System Diseases; Cardiovascular Diseases
C0008074 BXGD000519 Child Development Disorders, Pervasive Mental Disorders
C0008533 BXGD000556 Hemophilia B Congenital, Hereditary, and Neonatal Diseases and Abnormalities; Hemic and Lymphatic Diseases
C0009324 BXGD000597 Ulcerative Colitis Digestive System Diseases
C0009375 BXGD000602 Colonic Neoplasms Digestive System Diseases; Neoplasms
C0009402 BXGD000605 Colorectal Carcinoma Digestive System Diseases; Neoplasms
C0010054 BXGD000647 Coronary Arteriosclerosis Cardiovascular Diseases
C0010068 BXGD000648 Coronary heart disease Cardiovascular Diseases
C0010072 BXGD000649 Coronary Thrombosis Cardiovascular Diseases
C0010346 BXGD000664 Crohn Disease Digestive System Diseases
C0010481 BXGD000673 Cushing Syndrome Endocrine System Diseases
C0010674 BXGD000683 Cystic Fibrosis Congenital, Hereditary, and Neonatal Diseases and Abnormalities; Digestive System Diseases; Respiratory Tract Diseases
C0011175 BXGD000701 Dehydration Pathological Conditions, Signs and Symptoms; Nutritional and Metabolic Diseases
C0011265 BXGD000708 Presenile dementia Nervous System Diseases; Mental Disorders
C0011847 BXGD000749 Diabetes Endocrine System Diseases
C0011849 BXGD000751 Diabetes Mellitus Nutritional and Metabolic Diseases; Endocrine System Diseases
C0011854 BXGD000753 Diabetes Mellitus, Insulin-Dependent Nutritional and Metabolic Diseases; Immune System Diseases; Endocrine System Diseases
C0011860 BXGD000755 Diabetes Mellitus, Non-Insulin-Dependent Nutritional and Metabolic Diseases; Endocrine System Diseases
C0011884 BXGD000762 Diabetic Retinopathy Eye Diseases; Endocrine System Diseases; Cardiovascular Diseases
C0012739 BXGD000786 Disseminated Intravascular Coagulation Hemic and Lymphatic Diseases
C0013295 BXGD000812 Duodenal Ulcer Digestive System Diseases
C0013404 BXGD000833 Dyspnea Pathological Conditions, Signs and Symptoms; Respiratory Tract Diseases
C0013491 BXGD000847 Ecchymosis Pathological Conditions, Signs and Symptoms; Hemic and Lymphatic Diseases
C0013537 BXGD000853 Eclampsia Female Urogenital Diseases and Pregnancy Complications
C0013922 BXGD000868 Embolism Cardiovascular Diseases
C0014121 BXGD000895 Bacterial Endocarditis Infections; Cardiovascular Diseases
C0014175 BXGD000904 Endometriosis Female Urogenital Diseases and Pregnancy Complications
C0014457 BXGD000915 Eosinophilia Hemic and Lymphatic Diseases
C0014544 BXGD000926 Epilepsy Nervous System Diseases
C0014591 BXGD000938 Epistaxis Pathological Conditions, Signs and Symptoms; Respiratory Tract Diseases; Otorhinolaryngologic Diseases
C0014867 BXGD000964 Esophageal Varices Digestive System Diseases
C0015503 BXGD000998 Factor VII Deficiency Congenital, Hereditary, and Neonatal Diseases and Abnormalities; Hemic and Lymphatic Diseases
C0015519 BXGD000999 Factor X Deficiency Congenital, Hereditary, and Neonatal Diseases and Abnormalities; Hemic and Lymphatic Diseases
C0015530 BXGD001002 Hereditary Factor XIII Deficiency Congenital, Hereditary, and Neonatal Diseases and Abnormalities; Hemic and Lymphatic Diseases
C0015695 BXGD001013 Fatty Liver Digestive System Diseases
C0015934 BXGD001026 Fetal Growth Retardation Pathological Conditions, Signs and Symptoms; Congenital, Hereditary, and Neonatal Diseases and Abnormalities; Female Urogenital Diseases and Pregnancy Complications
C0015967 BXGD001030 Fever Pathological Conditions, Signs and Symptoms
C0016053 BXGD001041 Fibromyalgia Musculoskeletal Diseases; Nervous System Diseases
C0016522 BXGD001067 Foramen Ovale, Patent Congenital, Hereditary, and Neonatal Diseases and Abnormalities; Cardiovascular Diseases
C0017181 BXGD001103 Gastrointestinal Hemorrhage Pathological Conditions, Signs and Symptoms; Digestive System Diseases
C0017565 BXGD001118 Gingival Hemorrhage Pathological Conditions, Signs and Symptoms; Stomatognathic Diseases
C0017605 BXGD001126 Angle Closure Glaucoma Eye Diseases
C0017606 BXGD001127 Primary angle-closure glaucoma Eye Diseases
C0017636 BXGD001131 Glioblastoma Neoplasms
C0017638 BXGD001132 Glioma Neoplasms
C0017921 BXGD001152 Glycogen storage disease type II Congenital, Hereditary, and Neonatal Diseases and Abnormalities; Nutritional and Metabolic Diseases; Nervous System Diseases
C0018799 BXGD001224 Heart Diseases Cardiovascular Diseases
C0018801 BXGD001226 Heart failure Cardiovascular Diseases
C0018802 BXGD001227 Congestive heart failure Cardiovascular Diseases
C0018817 BXGD001235 Atrial Septal Defects Congenital, Hereditary, and Neonatal Diseases and Abnormalities; Cardiovascular Diseases
C0018824 BXGD001237 Heart valve disease Cardiovascular Diseases
C0018924 BXGD001249 Hemarthrosis Pathological Conditions, Signs and Symptoms; Musculoskeletal Diseases
C0018926 BXGD001250 Hematemesis Pathological Conditions, Signs and Symptoms; Digestive System Diseases
C0018939 BXGD001253 Hematological Disease Hemic and Lymphatic Diseases
C0018965 BXGD001258 Hematuria Pathological Conditions, Signs and Symptoms; Female Urogenital Diseases and Pregnancy Complications; Male Urogenital Diseases
C0019069 BXGD001277 Hemophilia A Congenital, Hereditary, and Neonatal Diseases and Abnormalities; Hemic and Lymphatic Diseases
C0019080 BXGD001279 Hemorrhage Pathological Conditions, Signs and Symptoms
C0019087 BXGD001280 Hemorrhagic Disorders Hemic and Lymphatic Diseases
C0019099 BXGD001282 Hemorrhagic Fever, Crimean Infections
C0019100 BXGD001283 Severe Dengue Infections
C0019151 BXGD001290 Hepatic Encephalopathy Digestive System Diseases; Nutritional and Metabolic Diseases; Nervous System Diseases
C0019154 BXGD001291 Hepatic Vein Thrombosis Digestive System Diseases; Cardiovascular Diseases
C0019158 BXGD001293 Hepatitis Digestive System Diseases
C0019159 BXGD001294 Hepatitis A Digestive System Diseases; Infections
C0019163 BXGD001295 Hepatitis B Digestive System Diseases; Infections
C0019196 BXGD001301 Hepatitis C Digestive System Diseases; Infections
C0019214 BXGD001307 Hepatosplenomegaly Pathological Conditions, Signs and Symptoms; Digestive System Diseases; Hemic and Lymphatic Diseases
C0020433 BXGD001379 Hyperbilirubinemia Pathological Conditions, Signs and Symptoms
C0020456 BXGD001392 Hyperglycemia Nutritional and Metabolic Diseases
C0020473 BXGD001396 Hyperlipidemia Nutritional and Metabolic Diseases
C0020532 BXGD001420 Hypersplenism Hemic and Lymphatic Diseases
C0020538 BXGD001422 Hypertensive disease Cardiovascular Diseases
C0020542 BXGD001425 Pulmonary Hypertension Respiratory Tract Diseases
C0020550 BXGD001429 Hyperthyroidism Endocrine System Diseases
C0020564 BXGD001433 Hypertrophy Pathological Conditions, Signs and Symptoms
C0020640 BXGD001458 Inherited Factor II deficiency Congenital, Hereditary, and Neonatal Diseases and Abnormalities; Hemic and Lymphatic Diseases
C0021368 BXGD001502 Inflammation Pathological Conditions, Signs and Symptoms
C0021390 BXGD001503 Inflammatory Bowel Diseases Digestive System Diseases
C0022104 BXGD001529 Irritable Bowel Syndrome Digestive System Diseases
C0022346 BXGD001537 Icterus Pathological Conditions, Signs and Symptoms
C0022650 BXGD001568 Kidney Calculi Pathological Conditions, Signs and Symptoms; Female Urogenital Diseases and Pregnancy Complications; Male Urogenital Diseases
C0022658 BXGD001570 Kidney Diseases Female Urogenital Diseases and Pregnancy Complications; Male Urogenital Diseases
C0022660 BXGD001571 Kidney Failure, Acute Female Urogenital Diseases and Pregnancy Complications; Male Urogenital Diseases
C0022661 BXGD001572 Kidney Failure, Chronic Female Urogenital Diseases and Pregnancy Complications; Male Urogenital Diseases
C0022735 BXGD001581 Klinefelter Syndrome Congenital, Hereditary, and Neonatal Diseases and Abnormalities; Female Urogenital Diseases and Pregnancy Complications; Male Urogenital Diseases; Endocrine System Diseases
C0023223 BXGD001621 Leg Ulcer Skin and Connective Tissue Diseases
C0023449 BXGD001650 Acute lymphocytic leukemia Neoplasms; Immune System Diseases; Hemic and Lymphatic Diseases
C0023452 BXGD001651 Childhood Acute Lymphoblastic Leukemia Neoplasms; Immune System Diseases; Hemic and Lymphatic Diseases
C0023462 BXGD001654 Acute Megakaryocytic Leukemias Neoplasms
C0023465 BXGD001656 Acute monocytic leukemia Neoplasms
C0023467 BXGD001658 Leukemia, Myelocytic, Acute Neoplasms
C0023487 BXGD001669 Acute Promyelocytic Leukemia Neoplasms
C0023530 BXGD001683 Leukopenia Hemic and Lymphatic Diseases
C0023890 BXGD001713 Liver Cirrhosis Pathological Conditions, Signs and Symptoms; Digestive System Diseases
C0023895 BXGD001717 Liver diseases Digestive System Diseases
C0023903 BXGD001720 Liver neoplasms Digestive System Diseases; Neoplasms
C0024115 BXGD001732 Lung diseases Respiratory Tract Diseases
C0024131 BXGD001736 Lupus Vulgaris Infections; Skin and Connective Tissue Diseases
C0024138 BXGD001738 Lupus Erythematosus, Discoid Skin and Connective Tissue Diseases
C0024141 BXGD001740 Lupus Erythematosus, Systemic Skin and Connective Tissue Diseases; Immune System Diseases
C0024623 BXGD001791 Malignant neoplasm of stomach Digestive System Diseases; Neoplasms
C0024776 BXGD001802 Maple Syrup Urine Disease Congenital, Hereditary, and Neonatal Diseases and Abnormalities; Nutritional and Metabolic Diseases; Nervous System Diseases
C0024790 BXGD001804 Paroxysmal nocturnal hemoglobinuria Hemic and Lymphatic Diseases
C0025323 BXGD001864 Menorrhagia Pathological Conditions, Signs and Symptoms; Female Urogenital Diseases and Pregnancy Complications
C0026267 BXGD001896 Mitral Valve Prolapse Syndrome Cardiovascular Diseases
C0026764 BXGD001928 Multiple Myeloma Neoplasms; Immune System Diseases; Hemic and Lymphatic Diseases; Cardiovascular Diseases
C0027022 BXGD001962 Myeloproliferative disease Hemic and Lymphatic Diseases
C0027051 BXGD001963 Myocardial Infarction Pathological Conditions, Signs and Symptoms; Cardiovascular Diseases
C0027497 BXGD001993 Nausea Pathological Conditions, Signs and Symptoms
C0027543 BXGD001997 Avascular necrosis of bone Pathological Conditions, Signs and Symptoms; Musculoskeletal Diseases
C0027627 BXGD002006 Neoplasm Metastasis Pathological Conditions, Signs and Symptoms; Neoplasms
C0027651 BXGD002009 Neoplasms Neoplasms
C0027720 BXGD002028 Nephrosis Female Urogenital Diseases and Pregnancy Complications; Male Urogenital Diseases
C0027726 BXGD002030 Nephrotic Syndrome Female Urogenital Diseases and Pregnancy Complications; Male Urogenital Diseases
C0027746 BXGD002032 Nerve Degeneration Pathological Conditions, Signs and Symptoms
C0027809 BXGD002040 Neurilemmoma Neoplasms
C0027947 BXGD002061 Neutropenia Hemic and Lymphatic Diseases
C0028259 BXGD002073 Nodule
C0028754 BXGD002082 Obesity Pathological Conditions, Signs and Symptoms; Nutritional and Metabolic Diseases
C0030312 BXGD002207 Pancytopenia Hemic and Lymphatic Diseases
C0030524 BXGD002236 Paratuberculosis Infections; Animal Diseases
C0030567 BXGD002240 Parkinson Disease Nervous System Diseases
C0030920 BXGD002263 Peptic Ulcer Digestive System Diseases
C0031036 BXGD002273 Polyarteritis Nodosa Skin and Connective Tissue Diseases; Cardiovascular Diseases
C0032285 BXGD002344 Pneumonia Infections; Respiratory Tract Diseases
C0032320 BXGD002350 Pneumoperitoneum Digestive System Diseases
C0032460 BXGD002355 Polycystic Ovary Syndrome Neoplasms; Female Urogenital Diseases and Pregnancy Complications; Endocrine System Diseases
C0032463 BXGD002357 Polycythemia Vera Neoplasms; Hemic and Lymphatic Diseases
C0032797 BXGD002373 Postpartum Hemorrhage Pathological Conditions, Signs and Symptoms; Female Urogenital Diseases and Pregnancy Complications
C0032807 BXGD002375 Postphlebitic Syndrome Cardiovascular Diseases
C0032914 BXGD002379 Pre-Eclampsia Female Urogenital Diseases and Pregnancy Complications
C0032962 BXGD002382 Pregnancy Complications Female Urogenital Diseases and Pregnancy Complications
C0033626 BXGD002412 Protein Deficiency Nutritional and Metabolic Diseases
C0034065 BXGD002454 Pulmonary Embolism Respiratory Tract Diseases; Cardiovascular Diseases
C0034069 BXGD002458 Pulmonary Fibrosis Respiratory Tract Diseases
C0034152 BXGD002467 Henoch-Schoenlein Purpura Pathological Conditions, Signs and Symptoms; Immune System Diseases; Hemic and Lymphatic Diseases; Cardiovascular Diseases
C0034155 BXGD002468 Purpura, Thrombotic Thrombocytopenic Pathological Conditions, Signs and Symptoms; Hemic and Lymphatic Diseases
C0034341 BXGD002476 Pyruvate Carboxylase Deficiency Disease Congenital, Hereditary, and Neonatal Diseases and Abnormalities; Nutritional and Metabolic Diseases; Nervous System Diseases
C0034362 BXGD002479 Q Fever Infections
C0035126 BXGD002509 Reperfusion Injury Pathological Conditions, Signs and Symptoms; Cardiovascular Diseases
C0035222 BXGD002513 Respiratory Distress Syndrome, Adult Respiratory Tract Diseases
C0035302 BXGD002527 Retinal Artery Occlusion Eye Diseases; Cardiovascular Diseases
C0035328 BXGD002537 Retinal Vein Occlusion Eye Diseases; Cardiovascular Diseases
C0035344 BXGD002541 Retinopathy of Prematurity Congenital, Hereditary, and Neonatal Diseases and Abnormalities; Eye Diseases
C0036341 BXGD002600 Schizophrenia Mental Disorders
C0036472 BXGD002618 Scrub Typhus Infections
C0036572 BXGD002625 Seizures Pathological Conditions, Signs and Symptoms; Nervous System Diseases
C0036690 BXGD002632 Septicemia Pathological Conditions, Signs and Symptoms; Infections
C0036982 BXGD002651 Shock, Hemorrhagic Pathological Conditions, Signs and Symptoms
C0037054 BXGD002663 Sickle Cell Trait Congenital, Hereditary, and Neonatal Diseases and Abnormalities; Hemic and Lymphatic Diseases
C0037198 BXGD002670 Sinus Thrombosis, Intracranial Nervous System Diseases; Cardiovascular Diseases
C0037284 BXGD002679 Skin lesion Skin and Connective Tissue Diseases
C0038454 BXGD002760 Cerebrovascular accident Nervous System Diseases; Cardiovascular Diseases
C0038525 BXGD002768 Subarachnoid Hemorrhage Pathological Conditions, Signs and Symptoms; Nervous System Diseases; Cardiovascular Diseases
C0039101 BXGD002790 synovial sarcoma Neoplasms
C0039128 BXGD002794 Syphilis Female Urogenital Diseases and Pregnancy Complications; Infections; Male Urogenital Diseases
C0039585 BXGD002821 Androgen-Insensitivity Syndrome Congenital, Hereditary, and Neonatal Diseases and Abnormalities; Female Urogenital Diseases and Pregnancy Complications; Male Urogenital Diseases; Endocrine System Diseases
C0039685 BXGD002825 Tetralogy of Fallot Congenital, Hereditary, and Neonatal Diseases and Abnormalities; Cardiovascular Diseases
C0039730 BXGD002826 Thalassemia Congenital, Hereditary, and Neonatal Diseases and Abnormalities; Hemic and Lymphatic Diseases
C0040021 BXGD002834 Thromboangiitis Obliterans Cardiovascular Diseases
C0040028 BXGD002835 Thrombocythemia, Essential Hemic and Lymphatic Diseases
C0040034 BXGD002836 Thrombocytopenia Hemic and Lymphatic Diseases
C0040038 BXGD002837 Thromboembolism Cardiovascular Diseases
C0040053 BXGD002839 Thrombosis Cardiovascular Diseases
C0040420 BXGD002861 Tonometry
C0041296 BXGD002903 Tuberculosis Infections
C0041912 BXGD002937 Upper Respiratory Infections Infections; Respiratory Tract Diseases
C0042075 BXGD002955 Urologic Diseases Female Urogenital Diseases and Pregnancy Complications; Male Urogenital Diseases
C0042345 BXGD002977 Varicosity Cardiovascular Diseases
C0042373 BXGD002978 Vascular Diseases Cardiovascular Diseases
C0042487 BXGD002986 Venous Thrombosis Cardiovascular Diseases
C0042769 BXGD002999 Virus Diseases Infections
C0042880 BXGD003011 Vitamin K Deficiency Nutritional and Metabolic Diseases; Hemic and Lymphatic Diseases
C0042974 BXGD003019 von Willebrand Disease Congenital, Hereditary, and Neonatal Diseases and Abnormalities; Hemic and Lymphatic Diseases
C0079102 BXGD003062 Cerebral Thrombosis Nervous System Diseases; Cardiovascular Diseases
C0085077 BXGD003117 Sweet Syndrome Skin and Connective Tissue Diseases
C0085083 BXGD003120 Ovarian Hyperstimulation Syndrome Female Urogenital Diseases and Pregnancy Complications; Endocrine System Diseases
C0085096 BXGD003123 Peripheral Vascular Diseases Cardiovascular Diseases
C0085220 BXGD003142 Cerebral Amyloid Angiopathy Nutritional and Metabolic Diseases; Nervous System Diseases; Cardiovascular Diseases
C0085278 BXGD003150 Antiphospholipid Syndrome Immune System Diseases
C0085293 BXGD003154 Hepatitis E Digestive System Diseases; Infections
C0085409 BXGD003168 Polyendocrinopathies, Autoimmune Immune System Diseases; Endocrine System Diseases
C0085584 BXGD003195 Encephalopathies Nervous System Diseases
C0085605 BXGD003200 Liver Failure Digestive System Diseases
C0085650 BXGD003223 Purpura Fulminans Pathological Conditions, Signs and Symptoms; Hemic and Lymphatic Diseases
C0085669 BXGD003233 Acute leukemia Pathological Conditions, Signs and Symptoms; Neoplasms
C0085762 BXGD003251 Alcohol abuse Chemically-Induced Disorders; Mental Disorders
C0086981 BXGD003317 Sicca Syndrome Eye Diseases; Skin and Connective Tissue Diseases; Musculoskeletal Diseases; Immune System Diseases; Stomatognathic Diseases
C0087086 BXGD003320 Thrombus Cardiovascular Diseases
C0149793 BXGD003366 Amaurosis Fugax Pathological Conditions, Signs and Symptoms; Eye Diseases; Nervous System Diseases
C0149871 BXGD003375 Deep Vein Thrombosis Cardiovascular Diseases
C0149931 BXGD003388 Migraine Disorders Nervous System Diseases
C0151445 BXGD003418 Primary Raynaud Phenomenon Cardiovascular Diseases
C0151517 BXGD003431 Complete atrioventricular block Pathological Conditions, Signs and Symptoms; Cardiovascular Diseases
C0151529 BXGD003433 Prolonged bleeding time
C0151699 BXGD003461 Intracranial Hemorrhage Pathological Conditions, Signs and Symptoms; Nervous System Diseases; Cardiovascular Diseases
C0151744 BXGD003469 Myocardial Ischemia Cardiovascular Diseases
C0151747 BXGD003471 Renal tubular disorder Female Urogenital Diseases and Pregnancy Complications; Male Urogenital Diseases
C0151872 BXGD003493 Prothrombin time increased Hemic and Lymphatic Diseases
C0151945 BXGD003508 Thrombosis of cerebral veins Nervous System Diseases; Cardiovascular Diseases
C0153381 BXGD003626 Malignant neoplasm of mouth Neoplasms; Stomatognathic Diseases
C0154841 BXGD003749 Central retinal vein occlusion Eye Diseases; Nervous System Diseases; Cardiovascular Diseases
C0155626 BXGD003806 Acute myocardial infarction Pathological Conditions, Signs and Symptoms; Cardiovascular Diseases
C0155773 BXGD003820 Portal Vein Thrombosis Cardiovascular Diseases
C0155789 BXGD003822 Bleeding esophageal varices Pathological Conditions, Signs and Symptoms; Digestive System Diseases
C0162557 BXGD003956 Liver Failure, Acute Digestive System Diseases
C0162739 BXGD003979 HELLP Syndrome Female Urogenital Diseases and Pregnancy Complications
C0162819 BXGD003984 Skin Diseases, Vascular Skin and Connective Tissue Diseases
C0206624 BXGD004190 Hepatoblastoma Neoplasms
C0206698 BXGD004248 Cholangiocarcinoma Neoplasms
C0220641 BXGD004305 Lip and Oral Cavity Carcinoma Neoplasms; Stomatognathic Diseases
C0221505 BXGD004466 Lesion of brain
C0232726 BXGD004560 Rectal tenesmus Digestive System Diseases; Nervous System Diseases
C0235430 BXGD004746 Ketonemia Nutritional and Metabolic Diseases
C0235522 BXGD004752 Disorder of vein Pathological Conditions, Signs and Symptoms; Cardiovascular Diseases
C0235574 BXGD004754 Intravascular hemolysis Pathological Conditions, Signs and Symptoms
C0235974 BXGD004796 Pancreatic carcinoma Digestive System Diseases; Neoplasms; Endocrine System Diseases
C0238096 BXGD004873 Embolism, Paradoxical Cardiovascular Diseases
C0239937 BXGD005008 Microscopic hematuria Pathological Conditions, Signs and Symptoms; Female Urogenital Diseases and Pregnancy Complications; Male Urogenital Diseases
C0239946 BXGD005010 Fibrosis, Liver Pathological Conditions, Signs and Symptoms; Digestive System Diseases
C0240412 BXGD005034 Muscle hematoma Pathological Conditions, Signs and Symptoms
C0240671 BXGD005048 Partial thromboplastin time increased (finding)
C0240912 BXGD005062 Vertical Talus Congenital, Hereditary, and Neonatal Diseases and Abnormalities; Musculoskeletal Diseases
C0242339 BXGD005150 Dyslipidemias Nutritional and Metabolic Diseases
C0242342 BXGD005152 Sheehan Syndrome Nervous System Diseases; Endocrine System Diseases
C0242383 BXGD005160 Age related macular degeneration Eye Diseases
C0242488 BXGD005170 Acute Lung Injury Respiratory Tract Diseases
C0242666 BXGD005185 Protein S Deficiency Hemic and Lymphatic Diseases
C0242852 BXGD005197 Proliferative vitreoretinopathy Eye Diseases
C0242966 BXGD005201 Systemic Inflammatory Response Syndrome Pathological Conditions, Signs and Symptoms
C0243026 BXGD005210 Sepsis Pathological Conditions, Signs and Symptoms; Infections
C0243038 BXGD005211 Carcinoma, Lewis Lung Neoplasms
C0243066 BXGD005213 Atresia
C0259744 BXGD005215 dysproteinemia Hemic and Lymphatic Diseases
C0265099 BXGD005453 Basilar artery thrombosis Nervous System Diseases; Cardiovascular Diseases
C0265706 BXGD005570 Gastroschisis Pathological Conditions, Signs and Symptoms; Congenital, Hereditary, and Neonatal Diseases and Abnormalities; Musculoskeletal Diseases
C0267406 BXGD005746 Mesenteric infarction Digestive System Diseases; Skin and Connective Tissue Diseases
C0267412 BXGD005747 Mesenteric Venous Thrombosis Digestive System Diseases; Cardiovascular Diseases
C0267797 BXGD005777 Acute hepatitis Digestive System Diseases
C0268615 BXGD006009 5,10-Methylenetetrahydrofolate reductase deficiency Nutritional and Metabolic Diseases
C0270853 BXGD006119 Juvenile Myoclonic Epilepsy Nervous System Diseases
C0271055 BXGD006154 Rhegmatogenous retinal detachment Eye Diseases
C0272285 BXGD006336 Heparin-induced thrombocytopenia Hemic and Lymphatic Diseases
C0272315 BXGD006341 Coagulation factor deficiency syndrome Hemic and Lymphatic Diseases
C0272317 BXGD006342 Hereditary factor II deficiency disease Congenital, Hereditary, and Neonatal Diseases and Abnormalities; Hemic and Lymphatic Diseases
C0272322 BXGD006343 Severe hereditary factor VIII deficiency disease Congenital, Hereditary, and Neonatal Diseases and Abnormalities; Hemic and Lymphatic Diseases
C0272325 BXGD006346 Factor 8 deficiency, acquired Congenital, Hereditary, and Neonatal Diseases and Abnormalities; Hemic and Lymphatic Diseases
C0272350 BXGD006354 Dysfibrinogenemia, Congenital Congenital, Hereditary, and Neonatal Diseases and Abnormalities; Hemic and Lymphatic Diseases
C0272375 BXGD006359 Antithrombin III Deficiency Congenital, Hereditary, and Neonatal Diseases and Abnormalities; Hemic and Lymphatic Diseases
C0276434 BXGD006424 Acute type A viral hepatitis Digestive System Diseases; Infections
C0276496 BXGD006426 Familial Alzheimer Disease (FAD) Nervous System Diseases; Mental Disorders
C0276622 BXGD006432 Acute viral hepatitis
C0278134 BXGD006498 Absence of sensation Pathological Conditions, Signs and Symptoms; Nervous System Diseases
C0278878 BXGD006609 Adult Glioblastoma Neoplasms
C0279606 BXGD006647 Childhood Hepatocellular Carcinoma Digestive System Diseases; Neoplasms
C0279607 BXGD006648 Adult Hepatocellular Carcinoma Digestive System Diseases; Neoplasms
C0279702 BXGD006685 Conventional (Clear Cell) Renal Cell Carcinoma Neoplasms; Female Urogenital Diseases and Pregnancy Complications; Male Urogenital Diseases
C0280474 BXGD006748 Childhood Glioblastoma Neoplasms
C0302809 BXGD006852 Fulminant hepatitis Digestive System Diseases
C0311370 BXGD006882 Lupus anticoagulant disorder Pathological Conditions, Signs and Symptoms; Immune System Diseases; Hemic and Lymphatic Diseases
C0332853 BXGD006901 Anastomosis
C0333516 BXGD006957 Tumor necrosis Pathological Conditions, Signs and Symptoms
C0338106 BXGD007167 Adenocarcinoma of colon Digestive System Diseases; Neoplasms
C0338507 BXGD007195 Non-arteritic ischemic optic neuropathy Eye Diseases; Nervous System Diseases; Cardiovascular Diseases
C0338573 BXGD007199 Cerebral venous sinus thrombosis Nervous System Diseases; Cardiovascular Diseases
C0339505 BXGD007255 Venous retinal branch occlusion Eye Diseases; Cardiovascular Diseases
C0341439 BXGD007408 Chronic liver disease Digestive System Diseases
C0342649 BXGD007522 Vascular calcification Nutritional and Metabolic Diseases
C0344724 BXGD007701 Ostium secundum atrial septal defect Congenital, Hereditary, and Neonatal Diseases and Abnormalities; Cardiovascular Diseases
C0345904 BXGD007745 Malignant neoplasm of liver Digestive System Diseases; Neoplasms
C0376618 BXGD008003 Endotoxemia Pathological Conditions, Signs and Symptoms; Infections
C0392525 BXGD008052 Nephrolithiasis Female Urogenital Diseases and Pregnancy Complications; Male Urogenital Diseases
C0392885 BXGD008071 High density lipoprotein measurement
C0398623 BXGD008202 Thrombophilia Hemic and Lymphatic Diseases
C0398625 BXGD008203 Protein C Deficiency Congenital, Hereditary, and Neonatal Diseases and Abnormalities; Hemic and Lymphatic Diseases
C0400966 BXGD008266 Non-alcoholic Fatty Liver Disease Digestive System Diseases
C0409974 BXGD008401 Lupus Erythematosus Pathological Conditions, Signs and Symptoms; Skin and Connective Tissue Diseases; Immune System Diseases
C0409980 BXGD008403 Primary antiphospholipid syndrome Immune System Diseases
C0423798 BXGD008510 Increased tendency to bruise Wounds and Injuries
C0428472 BXGD008630 Serum HDL cholesterol measurement
C0432474 BXGD008793 Klinefelter's syndrome - male with more than two X chromosomes Congenital, Hereditary, and Neonatal Diseases and Abnormalities; Female Urogenital Diseases and Pregnancy Complications; Male Urogenital Diseases; Endocrine System Diseases
C0494463 BXGD009029 Alzheimer Disease, Late Onset Nervous System Diseases; Mental Disorders
C0497156 BXGD009053 Lymphadenopathy Hemic and Lymphatic Diseases
C0521158 BXGD009130 Recurrent tumor
C0524620 BXGD009236 Metabolic Syndrome X Nutritional and Metabolic Diseases
C0524702 BXGD009242 Pulmonary Thromboembolisms Respiratory Tract Diseases; Cardiovascular Diseases
C0524909 BXGD009247 Hepatitis B, Chronic Digestive System Diseases; Infections
C0543822 BXGD009296 Atherosclerotic occlusive disease Cardiovascular Diseases
C0546126 BXGD009328 Acute Confusional Senile Dementia Nervous System Diseases; Mental Disorders
C0553681 BXGD009406 Hypofibrinogenemia
C0555198 BXGD009432 Malignant Glioma Neoplasms
C0578870 BXGD009553 Chronic idiopathic urticaria Skin and Connective Tissue Diseases; Immune System Diseases
C0584960 BXGD009579 Factor V Leiden mutation Congenital, Hereditary, and Neonatal Diseases and Abnormalities; Hemic and Lymphatic Diseases
C0584983 BXGD009580 Homozygous Factor V Leiden mutation
C0584984 BXGD009581 Heterozygous Factor V Leiden mutation
C0596263 BXGD009639 Carcinogenesis Pathological Conditions, Signs and Symptoms; Neoplasms
C0598608 BXGD009668 Hyperhomocysteinemia Congenital, Hereditary, and Neonatal Diseases and Abnormalities; Nutritional and Metabolic Diseases
C0600433 BXGD009707 Activated Protein C Resistance Congenital, Hereditary, and Neonatal Diseases and Abnormalities; Hemic and Lymphatic Diseases
C0677898 BXGD009735 invasive cancer Neoplasms
C0677932 BXGD009736 Progressive Neoplastic Disease
C0678222 BXGD009749 Breast Carcinoma Neoplasms; Skin and Connective Tissue Diseases
C0683381 BXGD009787 inflammatory joint disease
C0684275 BXGD009792 Hemophilia, NOS Congenital, Hereditary, and Neonatal Diseases and Abnormalities; Hemic and Lymphatic Diseases
C0685938 BXGD009829 Malignant neoplasm of gastrointestinal tract Digestive System Diseases; Neoplasms
C0686619 BXGD009835 Secondary malignant neoplasm of lymph node Pathological Conditions, Signs and Symptoms; Neoplasms
C0699791 BXGD009867 Stomach Carcinoma Digestive System Diseases; Neoplasms
C0745497 BXGD010128 Thrombosis of internal jugular vein Cardiovascular Diseases
C0745744 BXGD010133 End Stage Liver Disease Digestive System Diseases
C0746102 BXGD010136 Chronic lung disease Respiratory Tract Diseases
C0749087 BXGD010208 Thrombosis of subclavian vein Respiratory Tract Diseases; Cardiovascular Diseases
C0750900 BXGD010241 Alzheimer's Disease, Focal Onset Nervous System Diseases; Mental Disorders
C0750901 BXGD010242 Alzheimer Disease, Early Onset Nervous System Diseases; Mental Disorders
C0751010 BXGD010289 Cerebral Infarction, Left Hemisphere Pathological Conditions, Signs and Symptoms; Nervous System Diseases; Cardiovascular Diseases
C0751011 BXGD010290 Cerebral Infarction, Right Hemisphere Pathological Conditions, Signs and Symptoms; Nervous System Diseases; Cardiovascular Diseases
C0751012 BXGD010291 Anterior Choroidal Artery Infarction Pathological Conditions, Signs and Symptoms; Nervous System Diseases; Cardiovascular Diseases
C0751014 BXGD010292 Subcortical Infarction Pathological Conditions, Signs and Symptoms; Nervous System Diseases; Cardiovascular Diseases
C0751202 BXGD010347 Cystathionine beta-Synthase Deficiency Disease Congenital, Hereditary, and Neonatal Diseases and Abnormalities; Nutritional and Metabolic Diseases; Skin and Connective Tissue Diseases; Nervous System Diseases
C0751500 BXGD010475 Petrous Sinus Thrombophlebitis Nervous System Diseases; Cardiovascular Diseases
C0751501 BXGD010476 Intracranial Sinus Thrombophlebitis Nervous System Diseases; Cardiovascular Diseases
C0751502 BXGD010477 Petrous Sinus Thrombosis Nervous System Diseases; Cardiovascular Diseases
C0751569 BXGD010504 Genitourinary Cancer Neoplasms; Female Urogenital Diseases and Pregnancy Complications; Male Urogenital Diseases
C0751606 BXGD010523 Adult Acute Lymphocytic Leukemia
C0751956 BXGD010653 Acute Cerebrovascular Accidents Nervous System Diseases; Cardiovascular Diseases
C0752155 BXGD010679 Central Nervous System Vascular Malformations Congenital, Hereditary, and Neonatal Diseases and Abnormalities; Nervous System Diseases; Cardiovascular Diseases
C0795687 BXGD010726 Cerebral arterial thrombosis Nervous System Diseases; Cardiovascular Diseases
C0836924 BXGD010864 Thrombocytosis Hemic and Lymphatic Diseases
C0852036 BXGD010934 Pregnancy associated hypertension Female Urogenital Diseases and Pregnancy Complications; Cardiovascular Diseases
C0852077 BXGD010935 Blood Coagulation Disorders, Inherited Congenital, Hereditary, and Neonatal Diseases and Abnormalities; Hemic and Lymphatic Diseases
C0852879 BXGD010955 Pulmonary Alveolar Hemorrhage
C0852949 BXGD010957 Arteriopathic disease Pathological Conditions, Signs and Symptoms; Cardiovascular Diseases
C0856761 BXGD011115 Budd-Chiari Syndrome Digestive System Diseases; Cardiovascular Diseases
C0887799 BXGD011396 Posterior Choroidal Artery Infarction Pathological Conditions, Signs and Symptoms; Nervous System Diseases; Cardiovascular Diseases
C0917798 BXGD011409 Cerebral Ischemia Nervous System Diseases; Cardiovascular Diseases
C0917805 BXGD011414 Transient Cerebral Ischemia Nervous System Diseases; Cardiovascular Diseases
C0919631 BXGD011431 Upper Extremity Deep Vein Thrombosis, Primary Cardiovascular Diseases
C0919747 BXGD011439 Cytokine storm
C0948008 BXGD011499 Ischemic stroke Nervous System Diseases; Cardiovascular Diseases
C0948089 BXGD011504 Acute Coronary Syndrome Cardiovascular Diseases
C0948441 BXGD011538 Venoocclusive disease Cardiovascular Diseases
C0949083 BXGD011569 Hospital acquired pneumonia Pathological Conditions, Signs and Symptoms; Infections; Respiratory Tract Diseases
C1096116 BXGD011603 Acquired haemophilia
C1142442 BXGD011755 Intrahepatic biloma
C1168401 BXGD011792 Squamous cell carcinoma of the head and neck Neoplasms
C1260403 BXGD011832 prothrombin gene mutation Hemic and Lymphatic Diseases
C1260903 BXGD011842 Dysfibrinogenemia Congenital, Hereditary, and Neonatal Diseases and Abnormalities; Hemic and Lymphatic Diseases
C1269955 BXGD012005 Tumor Cell Invasion
C1273976 BXGD012020 First myocardial infarction Pathological Conditions, Signs and Symptoms; Cardiovascular Diseases
C1292778 BXGD012237 Chronic myeloproliferative disorder Neoplasms; Hemic and Lymphatic Diseases
C1306459 BXGD012361 Primary malignant neoplasm Neoplasms
C1306759 BXGD012374 Eosinophilic disorder Hemic and Lymphatic Diseases
C1306889 BXGD012380 Peripheral arterial occlusive disease Cardiovascular Diseases
C1318485 BXGD012394 Liver regeneration disorder Digestive System Diseases
C1333177 BXGD012605 Lymphoproliferative Disorder of the Skin Skin and Connective Tissue Diseases; Immune System Diseases; Hemic and Lymphatic Diseases
C1333977 BXGD012663 Hepatitis B Virus-Related Hepatocellular Carcinoma
C1412000 BXGD013049 Mesenteric vascular insufficiency Digestive System Diseases; Cardiovascular Diseases
C1455728 BXGD013105 Acute fatty liver of pregnancy Digestive System Diseases; Female Urogenital Diseases and Pregnancy Complications
C1456418 BXGD013117 Absence of muscle
C1519670 BXGD013241 Tumor Angiogenesis Pathological Conditions, Signs and Symptoms
C1527311 BXGD013268 Brain Edema Nervous System Diseases
C1536220 BXGD013341 ST segment elevation myocardial infarction Pathological Conditions, Signs and Symptoms; Cardiovascular Diseases
C1541923 BXGD013355 Infective endocarditis Cardiovascular Diseases
C1560249 BXGD013361 Adverse Event Associated with Cardiac Arrhythmia
C1561643 BXGD013363 Chronic Kidney Diseases Female Urogenital Diseases and Pregnancy Complications; Male Urogenital Diseases
C1565489 BXGD013401 Renal Insufficiency Female Urogenital Diseases and Pregnancy Complications; Male Urogenital Diseases
C1611743 BXGD013456 Familial (FPAH)
C1621958 BXGD013468 Glioblastoma Multiforme Neoplasms
C1623038 BXGD013475 Cirrhosis Pathological Conditions, Signs and Symptoms
C1632842 BXGD013481 Complicated appendicitis Digestive System Diseases; Infections
C1704436 BXGD013564 Peripheral Arterial Diseases Cardiovascular Diseases
C1709735 BXGD013631 Prosthetic Valve Thrombosis Cardiovascular Diseases
C1719672 BXGD013659 Severe Sepsis Pathological Conditions, Signs and Symptoms; Infections
C1739406 BXGD013741 Acute coagulopathy
C1833683 BXGD013938 NEPHROLITHIASIS, CALCIUM OXALATE Female Urogenital Diseases and Pregnancy Complications; Male Urogenital Diseases
C1837352 BXGD014223 Childhood onset
C1842937 BXGD014546 AURAL ATRESIA, CONGENITAL Congenital, Hereditary, and Neonatal Diseases and Abnormalities
C1852242 BXGD015266 Nonarteritic anterior ischemic optic neuropathy (NAION)
C1856857 BXGD015646 STROKE, ISCHEMIC, SUSCEPTIBILITY TO
C1857276 BXGD015688 Trichohepatoenteric Syndrome Pathological Conditions, Signs and Symptoms; Congenital, Hereditary, and Neonatal Diseases and Abnormalities; Female Urogenital Diseases and Pregnancy Complications; Skin and Connective Tissue Diseases
C1859592 BXGD015912 ATRICHIA WITH PAPULAR LESIONS Pathological Conditions, Signs and Symptoms; Skin and Connective Tissue Diseases
C1861172 BXGD016016 Venous Thromboembolism Cardiovascular Diseases
C1861403 BXGD016045 Variable expressivity
C1867596 BXGD016466 Hyperprothrombinemia Hemic and Lymphatic Diseases
C1867743 BXGD016470 Premature coronary artery atherosclerosis Cardiovascular Diseases
C1956346 BXGD016627 Coronary Artery Disease Cardiovascular Diseases
C1959635 BXGD016646 Parvovirus B19 (disease)
C1961102 BXGD016673 Precursor Cell Lymphoblastic Leukemia Lymphoma Neoplasms; Immune System Diseases; Hemic and Lymphatic Diseases
C1963943 BXGD016706 Atherothrombosis
C1969572 BXGD016781 Prolonged bleeding after dental extraction
C2237512 BXGD016961 cephalohematoma
C2239176 BXGD016965 Liver carcinoma Digestive System Diseases; Neoplasms
C2314994 BXGD017020 Infarction of spinal cord Nervous System Diseases; Cardiovascular Diseases; Wounds and Injuries
C2316810 BXGD017030 Chronic kidney disease stage 5 Female Urogenital Diseases and Pregnancy Complications; Male Urogenital Diseases
C2363755 BXGD017103 Acquired Protein S Deficiency Hemic and Lymphatic Diseases
C2363915 BXGD017115 Cerebellar ischaemia
C2584409 BXGD017126 Prothrombin G20210A mutation Hemic and Lymphatic Diseases
C2584620 BXGD017129 Thrombophilia, hereditary Hemic and Lymphatic Diseases
C2585317 BXGD017135 Acquired thrombophilia Hemic and Lymphatic Diseases
C2585350 BXGD017136 Hereditary hyperhomocysteinemia Congenital, Hereditary, and Neonatal Diseases and Abnormalities; Nutritional and Metabolic Diseases; Hemic and Lymphatic Diseases
C2608079 BXGD017154 WARFARIN SENSITIVITY (disorder) Congenital, Hereditary, and Neonatal Diseases and Abnormalities; Nutritional and Metabolic Diseases
C2609046 BXGD017161 Sticky platelet syndrome Congenital, Hereditary, and Neonatal Diseases and Abnormalities; Hemic and Lymphatic Diseases
C2711227 BXGD017478 Steatohepatitis Digestive System Diseases
C2717961 BXGD017519 Thrombotic Microangiopathies Hemic and Lymphatic Diseases
C2721734 BXGD017549 Methylenetetrahydrofolate reductase polymorphism Hemic and Lymphatic Diseases
C2830004 BXGD017804 Somnolence Pathological Conditions, Signs and Symptoms
C2931822 BXGD018068 Nasopharyngeal carcinoma Neoplasms; Stomatognathic Diseases; Otorhinolaryngologic Diseases
C2939419 BXGD018178 Secondary Neoplasm Pathological Conditions, Signs and Symptoms; Neoplasms
C2939465 BXGD018182 Deficiency of glucose-6-phosphate dehydrogenase Congenital, Hereditary, and Neonatal Diseases and Abnormalities; Nutritional and Metabolic Diseases; Hemic and Lymphatic Diseases
C2945695 BXGD018187 Limb ischemia
C2985280 BXGD018223 Blood Protein Measurement
C3160733 BXGD018471 THROMBOPHILIA DUE TO THROMBIN DEFECT
C3160844 BXGD018482 PAI-1 polymorphism
C3203102 BXGD018555 Idiopathic pulmonary arterial hypertension Respiratory Tract Diseases
C3203356 BXGD018556 Factor II deficiency Hemic and Lymphatic Diseases
C3241937 BXGD018578 Nonalcoholic Steatohepatitis Digestive System Diseases
C3273019 BXGD018642 Early Hepatocellular Carcinoma Digestive System Diseases; Neoplasms
C3279439 BXGD018757 Recurrent spontaneous abortion Female Urogenital Diseases and Pregnancy Complications
C3280672 BXGD018853 PREGNANCY LOSS, RECURRENT, SUSCEPTIBILITY TO, 2
C3489532 BXGD018934 Cone-Rod Dystrophy 2 Congenital, Hereditary, and Neonatal Diseases and Abnormalities; Eye Diseases
C3539781 BXGD019086 Progressive cGVHD
C3550150 BXGD019132 Recurrent thrombophlebitis Cardiovascular Diseases
C3805089 BXGD019460 Hyperfibrinolysis Hemic and Lymphatic Diseases
C3805092 BXGD019461 Methylenetetrahydrofolate reductase gene mutation Congenital, Hereditary, and Neonatal Diseases and Abnormalities; Nutritional and Metabolic Diseases
C3841475 BXGD019800 beta^+^ Thalassemia Congenital, Hereditary, and Neonatal Diseases and Abnormalities; Hemic and Lymphatic Diseases
C3845502 BXGD019809 Myocardial infarction, stroke
C3850141 BXGD019810 Acute-On-Chronic Liver Failure Digestive System Diseases
C3852984 BXGD019815 Acute Mesenteric Arterial Embolus Digestive System Diseases; Cardiovascular Diseases
C3852985 BXGD019816 Occlusive Mesenteric Arterial Ischemia Digestive System Diseases; Cardiovascular Diseases
C3852986 BXGD019817 Nonocclusive Mesenteric Ischemia Digestive System Diseases; Cardiovascular Diseases
C3852987 BXGD019818 Acute Mesenteric Arterial Thrombosis Digestive System Diseases; Cardiovascular Diseases
C3888391 BXGD019969 Nonnuclear polymorphic congenital cataract
C3890031 BXGD020017 prothrombin type 3 phenotype
C3898147 BXGD020064 Neonatal Hypoxic Ischemic Encephalopathy Nervous System Diseases; Cardiovascular Diseases
C4016343 BXGD020312 DYSPROTHROMBINEMIA PROTHROMBIN HIMI-II
C4021097 BXGD020552 Reduced prothrombin activity
C4022608 BXGD020936 Oral cavity bleeding
C4022610 BXGD020937 Excessive bleeding from superficial cuts
C4022611 BXGD020938 Prolonged bleeding following circumcision
C4023145 BXGD021123 Abnormal umbilical stump bleeding
C4048329 BXGD021904 Immunosuppression
C4275242 BXGD022371 Sudden sensorineural hearing loss Pathological Conditions, Signs and Symptoms; Nervous System Diseases; Otorhinolaryngologic Diseases
C4280698 BXGD022385 Reduced prothrombin antigen
C4316812 BXGD022704 Fibrinogen Deficiency Congenital, Hereditary, and Neonatal Diseases and Abnormalities; Hemic and Lymphatic Diseases
C4316906 BXGD022712 Factor XIII deficiency disease
C4321305 BXGD022746 Consumptive Coagulopathy Hemic and Lymphatic Diseases
C4520983 BXGD023052 Congenital atresia of extrahepatic bile duct Congenital, Hereditary, and Neonatal Diseases and Abnormalities; Digestive System Diseases
C4529962 BXGD023178 Fatty Liver Disease
C4551649 BXGD023382 Congenital Dysplasia Of The Hip Congenital, Hereditary, and Neonatal Diseases and Abnormalities; Musculoskeletal Diseases
C4551683 BXGD023389 Adrenal Gland Pheochromocytoma Neoplasms; Endocrine System Diseases
C4552766 BXGD023523 Miscarriage Female Urogenital Diseases and Pregnancy Complications
C4722085 BXGD023788 Malignant neoplasm of colon and/or rectum
C4722227 BXGD023794 Hypoprothrombinemias Congenital, Hereditary, and Neonatal Diseases and Abnormalities; Hemic and Lymphatic Diseases
Target protein-related  compounds
Compounds
BXGC Id Compound Name Strcuture Molecular Weight
BXGC0000368 Gallic acid 170.12
BXGC0000383 (S)-Naringenin 272.25
BXGC0000436 Glycerol 92.09
BXGC0000441 Dimethyl sulfoxide 78.13
BXGC0000689 Squamolone 128.13
BXGC0001233 Oxoxylopine 305.28
BXGC0001767 (E)-Resveratrol 228.25
BXGC0001789 Silibinin 482.44
BXGC0001837 Quercetin 3-rutinoside 610.52
BXGC0001857 Caffeic acid 180.16
BXGC0001868 Catechin 290.27
BXGC0001879 Chlorogenic acid 354.31
BXGC0001889 p-Coumaric acid 164.16
BXGC0001893 Cyanidin 287.24
BXGC0001962 Hesperetin 302.28
BXGC0001965 Hesperidin 610.56
BXGC0002241 Adipostatin A 320.51
BXGC0002586 Calcium 40.08
BXGC0002588 Magnesium 24.31
BXGC0002591 Potassium 39.1
BXGC0002616 Copper 63.55
BXGC0002682 Zinc 65.41
BXGC0002690 alpha-Catechin 290.27
BXGC0002722 Nitrate 62
BXGC0003631 Phytosterol 414.72
BXGC0003705 Chloride 35.45
BXGC0004277 Acetic acid 60.05
BXGC0004730 4-Hydroxyphenylacetic acid 152.15
BXGC0005620 beta-D-Glucopyranose 180.16
BXGC0005624 Genistein 270.24
BXGC0005654 Naringin 580.53
BXGC0005683 Quercetin 302.24
BXGC0005901 Procyanidin B2 578.53
BXGC0006198 Citric acid 192.12
BXGC0006366 trans-Ferulic acid 194.18
BXGC0006368 Formic acid 46.03
BXGC0014807 artabonatine B 311.12
BXGC0017154 4-hydroxyphenylpyruvic acid 180.04
BXGC0018252 Embelin 294.18
BXGC0018397 beta-1,4-mannan 180.06
BXGC0019578 callyspongynic acid 470.28
BXGC0019584 leonuriside 332.11
BXGC0021815 3-methoxy-5-pentyl-phenol 194.13
BXGC0022669 (2S,3R,4S,5S,6R)-3,4,5-trihydroxy-6-(hydroxymethyl)oxan-2-yl (2S,4S,7R,8S,9S,10S,12R,13R,16R,17S,18R)-16-(acetyloxy)-10-hydroxy-2-(hydroxymethyl)-9,13,17-trimethyl-7-(4-methyl-2-oxopent-3-en-1-yl)-6-oxo-5-oxapentacyclo[10.8.0.0^{2,9}.0^{4,8}.0^{13,18}]ico 734.35
BXGC0024199 PRENYLAGARAMIDE B 928.51
BXGC0025237 koaburaside 332.11
BXGC0028823 (2R,3R,4S,5S,6R)-2-[[(1S,2R,3R)-7-Hydroxy-1-(4-Hydroxy-3,5-Dimethoxyphenyl)-3-(Hydroxymethyl)-6,8-Dimethoxy-1,2,3,4-Tetrahydronaphthalen-2-Yl]Methoxy]-6-(Hydroxymethyl)Oxane-3,4,5-Triol 582.23
BXGC0029242 n.a 540.31
BXGC0029259 n.a 626.42
BXGC0029453 5-(8Z-Heptadecenyl)-1,3-Benzenediol 346.29
BXGC0030052 flavinantine 327.15
BXGC0031379 n.a 407.27
BXGC0032020 PRENYLAGARAMIDE A 1080.49
BXGC0032381 Daucosterol 576.44
BXGC0032467 Nostocyclopeptide A2 790.4
BXGC0032490 Nostocyclopeptide A1 756.42
BXGC0033602 uncinine 221.11
BXGC0037531 Cyanin 612.17
BXGC0037687 (4S)-2-methylpentane-2,4-diol 118.1
BXGC0038038 2-Carboxybenzeneacetic Acid 180.04
BXGC0042707 salutaridine 327.15
BXGC0043068 GR 133686 480.29
BXGC0044200 Menadione 172.05
BXGC0044780 Cnicin 378.17
BXGC0045139 (2S,3R,4S,5S,6R)-3,4,5-trihydroxy-6-(hydroxymethyl)oxan-2-yl (2S,4S,7R,8S,9S,10S,12R,13R,16R,17S,18R)-16-(acetyloxy)-2-[(acetyloxy)methyl]-10-hydroxy-9,13,17-trimethyl-7-(4-methyl-2-oxopent-3-en-1-yl)-6-oxo-5-oxapentacyclo[10.8.0.0^{2,9}.0^{4,8}.0^{13,18} 776.36
BXGC0045220 1-[5-(2-Methoxy-4,4-Dihydroxydihydrochalconyl)]-1-(4-Hydroxyphenyl)-3-(2-Methoxy-4-Hydroxyphenyl)Propane 528.21
BXGC0045233 COCHINCHINENENE A 526.24
BXGC0045234 Cochinchinenene C 498.2
BXGC0045235 COCHINCHINENENE D 484.19
BXGC0045237 (2R)-2-(4-Hydroxyphenyl)-6-[1-(4-Hydroxyphenyl)-3-(4-Hydroxy-2-Methoxyphenyl)Propyl]-8-Methylchroman-7-Ol 512.22
BXGC0045238 Cochinchinenin B 542.23
BXGC0045239 COCHINCHINENIN C 542.23
BXGC0045777 Cochinchinenene B 512.22
BXGC0047222 (1S,2R,4aR,4bR,6S,6aS,6bS,7R,9aS,10aR,12aR)-2-Acetoxy-6-hydroxy-1,4a,6a,10a-tetramethyl-7-(4-methyl-2-oxo-pent-3-enyl)-8-oxo-2,3,4,4a,4b,5,6,6a,6b,7,8,9a,10,10a,12,12a-hexadecahydro-1H-9-oxa-pentaleno[2,1-a]phenanthrene-1-carboxylic acid 556.3
BXGC0047287 Rapanone 322.21
BXGC0047867 Dalfampridine 94.05
BXGC0049447 acetate 59.01
BXGC0049646 2,5-Dihydroxyl-3-Undecyl-1,4-Benzoquinone 350.25
BXGC0049748 5-(Heptadeca-8,11-Dienyl)Benzene-1,3-Diol 344.27
BXGC0050194 alpha-D-Mannose 180.06
BXGC0053126 5-{8(Z),Pentadecenyl}Resorcinol 318.26
The  target protein-related  foods
Foods
BXGF Id Food Name Scientific Name Food Group Number of compound? Number of compound in food, higher numbers indicate the food are more associated with the protein