acompound

General Compound Information
BXGC Id	BXGC0017515
Compound Name	(R)-Pinocembrin
Structure
Formula	C15H12O4
InchiKey	URFCJEUYXNAHFI-CYBMUJFWSA-N
SMILES	Oc1cc2O[C@H](CC(=O)c2c(c1)O)c1ccccc1
Inchi	InChI=1S/C15H12O4/c16-10-6-11(17)15-12(18)8-13(19-14(15)7-10)9-4-2-1-3-5-9/h1-7,13,16-17H,8H2/t13-/m1/s1
IUPAC	(2R)-5,7-dihydroxy-2-phenyl-2,3-dihydrochromen-4-one
Molecular Weight	256.07
Pubchem Id	667544
Chembl Id	CHEMBL399249

Targets of Information Source

DrugBank

n.a

Uniport Id	BXGT Id	Protein Name	Status	Protein Class	Gene	Groups	Target Type
Uniport Id	BXGT Id	Protein Name	Status	Protein Class	Gene	Groups	Target Type

PDB

n.a

Uniport Id	BXGT Id	Protein Name	Status	Protein Class	Gene	Ki nM	ic50 nM	Kd nM	Ka M-1
Uniport Id	BXGT Id	Protein Name	Status	Protein Class	Gene	Ki nM	ic50 nM	Kd nM	Ka M-1

Binding DB

Uniport Id	BXGT Id	Protein Name	Status	Protein Class	Gene	Ki nM	ic50 nM	Kd nM	EC50 nM
Uniport Id	BXGT Id	Protein Name	Status	Protein Class	Gene	Ki nM	ic50 nM	Kd nM	EC50 nM
reviewed	BXGT007685	Serine/threonine-protein kinase pim-1	reviewed	Kinase	PIM1	-	60200	-	-
reviewed	BXGT007685	Serine/threonine-protein kinase pim-1	reviewed	Kinase	PIM1	-	60256	-	-

CHEMBL

Uniport Id	BXGT Id	Protein Name	Status	Protein Class	Gene	width="10%">Type	Relation	value	Units
Uniport Id	BXGT Id	Protein Name	Status	Protein Class	Gene	Type	Relation	value	Units
Q03164	BXGT012700	Histone-lysine N-methyltransferase 2A	reviewed	-	KMT2A	Potency	'='	39810	nM
O00255	BXGT003903	Menin	reviewed	-	MEN1	Potency	'='	39810	nM
Q99714	BXGT019954	3-hydroxyacyl-CoA dehydrogenase type-2	reviewed	Enzyme	HSD17B10	Potency	'='	25118	nM
P11712	BXGT007738	Cytochrome P450 2C9	reviewed	-	CYP2C9	Potency	'='	12589	nM
P33261	BXGT009707	Cytochrome P450 2C19	reviewed	-	CYP2C19	Potency	'='	631	nM
P11309	BXGT007685	Serine/threonine-protein kinase pim-1	reviewed	Kinase	PIM1	#NAME?	'='	-1	uM
P10635	BXGT007595	Cytochrome P450 2D6	reviewed	-	CYP2D6	Potency	'='	19952	nM
P15917	BXGT008169	Lethal factor	reviewed	-	lef	Potency	'='	12589	nM
P08684	BXGT006812	Cytochrome P450 3A4	reviewed	Enzyme	CYP3A4	Potency	'='	12589	nM
P10636	BXGT007596	Microtubule-associated protein tau	reviewed	-	MAPT	Potency	'='	19952	nM

Foods containing the compound

Foods

BXGF Id	Food Name	Scientific Name	Food Group
BXGF Id	Food Name	Scientific Name	Food Group
BXGF00139	Pepper (Spice)	Piper nigrum	Herbs and Spices
BXGF00151	Pomegranate	Punica granatum	Fruits
BXGF01721	Humulus lupulus	Humulus lupulus	Medicinal Plant
BXGF02176	Pseudotsuga sinensis var. wilsoniana	Pseudotsuga sinensis var. wilsoniana	Others
BXGF02213	Glycyrrhiza sp.	Glycyrrhiza sp.	Others
BXGF02381	Glycyrrhiza inflata	Glycyrrhiza inflata	Medicinal Plant
BXGF02626	Dalbergia odorifera	Dalbergia odorifera	Medicinal Plant
BXGF02833	Polygonatum zanlanscianense	Polygonatum zanlanscianense	Medicinal Plant
BXGF02896	Maprounea guianensis	Maprounea guianensis	Others
BXGF03189	Rhododendron dauricum	Rhododendron dauricum	Medicinal Plant
BXGF03235	Syzygium samarangense	Syzygium samarangense	Medicinal Plant
BXGF03967	Helichrysum italicum	Helichrysum italicum	Medicinal Plant
BXGF04200	Euphorbia hirta	Euphorbia hirta	Medicinal Plant
BXGF04451	Pteris cretica var. nervosa	Pteris cretica var. nervosa	Garden Plant
BXGF04691	Oroxylum indicum	Oroxylum indicum	Medicinal Plant
BXGF04872	Glycyrrhiza glabra	Glycyrrhiza glabra	Medicinal Plant
BXGF05476	Broussonetia papyrifera	Broussonetia papyrifera	Medicinal Plant
BXGF05790	Glycyrrhiza uralensis	Glycyrrhiza uralensis	Medicinal Plant
BXGF05923	Peritassa campestris	Peritassa campestris	Human Edible Plant
BXGF05946	Gypsophila licentiana hand.-mazz.	Gypsophila licentiana hand.-mazz.	Others
BXGF05958	Lepechinia caulescens	Lepechinia caulescens	Medicinal Plant

The compound-realted diseases

Diseases

BXGD Id	Disease Name	CUI Disease Id	Disease Class Name	Number of targets^{?Number of targets related to compound connecting disease, higher numbers indicate the compound is more associated with the disease}