Showing entry for (2S,3S,4R)-2-Hydroxymethylpiperidine-3,4-Diol


　 　 　 　 　 　 　 　 　 　 　 　 　 　 　
General Compound Information
BXGC IdBXGC0018345
Compound Name(2S,3S,4R)-2-Hydroxymethylpiperidine-3,4-Diol
Structure
FormulaC6H13NO3
InchiKeyYZNNBIPIQWYLDM-JKUQZMGJSA-N
SMILESOC[C@@H]1NCC[C@H]([C@H]1O)O
InchiInChI=1S/C6H13NO3/c8-3-4-6(10)5(9)1-2-7-4/h4-10H,1-3H2/t4-,5+,6-/m0/s1
IUPAC(2S,3S,4R)-2-(hydroxymethyl)piperidine-3,4-diol
Molecular Weight147.09
Pubchem Id11389465
Chembl IdCHEMBL1818436
Targets of Information Source
DrugBank n.a
Uniport Id BXGT Id Protein Name Status Protein Class Gene Groups Target Type
Uniport Id BXGT Id Protein Name Status Protein Class Gene Groups Target Type
PDB n.a
Uniport Id BXGT Id Protein Name Status Protein Class Gene Ki nM ic50 nM Kd nM Ka M-1
Uniport Id BXGT Id Protein Name Status Protein Class Gene Ki nM ic50 nM Kd nM Ka M-1
Binding DB 50350760
Uniport Id BXGT Id Protein Name Status Protein Class Gene Ki nM ic50 nM Kd nM EC50 nM
Uniport Id BXGT Id Protein Name Status Protein Class Gene Ki nM ic50 nM Kd nM EC50 nM
reviewed BXGT012651 Lactase-phlorizin hydrolase reviewed Lct - 122000 - -
reviewed BXGT008901 Sucrase-isomaltase, intestinal reviewed Si - 225000 - -
reviewed BXGT015223 Beta-galactosidase reviewed GLB1 - 960000 - -
reviewed BXGT014117 Tissue alpha-L-fucosidase reviewed FUCA1 - 260000 - -
reviewed BXGT005280 Ceramide glucosyltransferase reviewed Ugcg - >10000 - -
reviewed BXGT020533 Non-lysosomal glucosylceramidase reviewed GBA2 - 30000 - -
CHEMBL CHEMBL1818436
Uniport Id BXGT Id Protein Name Status Protein Class Gene width="10%">Type Relation value Units
Uniport Id BXGT Id Protein Name Status Protein Class Gene Type Relation value Units
Q2KIM0 BXGT014117 Tissue alpha-L-fucosidase reviewed - FUCA1 IC50 '=' 260000 nM
P23739 BXGT008901 Sucrase-isomaltase, intestinal reviewed - Si Inhibition '<' 50 %
P04062 BXGT006140 Lysosomal acid glucosylceramidase reviewed - GBA Inhibition '<' 50 %
Q2KHZ8 BXGT014115 Lysosomal acid glucosylceramidase reviewed - GBA Inhibition '<' 50 %
O88693 BXGT005280 Ceramide glucosyltransferase reviewed - Ugcg IC50 '>' 10000 nM
O88693 BXGT005280 Ceramide glucosyltransferase reviewed - Ugcg Inhibition - - -
P23739 BXGT008901 Sucrase-isomaltase, intestinal reviewed - Si IC50 '=' 225000 nM
Q58D55 BXGT015223 Beta-galactosidase reviewed - GLB1 IC50 '=' 960000 nM
Q02401 BXGT012651 Lactase-phlorizin hydrolase reviewed - Lct IC50 '=' 122000 nM
Q9HCG7 BXGT020533 Non-lysosomal glucosylceramidase reviewed - GBA2 IC50 '=' 30000 nM
Foods  containing  the  compound
Foods
BXGF Id Food Name Scientific Name Food Group
BXGF Id Food Name Scientific Name Food Group
BXGF04607 Morus alba Morus alba Medicinal Plant
BXGF06217 Morus mongolica Morus mongolica Medicinal Plant
The  compound-realted  diseases
Diseases
BXGD Id Disease Name CUI Disease Id Disease Class Name Number of targets?Number of targets related to compound connecting disease, higher numbers indicate the compound is more associated with the disease