acompound

Showing entry for Leucovorin

　　　　　　　　　　　　　　　

General Compound Information
BXGC Id	BXGC0018829
Compound Name	Leucovorin
Structure
Formula	C20H23N7O7
InchiKey	VVIAGPKUTFNRDU-OLZOCXBDSA-N
SMILES	O=CN1[C@H](CNc2ccc(cc2)C(=O)N[C@H](C(=O)O)CCC(=O)O)CNc2c1c(O)nc(=N)[nH]2
Inchi	InChI=1S/C20H23N7O7/c21-20-25-16-15(18(32)26-20)27(9-28)12(8-23-16)7-22-11-3-1-10(2-4-11)17(31)24-13(19(33)34)5-6-14(29)30/h1-4,9,12-13,22H,5-8H2,(H,24,31)(H,29,30)(H,33,34)(H4,21,23,25,26,32)/t12-,13+/m1/s1
IUPAC	(2S)-2-[[4-[[(6R)-2-amino-5-formyl-4-oxo-1,6,7,8-tetrahydropteridin-6-yl]methylamino]benzoyl]amino]pentanedioic acid
Molecular Weight	473.17
Pubchem Id	135484651
Chembl Id	CHEMBL1232801

Targets of Information Source

DrugBank

Uniport Id	BXGT Id	Protein Name	Status	Protein Class	Gene	Groups	Target Type
Uniport Id	BXGT Id	Protein Name	Status	Protein Class	Gene	Groups	Target Type
Q9AGP8	BXGT020063	Dimethylglycine oxidase	reviewed	-	dmg	experimental	-
Q5KUI2	BXGT015464	Serine hydroxymethyltransferase	reviewed	-	glyA	experimental	-
Q9WY54	BXGT021973	Aminomethyltransferase	reviewed	-	gcvT	experimental	-
P77398	BXGT011806	Bifunctional polymyxin resistance protein ArnA	reviewed	-	arnA	experimental	-
O95954	BXGT005408	Formimidoyltransferase-cyclodeaminase	reviewed	Enzyme	FTCD	experimental	-

PDB

Uniport Id	BXGT Id	Protein Name	Status	Protein Class	Gene	Ki nM	ic50 nM	Kd nM	Ka M-1
Uniport Id	BXGT Id	Protein Name	Status	Protein Class	Gene	Ki nM	ic50 nM	Kd nM	Ka M-1
Q7SIB6	BXGT017110	Serine hydroxymethyltransferase	unreviewed	glyA	-	-	-	-	-
P53603	BXGT010999	Formimidoyltransferase-cyclodeaminase	reviewed	FTCD	-	-	-	-	-
Q50LF0	BXGT014944	Sarcosine oxidase subunit alpha	unreviewed	soxA	-	-	-	-	-
Q9WYA4	BXGT021983	tRNA modification GTPase MnmE	reviewed	mnmE	-	-	-	-	-
P77398	BXGT011806	Bifunctional polymyxin resistance protein ArnA	reviewed	arnA	-	-	-	-	-
Q8KAS1	BXGT018407	tRNA modification GTPase MnmE	reviewed	mnmE	-	-	-	-	-
Q8YN91	BXGT019135	tRNA modification GTPase MnmE	reviewed	mnmE	-	-	-	-	-
A5K8L9	BXGT001342	Serine hydroxymethyltransferase, putative	unreviewed	PVX_100730	-	-	-	-	-
F8RC03	BXGT003322	Qdtf	unreviewed	qdtf	-	-	-	-	-
Q70LM7	BXGT016682	Linear gramicidin synthase subunit A	reviewed	lgrA	-	-	-	-	-
U3GK13	BXGT022561	Formyltransferase	unreviewed	fdtF	-	-	-	-	-
R4MIX2	BXGT022499	Uncharacterized protein	unreviewed	J113_23825	-	-	-	-	-
F8WJP6	BXGT003332	Gdp-mannose 4,6-dehydratase / gdp-4-amino-4,6-dideoxy-d-mannose formyltransferase	unreviewed	BMEI1418	-	-	-	-	-
A0A4P1LYI6	BXGT024932	N-formyltransferase	unreviewed	SAMN03097714_1080	-	-	-	-	-

Binding DB

n.a

Uniport Id	BXGT Id	Protein Name	Status	Protein Class	Gene	Ki nM	ic50 nM	Kd nM	EC50 nM
Uniport Id	BXGT Id	Protein Name	Status	Protein Class	Gene	Ki nM	ic50 nM	Kd nM	EC50 nM

CHEMBL

Uniport Id	BXGT Id	Protein Name	Status	Protein Class	Gene	width="10%">Type	Relation	value	Units
Uniport Id	BXGT Id	Protein Name	Status	Protein Class	Gene	Type	Relation	value	Units

Foods containing the compound

Foods

BXGF Id	Food Name	Scientific Name	Food Group
BXGF Id	Food Name	Scientific Name	Food Group
BXGF01140	Angelica gigas	Angelica gigas	Medicinal Plant
BXGF02049	Angelica sinensis	Angelica sinensis	Medicinal Plant
BXGF04842	Angelica acutiloba	Angelica acutiloba	Medicinal Plant

The compound-realted diseases

Diseases

BXGD Id	Disease Name	CUI Disease Id	Disease Class Name	Number of targets^{?Number of targets related to compound connecting disease, higher numbers indicate the compound is more associated with the disease}