acompound

Showing entry for Hippuristanol

　　　　　　　　　　　　　　　

General Compound Information
BXGC Id	BXGC0020869
Compound Name	Hippuristanol
Structure
Formula	C28H46O5
InchiKey	HPHXKNOXVBFETI-SHCCRYCOSA-N
SMILES	O[C@@H]1CC[C@]2([C@H](C1)CC[C@@H]1[C@@H]2[C@@H](O)C[C@]2([C@H]1C[C@H]1[C@@H]2[C@@](C)(O)[C@@]2(O1)C[C@@H](C(O2)(C)C)C)C)C
Inchi	InChI=1S/C28H46O5/c1-15-13-28(33-24(15,2)3)27(6,31)23-21(32-28)12-19-18-8-7-16-11-17(29)9-10-25(16,4)22(18)20(30)14-26(19,23)5/h15-23,29-31H,7-14H2,1-6H3/t15-,16-,17+,18-,19-,20-,21-,22+,23-,25-,26-,27+,28+/m0/s1
IUPAC
Molecular Weight	462.33
Pubchem Id	9981822
Chembl Id	CHEMBL1098427

Targets of Information Source

DrugBank

n.a

Uniport Id	BXGT Id	Protein Name	Status	Protein Class	Gene	Groups	Target Type
Uniport Id	BXGT Id	Protein Name	Status	Protein Class	Gene	Groups	Target Type

PDB

n.a

Uniport Id	BXGT Id	Protein Name	Status	Protein Class	Gene	Ki nM	ic50 nM	Kd nM	Ka M-1
Uniport Id	BXGT Id	Protein Name	Status	Protein Class	Gene	Ki nM	ic50 nM	Kd nM	Ka M-1

Binding DB

n.a

Uniport Id	BXGT Id	Protein Name	Status	Protein Class	Gene	Ki nM	ic50 nM	Kd nM	EC50 nM
Uniport Id	BXGT Id	Protein Name	Status	Protein Class	Gene	Ki nM	ic50 nM	Kd nM	EC50 nM

CHEMBL

Uniport Id	BXGT Id	Protein Name	Status	Protein Class	Gene	width="10%">Type	Relation	value	Units
Uniport Id	BXGT Id	Protein Name	Status	Protein Class	Gene	Type	Relation	value	Units
P29562	BXGT009364	Eukaryotic initiation factor 4A-I	reviewed	-	EIF4A1	Inhibition	-	-	-
P60843	BXGT011331	Eukaryotic initiation factor 4A-I	reviewed	-	Eif4a1	Inhibition	-	-	-
P60843	BXGT011331	Eukaryotic initiation factor 4A-I	reviewed	-	Eif4a1	IC50	'='	400	nM
P60842	BXGT011330	Eukaryotic initiation factor 4A-I	reviewed	-	EIF4A1	Inhibition	-	-	-
P23588	BXGT008887	Eukaryotic translation initiation factor 4B	reviewed	Nucleic acid binding	EIF4B	Inhibition	-	-	-
P06730	BXGT006487	Eukaryotic translation initiation factor 4E	reviewed	Nucleic acid binding	EIF4E	Inhibition	-	-	-
P60842	BXGT011330	Eukaryotic initiation factor 4A-I	reviewed	-	EIF4A1	IC50	'='	3100	nM
P38919	BXGT010072	Eukaryotic initiation factor 4A-III	reviewed	-	EIF4A3	Activity	-	-	-
P41378	BXGT010257	Eukaryotic initiation factor 4A	reviewed	-		Inhibition	-	-	-
P60842	BXGT011330	Eukaryotic initiation factor 4A-I	reviewed	-	EIF4A1	FC	'='	2	-
O75643	BXGT005142	U5 small nuclear ribonucleoprotein 200 kDa helicase	reviewed	-	SNRNP200	IC50	'>'	30000	nM
P38919	BXGT010072	Eukaryotic initiation factor 4A-III	reviewed	-	EIF4A3	K	'='	1	10'3/M/s
P38919	BXGT010072	Eukaryotic initiation factor 4A-III	reviewed	-	EIF4A3	Kd	'='	50000	nM
P38919	BXGT010072	Eukaryotic initiation factor 4A-III	reviewed	-	EIF4A3	K	'='	5	10'-2/s
Q7Z478	BXGT017253	ATP-dependent RNA helicase DHX29	reviewed	Enzyme	DHX29	IC50	'>'	30000	nM
P38919	BXGT010072	Eukaryotic initiation factor 4A-III	reviewed	-	EIF4A3	IC50	'='	40000	nM
P38919	BXGT010072	Eukaryotic initiation factor 4A-III	reviewed	-	EIF4A3	T1/2	'='	0	hr
Q14240	BXGT013458	Eukaryotic initiation factor 4A-II	reviewed	-	EIF4A2	IC50	'='	18000	nM

Foods containing the compound

Foods

BXGF Id	Food Name	Scientific Name	Food Group
BXGF Id	Food Name	Scientific Name	Food Group
BXGF04787	Valeriana jatamansi	Valeriana jatamansi	Medicinal Plant

The compound-realted diseases

Diseases

BXGD Id	Disease Name	CUI Disease Id	Disease Class Name	Number of targets^{?Number of targets related to compound connecting disease, higher numbers indicate the compound is more associated with the disease}