acompound

Showing entry for D-Leucine

　　　　　　　　　　　　　　　

General Compound Information
BXGC Id	BXGC0020943
Compound Name	D-Leucine
Structure
Formula	C6H13NO2
InchiKey	ROHFNLRQFUQHCH-RXMQYKEDSA-N
SMILES	N[C@@H](C(=O)O)CC(C)C
Inchi	InChI=1S/C6H13NO2/c1-4(2)3-5(7)6(8)9/h4-5H,3,7H2,1-2H3,(H,8,9)/t5-/m1/s1
IUPAC	(2R)-2-amino-4-methylpentanoic acid
Molecular Weight	131.09
Pubchem Id	439524
Chembl Id	CHEMBL1232258

Targets of Information Source

DrugBank

n.a

Uniport Id	BXGT Id	Protein Name	Status	Protein Class	Gene	Groups	Target Type
Uniport Id	BXGT Id	Protein Name	Status	Protein Class	Gene	Groups	Target Type

PDB

Uniport Id	BXGT Id	Protein Name	Status	Protein Class	Gene	Ki nM	ic50 nM	Kd nM	Ka M-1
Uniport Id	BXGT Id	Protein Name	Status	Protein Class	Gene	Ki nM	ic50 nM	Kd nM	Ka M-1
P56254	BXGT011160	Kalata-B1	reviewed	OAK1	-	-	-	-	-
P02640	BXGT005907	Villin-1	reviewed	VIL1	-	-	-	-	-
Q890V3	BXGT017734	Meso-diaminopimelate D-dehydrogenase	unreviewed	CTC_02532	-	-	-	-	-
Q948Z4	BXGT019557	Snakin-1	reviewed	SN1	-	-	-	-	-
P62987	BXGT011478	Ubiquitin-60S ribosomal protein L40	reviewed	UBA52	Nucleic acid binding	-	-	-	-
P22629	BXGT008788	Streptavidin	reviewed		-	-	-	-	-
P0CG47	BXGT007467	Polyubiquitin-B	reviewed	UBB	Nucleic acid binding	-	-	-	-
A0A679G4U8	BXGT024695	Thioesterase	unreviewed	surE	-	-	-	-	-
P01501	BXGT025041	Melittin	reviewed	MELT	-	-	-	-	-

Binding DB

n.a

Uniport Id	BXGT Id	Protein Name	Status	Protein Class	Gene	Ki nM	ic50 nM	Kd nM	EC50 nM
Uniport Id	BXGT Id	Protein Name	Status	Protein Class	Gene	Ki nM	ic50 nM	Kd nM	EC50 nM

CHEMBL

Uniport Id	BXGT Id	Protein Name	Status	Protein Class	Gene	width="10%">Type	Relation	value	Units
Uniport Id	BXGT Id	Protein Name	Status	Protein Class	Gene	Type	Relation	value	Units
P02545	BXGT005889	Prelamin-A/C	reviewed	-	LMNA	Potency	'='	501	nM
P49798	BXGT010745	Regulator of G-protein signaling 4	reviewed	Enzyme modulator	RGS4	Potency	-	37685	nM
Q91Y77	BXGT019323	Monocarboxylate transporter 10	reviewed	-	Slc16a10	Activity	-	-	-
P97697	BXGT012214	Inositol monophosphatase 1	reviewed	-	Impa1	Potency	'='	5011	nM
Q01650	BXGT012603	Large neutral amino acids transporter small subunit 1	reviewed	Transporter	SLC7A5	IC50	'='	220000	nM
Q01650	BXGT012603	Large neutral amino acids transporter small subunit 1	reviewed	Transporter	SLC7A5	Activity	'='	100	%
Q01650	BXGT012603	Large neutral amino acids transporter small subunit 1	reviewed	Transporter	SLC7A5	Inhibition	'='	56	%

Foods containing the compound

Foods

BXGF Id	Food Name	Scientific Name	Food Group
BXGF Id	Food Name	Scientific Name	Food Group
BXGF00008	Garlic	Allium sativum	Herbs and Spices
BXGF00027	Chinese mustard	Brassica juncea	Vegetables
BXGF00337	Ginkgo nuts	Ginkgo biloba	Herbs and Spices
BXGF00380	White mustard	Sinapis alba	Herbs and Spices
BXGF01426	Cornus officinalis	Cornus officinalis	Medicinal Plant
BXGF05421	Tussilago farfara	Tussilago farfara	Medicinal Plant
BXGF06108	Centipeda minima	Centipeda minima	Medicinal Plant

The compound-realted diseases

Diseases

BXGD Id	Disease Name	CUI Disease Id	Disease Class Name	Number of targets^{?Number of targets related to compound connecting disease, higher numbers indicate the compound is more associated with the disease}