Showing entry for Fagomine


　 　 　 　 　 　 　 　 　 　 　 　 　 　 　
General Compound Information
BXGC IdBXGC0025338
Compound NameFagomine
Structure
FormulaC6H13NO3
InchiKeyYZNNBIPIQWYLDM-SRQIZXRXSA-N
SMILESOC[C@H]1NCC[C@@H]([C@H]1O)O
InchiInChI=1S/C6H13NO3/c8-3-4-6(10)5(9)1-2-7-4/h4-10H,1-3H2/t4-,5+,6+/m1/s1
IUPAC(2R,3S,4S)-2-(hydroxymethyl)piperidine-3,4-diol
Molecular Weight147.09
Pubchem Id10678391
Chembl IdCHEMBL505237
Targets of Information Source
DrugBank n.a
Uniport Id BXGT Id Protein Name Status Protein Class Gene Groups Target Type
Uniport Id BXGT Id Protein Name Status Protein Class Gene Groups Target Type
PDB n.a
Uniport Id BXGT Id Protein Name Status Protein Class Gene Ki nM ic50 nM Kd nM Ka M-1
Uniport Id BXGT Id Protein Name Status Protein Class Gene Ki nM ic50 nM Kd nM Ka M-1
Binding DB 50379060
Uniport Id BXGT Id Protein Name Status Protein Class Gene Ki nM ic50 nM Kd nM EC50 nM
Uniport Id BXGT Id Protein Name Status Protein Class Gene Ki nM ic50 nM Kd nM EC50 nM
reviewed BXGT005280 Ceramide glucosyltransferase reviewed Ugcg - >10000 - -
reviewed BXGT020533 Non-lysosomal glucosylceramidase reviewed GBA2 - >1000000 - -
CHEMBL CHEMBL505237
Uniport Id BXGT Id Protein Name Status Protein Class Gene width="10%">Type Relation value Units
Uniport Id BXGT Id Protein Name Status Protein Class Gene Type Relation value Units
P23739 BXGT008901 Sucrase-isomaltase, intestinal reviewed - Si Inhibition '<' 50 %
O88693 BXGT005280 Ceramide glucosyltransferase reviewed - Ugcg IC50 '>' 10000 nM
Q2KHZ8 BXGT014115 Lysosomal acid glucosylceramidase reviewed - GBA Inhibition '<' 50 %
Q02401 BXGT012651 Lactase-phlorizin hydrolase reviewed - Lct Inhibition '<' 50 %
Q58D55 BXGT015223 Beta-galactosidase reviewed - GLB1 Inhibition '<' 50 %
Q9HCG7 BXGT020533 Non-lysosomal glucosylceramidase reviewed - GBA2 IC50 '>' 1000000 nM
Q2KIM0 BXGT014117 Tissue alpha-L-fucosidase reviewed - FUCA1 Inhibition '<' 50 %
O88693 BXGT005280 Ceramide glucosyltransferase reviewed - Ugcg Inhibition - - -
P04062 BXGT006140 Lysosomal acid glucosylceramidase reviewed - GBA Inhibition '<' 50 %
Foods  containing  the  compound
Foods
BXGF Id Food Name Scientific Name Food Group
BXGF Id Food Name Scientific Name Food Group
BXGF03204 Xanthocercis zambesiaca Xanthocercis zambesiaca Others
The  compound-realted  diseases
Diseases
BXGD Id Disease Name CUI Disease Id Disease Class Name Number of targets?Number of targets related to compound connecting disease, higher numbers indicate the compound is more associated with the disease