Showing entry for Koparin


　 　 　 　 　 　 　 　 　 　 　 　 　 　 　
General Compound Information
BXGC IdBXGC0025653
Compound NameKoparin
Structure
FormulaC16H12O6
InchiKeySMOFGXHPWCTYQD-UHFFFAOYSA-N
SMILESCOc1ccc(c(c1O)O)c1coc2c(c1=O)ccc(c2)O
InchiInChI=1S/C16H12O6/c1-21-12-5-4-9(15(19)16(12)20)11-7-22-13-6-8(17)2-3-10(13)14(11)18/h2-7,17,19-20H,1H3
IUPAC3-(2,3-dihydroxy-4-methoxyphenyl)-7-hydroxychromen-4-one
Molecular Weight300.06
Pubchem Id5318834
Chembl IdCHEMBL1354502
Targets of Information Source
DrugBank n.a
Uniport Id BXGT Id Protein Name Status Protein Class Gene Groups Target Type
Uniport Id BXGT Id Protein Name Status Protein Class Gene Groups Target Type
PDB n.a
Uniport Id BXGT Id Protein Name Status Protein Class Gene Ki nM ic50 nM Kd nM Ka M-1
Uniport Id BXGT Id Protein Name Status Protein Class Gene Ki nM ic50 nM Kd nM Ka M-1
Binding DB n.a
Uniport Id BXGT Id Protein Name Status Protein Class Gene Ki nM ic50 nM Kd nM EC50 nM
Uniport Id BXGT Id Protein Name Status Protein Class Gene Ki nM ic50 nM Kd nM EC50 nM
CHEMBL CHEMBL1354502
Uniport Id BXGT Id Protein Name Status Protein Class Gene width="10%">Type Relation value Units
Uniport Id BXGT Id Protein Name Status Protein Class Gene Type Relation value Units
Q92830 BXGT019379 Histone acetyltransferase KAT2A reviewed - KAT2A Potency - 39810 nM
Q9NUW8 BXGT021219 Tyrosyl-DNA phosphodiesterase 1 reviewed Enzyme TDP1 Potency - 25929 nM
P11473 BXGT007709 Vitamin D3 receptor reviewed Nuclear receptor VDR Potency - 50118 nM
Q9NUW8 BXGT021219 Tyrosyl-DNA phosphodiesterase 1 reviewed Enzyme TDP1 Potency '=' 1000 nM
P10636 BXGT007596 Microtubule-associated protein tau reviewed - MAPT Potency '=' 10000 nM
O94782 BXGT005332 Ubiquitin carboxyl-terminal hydrolase 1 reviewed Enzyme USP1 Potency - 56234 nM
Q9NUW8 BXGT021219 Tyrosyl-DNA phosphodiesterase 1 reviewed Enzyme TDP1 Potency - 29092 nM
P15428 BXGT008121 15-hydroxyprostaglandin dehydrogenase [NAD(+)] reviewed - HPGD Potency '=' 7079 nM
Q9UBT6 BXGT021664 DNA polymerase kappa reviewed - POLK Potency - 1778 nM
P46063 BXGT010501 ATP-dependent DNA helicase Q1 reviewed Enzyme RECQL Potency '=' 3981 nM
Q9NPD5 BXGT021151 Solute carrier organic anion transporter family member 1B3 reviewed Transporter SLCO1B3 Inhibition '=' 86 %
P10636 BXGT007596 Microtubule-associated protein tau reviewed - MAPT Potency '=' 15848 nM
O97447 BXGT005436 Putative fructose-1,6-bisphosphate aldolase unreviewed - ald Potency '=' 17740 nM
P10636 BXGT007596 Microtubule-associated protein tau reviewed - MAPT Potency '=' 12589 nM
P16050 BXGT008184 Arachidonate 15-lipoxygenase reviewed Enzyme ALOX15 Potency '=' 12589 nM
P00352 BXGT005510 Retinal dehydrogenase 1 reviewed Enzyme ALDH1A1 Potency '=' 8912 nM
P27695 BXGT009199 DNA-(apurinic or apyrimidinic site) lyase reviewed - APEX1 Potency - 3162 nM
Q99714 BXGT019954 3-hydroxyacyl-CoA dehydrogenase type-2 reviewed Enzyme HSD17B10 Potency '=' 15848 nM
B2RXH2 BXGT002006 Lysine-specific demethylase 4E reviewed - KDM4E Potency '=' 11220 nM
Q9Y6L6 BXGT022334 Solute carrier organic anion transporter family member 1B1 reviewed Transporter SLCO1B1 Inhibition '=' 88 %
Foods  containing  the  compound
Foods
BXGF Id Food Name Scientific Name Food Group
BXGF Id Food Name Scientific Name Food Group
BXGF00916 Erythrina speciosa Erythrina speciosa Others
BXGF00978 Prunus prostrata Prunus prostrata Medicinal Plant
BXGF01168 Erysimum leptophyllum Erysimum leptophyllum Others
BXGF01295 Chondrodendron tomentosum Chondrodendron tomentosum Medicinal Plant
BXGF01354 Haplophyllum obtusifolium Haplophyllum obtusifolium Others
BXGF01621 Syzygium polycephaloides Syzygium polycephaloides Human Edible Plant
BXGF02202 Piper regnellii Piper regnellii Medicinal Plant
BXGF02287 Gymnocalycium schickendantzii Gymnocalycium schickendantzii Others
BXGF02445 Onopordum acanthium Onopordum acanthium Medicinal Plant
BXGF02500 Pancratium sickenbergeri Pancratium sickenbergeri Others
BXGF02560 Richteria pyrethroides Richteria pyrethroides Others
BXGF02573 Centaurea maculosa Centaurea maculosa Others
BXGF02626 Dalbergia odorifera Dalbergia odorifera Medicinal Plant
BXGF02635 Ephedra sinica Ephedra sinica Medicinal Plant
BXGF02695 Plathymenia reticulata Plathymenia reticulata Others
BXGF02729 Asimina parviflora Asimina parviflora Medicinal Plant
BXGF02774 Pteridium esculentum Pteridium esculentum Medicinal Plant
BXGF02813 Esenbeckia leiocarpa Esenbeckia leiocarpa Others
BXGF02852 Sophora flavescens Sophora flavescens Medicinal Plant
BXGF02929 Hypericum styphelioides Hypericum styphelioides Others
BXGF02973 Vellozia nanuzae Vellozia nanuzae Others
BXGF02992 Baccharis neglecta Baccharis neglecta Others
BXGF03012 Atraphaxis spinosa Atraphaxis spinosa Medicinal Plant
BXGF03027 Embelia schimperi Embelia schimperi Medicinal Plant
BXGF03087 Epilobium hirsutum Epilobium hirsutum Medicinal Plant
BXGF03106 Lythrum salicaria Lythrum salicaria Medicinal Plant
BXGF03113 Simarouba glauca Simarouba glauca Medicinal Plant
BXGF03126 Erythrina melanacantha Erythrina melanacantha Medicinal Plant
BXGF03151 Monsonia senegalensis Monsonia senegalensis Human Edible Plant
BXGF03157 Clerodendrum bungei Clerodendrum bungei Medicinal Plant
BXGF03186 Lemaireocereus longispinus Lemaireocereus longispinus Others
BXGF03197 Eria anomala Eria anomala Others
BXGF03208 Embelia parviflora Embelia parviflora Medicinal Plant
BXGF03250 Euphorbia nematocypha Euphorbia nematocypha Medicinal Plant
BXGF03279 Abelia chinensis Abelia chinensis Unclassified
BXGF03297 Diospyros assimilis Diospyros assimilis Medicinal Plant
BXGF03310 Faramea salicifolia Faramea salicifolia Others
BXGF03564 Vernonia fagifolia Vernonia fagifolia Others
BXGF03570 Cordia leucocephala Cordia leucocephala Others
BXGF04099 Piper divaricatum Piper divaricatum Others
BXGF04110 Helichrysum drakensbergense Helichrysum drakensbergense Others
BXGF04167 Santolina pectinata Santolina pectinata Others
BXGF04185 Prosopis africana Prosopis africana Medicinal Plant
BXGF04364 Commiphora sphaerocarpa Commiphora sphaerocarpa Others
BXGF04374 Satureja vulgaris Satureja vulgaris Others
BXGF04584 Helichrysum tenuifolium Helichrysum tenuifolium Others
BXGF05010 Morella rubra Morella rubra 0
The  compound-realted  diseases
Diseases
BXGD Id Disease Name CUI Disease Id Disease Class Name Number of targets?Number of targets related to compound connecting disease, higher numbers indicate the compound is more associated with the disease