Showing entry for ATP-dependent DNA helicase Q1


　 　 　 　 　 　 　 　 　 　 　 　
General Target Information
BXGT IdBXGT010501
Protein NameATP-dependent DNA helicase Q1
Uniport IdP46063
GeneRECQL
Gene Id5965
DomainDEAD; Helicase_C; RecQ_Zn_bind
Pfam PF00270   PF00271   PF16124  
OrganismHomo sapiens (Human)
Target protein  affiliated  biological  pathways
KEGG
Class Subclass KEGG Id Pathway Name
Gene Ontology
GO Type GO Id Gene Ontology
Biological Process GO:0032508 DNA duplex unwinding
Biological Process GO:0006310 DNA recombination
Biological Process GO:0006281 DNA repair
Biological Process GO:0000733 DNA strand renaturation
Biological Process GO:0006268 DNA unwinding involved in DNA replication
Biological Process GO:0000724 double-strand break repair via homologous recombination
molecular function GO:0043138 3'-5' DNA helicase activity
molecular function GO:0036310 annealing helicase activity
molecular function GO:0005524 ATP binding
molecular function GO:0003677 DNA binding
molecular function GO:0003678 DNA helicase activity
molecular function GO:0009378 four-way junction helicase activity
cellular component GO:0005694 chromosome
cellular component GO:0005737 cytoplasm
cellular component GO:0016020 membrane
cellular component GO:0005654 nucleoplasm
cellular component GO:0005634 nucleus
Reactome
Pathway Id Pathway Name
Target protein-related  diseases
Disease
CUI Id BXGD Id Disease Name Disease Class
C0001418 BXGD000050 Adenocarcinoma Neoplasms
C0006142 BXGD000374 Malignant neoplasm of breast Neoplasms; Skin and Connective Tissue Diseases
C0006826 BXGD000408 Malignant Neoplasms Neoplasms
C0007107 BXGD000428 Malignant neoplasm of larynx Neoplasms; Respiratory Tract Diseases; Otorhinolaryngologic Diseases
C0007131 BXGD000441 Non-Small Cell Lung Carcinoma Neoplasms; Respiratory Tract Diseases
C0017636 BXGD001131 Glioblastoma Neoplasms
C0023530 BXGD001683 Leukopenia Hemic and Lymphatic Diseases
C0026764 BXGD001928 Multiple Myeloma Neoplasms; Immune System Diseases; Hemic and Lymphatic Diseases; Cardiovascular Diseases
C0027627 BXGD002006 Neoplasm Metastasis Pathological Conditions, Signs and Symptoms; Neoplasms
C0027651 BXGD002009 Neoplasms Neoplasms
C0027672 BXGD002020 Neoplastic Syndromes, Hereditary Congenital, Hereditary, and Neonatal Diseases and Abnormalities; Neoplasms
C0029463 BXGD002160 Osteosarcoma Neoplasms
C0032339 BXGD002352 Rothmund-Thomson syndrome Congenital, Hereditary, and Neonatal Diseases and Abnormalities; Nutritional and Metabolic Diseases; Skin and Connective Tissue Diseases
C0036220 BXGD002587 Kaposi Sarcoma Neoplasms; Infections
C0043119 BXGD003029 Werner Syndrome Congenital, Hereditary, and Neonatal Diseases and Abnormalities; Nutritional and Metabolic Diseases
C0043346 BXGD003043 Xeroderma Pigmentosum Congenital, Hereditary, and Neonatal Diseases and Abnormalities; Neoplasms; Nutritional and Metabolic Diseases; Skin and Connective Tissue Diseases
C0162429 BXGD003942 Malnutrition Nutritional and Metabolic Diseases
C0178874 BXGD004037 Tumor Progression Pathological Conditions, Signs and Symptoms
C0220630 BXGD004302 Adult Liver Carcinoma Digestive System Diseases; Neoplasms
C0235974 BXGD004796 Pancreatic carcinoma Digestive System Diseases; Neoplasms; Endocrine System Diseases
C0242379 BXGD005157 Malignant neoplasm of lung Neoplasms; Respiratory Tract Diseases
C0278878 BXGD006609 Adult Glioblastoma Neoplasms
C0279000 BXGD006622 Liver and Intrahepatic Biliary Tract Carcinoma Digestive System Diseases; Neoplasms
C0280100 BXGD006713 Solid Neoplasm Neoplasms
C0280474 BXGD006748 Childhood Glioblastoma Neoplasms
C0281361 BXGD006774 Adenocarcinoma of pancreas Digestive System Diseases; Neoplasms; Endocrine System Diseases
C0345904 BXGD007745 Malignant neoplasm of liver Digestive System Diseases; Neoplasms
C0346153 BXGD007781 Breast Cancer, Familial Neoplasms; Skin and Connective Tissue Diseases
C0346647 BXGD007832 Malignant neoplasm of pancreas Digestive System Diseases; Neoplasms; Endocrine System Diseases
C0349566 BXGD007928 Squamous cell carcinoma of tongue Neoplasms; Stomatognathic Diseases
C0585442 BXGD009593 Osteosarcoma of bone Neoplasms
C0595989 BXGD009632 Carcinoma of larynx Neoplasms; Respiratory Tract Diseases; Otorhinolaryngologic Diseases
C0596263 BXGD009639 Carcinogenesis Pathological Conditions, Signs and Symptoms; Neoplasms
C0677886 BXGD009734 Epithelial ovarian cancer Neoplasms; Female Urogenital Diseases and Pregnancy Complications; Endocrine System Diseases
C0678222 BXGD009749 Breast Carcinoma Neoplasms; Skin and Connective Tissue Diseases
C0684249 BXGD009790 Carcinoma of lung Neoplasms; Respiratory Tract Diseases
C0686619 BXGD009835 Secondary malignant neoplasm of lymph node Pathological Conditions, Signs and Symptoms; Neoplasms
C0854778 BXGD011033 Pancreatic carcinoma resectable Digestive System Diseases; Neoplasms; Endocrine System Diseases
C0919267 BXGD011426 ovarian neoplasm Neoplasms; Female Urogenital Diseases and Pregnancy Complications; Endocrine System Diseases
C1140680 BXGD011718 Malignant neoplasm of ovary Neoplasms; Female Urogenital Diseases and Pregnancy Complications; Endocrine System Diseases
C1168401 BXGD011792 Squamous cell carcinoma of the head and neck Neoplasms
C1257931 BXGD011815 Mammary Neoplasms, Human Neoplasms; Skin and Connective Tissue Diseases
C1269955 BXGD012005 Tumor Cell Invasion
C1306459 BXGD012361 Primary malignant neoplasm Neoplasms
C1306460 BXGD012362 Primary malignant neoplasm of lung Neoplasms; Respiratory Tract Diseases
C1332986 BXGD012574 Childhood Osteosarcoma Neoplasms
C1458155 BXGD013136 Mammary Neoplasms Neoplasms; Skin and Connective Tissue Diseases
C1621958 BXGD013468 Glioblastoma Multiforme Neoplasms
C2239176 BXGD016965 Liver carcinoma Digestive System Diseases; Neoplasms
C2752147 BXGD017769 XERODERMA PIGMENTOSUM, COMPLEMENTATION GROUP C Congenital, Hereditary, and Neonatal Diseases and Abnormalities; Neoplasms; Nutritional and Metabolic Diseases; Skin and Connective Tissue Diseases
C3539878 BXGD019087 Triple Negative Breast Neoplasms Neoplasms; Skin and Connective Tissue Diseases
C3642345 BXGD019244 Luminal A Breast Carcinoma
C3642346 BXGD019245 Luminal B Breast Carcinoma
C3665419 BXGD019285 intracranial glioma Neoplasms; Nervous System Diseases
C4048328 BXGD021903 cervical cancer Neoplasms; Female Urogenital Diseases and Pregnancy Complications
C4704874 BXGD023682 Mammary Carcinoma, Human Neoplasms; Skin and Connective Tissue Diseases
C4721610 BXGD023760 Carcinoma, Ovarian Epithelial Neoplasms; Female Urogenital Diseases and Pregnancy Complications; Endocrine System Diseases
C4722518 BXGD023806 Triple-Negative Breast Carcinoma Neoplasms; Skin and Connective Tissue Diseases
Target protein-related  compounds
Compounds
BXGC Id Compound Name Strcuture Molecular Weight
BXGC0000130 Estradiol 272.38
BXGC0000242 L-Canavanine 176.17
BXGC0000286 L-DOPA 197.19
BXGC0000323 Isotheaflavin 564.49
BXGC0000324 Isovitexin 432.38
BXGC0000332 Fisetin 286.24
BXGC0000392 Eriodictyol 288.26
BXGC0000430 Gossypol 518.55
BXGC0000461 Tricetin 302.24
BXGC0000530 Hydroquinone 110.11
BXGC0000655 Harmalol 200.24
BXGC0001002 1,2-Benzenediol 110.11
BXGC0001544 Harmaline 214.26
BXGC0001615 (E)-Zeatin 219.24
BXGC0001691 Questiomycin A 212.2
BXGC0001742 Eupafolin 316.26
BXGC0001746 Theaflavin 3,3'-digallate 868.7
BXGC0001747 Rosmarinic acid 360.31
BXGC0001868 Catechin 290.27
BXGC0001881 Chrysophanol 254.24
BXGC0001991 Juglone 174.15
BXGC0002018 Morin 302.24
BXGC0002029 Taxifolin 304.25
BXGC0002094 Rhamnetin 316.26
BXGC0002390 Spermine 202.34
BXGC0002588 Magnesium 24.31
BXGC0002971 alpha-Lipoic acid 206.33
BXGC0003273 3-O-Methylkaempferol 300.26
BXGC0003456 1,4-Benzoquinone 108.09
BXGC0003487 Plumbagin 188.18
BXGC0003696 Quercetin 3-O-methyl-ether 316.26
BXGC0003705 Chloride 35.45
BXGC0004322 xi-3-Hydroxy-5-phenylpentanoic acid O-beta-D-Glucopyranoside 356.37
BXGC0004497 3-O-Acetylepisamarcandin 442.54
BXGC0004556 1,2,3-Benzenetriol 126.11
BXGC0004965 Rhein 284.22
BXGC0004969 1,4,5-Naphthalenetriol 176.17
BXGC0005502 Coumestrol 268.22
BXGC0005659 Arachidonic acid 304.47
BXGC0005682 3,3',4,4'-Tetrahydroxylignan 302.36
BXGC0005683 Quercetin 302.24
BXGC0005793 Baicalein 270.24
BXGC0005867 Serotonin 176.22
BXGC0005869 Riboflavine 376.36
BXGC0005871 Dopamine 153.18
BXGC0005919 Biochanin A 284.27
BXGC0006107 alpha-Linolenic acid 278.43
BXGC0006193 Ellagic acid 302.19
BXGC0006212 Hypericin 504.44
BXGC0006291 Scopoletin 192.17
BXGC0006306 Myricetin 318.24
BXGC0006389 Rotenone 394.42
BXGC0006635 Luteolin 286.24
BXGC0007035 Cryptotanshinone 296.36
BXGC0007601 1,8-Cineole 154.25
BXGC0008184 Phloretin 274.27
BXGC0008912 Panasenoside 610.52
BXGC0008943 Kaempferol 3-robinobioside 594.52
BXGC0010010 3,8''-Biapigenin 538.46
BXGC0011207 (R)-Bitalin A 218.25
BXGC0011280 Isothymonin 360.31
BXGC0011421 3-Hydroxy-1-(4-hydroxyphenyl)-1-propanone 166.17
BXGC0011887 (3S,5R,6S,7E,9x)-7-Megastigmene-3,6,9-triol 9-glucoside 390.47
BXGC0012704 Dibromoacetic Acid 215.84
BXGC0012728 fucoxanthin 658.42
BXGC0013265 retrorsine 351.17
BXGC0014262 O-Acetylursolic Acid 498.37
BXGC0014934 L-Norepinephrine 169.07
BXGC0015884 Docusate 422.23
BXGC0016421 punicalin 782.06
BXGC0016681 Hispidin 246.05
BXGC0016687 4-[(E)-3-Hydroxyprop-1-Enyl]Benzene-1,2-Diol 166.06
BXGC0017701 Altenusin 290.08
BXGC0017933 Sulfuretin 270.05
BXGC0018287 Erythrosine 835.66
BXGC0018736 Benzamide 121.05
BXGC0018843 Quinalizarin 272.03
BXGC0019164 Raloxifene 473.17
BXGC0020344 Icosa-5,8,11,14-Tetraynoic Acid 296.18
BXGC0020654 Dopa 197.07
BXGC0021893 Norepinephrine 169.07
BXGC0022485 Heracleninprangenin 286.08
BXGC0022544 Digoxin 780.43
BXGC0023917 Cearoin 244.07
BXGC0024915 Dehydroglaucine 353.16
BXGC0025323 Senecionine 335.17
BXGC0025653 Koparin 300.06
BXGC0025757 Calcimycin 523.27
BXGC0026440 Besigomsin 416.18
BXGC0026658 (E)-3-Phenyl-N-(2-Phenylethyl)Prop-2-Enamide 251.13
BXGC0027421 Paclitaxel 853.33
BXGC0028001 Beta-Lapachone 242.09
BXGC0028058 Isoboldine 327.15
BXGC0028589 5,6,7,8-Tetrahydroxy-2-(4-Hydroxyphenyl)Chromen-4-One 302.04
BXGC0030197 Prostaglandin B1 336.23
BXGC0031384 Epinephrine 183.09
BXGC0031717 Purpurin 256.04
BXGC0032798 Shikonin 288.1
BXGC0033112 Acetylcysteine 163.03
BXGC0033310 Epigalocatechin Gallate 458.08
BXGC0033592 (3S,3As,5Ar,9R,9As,9Bs)-9-Hydroxy-3,5A,9-Trimethyl-3,3A,4,5,9A,9B-Hexahydrobenzo[G][1]Benzofuran-2,6-Dione 264.14
BXGC0034256 Rottlerin 516.18
BXGC0034712 (2R,3S)-2-(3,4-Dihydroxyphenyl)-3,5,7-Trihydroxy-2,3-Dihydrochromen-4-One 304.06
BXGC0036362 Sodium Lauryl Sulfate 265.15
BXGC0036918 5-Hydroxy-2-(4-Hydroxy-3,5-Dimethoxyphenyl)-6,7-Dimethoxychromen-4-One 374.1
BXGC0037599 Tanshinone Iia 294.13
BXGC0037718 Ethacrynic Acid 302.01
BXGC0038546 [(3Ar,4S,6Z,9E,11S,11Ar)-11-Hydroxy-6,10-Dimethyl-3-Methylidene-2,8-Dioxo-4,5,11,11A-Tetrahydro-3Ah-Cyclodeca[B]Furan-4-Yl] 2-Methylprop-2-Enoate 346.14
BXGC0038719 1,6-Dimethyl-1,2-Dihydronaphtho[1,2-G][1]Benzofuran-10,11-Dione 278.09
BXGC0038895 Emodic Acid 300.03
BXGC0039397 Athraquinones A 240.04
BXGC0040358 Lobaric Acid 456.18
BXGC0040936 Sid26657808 284.07
BXGC0042091 Dequalinium 456.33
BXGC0042397 5,7-Dihydroxy-2-(4-Hydroxyphenyl)-6-Methyl-2,3-Dihydrochromen-4-One 286.08
BXGC0043125 Taxifolin 304.06
BXGC0043712 3,3'-di-O-methylellagic acid 330.04
BXGC0044285 Hematoxylin 302.08
BXGC0046548 Seneciphyllin 333.16
BXGC0047088 Ursolic Acid 456.36
BXGC0048043 6,10-Dimethyl-3-Methylidene-3A,4,5,8,9,11A-Hexahydrocyclodeca[B]Furan-2-One 232.15
BXGC0048313 Rosmarinic Acid 360.08
BXGC0048348 Guanosine 283.09
BXGC0048389 Catechin 290.08
BXGC0048395 (2R)-2-(3,4-Dihydroxyphenyl)-3,5,7-Trihydroxy-2,3-Dihydrochromen-4-One 304.06
BXGC0048801 Sid24823998 254.09
BXGC0049858 Chalcone 208.09
BXGC0050184 Myricitrin 464.1
BXGC0050332 Robinetin 302.04
BXGC0050651 Cryptotanshinone 296.14
BXGC0050724 2-(3,4-Dihydroxyphenyl)-5-Hydroxy-7-[(2R,3R,4S,5S,6R)-3,4,5-Trihydroxy-6-(Hydroxymethyl)Oxan-2-Yl]Oxychromen-4-One 448.1
BXGC0050823 Chebulinic acid 956.11
BXGC0051756 [8,8-Dimethyl-9-[(Z)-2-Methylbut-2-Enoyl]Oxy-2-Oxo-9,10-Dihydropyrano[2,3-F]Chromen-10-Yl] (Z)-2-Methylbut-2-Enoate 426.17
BXGC0051995 Wedelolactone 314.04
BXGC0052052 (2E)-2-[(3,4-Dihydroxyphenyl)Methylidene]-6-Hydroxy-1-Benzofuran-3-One 270.05
BXGC0052081 n.a 284.07
BXGC0052355 [5,7-Dihydroxy-2-(3,4,5-Trihydroxyphenyl)-3,4-Dihydro-2H-Chromen-3-Yl] 3,4,5-Trihydroxybenzoate 458.08
The  target protein-related  foods
Foods
BXGF Id Food Name Scientific Name Food Group Number of compound? Number of compound in food, higher numbers indicate the food are more associated with the protein