acompound

General Compound Information
BXGC Id	BXGC0026249
Compound Name	Naramycin B
Structure
Formula	C15H23NO4
InchiKey	YPHMISFOHDHNIV-GAIPPQHRSA-N
SMILES	C[C@H]1C[C@H](C)C(=O)[C@H](C1)[C@@H](CC1CC(=NC(=O)C1)O)O
Inchi	InChI=1S/C15H23NO4/c1-8-3-9(2)15(20)11(4-8)12(17)5-10-6-13(18)16-14(19)7-10/h8-12,17H,3-7H2,1-2H3,(H,16,18,19)/t8-,9-,11+,12+/m0/s1
IUPAC	4-[(2R)-2-[(1R,3S,5S)-3,5-dimethyl-2-oxocyclohexyl]-2-hydroxyethyl]piperidine-2,6-dione
Molecular Weight	281.16
Pubchem Id	120760
Chembl Id	CHEMBL1078564

Targets of Information Source

DrugBank

n.a

Uniport Id	BXGT Id	Protein Name	Status	Protein Class	Gene	Groups	Target Type
Uniport Id	BXGT Id	Protein Name	Status	Protein Class	Gene	Groups	Target Type

PDB

n.a

Uniport Id	BXGT Id	Protein Name	Status	Protein Class	Gene	Ki nM	ic50 nM	Kd nM	Ka M-1
Uniport Id	BXGT Id	Protein Name	Status	Protein Class	Gene	Ki nM	ic50 nM	Kd nM	Ka M-1

Binding DB

n.a

Uniport Id	BXGT Id	Protein Name	Status	Protein Class	Gene	Ki nM	ic50 nM	Kd nM	EC50 nM
Uniport Id	BXGT Id	Protein Name	Status	Protein Class	Gene	Ki nM	ic50 nM	Kd nM	EC50 nM

CHEMBL

Uniport Id	BXGT Id	Protein Name	Status	Protein Class	Gene	width="10%">Type	Relation	value	Units
Uniport Id	BXGT Id	Protein Name	Status	Protein Class	Gene	Type	Relation	value	Units
P49841	BXGT010750	Glycogen synthase kinase-3 beta	reviewed	Kinase	GSK3B	IZ	-	-	-
P33261	BXGT009707	Cytochrome P450 2C19	reviewed	-	CYP2C19	Potency	'='	15848	nM
P49841	BXGT010750	Glycogen synthase kinase-3 beta	reviewed	Kinase	GSK3B	IZ	'='	12	mm
P49841	BXGT010750	Glycogen synthase kinase-3 beta	reviewed	Kinase	GSK3B	IZ	'='	25	mm
P10635	BXGT007595	Cytochrome P450 2D6	reviewed	-	CYP2D6	AC50	-	-	-
Q9NUW8	BXGT021219	Tyrosyl-DNA phosphodiesterase 1	reviewed	Enzyme	TDP1	Potency	-	84	nM
P51450	BXGT010847	Nuclear receptor ROR-gamma	reviewed	-	Rorc	Potency	'='	100	nM
P33261	BXGT009707	Cytochrome P450 2C19	reviewed	-	CYP2C19	AC50	'='	15848	nM
P05177	BXGT006336	Cytochrome P450 1A2	reviewed	Enzyme	CYP1A2	AC50	'='	39810	nM
P08684	BXGT006812	Cytochrome P450 3A4	reviewed	Enzyme	CYP3A4	AC50	-	-	-
P49841	BXGT010750	Glycogen synthase kinase-3 beta	reviewed	Kinase	GSK3B	IZ	'='	22	mm
P49841	BXGT010750	Glycogen synthase kinase-3 beta	reviewed	Kinase	GSK3B	IZ	'='	16	mm
P49841	BXGT010750	Glycogen synthase kinase-3 beta	reviewed	Kinase	GSK3B	IZ	'='	33	mm
Q9NUW8	BXGT021219	Tyrosyl-DNA phosphodiesterase 1	reviewed	Enzyme	TDP1	Potency	-	133	nM
P15917	BXGT008169	Lethal factor	reviewed	-	lef	Potency	'='	199	nM
P15917	BXGT008169	Lethal factor	reviewed	-	lef	Potency	'='	125	nM
P11712	BXGT007738	Cytochrome P450 2C9	reviewed	-	CYP2C9	AC50	-	-	-
P49841	BXGT010750	Glycogen synthase kinase-3 beta	reviewed	Kinase	GSK3B	IZ	'='	15	mm
P51450	BXGT010847	Nuclear receptor ROR-gamma	reviewed	-	Rorc	Potency	'='	28183	nM

Foods containing the compound

Foods

BXGF Id	Food Name	Scientific Name	Food Group
BXGF Id	Food Name	Scientific Name	Food Group
BXGF01352	Malva crispa	Malva crispa	Human Edible Plant
BXGF01393	Croton californicus	Croton californicus	Others
BXGF01407	Solanum toxicarium	Solanum toxicarium	Others
BXGF01995	Ratibida latipalearis	Ratibida latipalearis	Medicinal Plant
BXGF02666	Culcitium canescens	Culcitium canescens	Others
BXGF02876	Andropogon nardus	Andropogon nardus	Medicinal Plant
BXGF03866	Toxicodendron succedaneum	Toxicodendron succedaneum	Medicinal Plant
BXGF05016	Nolina erumpens	Nolina erumpens	Others
BXGF05063	Aglaia gigantea	Aglaia gigantea	Others
BXGF05419	Dendrobium rotundatum	Dendrobium rotundatum	Others
BXGF05719	Neoalsomitra integrifolia	Neoalsomitra integrifolia	Others
BXGF05815	Espeletia marcana	Espeletia marcana	Others
BXGF05830	Clibadium pentaneuron	Clibadium pentaneuron	Others
BXGF06019	Picrorhiza kurrooa	Picrorhiza kurrooa	Medicinal Plant
BXGF06047	Petasites niveus	Petasites niveus	Others
BXGF06133	Eriostemon fitzgeraldii	Eriostemon fitzgeraldii	Others
BXGF06196	Weddellina squamulosa	Weddellina squamulosa	Others
BXGF06258	Croton sparsiflorus	Croton sparsiflorus	Medicinal Plant
BXGF06313	Piptolepis leptospermoides	Piptolepis leptospermoides	Others

The compound-realted diseases

Diseases

BXGD Id	Disease Name	CUI Disease Id	Disease Class Name	Number of targets^{?Number of targets related to compound connecting disease, higher numbers indicate the compound is more associated with the disease}