acompound

Showing entry for 3-(3,4-Dihydroxyphenyl)-7-Hydroxychromen-4-One

General Compound Information
BXGC Id	BXGC0032283
Compound Name	3-(3,4-Dihydroxyphenyl)-7-Hydroxychromen-4-One
Structure
Formula	C15H10O5
InchiKey	DDKGKOOLFLYZDL-UHFFFAOYSA-N
SMILES	Oc1ccc2c(c1)occ(c2=O)c1ccc(c(c1)O)O
Inchi	InChI=1S/C15H10O5/c16-9-2-3-10-14(6-9)20-7-11(15(10)19)8-1-4-12(17)13(18)5-8/h1-7,16-18H
IUPAC	3-(3,4-dihydroxyphenyl)-7-hydroxychromen-4-one
Molecular Weight	270.05
Pubchem Id	5284648
Chembl Id	CHEMBL13486

Targets of Information Source

DrugBank

n.a

Uniport Id	BXGT Id	Protein Name	Status	Protein Class	Gene	Groups	Target Type
Uniport Id	BXGT Id	Protein Name	Status	Protein Class	Gene	Groups	Target Type

PDB

47X

Uniport Id	BXGT Id	Protein Name	Status	Protein Class	Gene	Ki nM	ic50 nM	Kd nM	Ka M-1
Uniport Id	BXGT Id	Protein Name	Status	Protein Class	Gene	Ki nM	ic50 nM	Kd nM	Ka M-1
P14174	BXGT007991	Macrophage migration inhibitory factor	reviewed	MIF	-	-	38	-	-
P53355	BXGT010985	Death-associated protein kinase 1	reviewed	DAPK1	Kinase	-	280000	-	-

Binding DB

50095997

Uniport Id	BXGT Id	Protein Name	Status	Protein Class	Gene	Ki nM	ic50 nM	Kd nM	EC50 nM
Uniport Id	BXGT Id	Protein Name	Status	Protein Class	Gene	Ki nM	ic50 nM	Kd nM	EC50 nM
reviewed	BXGT010985	Death-associated protein kinase 1	reviewed	Kinase	DAPK1	-	280000	-	-
reviewed	BXGT010602	Xanthine dehydrogenase/oxidase	reviewed	Enzyme	XDH	-	16800	-	-
reviewed	BXGT010602	Xanthine dehydrogenase/oxidase	reviewed	Enzyme	XDH	-	>1000000	-	-
reviewed	BXGT007991	Macrophage migration inhibitory factor	reviewed		MIF	38	-	-	-
reviewed	BXGT007991	Macrophage migration inhibitory factor	reviewed		MIF	-	38	-	-
reviewed	BXGT007991	Macrophage migration inhibitory factor	reviewed		MIF	15000	-	-	-
reviewed	BXGT007687	Tyrosinase	reviewed		Tyr	-	5230	-	-

CHEMBL

CHEMBL13486

Uniport Id	BXGT Id	Protein Name	Status	Protein Class	Gene	width="10%">Type	Relation	value	Units
Uniport Id	BXGT Id	Protein Name	Status	Protein Class	Gene	Type	Relation	value	Units
P14174	BXGT007991	Macrophage migration inhibitory factor	reviewed	-	MIF	IC50	'='	38	nM
P14174	BXGT007991	Macrophage migration inhibitory factor	reviewed	-	MIF	Ki	'='	38	nM
P11344	BXGT007687	Tyrosinase	reviewed	-	Tyr	IC50	'='	5230	nM
P11388	BXGT007697	DNA topoisomerase 2-alpha	reviewed	-	TOP2A	Activity	-	-	-
P47989	BXGT010602	Xanthine dehydrogenase/oxidase	reviewed	Enzyme	XDH	IC50	'>'	1000000	nM
P14174	BXGT007991	Macrophage migration inhibitory factor	reviewed	-	MIF	Ki	'='	15000	nM
P47989	BXGT010602	Xanthine dehydrogenase/oxidase	reviewed	Enzyme	XDH	IC50	'='	16800	nM
P37231	BXGT009972	Peroxisome proliferator-activated receptor gamma	reviewed	Nuclear receptor	PPARG	FC	'='	1	-
P37231	BXGT009972	Peroxisome proliferator-activated receptor gamma	reviewed	Nuclear receptor	PPARG	FC	'='	7	-
P18031	BXGT008369	Tyrosine-protein phosphatase non-receptor type 1	reviewed	-	PTPN1	Inhibition	'='	28	%
P53355	BXGT010985	Death-associated protein kinase 1	reviewed	Kinase	DAPK1	IC50	'='	280000	nM

Foods containing the compound

Foods

BXGF Id	Food Name	Scientific Name	Food Group
BXGF Id	Food Name	Scientific Name	Food Group
BXGF01168	Erysimum leptophyllum	Erysimum leptophyllum	Others
BXGF01295	Chondrodendron tomentosum	Chondrodendron tomentosum	Medicinal Plant
BXGF01354	Haplophyllum obtusifolium	Haplophyllum obtusifolium	Others
BXGF01373	Myroxylon peruiferum	Myroxylon peruiferum	Others
BXGF01621	Syzygium polycephaloides	Syzygium polycephaloides	Human Edible Plant
BXGF02202	Piper regnellii	Piper regnellii	Medicinal Plant
BXGF02287	Gymnocalycium schickendantzii	Gymnocalycium schickendantzii	Others
BXGF02445	Onopordum acanthium	Onopordum acanthium	Medicinal Plant
BXGF02500	Pancratium sickenbergeri	Pancratium sickenbergeri	Others
BXGF02573	Centaurea maculosa	Centaurea maculosa	Others
BXGF02626	Dalbergia odorifera	Dalbergia odorifera	Medicinal Plant
BXGF02635	Ephedra sinica	Ephedra sinica	Medicinal Plant
BXGF02695	Plathymenia reticulata	Plathymenia reticulata	Others
BXGF02729	Asimina parviflora	Asimina parviflora	Medicinal Plant
BXGF02774	Pteridium esculentum	Pteridium esculentum	Medicinal Plant
BXGF02813	Esenbeckia leiocarpa	Esenbeckia leiocarpa	Others
BXGF02852	Sophora flavescens	Sophora flavescens	Medicinal Plant
BXGF02929	Hypericum styphelioides	Hypericum styphelioides	Others
BXGF02973	Vellozia nanuzae	Vellozia nanuzae	Others
BXGF02992	Baccharis neglecta	Baccharis neglecta	Others
BXGF03012	Atraphaxis spinosa	Atraphaxis spinosa	Medicinal Plant
BXGF03027	Embelia schimperi	Embelia schimperi	Medicinal Plant
BXGF03087	Epilobium hirsutum	Epilobium hirsutum	Medicinal Plant
BXGF03106	Lythrum salicaria	Lythrum salicaria	Medicinal Plant
BXGF03113	Simarouba glauca	Simarouba glauca	Medicinal Plant
BXGF03126	Erythrina melanacantha	Erythrina melanacantha	Medicinal Plant
BXGF03151	Monsonia senegalensis	Monsonia senegalensis	Human Edible Plant
BXGF03157	Clerodendrum bungei	Clerodendrum bungei	Medicinal Plant
BXGF03186	Lemaireocereus longispinus	Lemaireocereus longispinus	Others
BXGF03197	Eria anomala	Eria anomala	Others
BXGF03208	Embelia parviflora	Embelia parviflora	Medicinal Plant
BXGF03250	Euphorbia nematocypha	Euphorbia nematocypha	Medicinal Plant
BXGF03279	Abelia chinensis	Abelia chinensis	Unclassified
BXGF03297	Diospyros assimilis	Diospyros assimilis	Medicinal Plant
BXGF03310	Faramea salicifolia	Faramea salicifolia	Others
BXGF03564	Vernonia fagifolia	Vernonia fagifolia	Others
BXGF03570	Cordia leucocephala	Cordia leucocephala	Others
BXGF04584	Helichrysum tenuifolium	Helichrysum tenuifolium	Others
BXGF05010	Morella rubra	Morella rubra	0
BXGF06079	Pueraria montana var. lobata	Pueraria montana var. lobata	Medicinal Plant

The compound-realted diseases

Diseases

BXGD Id	Disease Name	CUI Disease Id	Disease Class Name	Number of targets^{?Number of targets related to compound connecting disease, higher numbers indicate the compound is more associated with the disease}