Showing entry for DNA topoisomerase 2-alpha


　 　 　 　 　 　 　 　 　 　 　 　
General Target Information
BXGT IdBXGT007697
Protein NameDNA topoisomerase 2-alpha
Uniport IdP11388
GeneTOP2A
Gene Id7153
DomainDNA_gyraseB; DNA_topoisoIV; DTHCT; HATPase_c; Toprim; TOPRIM_C
Pfam PF00204   PF00521   PF08070   PF02518   PF01751   PF16898  
OrganismHomo sapiens (Human)
Target protein  affiliated  biological  pathways
KEGG
Class Subclass KEGG Id Pathway Name
6. Human Diseases 6.12 Drug resistance: Antineoplastic hsa01524 Platinum drug resistance
Gene Ontology
GO Type GO Id Gene Ontology
Biological Process GO:0030263 apoptotic chromosome condensation
Biological Process GO:0006974 cellular response to DNA damage stimulus
Biological Process GO:0007059 chromosome segregation
Biological Process GO:0006266 DNA ligation
Biological Process GO:0006265 DNA topological change
Biological Process GO:0040016 embryonic cleavage
Biological Process GO:0007143 female meiotic nuclear division
Biological Process GO:0002244 hematopoietic progenitor cell differentiation
Biological Process GO:0044774 mitotic DNA integrity checkpoint
Biological Process GO:1905463 negative regulation of DNA duplex unwinding
Biological Process GO:0043065 positive regulation of apoptotic process
Biological Process GO:0045870 positive regulation of single stranded viral RNA replication via double stranded DNA intermediate
Biological Process GO:0045944 positive regulation of transcription by RNA polymerase II
Biological Process GO:0042752 regulation of circadian rhythm
Biological Process GO:0000712 resolution of meiotic recombination intermediates
Biological Process GO:0048511 rhythmic process
Biological Process GO:0000819 sister chromatid segregation
molecular function GO:0005524 ATP binding
molecular function GO:0003682 chromatin binding
molecular function GO:0003677 DNA binding
molecular function GO:0008301 DNA binding, bending
molecular function GO:0008094 DNA-dependent ATPase activity
molecular function GO:0003918 DNA topoisomerase type II (double strand cut, ATP-hydrolyzing) activity
molecular function GO:0008144 drug binding
molecular function GO:0019899 enzyme binding
molecular function GO:0042826 histone deacetylase binding
molecular function GO:0000287 magnesium ion binding
molecular function GO:0008022 protein C-terminus binding
molecular function GO:0046982 protein heterodimerization activity
molecular function GO:0042803 protein homodimerization activity
molecular function GO:0005080 protein kinase C binding
molecular function GO:0003723 RNA binding
molecular function GO:0043130 ubiquitin binding
cellular component GO:0000775 chromosome, centromeric region
cellular component GO:0000793 condensed chromosome
cellular component GO:0005737 cytoplasm
cellular component GO:0009330 DNA topoisomerase type II (double strand cut, ATP-hydrolyzing) complex
cellular component GO:0005730 nucleolus
cellular component GO:0005654 nucleoplasm
cellular component GO:0005634 nucleus
cellular component GO:0032991 protein-containing complex
cellular component GO:1990904 ribonucleoprotein complex
cellular component GO:0019035 viral integration complex
Reactome
Pathway Id Pathway Name
R-HSA-1362277 Transcription of E2F targets under negative control by DREAM complex
R-HSA-1538133 G0 and Early G1
R-HSA-1640170 Cell Cycle
R-HSA-2990846 SUMOylation
R-HSA-2990846 SUMOylation
R-HSA-3108232 SUMO E3 ligases SUMOylate target proteins
R-HSA-3108232 SUMO E3 ligases SUMOylate target proteins
R-HSA-392499 Metabolism of proteins
R-HSA-392499 Metabolism of proteins
R-HSA-453279 Mitotic G1 phase and G1/S transition
R-HSA-4615885 SUMOylation of DNA replication proteins
R-HSA-4615885 SUMOylation of DNA replication proteins
R-HSA-597592 Post-translational protein modification
R-HSA-597592 Post-translational protein modification
R-HSA-69278 Cell Cycle, Mitotic
Target protein-related  diseases
Disease
CUI Id BXGD Id Disease Name Disease Class
C0001418 BXGD000050 Adenocarcinoma Neoplasms
C0001618 BXGD000063 Tumors of Adrenal Cortex Neoplasms; Endocrine System Diseases
C0004114 BXGD000255 Astrocytoma Neoplasms
C0004134 BXGD000256 Ataxia Pathological Conditions, Signs and Symptoms; Nervous System Diseases
C0004135 BXGD000257 Ataxia Telangiectasia Congenital, Hereditary, and Neonatal Diseases and Abnormalities; Nutritional and Metabolic Diseases; Immune System Diseases; Nervous System Diseases; Cardiovascular Diseases
C0005684 BXGD000319 Malignant neoplasm of urinary bladder Neoplasms; Female Urogenital Diseases and Pregnancy Complications; Male Urogenital Diseases
C0005695 BXGD000323 Bladder Neoplasm Neoplasms; Female Urogenital Diseases and Pregnancy Complications; Male Urogenital Diseases
C0006142 BXGD000374 Malignant neoplasm of breast Neoplasms; Skin and Connective Tissue Diseases
C0006826 BXGD000408 Malignant Neoplasms Neoplasms
C0007097 BXGD000424 Carcinoma Neoplasms
C0007102 BXGD000425 Malignant tumor of colon Digestive System Diseases; Neoplasms
C0007104 BXGD000427 Female Breast Carcinoma Neoplasms; Skin and Connective Tissue Diseases
C0007124 BXGD000437 Noninfiltrating Intraductal Carcinoma Neoplasms
C0007131 BXGD000441 Non-Small Cell Lung Carcinoma Neoplasms; Respiratory Tract Diseases
C0007137 BXGD000445 Squamous cell carcinoma Neoplasms
C0007758 BXGD000475 Cerebellar Ataxia Pathological Conditions, Signs and Symptoms; Nervous System Diseases
C0007873 BXGD000500 Uterine Cervical Neoplasm Neoplasms; Female Urogenital Diseases and Pregnancy Complications
C0009375 BXGD000602 Colonic Neoplasms Digestive System Diseases; Neoplasms
C0009402 BXGD000605 Colorectal Carcinoma Digestive System Diseases; Neoplasms
C0009404 BXGD000606 Colorectal Neoplasms Digestive System Diseases; Neoplasms
C0010276 BXGD000659 Craniopharyngioma Neoplasms
C0010606 BXGD000677 Adenoid Cystic Carcinoma Neoplasms
C0010823 BXGD000690 Cytomegalovirus Infections Infections
C0011860 BXGD000755 Diabetes Mellitus, Non-Insulin-Dependent Nutritional and Metabolic Diseases; Endocrine System Diseases
C0011991 BXGD000766 Diarrhea Pathological Conditions, Signs and Symptoms
C0013371 BXGD000823 Shigella Infections Digestive System Diseases; Infections
C0016048 BXGD001038 Fibromatosis Neoplasms
C0016978 BXGD001087 gallbladder neoplasm Digestive System Diseases; Neoplasms
C0017636 BXGD001131 Glioblastoma Neoplasms
C0017638 BXGD001132 Glioma Neoplasms
C0019163 BXGD001295 Hepatitis B Digestive System Diseases; Infections
C0019196 BXGD001301 Hepatitis C Digestive System Diseases; Infections
C0019348 BXGD001325 Herpes Simplex Infections Infections; Skin and Connective Tissue Diseases
C0019829 BXGD001350 Hodgkin Disease Neoplasms; Immune System Diseases; Hemic and Lymphatic Diseases
C0023269 BXGD001627 leiomyosarcoma Neoplasms
C0023343 BXGD001635 Leprosy Infections
C0023418 BXGD001642 leukemia Neoplasms
C0023449 BXGD001650 Acute lymphocytic leukemia Neoplasms; Immune System Diseases; Hemic and Lymphatic Diseases
C0023452 BXGD001651 Childhood Acute Lymphoblastic Leukemia Neoplasms; Immune System Diseases; Hemic and Lymphatic Diseases
C0023467 BXGD001658 Leukemia, Myelocytic, Acute Neoplasms
C0023827 BXGD001707 liposarcoma Neoplasms
C0023903 BXGD001720 Liver neoplasms Digestive System Diseases; Neoplasms
C0024299 BXGD001758 Lymphoma Neoplasms; Immune System Diseases; Hemic and Lymphatic Diseases
C0024623 BXGD001791 Malignant neoplasm of stomach Digestive System Diseases; Neoplasms
C0025149 BXGD001826 Medulloblastoma Neoplasms
C0025202 BXGD001832 melanoma Neoplasms
C0025286 BXGD001850 Meningioma Neoplasms; Nervous System Diseases
C0026499 BXGD001905 Monosomy Pathological Conditions, Signs and Symptoms
C0026936 BXGD001950 Mycoplasma Infections Infections
C0027627 BXGD002006 Neoplasm Metastasis Pathological Conditions, Signs and Symptoms; Neoplasms
C0027651 BXGD002009 Neoplasms Neoplasms
C0027708 BXGD002025 Nephroblastoma Congenital, Hereditary, and Neonatal Diseases and Abnormalities; Neoplasms; Female Urogenital Diseases and Pregnancy Complications; Male Urogenital Diseases
C0027766 BXGD002034 Nervous System Neoplasms Neoplasms; Nervous System Diseases
C0027819 BXGD002043 Neuroblastoma Neoplasms
C0027830 BXGD002046 neurofibroma Neoplasms; Nervous System Diseases
C0027831 BXGD002047 Neurofibromatosis 1 Congenital, Hereditary, and Neonatal Diseases and Abnormalities; Neoplasms; Nervous System Diseases
C0032019 BXGD002321 Pituitary Neoplasms Neoplasms; Nervous System Diseases; Endocrine System Diseases
C0032460 BXGD002355 Polycystic Ovary Syndrome Neoplasms; Female Urogenital Diseases and Pregnancy Complications; Endocrine System Diseases
C0033578 BXGD002408 Prostatic Neoplasms Neoplasms; Male Urogenital Diseases
C0033822 BXGD002430 Pseudomyxoma Peritonei Neoplasms
C0035222 BXGD002513 Respiratory Distress Syndrome, Adult Respiratory Tract Diseases
C0036095 BXGD002576 Salivary Gland Neoplasms Neoplasms; Stomatognathic Diseases
C0036690 BXGD002632 Septicemia Pathological Conditions, Signs and Symptoms; Infections
C0038356 BXGD002747 Stomach Neoplasms Digestive System Diseases; Neoplasms
C0041296 BXGD002903 Tuberculosis Infections
C0042029 BXGD002951 Urinary tract infection Female Urogenital Diseases and Pregnancy Complications; Infections; Male Urogenital Diseases
C0079588 BXGD003084 Ichthyosis, X-Linked Congenital, Hereditary, and Neonatal Diseases and Abnormalities; Nutritional and Metabolic Diseases; Skin and Connective Tissue Diseases
C0079744 BXGD003090 Diffuse Large B-Cell Lymphoma Neoplasms; Immune System Diseases; Hemic and Lymphatic Diseases
C0085669 BXGD003233 Acute leukemia Pathological Conditions, Signs and Symptoms; Neoplasms
C0086692 BXGD003306 Benign Neoplasm Neoplasms
C0149782 BXGD003365 Squamous cell carcinoma of lung Neoplasms; Respiratory Tract Diseases
C0149925 BXGD003387 Small cell carcinoma of lung Neoplasms; Respiratory Tract Diseases
C0151779 BXGD003473 Cutaneous Melanoma Neoplasms; Skin and Connective Tissue Diseases
C0152013 BXGD003516 Adenocarcinoma of lung (disorder) Neoplasms
C0152451 BXGD003597 Chronic glomerulonephritis Female Urogenital Diseases and Pregnancy Complications; Male Urogenital Diseases
C0162678 BXGD003974 Neurofibromatoses Congenital, Hereditary, and Neonatal Diseases and Abnormalities; Neoplasms; Nervous System Diseases
C0175754 BXGD004015 Agenesis of corpus callosum Pathological Conditions, Signs and Symptoms; Congenital, Hereditary, and Neonatal Diseases and Abnormalities; Nervous System Diseases
C0178874 BXGD004037 Tumor Progression Pathological Conditions, Signs and Symptoms
C0206139 BXGD004159 Lichen Planus, Oral Skin and Connective Tissue Diseases; Stomatognathic Diseases
C0206526 BXGD004180 Tuberculosis, Multidrug-Resistant Infections
C0206686 BXGD004241 Adrenocortical carcinoma Neoplasms; Endocrine System Diseases
C0206715 BXGD004261 Neoplasms, Neuroepithelial Neoplasms
C0206728 BXGD004273 Plexiform Neurofibroma Neoplasms; Nervous System Diseases
C0220636 BXGD004304 Malignant neoplasm of salivary gland Neoplasms; Stomatognathic Diseases
C0220650 BXGD004310 Metastatic malignant neoplasm to brain Pathological Conditions, Signs and Symptoms; Neoplasms; Nervous System Diseases
C0235874 BXGD004781 Disease Exacerbation Pathological Conditions, Signs and Symptoms
C0235974 BXGD004796 Pancreatic carcinoma Digestive System Diseases; Neoplasms; Endocrine System Diseases
C0238198 BXGD004893 Gastrointestinal Stromal Tumors Digestive System Diseases; Neoplasms
C0238463 BXGD004938 Papillary thyroid carcinoma Neoplasms; Endocrine System Diseases
C0241577 BXGD005102 Elevated urinary catecholamines
C0242379 BXGD005157 Malignant neoplasm of lung Neoplasms; Respiratory Tract Diseases
C0243026 BXGD005210 Sepsis Pathological Conditions, Signs and Symptoms; Infections
C0259783 BXGD005221 mixed gliomas Neoplasms
C0262655 BXGD005264 Recurrent urinary tract infection Female Urogenital Diseases and Pregnancy Complications; Infections; Male Urogenital Diseases
C0265987 BXGD005598 Nevus comedonicus Congenital, Hereditary, and Neonatal Diseases and Abnormalities; Neoplasms; Skin and Connective Tissue Diseases
C0278493 BXGD006517 Breast cancer recurrent Neoplasms; Skin and Connective Tissue Diseases
C0278510 BXGD006526 Childhood Medulloblastoma Neoplasms
C0278607 BXGD006548 Adult Leiomyosarcoma Neoplasms
C0278701 BXGD006566 Gastric Adenocarcinoma Digestive System Diseases; Neoplasms
C0278876 BXGD006607 Adult Medulloblastoma Neoplasms
C0278877 BXGD006608 Adult Meningioma Neoplasms; Nervous System Diseases
C0278878 BXGD006609 Adult Glioblastoma Neoplasms
C0279637 BXGD006665 Anal carcinoma Digestive System Diseases; Neoplasms
C0279680 BXGD006680 Transitional cell carcinoma of bladder Neoplasms; Female Urogenital Diseases and Pregnancy Complications; Male Urogenital Diseases
C0279702 BXGD006685 Conventional (Clear Cell) Renal Cell Carcinoma Neoplasms; Female Urogenital Diseases and Pregnancy Complications; Male Urogenital Diseases
C0279986 BXGD006705 Childhood Leiomyosarcoma Neoplasms
C0280100 BXGD006713 Solid Neoplasm Neoplasms
C0280324 BXGD006740 Laryngeal Squamous Cell Carcinoma Neoplasms; Respiratory Tract Diseases; Otorhinolaryngologic Diseases
C0280474 BXGD006748 Childhood Glioblastoma Neoplasms
C0280631 BXGD006752 Leiomyosarcoma of uterus Neoplasms; Female Urogenital Diseases and Pregnancy Complications
C0281361 BXGD006774 Adenocarcinoma of pancreas Digestive System Diseases; Neoplasms; Endocrine System Diseases
C0282160 BXGD006797 Aplasia Cutis Congenita Congenital, Hereditary, and Neonatal Diseases and Abnormalities; Skin and Connective Tissue Diseases
C0282606 BXGD006817 Myomatous neoplasm Neoplasms; Musculoskeletal Diseases
C0333875 BXGD006972 High-Grade Squamous Intraepithelial Lesions Pathological Conditions, Signs and Symptoms; Neoplasms; Female Urogenital Diseases and Pregnancy Complications
C0334579 BXGD007120 Anaplastic astrocytoma Neoplasms
C0334634 BXGD007144 Malignant lymphoma, lymphocytic, intermediate differentiation, diffuse Neoplasms; Immune System Diseases; Hemic and Lymphatic Diseases
C0341439 BXGD007408 Chronic liver disease Digestive System Diseases
C0343401 BXGD007623 MRSA - Methicillin resistant Staphylococcus aureus infection Infections
C0345904 BXGD007745 Malignant neoplasm of liver Digestive System Diseases; Neoplasms
C0346647 BXGD007832 Malignant neoplasm of pancreas Digestive System Diseases; Neoplasms; Endocrine System Diseases
C0349534 BXGD007919 Carcinoma of anal margin Digestive System Diseases; Neoplasms
C0376358 BXGD007992 Malignant neoplasm of prostate Neoplasms; Male Urogenital Diseases
C0376545 BXGD008002 Hematologic Neoplasms Neoplasms; Hemic and Lymphatic Diseases
C0521158 BXGD009130 Recurrent tumor
C0555198 BXGD009432 Malignant Glioma Neoplasms
C0562350 BXGD009476 Hip circumference
C0596263 BXGD009639 Carcinogenesis Pathological Conditions, Signs and Symptoms; Neoplasms
C0600139 BXGD009695 Prostate carcinoma Neoplasms; Male Urogenital Diseases
C0677886 BXGD009734 Epithelial ovarian cancer Neoplasms; Female Urogenital Diseases and Pregnancy Complications; Endocrine System Diseases
C0678222 BXGD009749 Breast Carcinoma Neoplasms; Skin and Connective Tissue Diseases
C0679427 BXGD009777 myeloblastosis Pathological Conditions, Signs and Symptoms; Hemic and Lymphatic Diseases
C0684249 BXGD009790 Carcinoma of lung Neoplasms; Respiratory Tract Diseases
C0699790 BXGD009866 Colon Carcinoma Digestive System Diseases; Neoplasms
C0699791 BXGD009867 Stomach Carcinoma Digestive System Diseases; Neoplasms
C0699885 BXGD009869 Carcinoma of bladder Neoplasms; Female Urogenital Diseases and Pregnancy Complications; Male Urogenital Diseases
C0751606 BXGD010523 Adult Acute Lymphocytic Leukemia
C0751690 BXGD010553 Malignant Peripheral Nerve Sheath Tumor Neoplasms; Nervous System Diseases
C0853879 BXGD010982 Invasive carcinoma of breast Neoplasms; Skin and Connective Tissue Diseases
C0856053 BXGD011091 Leukemia secondary
C0877008 BXGD011325 Enzyme inhibition disorder
C0877015 BXGD011327 Pelvic Organ Prolapse Pathological Conditions, Signs and Symptoms
C0919267 BXGD011426 ovarian neoplasm Neoplasms; Female Urogenital Diseases and Pregnancy Complications; Endocrine System Diseases
C0936223 BXGD011477 Metastatic Prostate Carcinoma Neoplasms; Male Urogenital Diseases
C1136382 BXGD011717 Sclerocystic Ovaries Neoplasms; Female Urogenital Diseases and Pregnancy Complications; Endocrine System Diseases
C1140680 BXGD011718 Malignant neoplasm of ovary Neoplasms; Female Urogenital Diseases and Pregnancy Complications; Endocrine System Diseases
C1257931 BXGD011815 Mammary Neoplasms, Human Neoplasms; Skin and Connective Tissue Diseases
C1261473 BXGD011855 Sarcoma Neoplasms
C1269955 BXGD012005 Tumor Cell Invasion
C1282496 BXGD012147 Metastasis from malignant tumor of prostate
C1306459 BXGD012361 Primary malignant neoplasm Neoplasms
C1306460 BXGD012362 Primary malignant neoplasm of lung Neoplasms; Respiratory Tract Diseases
C1306837 BXGD012377 Papillary Renal Cell Carcinoma Neoplasms; Female Urogenital Diseases and Pregnancy Complications; Male Urogenital Diseases
C1332977 BXGD012569 Childhood Leukemia Neoplasms
C1333015 BXGD012581 Childhood Kidney Wilms Tumor Congenital, Hereditary, and Neonatal Diseases and Abnormalities; Neoplasms; Female Urogenital Diseases and Pregnancy Complications; Male Urogenital Diseases
C1336735 BXGD012856 Treatment related acute myeloid leukaemia
C1458155 BXGD013136 Mammary Neoplasms Neoplasms; Skin and Connective Tissue Diseases
C1512127 BXGD013185 HER2 gene amplification
C1621958 BXGD013468 Glioblastoma Multiforme Neoplasms
C1704272 BXGD013537 Benign Prostatic Hyperplasia Male Urogenital Diseases
C1762616 BXGD013753 Meningioma, benign, no ICD-O subtype Neoplasms; Nervous System Diseases
C1832661 BXGD013866 ANOPHTHALMIA AND PULMONARY HYPOPLASIA Congenital, Hereditary, and Neonatal Diseases and Abnormalities; Eye Diseases; Respiratory Tract Diseases
C1841972 BXGD014484 Glucocorticoid Receptor Deficiency Congenital, Hereditary, and Neonatal Diseases and Abnormalities; Nutritional and Metabolic Diseases
C1851710 BXGD015226 LATERAL MENINGOCELE SYNDROME Pathological Conditions, Signs and Symptoms; Congenital, Hereditary, and Neonatal Diseases and Abnormalities; Nervous System Diseases
C1863753 BXGD016197 LIMB-MAMMARY SYNDROME Congenital, Hereditary, and Neonatal Diseases and Abnormalities; Musculoskeletal Diseases
C1960398 BXGD016658 HER2-positive carcinoma of breast Neoplasms; Skin and Connective Tissue Diseases
C1961102 BXGD016673 Precursor Cell Lymphoblastic Leukemia Lymphoma Neoplasms; Immune System Diseases; Hemic and Lymphatic Diseases
C2239176 BXGD016965 Liver carcinoma Digestive System Diseases; Neoplasms
C2347761 BXGD017049 Childhood Myelodysplastic Syndrome Hemic and Lymphatic Diseases
C2717836 BXGD017510 Steroid Sulfatase Deficiency Disease Congenital, Hereditary, and Neonatal Diseases and Abnormalities; Nutritional and Metabolic Diseases; Skin and Connective Tissue Diseases
C2825306 BXGD017772 Treatment related leukaemia Neoplasms
C2931189 BXGD017972 Neural crest tumor Neoplasms; Endocrine System Diseases
C2931822 BXGD018068 Nasopharyngeal carcinoma Neoplasms; Stomatognathic Diseases; Otorhinolaryngologic Diseases
C2938924 BXGD018167 Oestrogen receptor positive breast cancer
C2939419 BXGD018178 Secondary Neoplasm Pathological Conditions, Signs and Symptoms; Neoplasms
C2986665 BXGD018237 Early-Stage Breast Carcinoma Neoplasms; Skin and Connective Tissue Diseases
C3266262 BXGD018600 Multiple Chronic Conditions Pathological Conditions, Signs and Symptoms
C3463824 BXGD018899 MYELODYSPLASTIC SYNDROME Hemic and Lymphatic Diseases
C3495917 BXGD019012 Advanced breast cancer
C3495949 BXGD019016 Locally advanced breast cancer
C3539878 BXGD019087 Triple Negative Breast Neoplasms Neoplasms; Skin and Connective Tissue Diseases
C3642345 BXGD019244 Luminal A Breast Carcinoma
C3642346 BXGD019245 Luminal B Breast Carcinoma
C3714644 BXGD019422 Thymus Neoplasms Neoplasms; Hemic and Lymphatic Diseases
C3714756 BXGD019429 Intellectual Disability Pathological Conditions, Signs and Symptoms; Nervous System Diseases; Mental Disorders; Behavior and Behavior Mechanisms
C3839280 BXGD019772 High grade serous carcinoma
C3900098 BXGD020106 Adult Myelodysplastic Syndrome Hemic and Lymphatic Diseases
C4048329 BXGD021904 Immunosuppression
C4054726 BXGD021987 Infant Leukemia
C4086152 BXGD022123 Childhood Astrocytoma Neoplasms
C4287589 BXGD022469 Serous Tubal Intraepithelial Carcinoma
C4525546 BXGD023141 Chicken Lymphoma
C4551687 BXGD023392 Sarcoma of soft tissue Neoplasms
C4704874 BXGD023682 Mammary Carcinoma, Human Neoplasms; Skin and Connective Tissue Diseases
C4721209 BXGD023734 Metastatic human epidermal growth factor 2 positive carcinoma of breast Neoplasms; Skin and Connective Tissue Diseases
C4721579 BXGD023759 Secondary malignant neoplasm of colon and/or rectum Digestive System Diseases; Neoplasms
C4721610 BXGD023760 Carcinoma, Ovarian Epithelial Neoplasms; Female Urogenital Diseases and Pregnancy Complications; Endocrine System Diseases
C4722085 BXGD023788 Malignant neoplasm of colon and/or rectum
C4722518 BXGD023806 Triple-Negative Breast Carcinoma Neoplasms; Skin and Connective Tissue Diseases
C4723838 BXGD023809 Metastatic Breast Carcinoma Neoplasms; Skin and Connective Tissue Diseases
C4733095 BXGD023910 HER2-negative breast cancer
Target protein-related  compounds
Compounds
BXGC Id Compound Name Strcuture Molecular Weight
BXGC0000051 Kaempferol 3-O-(2''-rhamnosyl-galactoside) 7-O-rhamnoside 740.66
BXGC0000116 1,4-Naphtoquinone 158.15
BXGC0000332 Fisetin 286.24
BXGC0000340 Kaempferol 286.24
BXGC0000363 Galangin 270.24
BXGC0000436 Glycerol 92.09
BXGC0001837 Quercetin 3-rutinoside 610.52
BXGC0001868 Catechin 290.27
BXGC0001899 Daidzein 254.24
BXGC0002018 Morin 302.24
BXGC0002071 Apigenin 270.24
BXGC0002390 Spermine 202.34
BXGC0002588 Magnesium 24.31
BXGC0003601 Momordin B 632.84
BXGC0003690 Glucokinin 764.94
BXGC0003776 Flavones 222.24
BXGC0004139 Sperminidine 145.25
BXGC0004335 6-Hydroxydaidzein 270.24
BXGC0004378 3-Hydroxyflavone 238.24
BXGC0005559 3',4',5'-Trimethoxyflavone 312.32
BXGC0005624 Genistein 270.24
BXGC0005683 Quercetin 302.24
BXGC0005844 Cholestanol 388.67
BXGC0006066 Prunetin 284.27
BXGC0006213 Psoralen 186.17
BXGC0006306 Myricetin 318.24
BXGC0006466 Oleanolic acid 456.71
BXGC0006635 Luteolin 286.24
BXGC0008184 Phloretin 274.27
BXGC0012763 (5R,5Ar)-5-(4-Hydroxy-3,5-Dimethoxyphenyl)-5A,8,8A,9-Tetrahydro-5H-[2]Benzofuro[5,6-F][1,3]Benzodioxol-6-One 384.12
BXGC0013476 Lauterine 305.07
BXGC0013582 Curcumin 368.13
BXGC0014342 Patentiflorin A 526.15
BXGC0014616 Astragalin 7-rhamnoside 594.16
BXGC0015147 ginsenoside Rg3 784.5
BXGC0015787 Shermilamine C 430.15
BXGC0016470 Camptothecin 348.11
BXGC0016472 Gnf-Pf-349 542.14
BXGC0016675 ginsenoside F3 770.48
BXGC0017269 Mansonone E 242.09
BXGC0019142 ginsenoside Rb3 1078.59
BXGC0019143 Nitidine Chloride 348.12
BXGC0019238 n.a 564.15
BXGC0019342 4'-Demethylpodophyllotoxin 400.12
BXGC0021067 alpha-peltatin 400.12
BXGC0021319 20(S)-Ginsenoside Rg2 784.5
BXGC0021588 Damara-20(22), 24-dien-3, 6, 12-trine 458.38
BXGC0023195 Betulin 442.38
BXGC0023640 Lycorine 287.12
BXGC0024198 oleanderolide 472.36
BXGC0024814 20(R)-Ginsenoside Rg2 784.5
BXGC0025215 Lupeol 426.39
BXGC0025231 Betunolic Acid 454.34
BXGC0025793 24-hydroxy-beta-amyrin 442.38
BXGC0025887 5-Hydroxyflavone 238.06
BXGC0026832 zeylasterone 510.26
BXGC0027259 Tryptanthrin 248.06
BXGC0027406 ginsenoside Rd 946.55
BXGC0027430 ginsenoside Re 946.55
BXGC0027438 ginsenoside Rb1 1108.6
BXGC0027678 10-Hydroxyliriodenine 291.05
BXGC0028001 Beta-Lapachone 242.09
BXGC0028111 ginsenoside F5 770.48
BXGC0028425 Neobavaisoflavone 322.12
BXGC0028449 (+)-Ventiloquinone L Methyl Ether 302.12
BXGC0029291 Diphyllin 380.09
BXGC0029547 Lycobetaine 266.08
BXGC0029548 Ungeremine 265.07
BXGC0030138 Colchicine 399.17
BXGC0031622 Podofilox 414.13
BXGC0032283 3-(3,4-Dihydroxyphenyl)-7-Hydroxychromen-4-One 270.05
BXGC0032824 Kampferol 3-glucoside 7-rhamnoside 594.16
BXGC0032936 Echinatin 270.09
BXGC0033154 lespenefril 578.16
BXGC0034126 Kaempferol 3-O-Rha(1-2)Glc 7-O-Rha 740.22
BXGC0034637 Aesculioside Iv-23D1 1124.58
BXGC0034783 Doxorubicin 543.17
BXGC0035226 Betulinic Acid 456.36
BXGC0036649 Quinovic acid 3-O-beta-D-glucoside 648.39
BXGC0036911 kaempferol 3-O-alpha-L-arabinopyranosyl-7-O-alpha-L-rhamnopyranoside 564.15
BXGC0037016 4'-Methoxyflavone 252.08
BXGC0037048 (S)-7,9-Dimethoxy-3-Methyl-3,4-Dihydro-1H-Benzo[G]Isochromene-5,10-Dione 288.1
BXGC0037083 Alpha-Amyrin 426.39
BXGC0037313 gypenoside IX 916.54
BXGC0038316 Cholesterol 386.35
BXGC0040778 Zygophyloside E 810.44
BXGC0041449 Degalactotigonin 1034.53
BXGC0042236 ginsenoside F2 784.5
BXGC0042376 Picropodophyllotoxin 414.13
BXGC0045342 n.a 602.35
BXGC0045343 [acetoxy-tetrahydroxy-(hydroxymethyl)-isopropenyl-dimethyl-oxo-[?]yl] (2E,4E)-trideca-2,4-dienoate 646.34
BXGC0045345 1,3,3aalpha,4,9,9aalpha-Hexahydro-3alpha-(4-hydroxy-3-methoxyphenyl)-7-methoxynaphtho[2,3-c]furan-6-ol 342.15
BXGC0046055 Huratoxin 584.33
BXGC0047402 Acridine 179.07
BXGC0047692 Gefitinib 446.15
BXGC0047871 7-Hydroxyflavone 238.06
BXGC0049572 Gypenoside XVII 946.55
BXGC0049906 n.a 606.16
BXGC0050657 Dehydrokuanoniamine B 400.14
BXGC0051140 20(R)-ginsenoside Rg3 784.5
BXGC0053512 Vittatine 271.12
BXGC0053763 Frangulin B 402.1
The  target protein-related  foods
Foods
BXGF Id Food Name Scientific Name Food Group Number of compound? Number of compound in food, higher numbers indicate the food are more associated with the protein