acompound

Showing entry for Pinocembrin

General Compound Information
BXGC Id	BXGC0032310
Compound Name	Pinocembrin
Structure
Formula	C15H12O4
InchiKey	URFCJEUYXNAHFI-ZDUSSCGKSA-N
SMILES	Oc1cc2O[C@@H](CC(=O)c2c(c1)O)c1ccccc1
Inchi	InChI=1S/C15H12O4/c16-10-6-11(17)15-12(18)8-13(19-14(15)7-10)9-4-2-1-3-5-9/h1-7,13,16-17H,8H2/t13-/m0/s1
IUPAC	(2S)-5,7-dihydroxy-2-phenyl-2,3-dihydrochromen-4-one
Molecular Weight	256.07
Pubchem Id	68071
Chembl Id	CHEMBL399910

Targets of Information Source

DrugBank

n.a

Uniport Id	BXGT Id	Protein Name	Status	Protein Class	Gene	Groups	Target Type
Uniport Id	BXGT Id	Protein Name	Status	Protein Class	Gene	Groups	Target Type

PDB

n.a

Uniport Id	BXGT Id	Protein Name	Status	Protein Class	Gene	Ki nM	ic50 nM	Kd nM	Ka M-1
Uniport Id	BXGT Id	Protein Name	Status	Protein Class	Gene	Ki nM	ic50 nM	Kd nM	Ka M-1

Binding DB

26667

Uniport Id	BXGT Id	Protein Name	Status	Protein Class	Gene	Ki nM	ic50 nM	Kd nM	EC50 nM
Uniport Id	BXGT Id	Protein Name	Status	Protein Class	Gene	Ki nM	ic50 nM	Kd nM	EC50 nM
reviewed	BXGT007685	Serine/threonine-protein kinase pim-1	reviewed	Kinase	PIM1	-	107000	-	-
reviewed	BXGT006265	Cytochrome P450 1A1	reviewed	Enzyme	CYP1A1	-	7906	-	-
reviewed	BXGT013656	Cytochrome P450 1B1	reviewed	Enzyme	CYP1B1	-	1679	-	-

CHEMBL

CHEMBL399910

Uniport Id	BXGT Id	Protein Name	Status	Protein Class	Gene	width="10%">Type	Relation	value	Units
Uniport Id	BXGT Id	Protein Name	Status	Protein Class	Gene	Type	Relation	value	Units
P30561	BXGT009444	Aryl hydrocarbon receptor	reviewed	-	Ahr	FC	'='	8	-
O14763	BXGT004093	Tumor necrosis factor receptor superfamily member 10B	reviewed	-	TNFRSF10B	FC	'='	2	-
Q9Y6L6	BXGT022334	Solute carrier organic anion transporter family member 1B1	reviewed	Transporter	SLCO1B1	Inhibition	'='	201	%
P30561	BXGT009444	Aryl hydrocarbon receptor	reviewed	-	Ahr	Activity	-	-	-
Q9NPD5	BXGT021151	Solute carrier organic anion transporter family member 1B3	reviewed	Transporter	SLCO1B3	Inhibition	'='	97	%
P11309	BXGT007685	Serine/threonine-protein kinase pim-1	reviewed	Kinase	PIM1	#NAME?	'='	-2	uM
P83916	BXGT012025	Chromobox protein homolog 1	reviewed	Epigenetic regulator	CBX1	Potency	-	100000	nM
Q965D5	BXGT019600	Enoyl-acyl-carrier protein reductase	unreviewed	-	fabI	IC50	-	-	-
P81908	BXGT011959	Cholinesterase	reviewed	-	BCHE	Inhibition	'='	1	%
Q16678	BXGT013656	Cytochrome P450 1B1	reviewed	Enzyme	CYP1B1	IC50	'='	1679	nM
P11309	BXGT007685	Serine/threonine-protein kinase pim-1	reviewed	Kinase	PIM1	IC50	'='	107000	nM
P29990	BXGT009390	Genome polyprotein	reviewed	-		Inhibition	'='	30	%
P04798	BXGT006265	Cytochrome P450 1A1	reviewed	Enzyme	CYP1A1	IC50	'='	7906	nM
P05177	BXGT006336	Cytochrome P450 1A2	reviewed	Enzyme	CYP1A2	IC50	'='	1491	nM
P29990	BXGT009390	Genome polyprotein	reviewed	-		Inhibition	'='	47	%
P08047	BXGT006720	Transcription factor Sp1	reviewed	Nucleic acid binding	SP1	Activity	-	-	-
P29990	BXGT009390	Genome polyprotein	reviewed	-		Inhibition	'='	56	%
P11511	BXGT007717	Aromatase	reviewed	Enzyme	CYP19A1	IC50	'='	900	nM
O42275	BXGT004559	Acetylcholinesterase	reviewed	-	ache	Inhibition	'='	27	%
P63092	BXGT011495	Guanine nucleotide-binding protein G(s) subunit alpha isoforms short	reviewed	-	GNAS	Potency	-	7943	nM
P93836	BXGT012125	4-hydroxyphenylpyruvate dioxygenase	reviewed	-	HPD	IC50	'='	73000	nM

Foods containing the compound

Foods

BXGF Id	Food Name	Scientific Name	Food Group
BXGF Id	Food Name	Scientific Name	Food Group
BXGF00151	Pomegranate	Punica granatum	Fruits
BXGF00305	Chinese chestnut	Castanea mollissima	Nuts
BXGF00353	Java plum	Syzygium cumini	Fruits
BXGF00380	White mustard	Sinapis alba	Herbs and Spices
BXGF00857	Mitracarpus scaber	Mitracarpus scaber	Others
BXGF00861	Abies pinsapo var. marocana	Abies pinsapo var. marocana	Others
BXGF00884	Eria linearifolia	Eria linearifolia	Others
BXGF00900	Melaleuca cuticularis	Melaleuca cuticularis	Others
BXGF00921	Gaillardia coahuilensis	Gaillardia coahuilensis	Others
BXGF01035	Maackia tashiroi	Maackia tashiroi	Others
BXGF01104	Garcinia cambogia	Garcinia cambogia	Medicinal Plant
BXGF01115	Eriodictyon californicum	Eriodictyon californicum	Medicinal Plant
BXGF01248	Pinus banksiana	Pinus banksiana	Medicinal Plant
BXGF01250	Colchicum filifolium	Colchicum filifolium	Others
BXGF01252	Petasites laevigatus	Petasites laevigatus	Medicinal Plant
BXGF01256	Cynoglossum macrostylum	Cynoglossum macrostylum	Others
BXGF01355	Amomum krervanh	Amomum krervanh	Medicinal Plant
BXGF01404	Sphaeranthus confertifolius	Sphaeranthus confertifolius	Others
BXGF01497	Polypodiodes niponica	Polypodiodes niponica	Human Edible Plant
BXGF01556	Ornithoglossum viride	Ornithoglossum viride	Others
BXGF01562	Strychnos tomentosa	Strychnos tomentosa	Others
BXGF01606	Schizanthus tricolor	Schizanthus tricolor	Others
BXGF01631	Anodendron affine	Anodendron affine	Medicinal Plant
BXGF01632	Euphrasia genargentea	Euphrasia genargentea	Others
BXGF01669	Hertia cheirifolia	Hertia cheirifolia	Others
BXGF01686	Pulsatilla chinensis	Pulsatilla chinensis	Medicinal Plant
BXGF01720	Cedrela salvadorensis	Cedrela salvadorensis	Others
BXGF01768	Dalbergia parviflora	Dalbergia parviflora	Medicinal Plant
BXGF01857	Acer saccharum	Acer saccharum	Medicinal Plant
BXGF01859	Walsura yunnanensis	Walsura yunnanensis	Others
BXGF01892	Xanthorhiza simplicissima	Xanthorhiza simplicissima	Medicinal Plant
BXGF01925	Pelargonium x hortorum	Pelargonium x hortorum	Human Edible Plant
BXGF02005	Polyachyrus sphaerocephalus	Polyachyrus sphaerocephalus	Others
BXGF02131	Glycyrrhiza	Glycyrrhiza	Medicinal Plant
BXGF02206	Mucuna holtonii	Mucuna holtonii	Others
BXGF02233	Quercus marilandica	Quercus marilandica	Medicinal Plant
BXGF02328	Dalbergia nitidula	Dalbergia nitidula	Medicinal Plant
BXGF02381	Glycyrrhiza inflata	Glycyrrhiza inflata	Medicinal Plant
BXGF02383	Persea obovatifolia	Persea obovatifolia	Others
BXGF02404	Pittocaulon bombycophole	Pittocaulon bombycophole	Others
BXGF02446	Centaurea scoparia	Centaurea scoparia	Others
BXGF02626	Dalbergia odorifera	Dalbergia odorifera	Medicinal Plant
BXGF02775	Aconitum contortum	Aconitum contortum	Others
BXGF02832	Acanthosyris paulo-alvinii	Acanthosyris paulo-alvinii	Human Edible Plant
BXGF02938	Uvaria lucida	Uvaria lucida	Human Edible Plant
BXGF03021	Turnera diffusa	Turnera diffusa	Medicinal Plant
BXGF03022	Afraegle paniculata	Afraegle paniculata	Medicinal Plant
BXGF03054	Mimosa pigra	Mimosa pigra	Medicinal Plant
BXGF03080	Cratoxylum pruniflorum	Cratoxylum pruniflorum	Medicinal Plant
BXGF03142	Soymida febrifuga	Soymida febrifuga	Medicinal Plant
BXGF03189	Rhododendron dauricum	Rhododendron dauricum	Medicinal Plant
BXGF03216	Neolitsea villosa	Neolitsea villosa	Others
BXGF03231	Dactylorhiza viridis	Dactylorhiza viridis	Others
BXGF03271	Pterolobium hexapetalum	Pterolobium hexapetalum	Medicinal Plant
BXGF03454	Saussurea salicifolia	Saussurea salicifolia	Others
BXGF03527	Alpinia oxyphylla	Alpinia oxyphylla	Medicinal Plant
BXGF03600	Callistemon coccineus	Callistemon coccineus	Others
BXGF03601	Maclura cochinchinensis	Maclura cochinchinensis	Medicinal Plant
BXGF03620	Cassinia subtropica	Cassinia subtropica	Others
BXGF03622	Justicia betonica	Justicia betonica	Medicinal Plant
BXGF03636	Hypericum reptans	Hypericum reptans	Others
BXGF03655	Uncaria africana	Uncaria africana	Medicinal Plant
BXGF03670	Strychnos amazonica	Strychnos amazonica	Medicinal Plant
BXGF03687	Alpinia zerumbet	Alpinia zerumbet	Medicinal Plant
BXGF03701	Escontria chiotilla	Escontria chiotilla	Human Edible Plant
BXGF03719	Rubus laciniatus	Rubus laciniatus	Medicinal Plant
BXGF03732	Grazielia serrata	Grazielia serrata	Others
BXGF03755	Eucryphia cordifolia	Eucryphia cordifolia	Others
BXGF03770	Buxus hildebrandtii	Buxus hildebrandtii	Others
BXGF03778	Drypetes tessmanniana	Drypetes tessmanniana	Others
BXGF03790	Pteryxia terebinthina	Pteryxia terebinthina	Others
BXGF03805	Gratiola officinalis	Gratiola officinalis	Medicinal Plant
BXGF03813	Diplopterygium glaucum	Diplopterygium glaucum	Others
BXGF03818	Rhizophora tagal	Rhizophora tagal	Others
BXGF03825	Salvia lavandulifolia	Salvia lavandulifolia	Medicinal Plant
BXGF03835	Echinacea simulata	Echinacea simulata	Others
BXGF03850	Cotinus coggygria	Cotinus coggygria	Medicinal Plant
BXGF03854	Grindelia discoidea	Grindelia discoidea	Others
BXGF03869	Eremurus chinensis	Eremurus chinensis	Others
BXGF03872	Lycopodium japonicum	Lycopodium japonicum	Medicinal Plant
BXGF03900	Pachygone dasycarpa	Pachygone dasycarpa	Others
BXGF03905	Croton geayi	Croton geayi	Others
BXGF03918	Callicarpa acuminata	Callicarpa acuminata	Human Edible Plant
BXGF03920	Kaempferia pandurata	Kaempferia pandurata	Medicinal Plant
BXGF03921	Agave xylonacantha	Agave xylonacantha	Others
BXGF03923	Ageratum mexicanum	Ageratum mexicanum	Others
BXGF03936	Petunia nyctaginiflora	Petunia nyctaginiflora	Medicinal Plant
BXGF03956	Arnica parryi	Arnica parryi	Others
BXGF03983	Kalanchoe spathulata	Kalanchoe spathulata	Medicinal Plant
BXGF04035	Campanula choziatowskyi	Campanula choziatowskyi	Others
BXGF04200	Euphorbia hirta	Euphorbia hirta	Medicinal Plant
BXGF04208	Salvia patens	Salvia patens	Others
BXGF04214	Dialium excelsum	Dialium excelsum	Others
BXGF04296	Maytenus chuchuhuasha	Maytenus chuchuhuasha	Others
BXGF04372	Kniphofia foliosa	Kniphofia foliosa	Human Edible Plant
BXGF04380	Euphorbia hylonoma	Euphorbia hylonoma	Others
BXGF04390	Centaurea cheiranthifolia	Centaurea cheiranthifolia	Others
BXGF04407	Sideritis lanata	Sideritis lanata	Others
BXGF04409	Senecio platyphylloides	Senecio platyphylloides	Others
BXGF04418	Drymaria cordata	Drymaria cordata	Medicinal Plant
BXGF04433	Lamprolobium fruticosum	Lamprolobium fruticosum	Others
BXGF04442	Boesenbergia pandurata	Boesenbergia pandurata	Medicinal Plant
BXGF04444	Erythrina burttii	Erythrina burttii	Medicinal Plant
BXGF04447	Helleborus macranthus	Helleborus macranthus	Others
BXGF04448	Salix rosmarinifolia	Salix rosmarinifolia	Others
BXGF04455	Heliotropium scabrum	Heliotropium scabrum	Others
BXGF04457	Podocarpus dacrydioides	Podocarpus dacrydioides	Medicinal Plant
BXGF04458	Oxytropis falcata	Oxytropis falcata	Others
BXGF04466	Mikania grazielae	Mikania grazielae	Others
BXGF04468	Mentha pulegium	Mentha pulegium	Medicinal Plant
BXGF04469	Centaurea sonchifolia	Centaurea sonchifolia	Others
BXGF04472	Matricaria sabulosa	Matricaria sabulosa	Others
BXGF04489	Pterocaulon serrulatum	Pterocaulon serrulatum	Medicinal Plant
BXGF04497	Laggera aurita	Laggera aurita	Medicinal Plant
BXGF04501	Viola hondoensis	Viola hondoensis	Others
BXGF04504	Boswellia ovalifoliolata	Boswellia ovalifoliolata	Medicinal Plant
BXGF04509	Rubus pungens	Rubus pungens	Medicinal Plant
BXGF04515	Hardenbergia violacea	Hardenbergia violacea	Medicinal Plant
BXGF04529	Lonchocarpus chiricanus	Lonchocarpus chiricanus	Others
BXGF04533	Astragalus circassicus	Astragalus circassicus	Others
BXGF04535	Pinus pumila	Pinus pumila	Medicinal Plant
BXGF04541	Calophyllum inophyllum	Calophyllum inophyllum	Medicinal Plant
BXGF04543	Erythrina hypaphorus	Erythrina hypaphorus	Others
BXGF04544	Piper callosum	Piper callosum	Medicinal Plant
BXGF04547	Gyrothyra underwoodiana	Gyrothyra underwoodiana	Others
BXGF04548	Beilschmiedia madang	Beilschmiedia madang	Medicinal Plant
BXGF04552	Dianella revoluta	Dianella revoluta	Medicinal Plant
BXGF04555	Salvia lavanduloides	Salvia lavanduloides	Others
BXGF04563	Tamarix gallica	Tamarix gallica	Medicinal Plant
BXGF04573	Rubia akane	Rubia akane	Medicinal Plant
BXGF04577	Poterium sanguisorba	Poterium sanguisorba	Medicinal Plant
BXGF04579	Hardwickia pinnata	Hardwickia pinnata	Others
BXGF04586	Aniba santalodora	Aniba santalodora	Others
BXGF04587	Salvia dichroa	Salvia dichroa	Others
BXGF04604	Viguiera pinnatilobata	Viguiera pinnatilobata	Others
BXGF04611	Artemisia argyi	Artemisia argyi	Medicinal Plant
BXGF04617	Daphnandra johnsonii	Daphnandra johnsonii	Others
BXGF04618	Mentzelia decapetala	Mentzelia decapetala	Human Edible Plant
BXGF04623	Colchicum arenarium	Colchicum arenarium	Others
BXGF04630	Cladanthus arabicus	Cladanthus arabicus	Others
BXGF04635	Kokoona ochracea	Kokoona ochracea	Medicinal Plant
BXGF04648	Amorphophallus konjac	Amorphophallus konjac	Human Edible Plant
BXGF04660	Piper sarmentosum	Piper sarmentosum	Medicinal Plant
BXGF04675	Astragalus glycyphyllos	Astragalus glycyphyllos	Medicinal Plant
BXGF04681	Athrixia elata	Athrixia elata	Human Edible Plant
BXGF04687	Adina trichotoma	Adina trichotoma	Others
BXGF04690	Hippeastrum aulicum	Hippeastrum aulicum	Others
BXGF04691	Oroxylum indicum	Oroxylum indicum	Medicinal Plant
BXGF04723	Afrocarpus gracilior	Afrocarpus gracilior	Others
BXGF04842	Angelica acutiloba	Angelica acutiloba	Medicinal Plant
BXGF04849	Pinus excelsa	Pinus excelsa	Medicinal Plant
BXGF04872	Glycyrrhiza glabra	Glycyrrhiza glabra	Medicinal Plant
BXGF04897	Alstonia spectabilis	Alstonia spectabilis	Medicinal Plant
BXGF04976	Arachniodes exilis	Arachniodes exilis	Medicinal Plant
BXGF04994	Anthemis cretica	Anthemis cretica	Medicinal Plant
BXGF05009	Solanum lanceolatum	Solanum lanceolatum	Medicinal Plant
BXGF05067	Bryonia alba	Bryonia alba	Medicinal Plant
BXGF05141	Viburnum erubescens	Viburnum erubescens	Medicinal Plant
BXGF05149	Amentotaxus argotaenia	Amentotaxus argotaenia	Others
BXGF05156	Ardisia japonica	Ardisia japonica	Medicinal Plant
BXGF05226	Scutia buxifolia	Scutia buxifolia	Medicinal Plant
BXGF05231	Salvia virgata	Salvia virgata	Human Edible Plant
BXGF05293	Remirea maritima	Remirea maritima	Others
BXGF05326	Aglaia perviridis	Aglaia perviridis	Human Edible Plant
BXGF05364	Arnica mollis	Arnica mollis	Others
BXGF05436	Rubia tetragona	Rubia tetragona	Others
BXGF05459	Vachellia pennatula	Vachellia pennatula	Medicinal Plant
BXGF05498	Croton gratissimus	Croton gratissimus	Medicinal Plant
BXGF05508	Oocystis polymorpha	Oocystis polymorpha	Others
BXGF05559	Wikstroemia viridiflora	Wikstroemia viridiflora	Medicinal Plant
BXGF05566	Petunia axillaris subsp. parodii	Petunia axillaris subsp. parodii	Medicinal Plant
BXGF05584	Brassica carinata	Brassica carinata	Medicinal Plant
BXGF05587	Phoebe grandis	Phoebe grandis	Others
BXGF05685	Rubus pileatus	Rubus pileatus	Others
BXGF05713	Antiphiona pinnatisecta	Antiphiona pinnatisecta	Others
BXGF05725	Ranunculus asiaticus	Ranunculus asiaticus	Others
BXGF05736	Eurycoma harmandiana	Eurycoma harmandiana	Medicinal Plant
BXGF05790	Glycyrrhiza uralensis	Glycyrrhiza uralensis	Medicinal Plant
BXGF05840	Eucalyptus resinifera	Eucalyptus resinifera	Medicinal Plant
BXGF05858	Ormosia hosiei	Ormosia hosiei	Medicinal Plant
BXGF05984	Cressa cretica	Cressa cretica	Medicinal Plant
BXGF05990	Carpha glomerata	Carpha glomerata	Others
BXGF06081	Xylopia emarginata	Xylopia emarginata	Others
BXGF06093	Cyanostegia angustifolia	Cyanostegia angustifolia	Others
BXGF06122	Bethencourtia palmensis	Bethencourtia palmensis	Others
BXGF06149	Orthosiphon spicatus	Orthosiphon spicatus	Medicinal Plant
BXGF06151	Scutellaria lateriflora	Scutellaria lateriflora	Others
BXGF06159	Pseudocyclosorus subochthodes	Pseudocyclosorus subochthodes	Others
BXGF06192	Parkia clappertoniana	Parkia clappertoniana	Human Edible Plant
BXGF06203	Lepechinia urbanii	Lepechinia urbanii	Others
BXGF06209	Jacobaea argunensis	Jacobaea argunensis	Others
BXGF06239	Pericopsis angolensis	Pericopsis angolensis	Medicinal Plant
BXGF06249	Enicosanthum cupulare	Enicosanthum cupulare	Others
BXGF06250	Licaria chrysophylla	Licaria chrysophylla	Others
BXGF06254	Lysimachia fordiana	Lysimachia fordiana	Others
BXGF06278	Ampelocera edentula	Ampelocera edentula	Others
BXGF06301	Oricia gabonensis	Oricia gabonensis	Others
BXGF06304	Ixeris debilis	Ixeris debilis	Others
BXGF06309	Betula alnoides	Betula alnoides	Medicinal Plant
BXGF06329	Abies excelsa	Abies excelsa	Others

The compound-realted diseases

Diseases

BXGD Id	Disease Name	CUI Disease Id	Disease Class Name	Number of targets^{?Number of targets related to compound connecting disease, higher numbers indicate the compound is more associated with the disease}