acompound

Showing entry for Dimedazol

　　　　　　　　　　　　　　　

General Compound Information
BXGC Id	BXGC0040248
Compound Name	Dimedazol
Structure
Formula	C9H10N2
InchiKey	LJUQGASMPRMWIW-UHFFFAOYSA-N
SMILES	Cc1cc2[nH]cnc2cc1C
Inchi	InChI=1S/C9H10N2/c1-6-3-8-9(4-7(6)2)11-5-10-8/h3-5H,1-2H3,(H,10,11)
IUPAC	5,6-dimethyl-1H-benzimidazole
Molecular Weight	146.08
Pubchem Id	675
Chembl Id	CHEMBL351132

Targets of Information Source

DrugBank

Uniport Id	BXGT Id	Protein Name	Status	Protein Class	Gene	Groups	Target Type
Uniport Id	BXGT Id	Protein Name	Status	Protein Class	Gene	Groups	Target Type
Q05603	BXGT012829	Nicotinate-nucleotide--dimethylbenzimidazole phosphoribosyltransferase	reviewed	-	cobT	experimental	-

PDB

Uniport Id	BXGT Id	Protein Name	Status	Protein Class	Gene	Ki nM	ic50 nM	Kd nM	Ka M-1
Uniport Id	BXGT Id	Protein Name	Status	Protein Class	Gene	Ki nM	ic50 nM	Kd nM	Ka M-1
Q05603	BXGT012829	Nicotinate-nucleotide--dimethylbenzimidazole phosphoribosyltransferase	reviewed	cobT	-	-	-	-	-
Q6B0I6	BXGT016211	Lysine-specific demethylase 4D	reviewed	KDM4D	Epigenetic regulator	-	-	-	-
F6MZ55	BXGT003298	Nicotinate-nucleotide--dimethylbenzimidazole phosphoribosyltransferase	unreviewed	arsA	-	-	-	-	-

Binding DB

Uniport Id	BXGT Id	Protein Name	Status	Protein Class	Gene	Ki nM	ic50 nM	Kd nM	EC50 nM
Uniport Id	BXGT Id	Protein Name	Status	Protein Class	Gene	Ki nM	ic50 nM	Kd nM	EC50 nM
reviewed	BXGT005484	Cytochrome P450 1A1	reviewed		Cyp1a1	-	97000	-	-
reviewed	BXGT010602	Xanthine dehydrogenase/oxidase	reviewed	Enzyme	XDH	-	>200000	-	-
reviewed	BXGT005484	Cytochrome P450 1A1	reviewed		Cyp1a1	-	97723.72	-	-
reviewed	BXGT005479	Cytochrome P450 2B1	reviewed		Cyp2b1	-	181970.09	-	-
reviewed	BXGT005479	Cytochrome P450 2B1	reviewed		Cyp2b1	-	180000	-	-

CHEMBL

Uniport Id	BXGT Id	Protein Name	Status	Protein Class	Gene	width="10%">Type	Relation	value	Units
Uniport Id	BXGT Id	Protein Name	Status	Protein Class	Gene	Type	Relation	value	Units
P47989	BXGT010602	Xanthine dehydrogenase/oxidase	reviewed	Enzyme	XDH	IC50	'>'	200000	nM
P00185	BXGT005484	Cytochrome P450 1A1	reviewed	-	Cyp1a1	IC50	'='	97000	nM
P00176	BXGT005479	Cytochrome P450 2B1	reviewed	-	Cyp2b1	IC50	'='	180000	nM
Q64133	BXGT016109	Amine oxidase [flavin-containing] A	reviewed	-	Maoa	Activity	-	-	-
P00185	BXGT005484	Cytochrome P450 1A1	reviewed	-	Cyp1a1	Ks	'='	0	M
Q8BW75	BXGT017924	Amine oxidase [flavin-containing] B	reviewed	-	Maob	Activity	-	-	-
P00176	BXGT005479	Cytochrome P450 2B1	reviewed	-	Cyp2b1	IC50	'='	181970	nM
P00185	BXGT005484	Cytochrome P450 1A1	reviewed	-	Cyp1a1	IC50	'='	97723	nM
P00185	BXGT005484	Cytochrome P450 1A1	reviewed	-	Cyp1a1	Control	'='	69	%
P00176	BXGT005479	Cytochrome P450 2B1	reviewed	-	Cyp2b1	Ks	'='	0	M

Foods containing the compound

Foods

BXGF Id	Food Name	Scientific Name	Food Group
BXGF Id	Food Name	Scientific Name	Food Group
BXGF02182	Atractylodes lancea	Atractylodes lancea	Medicinal Plant
BXGF03162	Atractylodes macrocephala	Atractylodes macrocephala	Medicinal Plant

The compound-realted diseases

Diseases

BXGD Id	Disease Name	CUI Disease Id	Disease Class Name	Number of targets^{?Number of targets related to compound connecting disease, higher numbers indicate the compound is more associated with the disease}