acompound

Showing entry for D-glucuronic acid

General Compound Information
BXGC Id	BXGC0040471
Compound Name	D-glucuronic acid
Structure
Formula	C6H10O7
InchiKey	AEMOLEFTQBMNLQ-QIUUJYRFSA-N
SMILES	O[C@@H]1O[C@H](C(=O)O)[C@H]([C@@H]([C@H]1O)O)O
Inchi	InChI=1S/C6H10O7/c7-1-2(8)4(5(10)11)13-6(12)3(1)9/h1-4,6-9,12H,(H,10,11)/t1-,2-,3+,4-,6+/m0/s1
IUPAC	(2S,3S,4S,5R,6R)-3,4,5,6-tetrahydroxyoxane-2-carboxylic acid
Molecular Weight	194.04
Pubchem Id	441478
Chembl Id	CHEMBL1159524

Targets of Information Source

DrugBank

DB03156

Uniport Id	BXGT Id	Protein Name	Status	Protein Class	Gene	Groups	Target Type
Uniport Id	BXGT Id	Protein Name	Status	Protein Class	Gene	Groups	Target Type
Q54873	BXGT015048	Hyaluronate lyase	reviewed	-	SP_0314	experimental	-
Q59288	BXGT015243	Chondroitinase-AC	reviewed	-	cslA	experimental	-
Q8VVD2	BXGT018955	Xylan alpha-1,2-glucuronidase	unreviewed	-	aguA	experimental	-

PDB

BDP

Uniport Id	BXGT Id	Protein Name	Status	Protein Class	Gene	Ki nM	ic50 nM	Kd nM	Ka M-1
Uniport Id	BXGT Id	Protein Name	Status	Protein Class	Gene	Ki nM	ic50 nM	Kd nM	Ka M-1
B3PC73	BXGT002059	Extracellular xylan exo-alpha-(1->2)-glucuronosidase	reviewed	gla67A	-	-	-	-	-
Q59288	BXGT015243	Chondroitinase-AC	reviewed	cslA	-	-	-	-	-
Q54873	BXGT015048	Hyaluronate lyase	reviewed	SP_0314	-	-	-	-	-
Q53591	BXGT014998	Hyaluronate lyase	reviewed	hylB	-	-	-	-	-
Q8CWU3	BXGT017952	Hyaluronate lyase (Hyaluronidase/hyase)	unreviewed	hysA	-	-	-	-	-
Q46079	BXGT014632	Chondroitinase-B	reviewed	cslB	-	-	-	-	-
Q9ES89	BXGT020317	Exostosin-like 2	reviewed	Extl2	-	-	-	-	-
P15379	BXGT008114	CD44 antigen	reviewed	Cd44	-	-	-	-	-
Q9DTZ2	BXGT020275	VAL-1	unreviewed	vAL-1	-	-	-	-	-
P43235	BXGT010368	Cathepsin K	reviewed	CTSK	Enzyme	-	-	-	-
Q45070	BXGT014610	Glucuronoxylanase XynC	reviewed	xynC	-	-	-	-	-
O35310	BXGT004524	Heparan sulfate glucosamine 3-O-sulfotransferase 1	reviewed	Hs3st1	-	-	-	-	-
P25548	BXGT009053	Multiple sugar-binding periplasmic receptor ChvE	reviewed	chvE	-	-	-	-	-
C1F2K5	BXGT002422	Uncharacterized protein	unreviewed	ACP_2665	-	-	-	-	-
Q62226	BXGT016026	Sonic hedgehog protein	reviewed	Shh	-	-	-	-	-
Q9I6P8	BXGT020772	Probable porin	unreviewed	PA0240	-	-	-	-	-
Q128M1	BXGT013277	Solute-binding protein Bpro_3107	reviewed	Bpro_3107	-	-	-	-	-
Q0B2F6	BXGT013058	Solute-binding protein Bamb_6123	reviewed	Bamb_6123	-	-	-	-	-
C7RDZ3	BXGT002610	TRAP dicarboxylate transporter, DctP subunit	unreviewed	Apre_1383	-	-	-	-	-
Q160Z9	BXGT013621	TRAP dicarboxylate ABC transporter, substrate-binding protein	unreviewed	dctP	-	-	-	-	-
Q1QUN2	BXGT013840	Solute-binding protein Csal_2479	reviewed	dctP	-	-	-	-	-
H6WCZ0	BXGT003611	Glucuronoarabinoxylan endo-1,4-beta-xylanase	unreviewed	xyn30d	-	-	-	-	-
A8AR30	BXGT001660	Uncharacterized protein	unreviewed	CKO_04899	-	-	-	-	-
A3PLM5	BXGT001178	TRAP dicarboxylate transporter, DctP subunit	unreviewed	Rsph17029_2138	-	-	-	-	-
I3UZ52	BXGT003683	TRAP dicarboxylate transporter subunit DctP	unreviewed	YSA_07416	-	-	-	-	-
Q9Y251	BXGT022215	Heparanase	reviewed	HPSE	Enzyme	-	-	-	-
Q60675	BXGT015994	Laminin subunit alpha-2	reviewed	Lama2	-	-	-	-	-
Q8A1H5	BXGT017784	Neuraminidase	unreviewed	BT_3686	-	-	-	-	-
E0QAF3	BXGT003048	Glycosyl hydrolase family 2, TIM barrel domain protein	unreviewed	uidA	-	-	-	-	-
C4Z6Z2	BXGT002502	Glycoside Hydrolase Family 2 candidate b-glucuronidase	unreviewed	EUBELI_20590	-	-	-	-	-
A0A084JZF2	BXGT000088	Uncharacterized protein	reviewed	IL45_01530	-	-	-	-	-
Q8AB46	BXGT017886	Beta-glucanase	unreviewed	BT_0265	-	-	-	-	-
O94923	BXGT024255	D-glucuronyl C5-epimerase	reviewed	GLCE	-	-	-	-	-
Q6W7J7	BXGT024560	Beta-galactosidase	unreviewed	uidA	-	-	-	-	-
B1ZMF4	BXGT001946	Putative acetyl xylan esterase	unreviewed	Oter_0116	-	-	-	-	-

Binding DB

n.a

Uniport Id	BXGT Id	Protein Name	Status	Protein Class	Gene	Ki nM	ic50 nM	Kd nM	EC50 nM
Uniport Id	BXGT Id	Protein Name	Status	Protein Class	Gene	Ki nM	ic50 nM	Kd nM	EC50 nM

CHEMBL

CHEMBL1159524

Uniport Id	BXGT Id	Protein Name	Status	Protein Class	Gene	width="10%">Type	Relation	value	Units
Uniport Id	BXGT Id	Protein Name	Status	Protein Class	Gene	Type	Relation	value	Units
P02768	BXGT005955	Serum albumin	reviewed	Transporter	ALB	Log B/F	'='	-2	-
Q8TCC7	BXGT018794	Solute carrier family 22 member 8	reviewed	Transporter	SLC22A8	Activity	-	-	-

Foods containing the compound

Foods

BXGF Id	Food Name	Scientific Name	Food Group
BXGF Id	Food Name	Scientific Name	Food Group
BXGF01185	Aloe vera	Aloe vera	Medicinal Plant
BXGF01900	Aloe ferox	Aloe ferox	Medicinal Plant
BXGF02131	Glycyrrhiza	Glycyrrhiza	Medicinal Plant
BXGF04631	Aloe spicata	Aloe spicata	Medicinal Plant
BXGF04820	Panax ginseng	Panax ginseng	0
BXGF04926	Aloe africana	Aloe africana	Medicinal Plant

The compound-realted diseases

Diseases

BXGD Id	Disease Name	CUI Disease Id	Disease Class Name	Number of targets^{?Number of targets related to compound connecting disease, higher numbers indicate the compound is more associated with the disease}