acompound

Showing entry for Pyrrole-2-Carboxylic Acid

　　　　　　　　　　　　　　　

General Compound Information
BXGC Id	BXGC0042626
Compound Name	Pyrrole-2-Carboxylic Acid
Structure
Formula	C5H5NO2
InchiKey	WRHZVMBBRYBTKZ-UHFFFAOYSA-N
SMILES	OC(=O)c1ccc[nH]1
Inchi	InChI=1S/C5H5NO2/c7-5(8)4-2-1-3-6-4/h1-3,6H,(H,7,8)
IUPAC	1H-pyrrole-2-carboxylic acid
Molecular Weight	111.03
Pubchem Id	12473
Chembl Id	CHEMBL509027

Targets of Information Source

DrugBank

Uniport Id	BXGT Id	Protein Name	Status	Protein Class	Gene	Groups	Target Type
Uniport Id	BXGT Id	Protein Name	Status	Protein Class	Gene	Groups	Target Type
P40859	BXGT010203	Monomeric sarcosine oxidase	reviewed	-	soxA	experimental	-

PDB

n.a

Uniport Id	BXGT Id	Protein Name	Status	Protein Class	Gene	Ki nM	ic50 nM	Kd nM	Ka M-1
Uniport Id	BXGT Id	Protein Name	Status	Protein Class	Gene	Ki nM	ic50 nM	Kd nM	Ka M-1

Binding DB

Uniport Id	BXGT Id	Protein Name	Status	Protein Class	Gene	Ki nM	ic50 nM	Kd nM	EC50 nM
Uniport Id	BXGT Id	Protein Name	Status	Protein Class	Gene	Ki nM	ic50 nM	Kd nM	EC50 nM
reviewed	BXGT008067	D-amino-acid oxidase	reviewed		DAO	-	>5000	-	-
reviewed	BXGT005519	D-amino-acid oxidase	reviewed		DAO	-	-	26000	-

CHEMBL

Uniport Id	BXGT Id	Protein Name	Status	Protein Class	Gene	width="10%">Type	Relation	value	Units
Uniport Id	BXGT Id	Protein Name	Status	Protein Class	Gene	Type	Relation	value	Units
P08254	BXGT006758	Stromelysin-1	reviewed	Enzyme	MMP3	Inhibition	'='	-8	%
P14780	BXGT008053	Matrix metalloproteinase-9	reviewed	Enzyme	MMP9	Inhibition	'='	-20	%
P03956	BXGT006120	Interstitial collagenase	reviewed	Enzyme	MMP1	Inhibition	'='	8	%
P08253	BXGT006757	72 kDa type IV collagenase	reviewed	Enzyme	MMP2	Inhibition	'='	1	%
P15917	BXGT008169	Lethal factor	reviewed	-	lef	Inhibition	'='	11	%
P22894	BXGT008815	Neutrophil collagenase	reviewed	Enzyme	MMP8	Inhibition	'='	-24	%
P14920	BXGT008067	D-amino-acid oxidase	reviewed	-	DAO	IC50	'>'	5000	nM
O42713	BXGT004563	Polyphenol oxidase 2	reviewed	-	PPO2	Inhibition	'='	69	%
P29477	BXGT009355	Nitric oxide synthase, inducible	reviewed	-	Nos2	Inhibition	'='	7	%
P00371	BXGT005519	D-amino-acid oxidase	reviewed	-	DAO	Kd	'='	26000	nM
P09917	BXGT006941	Arachidonate 5-lipoxygenase	reviewed	Enzyme	ALOX5	Inhibition	'='	48	%
P00371	BXGT005519	D-amino-acid oxidase	reviewed	-	DAO	IC50	'<'	10000	nM

Foods containing the compound

Foods

BXGF Id	Food Name	Scientific Name	Food Group
BXGF Id	Food Name	Scientific Name	Food Group
BXGF05705	Pseudostellaria heterophylla	Pseudostellaria heterophylla	Medicinal Plant
BXGF05800	Mimosa pudica	Mimosa pudica	Medicinal Plant

The compound-realted diseases

Diseases

BXGD Id	Disease Name	CUI Disease Id	Disease Class Name	Number of targets^{?Number of targets related to compound connecting disease, higher numbers indicate the compound is more associated with the disease}