acompound

Showing entry for Levoleucovorin

　　　　　　　　　　　　　　　

General Compound Information
BXGC Id	BXGC0052047
Compound Name	Levoleucovorin
Structure
Formula	C20H23N7O7
InchiKey	VVIAGPKUTFNRDU-STQMWFEESA-N
SMILES	O=CN1[C@@H](CNc2ccc(cc2)C(=O)N[C@H](C(=O)O)CCC(=O)O)CNc2c1c(O)nc(=N)[nH]2
Inchi	InChI=1S/C20H23N7O7/c21-20-25-16-15(18(32)26-20)27(9-28)12(8-23-16)7-22-11-3-1-10(2-4-11)17(31)24-13(19(33)34)5-6-14(29)30/h1-4,9,12-13,22H,5-8H2,(H,24,31)(H,29,30)(H,33,34)(H4,21,23,25,26,32)/t12-,13-/m0/s1
IUPAC	(2S)-2-[[4-[[(6S)-2-amino-5-formyl-4-oxo-1,6,7,8-tetrahydropteridin-6-yl]methylamino]benzoyl]amino]pentanedioic acid
Molecular Weight	473.17
Pubchem Id	135398559
Chembl Id	CHEMBL1908841

Targets of Information Source

DrugBank

Uniport Id	BXGT Id	Protein Name	Status	Protein Class	Gene	Groups	Target Type
Uniport Id	BXGT Id	Protein Name	Status	Protein Class	Gene	Groups	Target Type
P0A827	BXGT007131	Serine hydroxymethyltransferase	reviewed	-	glyA	approved; investigational	-

PDB

Uniport Id	BXGT Id	Protein Name	Status	Protein Class	Gene	Ki nM	ic50 nM	Kd nM	Ka M-1
Uniport Id	BXGT Id	Protein Name	Status	Protein Class	Gene	Ki nM	ic50 nM	Kd nM	Ka M-1
P0A825	BXGT007130	Serine hydroxymethyltransferase	reviewed	glyA	-	-	-	-	-
P0ABQ4	BXGT007239	Dihydrofolate reductase	reviewed	folA	-	-	-	-	-
Q9AGP8	BXGT020063	Dimethylglycine oxidase	reviewed	dmg	-	-	-	-	-
Q9WY54	BXGT021973	Aminomethyltransferase	reviewed	gcvT	-	-	-	-	-
Q7SIB6	BXGT017110	Serine hydroxymethyltransferase	unreviewed	glyA	-	-	-	-	-
Q834R3	BXGT022711	Thymidylate synthase	reviewed	thyA	-	-	-	-	-
Q9WYT0	BXGT022003	Flavin-dependent thymidylate synthase	reviewed	thyX	-	-	-	-	-
P04818	BXGT006269	Thymidylate synthase	reviewed	TYMS	Enzyme	-	-	-	-
A0A0R0IK90	BXGT025767	Serine hydroxymethyltransferase	unreviewed	100305380	-	-	-	-	-

Binding DB

Uniport Id	BXGT Id	Protein Name	Status	Protein Class	Gene	Ki nM	ic50 nM	Kd nM	EC50 nM
Uniport Id	BXGT Id	Protein Name	Status	Protein Class	Gene	Ki nM	ic50 nM	Kd nM	EC50 nM
reviewed	BXGT011672	Solute carrier organic anion transporter family member 1A3	reviewed		Slco1a3	8200	-	-	-

CHEMBL

Uniport Id	BXGT Id	Protein Name	Status	Protein Class	Gene	width="10%">Type	Relation	value	Units
Uniport Id	BXGT Id	Protein Name	Status	Protein Class	Gene	Type	Relation	value	Units

Foods containing the compound

Foods

BXGF Id	Food Name	Scientific Name	Food Group
BXGF Id	Food Name	Scientific Name	Food Group
BXGF00040	Pepper (C. annuum)	Capsicum annuum	Vegetables
BXGF01140	Angelica gigas	Angelica gigas	Medicinal Plant
BXGF02049	Angelica sinensis	Angelica sinensis	Medicinal Plant
BXGF04842	Angelica acutiloba	Angelica acutiloba	Medicinal Plant

The compound-realted diseases

Diseases

BXGD Id	Disease Name	CUI Disease Id	Disease Class Name	Number of targets^{?Number of targets related to compound connecting disease, higher numbers indicate the compound is more associated with the disease}